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        • KCI등재

          Routine calcitonin measurement in nodular thyroid disease management: is it worthwhile?

          Yigit,Turk,Ozer,Makay,Murat,Ozdemir,Gozde,Ertunc,Batuhan,Demir,Gokhan,Icoz,Mahir,Akyildiz,Mustafa,Yilmaz 대한외과학회 2017 Annals of Surgical Treatment and Research Vol.92 No.4

          Purpose: To evaluate the diagnostic accuracy of routine calcitonin measurement in patients with nodular thyroid disease. Methods: Consecutive patients with nodular thyroid disease (n = 640) were studied. Serum calcitonin levels were measured under basal conditions, and when basal values were between 10–100 pg/mL, testing was repeated after pentagastrin (PG) stimulation. Patients with previously diagnosed or familial medullary thyroid cancer (MTC) were excluded. Patients were operated on when basal or stimulated calcitonin >100 pg/mL or when other surgical indications were present. Results: Four cases of MTC were identified. MTC was diagnosed in 75% of patients with basal calcitonin >100 pg/mL. One out of 11 patients with basal calcitonin between 10–100 pg/mL was diagnosed with MTC. PG stimulation resulted in elevation in 4 cases, where 1 case was diagnosed with MTC. Positive predictive value for basal calcitonin levels in the preoperative diagnosis of MTC was 5% for values between 10–100 pg/mL and 100% for values >100 pg/mL. Possible reasons for false positivity were papillary thyroid cancer in 17%, renal insufficiency in 8.3%, Hashimoto thyroiditis in 17% and β-blocker use in 33%. Positive predictive value for the PG test (>100 pg/mL) was 25% in the entire series. The cost of adding calcitonin measurement (±PG stimulation) to the preoperative work-up, resulted in €912.68 per MTC patient to detect the disease. Conclusion: Basal calcitonin measurement together with PG stimulation in cases of basal calcitonin >10 pg/mL detects MTC in 0.62% of patients with nodular thyroid disease.

        • SCIESCOPUSKCI등재

          Effect of β-Mannanase and α-Galactosidase Supplementation to Soybean Meal Based Diets on Growth, Feed Efficiency and Nutrient Digestibility of Rainbow Trout, Oncorhynchus mykiss (Walbaum)

          Yigit,,Nalan,Ozgur,Koca,,Seval,Bahadir,Isil,,Behire,Diler,,Ibrahim Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.5

          A 12-week feeding trial was conducted with 87 g rainbow trout to evaluate the effects on growth performances, feed efficiency and nutrient digestibility of adding ${\beta}$-mannanase and ${\alpha}$-galactosidase enzymes, solely or in combination. Seven diets were prepared by adding ${\beta}$-mannanase, ${\alpha}$-galactosidase and mixed enzyme at two different levels (1 g/kg and 2 g/kg) to control diet (without enzyme) including soybean meal. Mixed enzymes (1 g/kg, 2 g/kg) were prepared by adding ${\beta}$-mannanase and ${\alpha}$-galactosidase at the same doses (0.5+0.5 g/kg and 1+1 g/kg). At the end of the experiment, addition of ${\beta}$-mannanase, ${\alpha}$-galactosidase and mixed enzyme to diet containing 44% soybean meal had no significant effects on growth performance and gain:feed (p>0.05). In addition, adding ${\beta}$-mannanase, ${\alpha}$-galactosidase and mixed enzyme in different rations to trout diets had no affect on nutrient digestibility and body composition (p>0.05).

        • SCIESCOPUSKCI등재

          Model-based predictions for nuclear excitation functions of neutron-induced reactions on <sup>64,66-68</sup>Zn targets

          Yigit,,M.,Kara,,A. Korean Nuclear Society 2017 Nuclear Engineering and Technology Vol.49 No.5

          In this paper, nuclear data for cross sections of the $^{64}Zn(n,2n)^{63}Zn$, $^{64}Zn(n,3n)^{62}Zn$, $^{64}Zn(n,p)^{64}Cu$, $^{66}Zn(n,2n)^{65}Zn$, $^{66}Zn(n,p)^{66}Cu$, $^{67}Zn(n,p)^{67}Cu$, $^{68}Zn(n,p)^{68}Cu$, and $^{68}Zn(n,{\alpha})^{65}Ni$ reactions were studied for neutron energies up to 40 MeV. In the nuclear model calculations, TALYS 1.6, ALICE/ASH, and EMPIRE 3.2 codes were used. Furthermore, the nuclear data for the (n,2n) and (n,p) reaction channels were also calculated using various cross-section systematics at energies around 14-15 MeV. The code calculations were analyzed and obtained using the different level densities in the exciton model and the geometry-dependent hybrid model. The results obtained from the excitation function calculations are discussed and compared with literature experimental data, ENDF/B-VII.1, and the TENDL-2015 evaluated data.

