용매추출과 원자흡수분광법에 의한 망간(Ⅱ)의 분리 및 분석에 관한 연구

정창웅,심유상 순천향대학교 기초과학연구소 2004 순천향자연과학연구 논문집 Vol.10 No.2

The extraction of Manganese form industrial wastewater and wastes are very important. A method is described for the separation and determination of Manganese(Ⅱ) with 0.4M-potassium thiocyanate and 3% Aliquat 336-CC14 by liquid-liquid extraction and flame atomic absorption spectrometry. Managanese(Ⅱ) have been stripped into HCI solution in the presence of foreign ions. Calibration curve showed that Beer's law obey in the range of 7 ppm. Determination of Manganese(Ⅱ) in seawater was performed by the proposed method.

액체-액체추출과 원자흡수분광법에 의한 크롬(Ⅲ)의 분리 및 분석에 관한 연구

심유상,정창웅 순천향대학교 기초과학연구소 2003 순천향자연과학연구 논문집 Vol.9 No.1

A method is described for the separation and determination of chromium(Ⅲ) with 2M-thiocyanate and 3% Aliquat 336-CCI₄ by flame atomic abstorption spectrometry. Beer's law obeys in the range of 14 ppm. The proposed method was applied for the analysis of chromium(Ⅲ) in seawater.

우리나라 일부여성의 임신출산에 대한 태도조사

전정자,유은광,이정섭 최신의학사 1988 最新醫學 Vol.31 No.2

각종 조리방법이 간흡충 피낭유충의 저항성에 미치는 연구

조유정,주종필,임한종,황선경,이성희 한국건강관리협회 2000 건협 Report Vol.3 No.-

한국어판 소아기 자폐증평가척도의 타당도와 신뢰도 연구

소은희,정유숙 大韓神經精神醫學會 1992 신경정신의학 Vol.31 No.3

Korean version of the Childhood Autism Rating Scale(CARS) ws used with 41 developmentally disabled children under age 11. Cronbach's coefficient alpha was 0.94. The interrater reliability(γ) for each of the 15 scales ranged from 0.61 to 0.92 with an average of 0.76. The total GARS score or number of item above 3 score demonstrated a statistically significant correlation with social age. But the total CARS score or number of item above 3 score demonstrated an unsatisfactory correlation with social quotients. The authors suggest that the development of assessmental instrument for infantile autism and concurrent use of Krug's “Autism Behavior Checklist” will be needed.

주의력 결핍 과잉행동 장애 아동에서의 집단 프로그램의 치료 효과

심세훈,오창근,권자영,정유숙,홍성도 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

Background : The authors attempted to introduce group program for improving interpersonal relationship and evaluate the effects of that program. Material and Methods : This program had been held twice a week for 8 weeks for children and parents training had been for times on the treatment and continued from 2001 to 2002. Twenty-five ADHD children in school age were selected as subjects from child psychiatric clinic of a general hospital in Seoul. Treatment outcomes were evaluated by comparing at pre- and post- treatment using the various rating scale. Result : According to the results of statistical analysis, paired t-test, the score of total self-concept including popularity was increased and family environment and parenting stress were improved significantly. These results suggest that this program is useful for its orginal goal. The parents evaluated also that children's total problem behaviors were decreased. Conclusion : These results suggest that the designed and performed group program in this study would be effective in facilitating ADHD children's emotional and interpersonal growth, and decreasing their parents stress. Finally they would have healthy interpersonal reationship.

삼풍사고 생존자들에서의 급성 외상후스트레스장애 : 발생빈도, 예측인자, 증상 변화에 대한 예비적 연구 A Preliminary Study on Incidence, Predictors and Pattern of Symptom Changes

