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      • KCI등재후보

        A Joint Resource Allocation Scheme for Relay Enhanced Multi-cell Orthogonal Frequency Division Multiple Networks

        ( Yaru Fu ),( Qi Zhu ) 한국인터넷정보학회 2013 KSII Transactions on Internet and Information Syst Vol.7 No.2

        This paper formulates resource allocation for decode-and-forward (DF) relay assisted multi-cell orthogonal frequency division multiple (OFDM) networks as an optimization problem taking into account of inter-cell interference and users fairness. To maximize the transmit rate of system we propose a joint interference coordination, subcarrier and power allocation algorithm. To reduce the complexity, this semi-distributed algorithm divides the primal optimization into three sub-optimization problems, which transforms the mixed binary nonlinear programming problem (BNLP) into standard convex optimization problems. The first layer optimization problem is used to get the optimal subcarrier distribution index. The second is to solve the problem that how to allocate power optimally in a certain subcarrier distribution order. Based on the concept of equivalent channel gain (ECG) we transform the max-min function into standard closed expression. Subsequently, with the aid of dual decomposition, water-filling theorem and iterative power allocation algorithm the optimal solution of the original problem can be got with acceptable complexity. The third sub-problem considers dynamic co-channel interference caused by adjacent cells and redistributes resources to achieve the goal of maximizing system throughput. Finally, simulation results are provided to corroborate the proposed algorithm.

      • KCI등재

        Changes in volatile organic compounds and diff erential expression of aroma-related genes during fl owering of Rosa rugosa ‘Shanxian’

        Yaru Sun,Wenli Wang,Lan-yong Zhao,Chengshu Zheng,Fangfang Ma 한국원예학회 2019 Horticulture, Environment, and Biotechnology Vol.60 No.5

        Rosa rugosa ‘Shanxian’, a local variety of rose in Shandong Province, was studied for its aroma characteristics, includingchanges in aroma components and diff erential expression of aroma-related genes during fl owering. The volatiles emitted fromfl owers were collected by headspace solid-phase microextraction and analyzed by gas chromatography–mass spectrometry atthe budding stage, the early, half and full opening stages, and the withering stage. Sixty-six compounds were identifi ed, andthe full opening stage contained the highest level of every single aroma component compared with the other four stages. Themajor constituents of R. rugosa ‘Shanxian’ were alcohols, esters, ketones, aldehydes, phenols, and terpenes, with alcoholsbeing the most abundant. The aroma of R. rugosa ‘Shanxian’ was mainly characterized by rich fruit aromas, fl oral aromas, andsoft plant aromas. RrAAT , RrDXR , and RrDXS genes played a key role in monoterpene biosynthesis in R. rugosa ‘Shanxian’. The temporal and spatial expression of RrAAT , RrDXR , and RrDXS were measured at diff erent fl ower developmental stages. Among the three genes, the overall expression level of RrAAT was signifi cantly higher than that of RrDXR and RrDXS andwas associated with the accumulation of acetate esters in R. rugosa , which could be used as an important candidate gene forrose metabolism. Taken together, our results demonstrated that R. rugosa ‘Shanxian’ has better aromatic characteristics thanR. rugosa ‘Fenghua’. With a particularly prominent aroma that is strong and sweet, ‘Shanxian’ should be further investigatedas a valuable breeding material that could be used to enhance genetic diversity and develop new rose varieties.

      • KCI등재

        Upregulation of adiponectin by Ginsenoside Rb1 contributes to amelioration of hepatic steatosis induced by high fat diet

        Yaru Li,Shuchen Zhang,Ziwei Zhu,Ruonan Zhou,Pingyuan Xu,Lingyan Zhou,Yue Kan,Jiao Li,Juan Zhao,Penghua Fang,Xizhong Yu,Wenbin Shang 고려인삼학회 2022 Journal of Ginseng Research Vol.46 No.4

        Background: Ginsenoside Rb1 (GRb1) is capable of regulating lipid and glucose metabolism through itsaction on adipocytes. However, the beneficial role of GRb1-induced up-regulation of adiponectin in liversteatosis remains unelucidated. Thus, we tested whether GRb1 ameliorates liver steatosis and insulinresistance by promoting the expression of adiponectin. Methods: 3T3-L1 adipocytes and hepatocytes were used to investigate GRb1's action on adiponectinexpression and triglyceride (TG) accumulation. Wild type (WT) mice and adiponectin knockout (KO)mice fed high fat diet were treated with GRb1 for 2 weeks. Hepatic fat accumulation and function as wellas insulin sensitivity was measured. The activation of AMPK was also detected in the liver andhepatocytes. Results: GRb1 reversed the reduction of adiponectin secretion in adipocytes. The conditioned medium(CM) from adipocytes treated with GRb1 reduced TG accumulation in hepatocytes, which was partlyattenuated by the adiponectin antibody. In the KO mice, the GRb1-induced significant decrease of TGcontent, ALT and AST was blocked by the deletion of adiponectin. The elevations of GRb1-induced insulinsensitivity indicated by OGTT, ITT and HOMA-IR were also weakened in the KO mice. The CM treatmentsignificantly enhanced the phosphorylation of AMPK in hepatocytes, but not GRb1 treatment. Likewise,the phosphorylation of AMPK in liver of the WT mice was increased by GRb1, but not in the KO mice. Conclusions: The up-regulation of adiponectin by GRb1 contributes to the amelioration of liver steatosisand insulin resistance, which further elucidates a new mechanism underlying the beneficial effects ofGRb1 on obesity

