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High Precision FE Modeling for Predicting Inner Polygon Defect of Hot Rolled Seamless Steel Tubes
Yong-Zheng Jiang,Yong-Zheng Jiang,Xiao-Ping Zhang,Kuan-Fang He,Guan-Fu Bin 대한토목학회 2018 KSCE Journal of Civil Engineering Vol.22 No.11
A high precision FE model is the key basis for cause analysis and overcoming of inner polygon defect of hot rolled seamless steel tubes. In this paper, the viscoelastic-plastic FEM is adopted in order to develop a high precision FE model for predicting the defect of inner polygon. Mechanical properties of tube material under rolling environment is obtained through five sets of high temperature compression tests, thus the viscoelastic-plastic constitutive equation of tube material is regressed and agrees with the tests results. Heat transfer boundary conditions, roll constant speed and contact friction boundary conditions are applied simultaneously on the FE model and thermo-mechanical coupled explicit algorithm is adopted for solution. The precision of the FE model is verified through industry experiments. Results shows the simulated inner wall shape is in good accordance with the experiment results, and the friction force, stress, strain and temperature distribution in the deformation zone are also discussed. It can be concluded that the viscoelastic-plastic FE model is of high precision and can be applied for better analysis of the hot rolling results.
Yong-hong Miao,Ping-ping Zuo,Jie Yin,Shoaib Ahmed,Guo-long Bai,Jian-fei Lu 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.9
This paper presents an improved method for predicting the bearing capacity of single jacked pile based on piezocone penetration test (CPTu) data which contain tip resistance (qt), side friction ( fs) and excess dynamic pore water pressure (u2). Firstly, the average value of qt was determined to calculate the pile unit base resistance according to the influence zone of the logarithmic spiral concerning the effect of soil types. Secondly, fs and u2 were used to calculate the pile unit shaft resistance considering the effect of friction fatigue. The pile jacking force was obtained in terms of unit base resistance and unit shaft resistance. The ultimate bearing capacity was finally determined using pile jacking force multiplied by a force ratio denoted as Rf. The ultimate bearing capacities calculated for two case projects show a good agreement with the measured results, which indicates that the proposed method is feasible and effective. Reliability assessment was carried out on the proposed method and other five estimation methods with respect to the reliability index obtained by advanced first-order second-moment (AFOSM) method. Comparison result showed that the method proposed in this study has a higher reliability index over other five existing methods. Therefore, the proposed method can be used as a reliable alternative to predict the bearing capacity in the engineering practice of jacked pile foundation.
Yong, Jian-Ping,Aisa, Haji Akber Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.4
To improve the biological activities of rupestonic acid, 21 new rupestonic acid fatty ester derivatives (2a-2h) and aromatic ester derivatives (2i-2u) were synthesized and preliminarily evaluated for their anti-influenza activity in vitro by the national center for drug screening of China, using the Oseltamivir and Ribavirin as reference drugs. The results showed that 2l ($IC_{50}=0.5{\mu}mol/L$) exhibited potent anti-influenza $A_3$ viral activity among the synthesized compounds and was 10-fold more potent than that of the reference drug Oseltamivir ($IC_{50}=5.1{\mu}mol/L$).