        • SCIESCOPUSKCI등재

          Theoretical study of cross sections of proton-induced reactions on cobalt

          Yigit,,Mustafa Korean Nuclear Society 2018 Nuclear Engineering and Technology Vol.50 No.3

          Nuclear fusion may be among the strongest sustainable ways to replace fossil fuels because it does not contribute to acid rain or global warming. In this context, activated cobalt materials in corrosion products for fusion energy are significant in determination of dose levels during maintenance after a coolant leak in a nuclear fusion reactor. Therefore, cross-section studies on cobalt material are very important for fusion reactor design. In this article, the excitation functions of some nuclear reaction channels induced by proton particles on $^{59}Co$ structural material were predicted using different models. The nuclear level densities were calculated using different choices of available level density models in ALICE/ASH code. Finally, the newly calculated cross sections for the investigated nuclear reactions are compared with the experimental values and TENDL data based on TALYS nuclear code.

        • SCIESCOPUSKCI등재

          Study on (n,p) reactions of <sup>58,60,61,62,64</sup>Ni using new developed empirical formulas

          Yigit,,Mustafa Korean Nuclear Society 2020 Nuclear Engineering and Technology Vol.52 No.4

          Nuclear fusion seems to be a good choice of energy source in the future. Nickel is one of the crucial structural materials for fusion devices. In this work, the cross section data of <sup>58</sup>Ni(n,p)<sup>58</sup>Co, <sup>60</sup>Ni(n,p)<sup>60</sup>Co, <sup>61</sup>Ni(n,p)<sup>61</sup>Co, <sup>62</sup>Ni(n,p)<sup>62</sup>Co and <sup>64</sup>Ni(n,p)<sup>64</sup>Co reactions were calculated using the nuclear codes ALICE/ASH, EMPIRE 3.2 and TALYS 1.8. In addition, the cross sections were calculated with the empirical formulas obtained in our previous paper at 14-15 MeV. The obtained results were compared with the measured values in the literature, and with the evaluated data files (JEFF-3.3, TENDL-2017, ENDF/B-VIII.0).

        • KCI등재SCOPUS

          Theoretical study of cross sections of proton-induced reactions on cobalt

          Mustafa,Yigit 한국원자력학회 2018 Nuclear Engineering and Technology Vol.50 No.3

          Nuclear fusion may be among the strongest sustainable ways to replace fossil fuels because it does notcontribute to acid rain or global warming. In this context, activated cobalt materials in corrosion productsfor fusion energy are significant in determination of dose levels during maintenance after a coolant leakin a nuclear fusion reactor. Therefore, cross-section studies on cobalt material are very important forfusion reactor design. In this article, the excitation functions of some nuclear reaction channels inducedby proton particles on 59Co structural material were predicted using different models. The nuclear leveldensities were calculated using different choices of available level density models in ALICE/ASH code. Finally, the newly calculated cross sections for the investigated nuclear reactions are compared with theexperimental values and TENDL data based on TALYS nuclear code.

        • Poster Session:PS 0257 ; Gastroenterology : Gastric Xanthelasma an Incidental and Benign Lesion of Stomach: A Case Presentation

          ( Ece Yigit Taskin ), ( Sibel Serin ), ( Kevser Kutlu Tatar ), ( Sema Basat ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

          Background: Gastric Xanthalesmas are rare benign incidental yellow-white lesions between 0.5-10 mm in size. They are detected more frequently in female patients and the frequency of these lesions increases with age. Although the etiology of these lesions are unclear, chronic gastritis, gastrointestinal anastomosis, intestinal metaplasia, and H. pylori infection are found to be associated with GI xanthalesmas. They are usually located in antrum of the stomach in gastrointestinal tract, especially along the lesser curvature. In contrast to cutaneous xanthalesmas there is no evident association between GI xanthalesmas and hyperlipidemia. Methods: Here we present endoscopic and histological features of gastric xanthalesma in a 65 year old man with a history of chronic gastritis and iron defi ciency anemia. Results: Patient presented with iron defi ciency anemia. Upper GI endoscopy and colonoscopy has been done for investigation of the etiology. Colonoscopy showed diverticular disease of the colon. Upper GI endoscopy of the patient showed a 4mm foamy yellowish lipamatous lesion at the lesser curvature of the stomach (Image). Multiple biopsies are obtained from the lesion. The histology showed large foamy histiocytes containing a mixture of lipids in the mucosa and the submucosa. The multiple biopsies obtained from the antrum showed intestinal metaplasia and chronic gastritis with H.plylori positivity. Conclusion: Gastric xanthalesmas are asymptomatic benign and incidental endoscopic fi ndings. Even though they can be found in every part of Gastrointestinal tract from esophagus to colon, they are frequently observed in stomach. They are usually associated with chronic gastritis, Helicobacter pylori infection and intestinal metaplasia. Although the clinical signifi cance is unclear, gastric xanthalesmas are important lesions and biopsies should always be performed because they are frequently confused with malignant lesions.

