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      • KCI등재후보

        중학교 과학 학습 자료에서 삽화 제시 유형에 따른 학습 효과: ‘소화와 순환’ 관련 학습 자료를 중심으로

        권이영,유형빈,정은영 부산대학교 사범대학 과학교육연구소 2012 교사교육연구 Vol.51 No.2

        This study investigates the effects of the different types of illustrations that are used in the Learning Materials for the unit ‘Digestion and Circulation’ in middle school science. Two topics in the unit, the ‘Inner Structure of the Small Intestine’ for digestion and the topic of ‘Oxygen-Carrying’ for circulation were examined to develop learning materials for adopting different spatial placements of illustrations and texts, for example the ‘Separation Type’ and the ‘Unity Type’. In the ‘Separation Type’ of learning materials, the texts and illustrations were separated and for the ‘Unity Type’ of learning materials, the texts were integrated into the illustrations. Two post-tests and one questionnaire after lessons were administrated to second grade students in middle school. The study found that students preferred the ‘Unity Type’ of materials. They reacted more positively to use the ‘Unity Type’ rather than the ‘Separation Type’. The post-tests confirmed that the ‘Unity-type’ of materials was more effective in student learning as well as the retention of content, as students who used the ‘Unity Type’ of learning materials achieved higher achievement scores in the first and second post-tests. The implication of the research findings are important as it shows that science teachers have to guide students to be able to connect the texts and illustrations. It is concluded that ‘Unity Type’ illustrations should be used for certain topics in science textbooks as well as learning materials. 본 연구는 중학교 과학 학습 자료에서 삽화의 제시 유형이 학생들의 학습에 미치는 효과를 알아보고, 효과적인 삽화 제시 방안을 모색하고자 하였다. 중학교 과학 교과서의 ‘소화와 순환’ 단원에서 ‘소장의 내부 구조’ 와 ‘산소 운반’을 주제로 선정하였고, 공간적 배치에 따라 본문이 삽화와 분리되어 있는 ‘분리형’과 본문이 삽화 내부에 통합되어 있는 ‘통합형’으로 구분하여 자료를 개발하였다. 중학교 2학년 학생을 대상으로 적용한 결과, ‘통합형’이 ‘분리형’에 비해 1차와 2차 학업성취도에서 효과적인 것은 공통적이지만, 주제별 삽화와 내용의 방향성에 따라 학습 효과의 차이가 있었는데, 방향성이 있는 경우 학습 효과가 높게 나타났다. 그리고 학습자가 흥미, 이해, 학습 방법 영역에서 ‘분리형’보다 ‘통합형’에 대하여 더 긍정적으로 인식하였고, ‘통합형’을 더 선호하였다. 이러한 결과를 볼 때 과학 교과서와 학습 자료에서 주제에 따라 적합하게 ‘통합형’을 제시하고, 교사는 학생들이 본문과 삽화를 연결시킬 수 있도록 지도할 필요가 있다고 생각한다.

      • KCI등재

        RhoGDI2 induced malignant phenotypes of pancreatic cancer cells via regulating Snail expression

        Yi Bin,Hu You,Zhu Dongming,Yao Jun,Zhou Jian,Zhang Yi,He Zhilong,Zhang Lifeng,Zhang Zixiang,Yang Jian,Tang Yuchen,Huang Yujie,Li Dechun,Liu Qiuhua 한국유전학회 2022 Genes & Genomics Vol.44 No.5

