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Incidence and case fatality of acute myocardial infarction in Korea, 2011-2020
Yeeun Seo(Yeeun Seo),Jenny Moon(Jenny Moon),Hyeok-Hee Lee(Hyeok-Hee Lee),Hyeon Chang Kim(Hyeon Chang Kim),Fumie Kaneko(Fumie Kaneko ),Sojung Shin(Sojung Shin),Eunji Kim(Eunji Kim),Jang-Whan Bae(Jang-W 한국역학회 2024 Epidemiology and Health Vol.46 No.-
김예은 ( Yeeun Kim ),임예은 ( Yeeun Lim ),전민혁 ( Minhyek Jeon ),추시은 ( Sieun Choo ),김성주 ( Seongju Kim ),권기은 ( Kieun Kwon ),황수성 ( Sooseong Hwang ),이진상 ( Jinsang Lee ) 아프리카미래학회 2023 아프리카와 미래 Vol.2 No.0
Developing countries are most vulnerable to the negative effects of climate crises since they lack either the appropriate monitoring system or a reliable infrastructure for healthcare. The paper surveys the effect of climate change on the prevalence of diabetes in the country of Eritrea. In our effort to find the country that was most severely impacted by it, we investigated changes in temperature and the percentage of forest area loss from 2009 to 2020 across 243 countries. Among them, we were able to determine that Eritrea experienced one of the most intense rates of temperature rise and forest area loss. Based on this observation, we hypothesized that the likelihood of certain diseases rises from such drastic changes in its climate. Moreover, we discovered a significant correlation between the number of patients suffering from diabetes-related diseases, temperature change, and forest area losses. Upon further inspection of Eritrea’s social, environmental, and scientific conditions, it was clear that climate change not only is a serious issue but also one that increases the prevalence of diabetes in an African country. In this comprehensive report, we propose a sustainable solution utilize existing resources to mitigate climate change and advocate for the well-being of the people in Eritrea.
Cooperative Interaction between Acid and Copper Resistance in Escherichia coli
( Yeeun Kim ),( Seohyeon Lee ),( Kyungah Park ),( Hyunjin Yoon ) 한국미생물생명공학회 2022 Journal of microbiology and biotechnology Vol.32 No.5
The persistence of pathogenic Escherichia coli under acidic conditions poses a serious risk to food safety, especially in acidic foods such as kimchi. To identify the bacterial factors required for acid resistance, transcriptomic analysis was conducted on an acid-resistant enterotoxigenic E. coli strain and the genes with significant changes in their expression under acidic pH were selected as putative resistance factors against acid stress. These genes included those associated with a glutamatedependent acid resistance (GDAR) system and copper resistance. E. coli strains lacking GadA, GadB, or YbaST, the components of the GDAR system, exhibited significantly attenuated growth and survival under acidic stress conditions. Accordantly, the inhibition of the GDAR system by 3- mercaptopropionic acid and aminooxyacetic acid abolished bacterial adaptation and survival under acidic conditions, indicating the indispensable role of a GDAR system in acid resistance. Intriguingly, the lack of cueR encoding a transcriptional regulator for copper resistance genes markedly impaired bacterial resistance to acid stress as well as copper. Conversely, the absence of YbaST severely compromised bacterial resistance against copper, suggesting an interplay between acid and copper resistance. These results suggest that a GDAR system can be a promising target for developing control measures to prevent E. coli resistance to acid and copper treatments.