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한국인 및 중국 한족 정신분열병 환자의 5-HT2A 수용체 유전자 -1438A/G 다형성
이장호,이광철,이승부,오용인,최영근,조아랑,정주호,장환일 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.1
Objectives : The purpose of the present study was to investigate the association between -1438A/G polymorphism of 5-HT2A receptor gene and schizophrenia in Korean and Han Chinese population. Methods : A sample of 184 Korean patients with schizophrenia and 96 Korean healthy normal controls and 96 Han Chinese patients with schizophrenia and 96 Han-Chinese healthy normal controls were genotyped for a single nucleotide polymorphism with in 5-HT2A receptor gene (promoter region, A-1438G) by Msp I Resthction Fragment Length Polymorphism (RFLP). Results : There was no difference in allelic frequencies and genotype frequencies of -1438A/G polymorphism between Korean schizophrenics and controls (p=0.13) and Han Chinese schizophrenics and controls (p=0.40). Also, -1438A/G Poly-morphism did not show ethnical difference between Korean and Han Chinese controls. The Scale for the Assessment of Negative Symptoms (SANS) scores showed no significant differences between genotypes of -1438A/G polymorphism in both of Korean and Han Chinese schizophrenics. Conclusion : These results suggest that -1438A/G polymorphism of the 5-HT2A receptor gene is not causally related to the development of schizophrenia in Korean and Han Chinese population, and there no ethnic difference between Korean and Han Chinese population.
기획논문 : 중국 서부지역의 부상과 한류 콘텐츠 수출 가능성 고찰 -도시화 과정 중 도시 활성화를 중심으로-
( Yong Sheng Zhao ) 한국문명학회 2013 문명연지 Vol.14 No.2
China have been attracting world’s attention with its rapid economic growth after reform and opening in 1978. Recent years, however, with change of domestic and foreign environment such as inflation of wages and American and European financial crises, the growth is showing signs of slowing down compare to the past. Because of this circumstance, Chinese government is gradually changing its economic growth method from Export-Led style to Urbanization, Expansion of Domestic Demand, Industrial Structure Acceleration and Expansion of Opening Policy-led style. Among these policies, it is expected that Urbanization can lead Chinese economic growth for considerable period of time. As of the urbanization is being progressed in China, this study have considered possibility of cultural export of Korean wave contents which can raise values of Chinese cities, especially for those of western area.
IN SITU UNZIPPING OF CARBON NANOTUBES TO FORM GRAPHENE NANORIBBONS
YONG-SHENG ZHOU,PAN JIN,TENG GUO,YING-CHUN ZHU,GAO-HUI DU,BING-SHE XU 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.1
We report the one step facile synthesis of graphene nanoribbons (GNRs) by unzipping carbonnanotubes (CNTs) from glucose (C 6 H 12 O 6 ) precursor, using a simple chemical vapor depositionmethod. Some nanotubes are partially cut resulting in a GNR – CNT hybrid whereas others arefully cut to form GNRs. The average length of GNRs achieved by this method is typically in therange of 1 – 10 ? m. The formation of GNRs is ascribed to the in situ oxygen-driven unzipping ofCNTs. The process is free from aggressive oxidants and utilizes the in situ unzipping. Thismethod o®ers an alternative approach for making GNRs, compared to previously used techniquesto synthesize GNRs.
Yong-Sheng Lian,Jun-Yi Sun,Jiao Dong,Zhou-Lian Zheng,Zhi-Xin Yang 국제구조공학회 2019 Structural Engineering and Mechanics, An Int'l Jou Vol.69 No.6
In this study, the problem of axisymmetric deformation of prestressed Föppl-Hencky membrane under constrained deflecting was analytically solved and its closed-form solution was presented. The small-rotation-angle assumption usually adopted in membrane problems was given up, and the initial stress in membrane was taken into account. Consequently, this closed-form solution has higher calculation accuracy and can be applied for a wider range in comparison with the existing approximate solution. The presented numerical examples demonstrate the validity of the closed-form solution, and show the errors of the contact radius, profile and radial stress of membrane in the existing approximate solution brought by the small-rotation-angle assumption. Moreover, the influence of the initial stress on the contact radius is also discussed based on the numerical examples.