김승태,김병로,홍경수,정유숙,유범희,김도관 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.3

목적 : 삼풍 백화점 붕괴 사고로 대단위 스트레스에 노출된 생존자들에서 급성 외상후스트레스장애(PTSD)의 발생빈도를 조사하고, 증상 발현에 대한 예측인자와 시간경과에 따른 증상 변화의 양상을 살펴보기 위하여 전향적 임상연구를 시행하였다. 방법 : 생존자 32명을 사고 후 1개월(1차 평가), 3개월(2차 평가) 경과 시점에, 한글 번역판 PTSD-I(DSM-III-R),을 사용하여 PTSD의 진단과 증상 정도를, Hamiltons Anxiety Scale(HAS)과 Hamiltons Depression Scale(HDS)을 사용하여 불안과 우울 증상의 정도를 평가하였다. PTSD 증상 심각도에 대한 예측인자는 단계적 선택 방법을 거친 다중회귀분석을, PTSD 증상의 변화는 paired t-test를 통해 살펴보았다. 결과 : 사고 발생 후 3개월 동안의 급성 PTSD 발생빈도는 완전한(true) PTSD가 41%, 부분성(partial) PTSD가 48%였다. 1차 평가시 HDS 점수가 PTSD-I 점수에 유의하게 기여하였고 동반자 사명여부는 HDS 점수와 부분적으로 관련되어 있었다. 2차 평가시에는 의식상실 유무가 PTSD-I, HDS, HAS 점수에 유의하게 기여하였다. 1, 2차 평가 기간 동안 PTSD-I 전체 점수는 변화가 거의 없었지만 재경험, 과각성 증상군 점수는 회피 증상군에 비해 유의하지는 않으나 상대적으로 감소하는 경향을 보였다. 결론 : 삼풍 사고 후 급성 PTSD의 발생빈도는 매우 높았고 사고 당시 동반자의 사망, 우울증의 정도, 의식상실 경험등이 생존자의 급성기 PTSD 증상 정도에 영향을 미치고 있었다. PTSD의 회피 증상은 재경험, 과각성등의 증상들에 비해 시간 경과에 따른 변화가 적은 경향이 있었다. Objective : This is a prospective clinical study on survivors of the collapse accident of a major department store building occurred in Seoul in June 1995 to investigate the incidence of acute PTSD, to identify risk factors affecting the severity of PTSD symptoms, and to evaluate the pattern of symptom changes over time. Method : Thirty-two victims were interviewed with modified Korean version of the PTSD-I(DSM-III-R) to determine the severity of symptoms and diagnosis of PTSD. Degrees of anxiety and depression were measured with Hamilton's Anxiety Scale(HAS) and Depression Scales(HDS) respectively. Subjects were assessed in series at one month(time point 1) and three month(time point 2) from the time the accident occurred. Results : The incidence of PTSD in the subjects over the 3 months was 41% using by full criteria and 48% by partial criteria. Regression analysis at the time point 1, the HDS score, which was partially related with death of accompanied persons(friends/relatives/colleagues), contributed significantly to the PTSD-I variances. At the time point 2, loss of consciousness contributed significantly to the variance of the PTSD-I, HDS and HAS scores. Between time point 1 and time point 2, the overall severity of PTSD symptoms for all the subjects has remained almost unchanged. However, re-experience and hyperarousal symptoms were improved almost unchanged. However, re-experience and hyperarousal symptoms were improved in comparison with avoidance symptoms, although not statistically significant. Conclusions : This study results show a high risk of developing PTSD and partial PTSD among the building collapse victims. The death of accompanied person, severity of depression and loss of consciousness are all regarded as major factors affecting the severity of PTSD. Of PTSD symptom clusters, avoidance symptoms are likely to be less changeable than re-experience and hyperarousal symptoms over time.