Yong, Jian-Ping,Lv, Qiao-Ying,Aisa, Haji Akber Korean Chemical Society 2009 Bulletin of the Korean Chemical Society Vol.30 No.2
19 Aromatic ring and L-amino acid ester contained rupestonic acid amide derivatives 2a~2l, 3a~3g were synthesized and preliminarily evaluated in vitro against influenza virus $A_3$,B and herpes simplex virus type 1 (HSV-1), 2(HSV-2) by the national center for drug screening of China. The rusults showed that 2i possessed the highest inhibition against both influenza virus $A_3\;(TC_{50}\;=\;120.6\;{\mu}mol/L,\;IC_{50}=\;19.2\;{\mu}$mol/L, SI = 6.3) and B (T$C_{50}\;=\;120.6\;{\mu}mol/L,\;IC_{50}=\;29.9\;{\mu}$mol/L, SI = 4.0); 2g was more active against influenza $A_3$ virus at very low cytotoxicity ($TC_{50}\;>\;2092.1\;{\mu}mol/L,\;IC_{50}=\;143.7\;{\mu}mol/L,$ SI > 14.6) than the parent compound; Compounds 2b, 2c, 2f showed higher activities both against HSV-1 and HSV-2 than that of the parent compound, and 2f was the most potent inhibitor of HSV-1 ($TC_{50}\;=\;200.0\;{\mu}mol/L,\;IC_{50}\;=\;11.3\;{\mu}mol$/L, SI = 17.7 ) and HSV-2 ($TC_{50}\;=\;200.0\;{\mu}mol/L,\;IC_{50}\;=\;20.7\;{\mu}mol$/L , SI = 9.7).
( Yong Ping Zhang ),( Yi Li Zhang ),( Yan Hong Zhou ),( Jing Quan Yu ) 한국식물학회 2007 Journal of Plant Biology Vol.50 No.5
To investigate their response to changes in substrate temperatures, the roots from six species of cucurbit plants were exposed to 14℃, 24℃, or 34℃, while their aerial portions were maintained at natural ambient temperatures (23℃ to 33℃). These species could be classified into three groups based on their stress response: Group A, Cucurbita ficifolia and C. maxima, heatsensitive but cold-tolerant; Group B, Cucumis sativus and C. melo, heat- and cold-sensitive; and Group C, Luffa cylindrica and Benincasa hispida, heat-tolerant but cold-sensitive. The highest growth rates and lowest contents of malondialdehyde (MDA) for plants in Groups A, B, and C were achieved at temperatures of 14℃, 24℃, and 24℃ to 34℃, respectively. Superoxide dismutase (SOD) activity was lowest in the roots exposed to optimal growth temperatures while activities of catalase (CAT), ascorbate peroxidase (APX), and guaiacol peroxidase (G-POD) operated coordinately in a complicated manner to prevent the accumulation of reactive oxygen species (ROS) in the root cells. Moreover, all plants, regardless of species, responded to unfavorable temperatures by increasing their synthesis of ascorbate and glutathione as well as by reducing the redox ratio of those two important antioxidants.
A Single Chord Localization Algorithm for Wireless Sensor Networks
Yong-Luo Shen,Yuan Zhang,Yu-Ping Hu,Jun Zhang 보안공학연구지원센터 2015 International Journal of Grid and Distributed Comp Vol.8 No.1
This paper presents a novel range-free single chord localization algorithm with low energy consumption and high accuracy for wireless sensor networks. A mobile anchor node and a mobile reference node are employed to periodically broadcast beacon messages and reference messages, respectively. Each sensor node is equipped with a received signal strength indicator for comparing the signal strength. By using the edge function and the result of comparing signal strength, each sensor node only needs one chord on the communication circle for localization. Compared with previous approaches that require multiple chords, less beacon messages are required by the sensor nodes. In the proposed algorithm, the localization error mainly depends on the move distance interval. However, for the other approaches, large localization errors can be observed according to the angle between chords which may descend the localization accuracy dramatically. Analysis results indicate that the proposed algorithm is superior to other approaches in energy consumption and localization accuracy.