        Background: Rho GDP dissociation inhibitor 2 (RhoGDI2) has been shown to contribute to the aggressive phenotypes of human cancers, such as tumor metastasis and chemoresistance. Objective: This study aimed to assess the effects of RhoGDI2 on tumor progression and chemoresistance in pancreatic cancer cells. Methods: The expression of RhoGDI2 in pancreatic cancer cells was detected by Western blot analysis. Gain-of-function and loss-of-function approaches were done to examine the malignant phenotypes of the RhoGDI2-expressing or RhoGDI2-depleting cells. The correlation between RhoGDI2 and Snail was also analyzed. Results: Differential expression of RhoGDI2 protein in pancreatic cancer cell lines was identified. Gain-of-function and loss-of-function experiments showed that RhoGDI2 induced the malignant phenotypes of pancreatic cancer cells, including proliferation, migration, invasion, and gemcitabine (GEM) chemoresistance. The upregulation of RhoGDI2 stimulated the expression of Snail, resulting in the altered expression of epithelial marker E-cadherin and mesenchymal marker Vimentin, which were characteristics of the tumorigenic activity of epithelial-mesenchymal transition. The expression of RhoGDI2 and Snail was upregulated in clinical tumor samples, and higher expression of RhoGDI2 or Snail was significantly associated with poor patient survival in pancreatic ductal adenocarcinoma (PDAC). Conclusion: The findings indicated that RhoGDI2 promoted GEM resistance and tumor progression in pancreatic cancer and that RhoGDI2 might be a potential therapeutic target in patients with PDAC.

      • KCI등재

        Study on Aging Characteristics and Chemical Composition of Hydrogenated Transformer Oil

        Yi-Hua Qian,Yi-Bin Huang,Qiang Fu,Zhen-Sheng Zhong 대한전기학회 2013 Journal of Electrical Engineering & Technology Vol.8 No.3

        Under the condition of Baader aging, the chemical composition variation and the influence of transformer oil aging on electrical properties such as dielectric loss factor and physicchemical properties such as interfacial tension were studied in the aging precess. Moreover, the correlation between hydrogenated transformer oil electrical and physic-chemical properties and its chemical composition variation were also investigated. The results show that these parameters of physic-chemical and electrical properties of hydrogenated transformer oil relate to each other and have closed correlation with chemical composition.

      • KCI등재

        Characterization of free and glycosidically bound volatile compounds, fatty acids, and amino acids in Vitis davidii Foex grape species native to China

        Yi-Bin Lan,Xiao-Feng Xiang,Wei-Xi Yang,Bao-Qing Zhu,Hong-Tie Pu,Chang-Qing Duan 한국식품과학회 2020 Food Science and Biotechnology Vol.29 No.12

        Berries of six Vitis davidii Foex (spine grape)cultivars (‘Baiputao’, ‘Gaoshan 1’, ‘Gaoshan 2’, ‘Seputao’,‘Miputao’, and ‘Tianputao’) were harvested from a commercialvineyard in Hunan Province in China. Free andbound volatile compounds and fatty acids were analyzedby GC–MS, and amino acids were analyzed by HPLC. ‘Tianputao’ and ‘Miputao’ were characterized by relativelyhigher concentrations of aromatic amino acids and lowerconcentrations of branched-chain amino acids. The majorfree volatile compounds of spine grapes were hexanal, (E)-2-hexenal, 1-hexanol, (E)-2-hexenol, (E)-b-damascenone,and benzeneacetaldehyde. The major glycosidically boundvolatile compounds identified were 1-hexanol, menthol,nerol, 1-butanol, 3-methyl-3-butenol, benzenemethanol, bphenylethanol,eugenol, and guaiacol. (E)-b-damascenone,benzeneacetaldehyde, guaiacol, and eugenol had odoractivity values (OAVs)[1 in all cultivar grapes. Partialleast squares discriminant analysis (PLS-DA) revealed‘Tianputao’ to be distinct from the other cultivars due to itsrelatively higher concentrations of major terpenoids,norisoprenoids, higher alcohols, and aromatic amino acids.

      • AHCISCOPUSKCI등재
      • KCI등재
      • KCI등재

        On the multiple values and uniqueness of meromorphic functions sharing small functions as targets

        Ting-Bin Cao,Hong-Xun Yi 대한수학회 2007 대한수학회보 Vol.44 No.4

        The purpose of this article is to deal with the multiple valuesand uniqueness of meromorphic functions with small functions in thewhole complex plane. We obtain a more general theorem which improvesand extends strongly the results of R. Nevanlinna, Li-Qiao, Yao, Yi, andThai-Tan.