인터넷 중독 성향을 보이는 청소년들에서의 기질성격 특성

이문수,홍성도,정유숙 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.1

Objectives : Recent studies have focused on characteristics of adolescents who use internet addictively. Due to many ambi-guides in the definitions of internet addiction, it is hard to find a tool for diagnosing internet addiction. In this study, we attempt to identify the temperamental characteristics of adolescents who have addictive internet using patterns by administering a newly developed internet addiction scale based on a psychometric technique and temperament and character inventory (TCI) based on Cloninger's psychobiological model. Methods : Participants were 566 high school students. 478 students were recruited from high schools, and 88 were selected from internet cafes. We applied the internet addiction scale and TCI. All the students were divided into 3 groups (high risk user group, Potential risk user group and normal user group) according to the results of the internet addiction scale. TCI scores were compared and analyzed according to the participants' characteristics. Results : There were significant differences in the distribution of internet user group according to gender. Boys had higher percentage of high risk and potential risk users than girls. When each TCI score was compared according to gender, girls showed significantly higher harm avoidance, reward dependence, cooperativeness scale scores and lower persistence, self-transcendence scale scores than boys. TCI scores were compared among the internet addiction risk user groups. Risky internet users showed lower scores in reward dependence, self-directness and cooperativeness dimensions than normal internet users. Conclusion : There was a gender difference in internet addiction hsk in this study. These results suggest that adolescents who use internet addictively also have higher tendency of problematic social and interpersonal relationship. These tendencies need to be considered as one of the important aspects of internet addiction. This study shows that assessment of temperament and character in adolescents who have problems related to the internet may be needed for understanding their addiction behaviors and underlying psychopathologies.

電氣工學敎育의 發展方向에 關한 硏究

李鎭局,徐相壽,朴魯峰,李忠鎬,劉鍾哲,金洪奎,趙武濟,韓運東,池平植 충주대 2003 産業科學論文集 Vol.11 No.-

In this paper, we discuss actual conditions for running school of electrical and electronic engineering in domestic universities. Also, we catch hold of industrial circles's demands in electrical engineering education and analyze questionary results according to goes into effect school of electrical and electronic & information engineering in major of electrical and electronec engineering's students. Conclusively, we present suitable model in electrical engineering by correction of problems.

성인 급성 림프구성백혈병 고위험군에서 일차관해시 동종 및 자가 조혈모세포이식의 성적 비교 : 단일기관 치료경험 A Single Center Experience