        • KCI등재

          Deploying root microbiome of halophytes to improve salinity tolerance of crops

          Turgut,Yigit,Akyol,Shusei,Sato,Ismail,Turkan 한국식물생명공학회 2020 Plant biotechnology reports Vol.14 No.2

          Salinization of the soils is one of the most prominent problems threatening global food security. Root microbiome engineering using biofertilizers provides a sustainable way to increase agricultural productivity. Halophytes, which are extremely salt-tolerant plants, can tolerate up to 1300 mM NaCl. Members of the halophytic root microbiome now provide a promising solution to meet the increased demand in the agricultural output. Here, we explore the members of this microbiome and explain the plant growth-promoting functions of them. We discuss the manipulation of the root microbiome with synthetic microbial communities including keystone microorganisms of the halophytic root microbiome. Importantly, we provide a simple method in R software to fi nd these putative keystone taxa using network analysis. We believe this strategy will provide a valuable tool for future studies performing the combined investigation of the root bacteria and fungi of halophytes.

        • KCI등재SCOPUS

          Investigating the effects of ultra-rapid, rapid vs. final precise orbit and clock products on high-rate GNSS-PPP for capturing dynamic displacements

          Cemal,O.,Yigit,Ahmed,El-Mowafy,Mert,Bezcioglu,Ahmet,A.,Dindar 국제구조공학회 2020 Structural Engineering and Mechanics, An Int'l Jou Vol.73 No.4

          The use of final IGS precise orbit and clock products for high-rate GNSS-PPP proved its effectiveness in capturing dynamic displacement of engineering structures caused by earthquakes. However, the main drawback of using the final products is that they are available after approximately two weeks of data collection, which is not suitable for timely measures after an event. In this study, the use of ultra-rapid products (observed part), which are available after a few hours of data collection, and rapid products, which are available in less than 24 hrs, are investigated and their results are compared to the more precise final products. The tests are designed such that harmonic oscillations with different frequencies and amplitudes and ground motion of a simulated real earthquake are generated using a single axis shake table and the PPP was used to capture these movements by monitoring timechange of the table positions. To evaluate the accuracy of PPP using ultra-rapid, rapid and final products, their results were compared with relative GNSS positioning and LVDT (Linear Variable Differential Transformer) data, treated as reference. The results show that the high-rate GNSS-PPP solutions based on the three products can capture frequencies of harmonic oscillations and dynamic displacement with good accuracy. There were slight differences between ultra-rapid, rapid and final products, where some of the tested events indicated that the latter two produced are more accurate and provide better results compared to the ultrarapid product for monitoring short-term dynamic displacements.

        • KCI등재SCOPUS

          Lane by Lane Analysis of Vehicle Time Headways - Case Study of Izmir Ring Roads in Turkey

          Ozlem,Ceyhan,Yigiter,Serhan,Tanyel 대한토목학회 2015 KSCE JOURNAL OF CIVIL ENGINEERING Vol.19 No.5

          The studies on headway characteristics of traffic flow in Turkey are mainly dealing with signalized arterials, intersection approaches or roundabouts. Only a few studies can be found on headway characteristics of uninterrupted flow facilities and nearly none of them are on lane by lane basis. In this study, the authors are modeling headways of vehicles at zmir ring roads by lane by lane principle. The study demonstrates that lognormal distribution is an effective tool to define headways. In addition, the applicability of Cowan M3 distribution to time headways is investigated. Proportion of free vehicles is modeled for different lanes. The results show that traffic flow in the middle lane is highly affected by the vehicles in other lanes. Vehicles in the outer lane can be assumed to arrive randomly, but they are also disturbed by vehicles in other lanes. These results can be used in capacity and performance analysis of freeway segments, ramp junctions and weaving areas.

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