      • KCI등재

        miR‑1294 alleviates epithelial–mesenchymal transition by repressing FOXK1 in gastric cancer

        Yaru Wang,Guangming Liu,Shijuan Sun,Junjie Qin 한국유전학회 2020 Genes & Genomics Vol.42 No.2

        Background MicroRNAs (miRNAs) have been reported play critical roles in regulating tumor development and progression. Objective This study aimed to investigate the potential effect of miR-1294 in gastric cancer (GC). Methods Reverse transcription quantitative polymerase chain reaction (RT-PCR) were performed to verify the expression level of miR-1294 and Forkhead box protein K1 (FOXK1). Overall survival data of miR-1294 for GC was analysed by logrank test. Targetscan was used to screen potential target gene of miR-1294. Dual luciferase assay was assessed to investigate the relationship between miR-1294 and FOXK1. The miR-1294 overexpression and knockdown were designed to study the biological function of miR-1294. The migration and invasion of GC cell lines were investigated by wound healing and transwell assays. Western blotting were performed to verify the expression level of epithelial marker, mesenchymal markers and FOXK1. Overexpression of FOXK1 was designed to study the rescue effects of FOXK1 in SGC7901 cell. Results miR-1294 was found downregulated in GC patients and cell lines. A higher miR-1294 expression showed a significant longer overall survival than those with a lower miR-1294 expression. miR-1294 directly targets FOXK1 and regulates the expression of FOXK1. In addition, miR-1294 regulates epithelial-mesenchymal transition (EMT) by inhibiting FOXK1 in GC cells and it can be rescued by overexpression of FOXK1. Conclusion miR-1294 alleviates EMT process in GC by targeting FOXK1.

      • KCI등재

        Bactericidal activity of strong acidic hypochlorous water against Escherichia coli O157:H7 and Listeria monocytogenes in biofilms attached to stainless steel

        Yaru Quan,김희연,신일식 한국식품과학회 2017 Food Science and Biotechnology Vol.26 No.3

        This study aims to investigate the bactericidal activity of strong acidic hypochlorous water (SAHW) against Escherichia coli O157:H7 and L. monocytogenes in bacterial biofilms. The bactericidal activity of SAHW against both bacteria in colony biofilm increased with the elevation of the available chlorine concentration (ACC) and extension of the treatment time. The survived cell counts of E. coli O157:H7 and L. monocytogenes in the biofilms were significantly (p\0.05) decreased compare to tap water at more than 30 mg/L of ACC in SAHW and 15 s of treatment time. E. coli O157:H7 and L. monocytogenes in the biofilms reduced to less than the detection limit by treatment of 50 mg/L of ACC in SAHW for 300 and 600 s, respectively. SAHW may be a potential disinfecting agent for removing bacterial biofilms from food processing equipment and other facilities.

      • Efficient Construction and Search of Motion Graph

        Yaru Yin,Yan Gao,Lizhuang Ma (사)한국CDE학회 2010 한국CAD/CAM학회 국제학술발표 논문집 Vol.2010 No.8

        Motion graph have been widely used as effective technique in the synthesis of human motions. A good motion graph should take into account both motion diversity and time cost in construction and search. However, time cost grow quickly as graph size increases. In this paper, we present a method to set up hierarchical structure, which can preserve the motion clip boundary and transition boundary between different behaviors and styles. This structure guides a faster and more reasonable graph establishment, and allows local optimization to be performed during the construction. After the building process, this structure also helps with motion graph search, by making traverse search into direct table look-up or local search. Moreover, a navigation map is introduced to conduct appropriate path when there is no direct connection between two motions. The experimental results indicate that the hierarchical structure together with navigation map could lower the computation time in construction and search, while providing a richer variety of motion styles simultaneously.

      • KCI등재

        Dynamic modeling of constrained planar multibody systems: A case of lower limbs rehabilitative robot

        Yaru Xu,Rong Liu 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.7

        An explicit equation of motion for constrained systems, called the Udwadia-Kalaba equation, opens up a new way of dynamic modeling of constrained multibody systems, which is accomplished in a straightforward and novel three-step process. However, constraint violation arises from violation of the lower-order constraint equations because the aforementioned equations incorporate only the acceleration level constraints. There are two methods, Baumgarte stabilization method (BSM) and modified method, are implemented to realize the constraint violation suppression. The comparison of the BSM and the modified method is provided, based on numerical simulations for a sample constrained system that represents a lower limbs rehabilitative robot with continuous passive motion for therapy and rehabilitation. The results of numerical simulation obtained by the modified method are superior to that obtained by BSM, which confirms the numerical effectiveness and accuracy of the explicit solution based on the modified method to the constrained planar multibody systems.

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