이석,민우성,민창기,김동욱,이종욱,김유진,박은정,박윤희,김춘추 대한조혈모세포이식학회 2000 대한조혈모세포이식학회지 Vol.5 No.2

배경:성인 ALL에서 동종 조혈모세포이식은 전처치요법 및 이식편대백혈병 효과에 의한 효과적인 백혈병세포의 제거가 가능하다는 측면에서 활발히 시행되고 있으나 자가 조혈모세포이식과 화학요법과의 비교 연구에서는 대상환자의 다양성 등으로 인하여 상이한 결과가 보고되었다. 그러나 최근 진단당시 환자의 임상적·세포생물학적 특성 및 관해유도요법 후의 백혈병세포의 제거 속도 등을 기준으로 한 위험인자가 정의되면서 이를 근간으로 위험도에 따른 관해 후 치료방침의 결정이 타당성 있는 접근방법으로 제시되고 있고, 특히 고위험군에서의 동종 조혈모세포이식의 역할이 강조되고 있다. 방법: 성인 ALL 고위험군에서 일차 완전관해시 동종 조혈모세포이식의 역할을 규명하기 위해 최근 5년간 가톨릭의대 조혈모세포이식센터에서 ALL로 진단 후 일차 완전관해 상태에서 동종 및 자가 조혈모세포이식을 시행받고 임상적 특성과 세포면역학적 특성 및 세포유전학적 검사결과가 모두 확인 가능하였던 환자 중 고위험군에 해당된 50례를 대상으로 후향적 분석을 시행하였다. 고위험군은 진단시 연령이 30세 이상인 경우, 백혈구수가 30,000/μL 이상인 경우, 관해유도기간이 30일 이상 소요된 경우, Ph 혹은 t(4;11)이 동반된 경우 중 하나 이상의 인자를 갖고 있는 경우로 정의하였다. 결과: 대상환자의 중앙연령은 30세(15~43세)이었고, 남녀 비는 27:23이었다. FAB 분류상 L1 29례(58.0%), L2 21례(42.0%)였으며, precursor B-lineage 항원이 양성인 경우는 36례(72.0%), T-세포 항원이 양성인 경우는 9례(18.0%), 골수구계 항원이 동시에 발현된 경우는 5례(10.0%)였다. 세포유전학적 검사상 23례(46.0%)에서 불량한 염색체유형 [Ph 19례, t(4;11) 4례]이 동반되었다. 전체 환자 중 31례에서 동종 조혈모세포이식을 시행하였으며, 19례에서는 자가 조혈모세포이식이 시행되었다. 동종 및 자가 조혈모세포이식 환자군간의 임상적 특성은 양군간의 유의한 차이가 없었다. 대상환자의 중앙 추적관찰기간은 27개월(7~72개월)이었고, 전체 환자의 2년 무병생존율 및 전체생존율은 각각 59.0±7.6%, 68.2±7.1%이었다. 조혈모세포이식에 따른 치료성적을 비교한 결과 전체생존율은 동종 조혈모세포이식군 71.4±8.6%, 자가 조혈모세포이식군 62.7±12.4%로 양군간의 유의한 차이가 없었던 반면, 재발율은 동종 조혈모세포이식군에서 유의하게 낮은 빈도를 보였으며(25.8% vs 52.6%, P=0.05), 무병생존율에 있어서도 각각 70.6±9.0%, 42.1±12.2%로 동종 조혈모세포이식군에서 보다 높은 경향을 보였다(P=0.07). 이식 후 생존율에 영향을 주는 위험인자를 분석한 결과, 진단시 연령, 백혈구수, 관해유도기간에 따른 차이는 관찰되지 않았다. 다만 Ph 혹은 t(4;11)이 동반된 경우에서 무병생존율이 동종(28.5±16.0% vs 94.4±5.4%, P=0.0002) 및 자가 조혈모세포이식군(18.1±11.6% vs 80.0±17.8%, P=0.0046) 모두에서 유의하게 감소되었다. 결론: 본 연구를 통하여 일차관해시 조혈모세포이식을 시행받은 고위험군 성인 ALL에서는 관해 후 치료법으로써 동종 조혈모세포이식이 우선적으로 고려될 수 있는 치료법임을 확인할 수 있었다. 이는 추후 국내에서도 보다 장기간의 추적관찰을 통한 전향적 임상연구를 시행하여 보다 정립된 관해 후 치료방침의 결정 필요성을 제시하였다는 측면에서 임상적 의의가 있을 것으로 사료된다. Background:Optimal postremission therapy remains controversial in adult patients with acute lymphoblastic leukemia (ALL). In this study, we compared allogeneic bone marrow transplantation (alloBMT) with autologous peripheral blood stem cell transplantation (autoPBSCT) using the result of the human leukocyte antigen typing (HLA). Methods:Patients were eligible if they were in first remission (CR1) and had either: adverse cytogenetics [Philadelphia chromosome (Ph), t(4;11)], age >30 years, required more than 1 induction course to achieve remission (time-to-CR1 >30 days) or presenting WBC >30,000/μL. From July 1994 to June 1999, 50 consecutive adult patients with high-risk ALL underwent HLA-matched alloBMT (n=31) or autoPBSCT (n=19) at the Catholic Hemopoietic Stem Cell Transplantation Center. Results:There were 27 males and 23 females with median age 30 (range, 15~43) years. The distribution of phenotype was as follows: L1 (n=29), L2 (n=21), precursor B (n=36), T (n=9), myeloid marker coexpression (n=5). Adverse cytogenetic abnormalities at diagnosis were shown in 23 (46.0%) cases. All pretransplant characteristics were well balanced between these two groups. Most patients were treated with total body irradiation containing regimen as part of the conditioning. With a median follow-up of 27 months in both groups, disease-free survival (DFS) and overall survival probabilities at 2 years were 59.0±7.6% and 68.2±7.1%, respectively. The relapse rates were significantly different between alloBMT and autoPBSCT groups (25.8% vs 52.6%, P=0.05). There was no significant difference in overall survival between the two groups. However, alloBMT had a trend toward better DFS (70.6±9.0% vs 42.1±12.2%, P=0.07). None of the pretransplant characteristics significantly affected outcome after transplantation, except adverse cytogenetics. Prognosis of ALL with Ph or t(4;11) was significantly poorer than that of the remaining high-risk ALL patients (P<0.01). Conclusion: We conclude that alloBMT appears to be more effective than autoPBSCT in prolonging initial CR for high-risk ALL patients. Prospective studies addressing additional clinical variables are needed to guide clinical decision making about transplant choices for adult patients with ALL. New therapeutic strategies for the management of ALL with adverse cytogenetics will be also required.