Relationships between Islet-Specific Autoantibody Titers and the Clinical Characteristics of Patients with Diabetes Mellitus

Yiqian Zhang,Tong Yin,Xinlei Wang,Rongping Zhang,Jie Yuan,Yi Sun,Jing Zong,Shiwei Cui,Yunjuan Gu 대한당뇨병학회 2021 Diabetes and Metabolism Journal Vol.45 No.3

Background: Dysimmunity plays a key role in diabetes, especially type 1 diabetes mellitus. Islet-specific autoantibodies (ISAs) have been used as diagnostic markers for different phenotypic classifications of diabetes. This study was aimed to explore the relationships between ISA titers and the clinical characteristics of diabetic patients. Methods: A total of 509 diabetic patients admitted to Department of Endocrinology and Metabolism at the Affiliated Hospital of Nantong University were recruited. Anthropometric parameters, serum biochemical index, glycosylated hemoglobin, urinary microalbumin/creatinine ratio, ISAs, fat mass, and islet β-cell function were measured. Multiple linear regression analysis was performed to identify relationships between ISA titers and clinical characteristics. Results: Compared with autoantibody negative group, blood pressure, weight, total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), visceral fat mass, fasting C-peptide (FCP), 120 minutes C-peptide (120minCP) and area under C-peptide curve (AUCCP) of patients in either autoantibody positive or glutamate decarboxylase antibody (GADA) positive group were lower. Body mass index (BMI), waist circumference, triglycerides (TGs), body fat mass of patients in either autoantibody positive group were lower than autoantibody negative group. GADA titer negatively correlated with TC, LDL-C, FCP, 120minCP, and AUCCP. The islet cell antibody and insulin autoantibody titers both negatively correlated with body weight, BMI, TC, TG, and LDL-C. After adjusting confounders, multiple linear regression analysis showed that LDL-C and FCP negatively correlated with GADA titer. Conclusion: Diabetic patients with a high ISA titer, especially GADA titer, have worse islet β-cell function, but less abdominal obesity and fewer features of the metabolic syndrome.

Investigating Similar and Dissimilar Productions and Perceptions of Mid Front Vowels in Taizhou Wu

Yiqian Wang,이용철 한국중원언어학회 2023 언어학연구 Vol.- No.68

To investigate whether particular vowels in Taizhou Wu have overlapping distributions in vowel clusters, this study conducted production and perception experiments. For the production experiment, 55 speakers born in the 1960s and 2000s were recruited, with 11 speakers in each 10-year age group, and these speakers read aloud the target vowels in a carrier phrase. The results revealed that the vowels [e] and [Ø] had overlapping distributions, mainly in terms of F1. Therefore, the vowel [Ø] was frequently misidentified as the vowel [e] in perception, particularly when the roundedness feature was missing. Despite some acoustic similarities between the vowels [Ø] and [ɛ] in terms of F2, listeners could still differentiate them based on a significant difference in F1. This study has two implications. First, the absence of roundedness in [Ø] can cause the vowel to be perceived as [e]. Second, a significant difference in one acoustic cue, such as F1, is necessary for distinct perception between the vowels [Ø] and [ɛ], despite acoustic similarities in F2.

부모와의 관계가 이중언어인식의 매개를 통해 다문화가족 아동의 자긍심에 미치는 영향

( Wang Yiqian ),이수진 ( Lee Sue-jin ),이정애 ( Lee Jung-ae ),정익중 ( Chung Ick-joong ) 한국학교사회복지학회 2017 학교사회복지 Vol.0 No.39

본 연구는 부모와의 관계가 다문화가족 아동의 자긍심에 영향을 미치는지, 그 관계에서 아동이 느끼는 이중언어 인식이 매개역할을 하는지 규명하고자 하였다. 이를 위해 <2015년 전국다문화 가족 실태조사>를 활용하였고, 9세부터 18세미만의 다문화 가족 총 2934명 아동을 대상으로 통계분석에 활용하였다. 분석 결과, 부모와의 관계가 긍정적일수록 다문화 가족 아동의 자긍심이 높아지는 것으로 나타났고, 이중언어인식은 부모와의 관계와 다문화가족 자긍심의 사이에서 부분 매개역할을 하였다. 중국, 베트남, 필리핀 3개의 국가에서 모두 매개효과가 나타났다. 이를 바탕으로 다문화가족 아동이 건강한 성인으로 성장할 수 있도록 사회복지 실천적·정책적 함의를 제언하였다. This study aims to investigate the effect of bilingual perception as a mediator by looking at relationship with parents effects the self-pride of multicultural family children. We used the data from “2015 multicultural family survey” and statistically analyzed 2934 children aged 9-18 years old from multicultural families. The finding shows the more positive the relationship with parent is, the higher the self-pride of multicultural family children is, and bilingual perception does partial mediation between the relationship with parent and the self-pride of multicultural family children. The mediation effect was found the three countries: China, Vietnam and the Philippine. Base on the finding of the study, we proposed social work practice and policy implication for the multicultural family children to grow up as healthy adults.