Energy Efficient Heterogeneous Cellular Networks
Yong Sheng Soh,Quek, T. Q. S.,Kountouris, M.,Hyundong Shin IEEE 2013 IEEE journal on selected areas in communications Vol.31 No.5
<P>With the exponential increase in mobile internet traffic driven by a new generation of wireless devices, future cellular networks face a great challenge to meet this overwhelming demand of network capacity. At the same time, the demand for higher data rates and the ever-increasing number of wireless users led to rapid increases in power consumption and operating cost of cellular networks. One potential solution to address these issues is to overlay small cell networks with macrocell networks as a means to provide higher network capacity and better coverage. However, the dense and random deployment of small cells and their uncoordinated operation raise important questions about the energy efficiency implications of such multi-tier networks. Another technique to improve energy efficiency in cellular networks is to introduce active/sleep (on/off) modes in macrocell base stations. In this paper, we investigate the design and the associated tradeoffs of energy efficient cellular networks through the deployment of sleeping strategies and small cells. Using a stochastic geometry based model, we derive the success probability and energy efficiency in homogeneous macrocell (single-tier) and heterogeneous K-tier wireless networks under different sleeping policies. In addition, we formulate the power consumption minimization and energy efficiency maximization problems, and determine the optimal operating regimes for macrocell base stations. Numerical results confirm the effectiveness of switching off base stations in homogeneous macrocell networks. Nevertheless, the gains in terms of energy efficiency depend on the type of sleeping strategy used. In addition, the deployment of small cells generally leads to higher energy efficiency but this gain saturates as the density of small cells increases. In a nutshell, our proposed framework provides an essential understanding on the deployment of future green heterogeneous networks.</P>
The elastoplastic formulation of polygonal element method based on triangular finite meshes
Yong-chang Cai,He-hua Zhu,Sheng-yong Guo 국제구조공학회 2008 Structural Engineering and Mechanics, An Int'l Jou Vol.30 No.1
A small strain and elastoplastic formulation of Polygonal Element Method (PEM) is developed for efficient analysis of elastoplastic solids. In this work, the polygonal elements are constructed based on traditional triangular finite meshes. The construction method of polygonal mesh can directly utilize the sophisticated triangularization algorithm and reduce the difficulty in generating polygonal elements. The Wachspress rational finite element basis function is used to construct the approximations of polygonal elements. The incremental variational form and a von Mises type model are used for non-linear elastoplastic analysis. Several small strain elastoplastic numerical examples are presented to verify the advantages and the accuracy of the numerical formulation.
( Yong-sheng Tian ),( Jing Xu ),( Lei-chen ),( Xiao-yan Fu ),( Ri-he Peng ),( Quan-hong Yao ) 한국미생물생명공학회(구 한국산업미생물학회) 2017 Journal of microbiology and biotechnology Vol.27 No.10
Thermostability is an important property of xylanase because high temperature is required for its applications, such as wood pulp bleaching, baking, and animal feedstuff processing. In this study, XynB from Thermobacillus composti, a moderately thermophilic gram-negative bacterium, was modified via site-directed mutagenesis (based on its 3D structure) to obtain thermostable xylanase, and the properties of this enzyme were analyzed. Results revealed that the half-life of xylanase at 65°C increased from 10 to 50 min after a disulfide bridge was introduced between the α-helix and its adjacent β-sheet at S98 and N145. Further mutation at the side of A153E named XynB-CE in the C-terminal of this α-helix enhanced the half-life of xylanase for 60 min at 65°C. Therefore, the mutant may be utilized for industrial applications.