      • KCI등재

        Fabrication of Photopolymer Hierarchical Micronanostructures by Coupling Electrospinning and Photolithography for SERS Substrates

        Wen-Yi Zhang,Xin-Ze Xiao,Chao Lv,Jia Zhao,Gong Wang,Xuan Gu,Ran Zhang,Bin-Bin Xu,Dan-Dan Zhang,Ai-Wu Li,Yong-Lai Zhang,Hong-Bo Sun 한국고분자학회 2013 Macromolecular Research Vol.21 No.3

        Reported here is the fabrication of photopolymer hierarchical micronanostructures through a combinative process of electrospinning and subsequent photolithography. Electrospun SU-8 (epoxy-based negative photoresist)nanofiber films have been patterned into gratings with periods of 100, 200, 300, and 400 μm, respectively. Deposition of a silver nanolayer on these interlaced nanofiber films would lead to the formation of various plasmonic nanostructures,and therefore, giving rise to abundant surface-enhanced Raman scattering (SERS) “hot spots”. In the detection of Rhodamine 6G (R6G), probing molecule, the resultant SERS substrates show both high sensitivity and good reproducibility. The SERS enhancement factor could reach as high as ~108, indicating high efficiency. The fabrication of patterned, highly efficient SERS substrates may hold a great promise for the integration of SERS substrates in various microdevices such as microfluidic chips.

      • SCIESCOPUSKCI등재

        Study on Aging Characteristics and Chemical Composition of Hydrogenated Transformer Oil

        Qian, Yi-Hua,Huang, Yi-Bin,Fu, Qiang,Zhong, Zhen-Sheng The Korean Institute of Electrical Engineers 2013 Journal of Electrical Engineering & Technology Vol.8 No.3

        Under the condition of Baader aging, the chemical composition variation and the influence of transformer oil aging on electrical properties such as dielectric loss factor and physic-chemical properties such as interfacial tension were studied in the aging precess. Moreover, the correlation between hydrogenated transformer oil electrical and physic-chemical properties and its chemical composition variation were also investigated. The results show that these parameters of physic-chemical and electrical properties of hydrogenated transformer oil relate to each other and have closed correlation with chemical composition.

      • KCI등재

        Effects of a Posture Correction Feedback System on Upper Body Posture, Muscle Activity, and Fatigue During Computer Typing

        Su-bin Kim,Chunghwi Yi,Seo-hyun Kim,Gyu-hyun Han,One-bin Lim 한국전문물리치료학회 2023 한국전문물리치료학회지 Vol.30 No.3

        Background: In modern society, the use of computers accounts for a large proportion of our daily lives. Although substantial research is being actively conducted on musculoskeletal diseases resulting from computer use, there has been a recent surge in interest in improving the working environment for prevention. Objects: This study aimed to examine the effects of posture correction feedback (PCF) on changes in neck posture and muscle activation during computer typing. Methods: The participants performed a computer typing task in two sessions, each lasting 16 minutes. The participant’s dominant side was photographed and analyzed using ImageJ software to verify neck posture. Surface electromyography (EMG) was used to confirm the par-ticipant’s cervical erector spinae (CES) and upper trapezius muscle activities. The EMG signal was analyzed using the percentage of reference voluntary contraction and amplitude prob-ability distribution function (APDF). In the second session, visual and auditory feedback for posture correction was provided if the neck was flexed by more than 15° in the initial position during computer typing. A 20-minute rest period was provided between the two sessions. Results: The neck angle (p = 0.014), CES muscle activity (p = 0.008), and APDF (p = 0.015) showed significant differences depending on the presence of the PCF. Furthermore, signifi-cant differences were observed regarding the CES muscle activity (p = 0.001) and APDF (p = 0.002) over time. Conclusion: Our study showed that the feedback system can correct poor posture and re-duces unnecessary muscle activation during computer work. The improved neck posture and reduced CES muscle activity observed in this study suggest that neck pain can be prevented. Based on these results, we suggest that the PCF system can be used to prevent neck pain.

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