[BMIM]Cl-nAlCl3 ionic liquid-catalyzed redistribution reaction between methyltrichlorosilane and low-boiling residue to dimethyldichlorosilane

Aili Wang,Yiqian Jiang,Weiguang Chen,Yanjun Liu,Yutang Shen,Tingshun Jiang,Zhanao Wu,Hengbo Yin 한국공업화학회 2012 Journal of Industrial and Engineering Chemistry Vol.18 No.1

Methyltrichlorosilane and low-boiling residue from the synthesis of methylchlorosilanes via the direct reaction of silicon and methyl chloride were effectively converted to high-valued dimethyldichlorosilane catalyzed by 1-butyl-3-methylimidazolium chloroaluminate, [BMIM]Cl-nAlCl3, ionic liquid catalysts. The yield of dimethyldichlorosilane reached 69.1% when the redistribution reaction between methyltrichlorosilane and low-boiling residue was catalyzed by [BMIM]Cl-6AlCl3 at a reaction temperature of 150 8C for 300 min. The conversion of methyltrichlorosilane was 87.8%. And the conversions of tetramethylsilane, methylhydrodichlorosilane, and dimethylhydrochlorosilane present in low-boiling residue were ca. 100%, respectively. The ionic liquids could be recycled efficiently. This research provided an eco-friendly and economical route for the treatment of methyltrichlorosilane and low-boiling residue, which were the by-products in the direct synthesis of methylchlorosilanes. The possible reaction route was also discussed.

Polyelectrolyte Complex Formation between Cationic Fixing Agent and Dissolved Substances in Papermaking

Lijun Wang,Yiqian Zhang,Pedram Fatehi 한국펄프·종이공학회 2016 펄프.종이기술 Vol.48 No.6

Dissolved substances (DS) in papermaking suspension contribute a large portion of negativity to the total dissolved and colloidal substances (DCS). Compared to colloidal substances (CS), dissolved substances are clearly more difficult to be removed by fixing agents (FA). Formation of polyelectrolyte complexes (PECs) between fixing agents and dissolved substances plays a very important role in clarifying the mechanism of a fixing agent acting on DCS. This study, therefore, focused on the characteristics of PECs formed between fixing agents and dissolved substances. Three polyamines (PA) with different molecular weight and slight different charge density were synthesized and used as fixing agents, in four different kinds of water including, two kinds of DCS water separated from a same deinked pulp (DIP) but with different size and distribution of CS particles, and two kinds of DS water modeled by oxidized starch (OS) and hemicelluloses (HC). The formation of PEC in these systems and their corresponding characteristics were characterized using focused beam reflectance meter (FBRM), laser particle size analyzer (LPSA), turbidity meter, and charge detection. From the results, it is concluded that for a given DS component and a certain kind of fixing agent, the formation of DSfixing agent PECs highly depended on the molecular weight of the fixing agent and its dosage. A fixing agent with enough low molecular weight could form big but loose and dispersible DS-FA PECs, increasing its dosage would produce denser and smaller PECs; and a fixing agent with enough high molecular weight could directly form dense PECs, increasing its dosage increased the size of PECs. Depositing DS-FA PECs onto small CS particles also played an important role in forming new CS particles with larger sizes, and in this case, a fixing agent with higher molecular weight tended to produce more large particles.

Methylation of methyltrichlorosilane with methyl chloride over active metals and activated carbon

Yanjun Liu,Yiqian Jiang,Weiguang Chen,Yutang Shen,Yonghai Feng,Lingqin Shen,Aili Wang,Tingshun Jiang,Zhanao Wu 한국화학공학회 2011 Korean Journal of Chemical Engineering Vol.28 No.12

Gas phase methylation of methyltrichlorosilane with methyl chloride to high-valued dimethyldichlorosilane was carried out by using metallic aluminum as a chlorine acceptor in the co-presence of activated carbon, tin, and zinc. The addition of activated carbon in metallic aluminum significantly enhanced the methylation of methyltrichlorosilane,and dimethyldichlorosilane was dominantly produced. Activated carbon played a catalyst role in the methylation reaction. When active metals, such as tin and zinc, were added in the mixture of aluminum and activated carbon,the active metals and activated carbon synergistically catalyzed the methylation of methyltrichlorosilane with methyl chloride toward the formation of dimethyldichlorosilane.