Yong-Ping Chen,Feng-Bin Lu,Da-Zhi Chen,Lu Chen,En-De Hu,Jin-Lu Wu,Hui Li,Yue-Wen Gong,Zhuo Lin,Xiao-Dong Wang,Ji Li,Xiao-Ya Jin,Lan-Man Xu 한국분자세포생물학회 2019 Molecules and cells Vol.42 No.12
MicroRNA-223-3p (miR-223-3p) is one of the potential microRNAs that have been shown to alleviate inflammatory responses in pre-clinical investigations and is highly encased in exosomes derived from bone mesenchymal stem cells (MSC-exosomes). MSC-exosomes are able to function as carriers to deliver microRNAs into cells. Autoimmune hepatitis is one of the challenging liver diseases with no effective treatment other than steroid hormones. Here, we examined whether MSC-exosomes can transfer miR-223-3p to treat autoimmune hepatitis in an experimental model. We found that MSC-exosomes were successfully incorporated with miR-223-3p and delivered miR-223-3p into macrophages. Moreover, there was no toxic effect of exosomes on the macrophages. Furthermore, treatments of either exosomes or exosomes with miR-223-3p successfully attenuated inflammatory responses in the liver of autoimmune hepatitis and inflammatory cytokine release in both the liver and macrophages. The mechanism may be related to the regulation of miR-223-3p level and STAT3 expression in the liver and macrophages. These results suggest that MSC-exosomes can be used to deliver miR-223-3p for the treatment of autoimmune hepatitis.
Ping-ping Zhou,Hua-chun Wu,Yong-Mei Xia 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.33 No.-
Polymers have been used to modulate mechanical strengths and water absorption of construction ormodeling materials as like gypsum. To understand the structure–performance relationship of polymersin hydration and properties of gypsum plaster, several designed carboxyl polyether sulfonates wereinvestigated with comparison of some commercial polymers. It is found that bending strength of thehardened b-hemihydrate plaster is inversely proportional to number of carboxyl groups in the polymerthat retards hydration. The mechanical strengths enhancement is coincident with acceleration of initialhydration, while decrease of mechanical strengths happened with retard of the hydration.
Insect-specific microRNA involved in the development of the silkworm Bombyx mori
Yong Zhang,Xue Zhou,Xie Ge,Jiang-Hao Jiang,Mu-Wang Li,Shi-Hai Jia,Xiao-Nan Yang,Yun-Chao Kan,Xue-Xia Miao,Guo-Ping Zhao,Fei Li,Yong-Ping Huang 한국응용곤충학회 2009 한국응용곤충학회 학술대회논문집 Vol.2009 No.10
MicroRNAs (miRNAs) are endogenous non-coding genes that participate in post-transcription regulation by either degrading mRNA or blocking its translation. It is considered to be very important in regulating insect development and metamorphosis. Insects are the largest group of animals and are extremely valuable in biological and agriculture research. Insects are also important pests to human health and agriculture, and efforts are necessary protect both humans and plants from disease and damage. Despite their importance, insects lag behind mammals, nematodes, and plants in miRNA research. At present, only 279 insect miRNAs have been identified from Drosophila melanogaster, Anopheles gambiae, Apis mellifera, Bombyx mori, and D. pseudoobscura in miRBase, and most of these miRNAs were computationally predicted without experimental validation. Functional analysis of insect miRNAs has only been conducted in D. melanogaster.
Regulation of meilingmycin in Streptomyces nanchangensis: Effect of ammonium ion
Ying-ping Zhuang,Yong Wang,Ping Wang,Ju Chu,Si-liang Zhang 한국화학공학회 2010 Korean Journal of Chemical Engineering Vol.27 No.3
Effects of different ammonium sulfate concentrations on meilingmycin biosynthesis were studied in this research. The results show that a lower concentration of ammonium ions stimulates the biosynthesis of meilingmycin,while a concentration higher than 5mmol/L inhibits the mycelial growth and the biosynthesis of the products. However,increased sugar consumption rate with the elevated concentration of ammonium sulfate was observed during the fermentation process. On this basis, six enzymes, which are responsible for the meilingmycin biosynthesis and the glucose metabolism, were measured and analyzed during the bioprocess. The results suggest that glucose-6-phosphate dehydrogenase, citrate synthase, succinate dehydrogenase and fatty acid synthase are stimulated by higher concentration of ammonium ions, while valine dehydrogenase and methylmalonyl-CoA carboxyltransferase are inhibited. From the results it follows that the precursor supply was restricted with the higher concentration of ammonium ions, which results in the lower production of meilingmycin. Thus, the strategy of maintaining a low level of FAS activity is a critical factor for high yield of meilingmycin.