Polyelectrolyte Complex Formation between Cationic Fixing Agent and Dissolved Substances in Papermaking

Lijun Wang,Yiqian Zhang,Pedram Fatehi 한국펄프·종이공학회 2016 한국펄프·종이공학회 학술발표논문집 Vol.2016 No.10

1. Formation of DS-fixing agent PEC highly depends on the DS components, fixing agent molecular weight and its dosage, as very different phenomena can be seen in this study for different DS components, for polyamines with different molecular weight, and for the same polyamine used at a different dosage. 2. For fixing agent with enough low molecular weight and at enough low dosage, it can form loose and dispersible DS-fixing agent PECs, and increasing its dosage will produce denser and smaller PECs; for fixing agent with enough high molecular weight, it can directly form dense DS-fixing agent PECs, and increasing its dosage mainly increases the size of PECs; for fixing agent with medium molecular weight, its behaves between the two cases described above. 3. Although hemicelluloses modeled DS water showed that a small part of PECs formed are detectable by FBRM, the performance of DCS water 2 used in this study showed that DS-fixing agent PECs alone are generally too small to be detected by FBRM. 4. Based on the performance of DCS water 1 and DCS used in this study, it can be concluded that small CS particles undetectable by FBRM can be the “seeds” for producing larger particles detectable by FBRM, either by agglomerating the small CS particles or by depositing DS-fixing agent PECs onto the small CS particles. For the formation of FBRM-detectable particles, the agglomeration of medium sized CS particles (between 125nm-470nm in this study), or deposition of DS-fixing agent PECs onto such particles, seems critical.

Catalytic chlorination of methylphenyldichlorosilane with gaseous chlorine to chlorinated methylphenyldichlorosilanes over Lewis acids

Yujun Fu,Hengbo Yin,Yiqian Jiang,Lingqin Shen,Yonghai Feng,Aili Wang 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.3

Methylchlorophenyldichlorosilane (MeClPhSiCl2) and methyldichlorophenyldichlorosilane (MeCl2Ph-SiCl2) were synthesized by the catalytic chlorination of methylphenyldichlorosilane (MePhSiCl2) withCl2 over Lewis acid catalysts. The catalytic activities of Lewis acid catalysts were in an order ofFeCl3 > SbCl5 > AlCl3 > SnCl4. However, FeCl3 also highly catalyzed the cleavage of chlorophenyl–siliconbond to form chlorobenzene. At a low mole ratio of SbCl5 to MePhSiCl2 of 1.4 × 10-5:0.45, the yield ofMeClPhSiCl2 was around 60% after reacting at 25–100 8C for 15–20 h. At a high mole ratio of1.4 × 10-4:0.45, the yield of MeCl2PhSiCl2 reached 44% after reacting at 80–100℃ for 20 h.

Nonlinear fatigue life prediction model based on material memory

Xu Xu,Qiwen Xue,Yiqian He 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.12

New nonlinear fatigue damage accumulation model is established on the basis of material memory theory and fatigue driving energy damage parameters to evaluate highcycle fatigue life under multilevel variable amplitude loading. The loading interaction factor is constructed on the basis of damage degree and then the model is modified to consider the effect of loading interaction on fatigue damage accumulation. The two proposed models are convenient for calculation and have only two parameters that can be easily identified through experiments. In accordance with the test data of aluminum alloy Al-2024-T42, titanium alloy Ti-6Al-4V, nodular cast iron GS61, Q235B welded joint, and hot-rolled 16Mn steel, the two models developed in this study have been verified to predict fatigue life effectively. For multilevel loading, the modified model achieves higher prediction accuracy and its results are closer to the actual test data compared with those of the other models.

One-Pot Synthesis of α-Fe2O3 Nanospindles as High-Performance Lithium-Ion Battery Anodes

Yanhua Ding,Bing Liu,Rongsheng Cai,Tuo Xin,Chen Li,Linhua Xia,Yiqian Wang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.2

Hematite nanospindles with a uniform size of ~270 nm in length and ~90 nm in width are prepared using a facile one-step hydrothermal method. Polyvinylpyrrolidone (PVP) serves as a structure-directing agent to control the primary morphology and aggregations. When evaluated as anode materials for lithium-ion batteries (LIBs), the electrode of sodium alginate (SA) binder exhibits a much better electrochemical performance than that with the polyvinylidene fluoride (PVDF) binder. Remarkably, the electrode using SA binder can deliver a high reversible specific capacity of 979mAh · g -1 after 50 cycles and prominent rate capability. The microstructural evolution of the nanospindles after the electrochemical cycling is investigated by scanning transmission electron microscopy (STEM). Our results may provide important mechanistic insights for the design of nanostructured anode materials for LIBs.