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应验 ( Ying¸ Yan ) 성균관대학교 성균중국연구소 2021 중국사회과학논총 Vol.3 No.2
“选贤任能”是党的十九届四中全会提出的国家制度和治理的显著优势之一。“选贤任能”制度包含了“任人唯贤”的干部路线和“德才兼备”的干部标准, 并具有代表性强、选拔全面、有利于稳定等比较优势。“选贤任能”这一理念自原始洪荒时期起萌芽, 后经历禅让制、世袭制、察举制、科举制、委任制、选任制、考任制等模式流变, “贤能”的标准与“选任”的程序得到了极大的丰富。从制度理论上分析, “选贤任能”制度又体现出了制度变迁与制度依赖的特点, 在一定时期促进了国家的稳定和治理的有序, 但也阻碍了国家的转型发展。在新时代, 要继续推进“选贤任能”制度的革新, 使其更好适应国家治理现代化的需求。 Selection plus election (选贤任能制度), a modernized version of Confucian meritocracy, is written as a key strategy for the stability of the China Communist Party (CPC) leadership system. For short, the selection plus election system is a personnel system with Chinese characteristics and it has strong vitality and strength as proven by practice. The selection plus election system is a scientific system formed from the primitive flood and famine period (洪荒时期), andthen experienced the changes of models such as abdication system (禅让制), hereditary system (世袭制), examination system (察举制), imperial examination system (科举制), appointment system (委任制), and selection system(选任制). Reforms and learning should be continued to promote the innovation of the selection plus election system to make it better adapt to the needs of the modernization of national governance in China. The selection plus election system is not elite politics, nor democracy merely based on popular election, but a hybrid system based more on meritocratic leadership. More understanding and tolerance should be given to this experiment and further research should be conducted to analyse this system as well.
Yan-Jin Huang,Monica Parry,Ying Zeng,Yan Luo,Jing Yang,Guo-Ping He 한국간호과학회 2017 Asian Nursing Research Vol.11 No.3
Purpose: Early detection and management of coronary heart disease (CHD) are embedded into many community health service and primary care practices in western countries. The Framingham CHD risk score has been used to predict CHD and mortality for nearly 20 years, and it has predicted CHD event risk accurately in multiethnic populations. The aim of this study was to access the effect of a 6-month community-based intervention on CHD risk in individuals at high risk. Methods: A randomized controlled trial of individuals with a high 10-year CHD risk were recruited from two communities in China. Individuals in the intervention group (n ¼ 53) received a 3-month group education and a 3-month coaching session. Physical examination and self-report questionnaires were used to collect both pre- and postintervention data on blood pressure, glucose, cholesterol, body mass index, smoking, depression, and health-related quality of life (HRQoL). Results: A total of 102 participants (85.0%) completed the 6-month study. Compared with the usual care group, the intervention group had a 5 mmHg greater reduction in systolic blood pressure (t = 2.01, p = .047), larger declines in glucose (t = 2.49, p = .015), cholesterol (t = 2.44, p = .017), body mass index (t = 2.58, p = .011), and depression (t = 2.05, p = .043), and better reports of HRQoL (t = 3.36, p = .001). No significant group differences in smoking behaviors were reported. Conclusion: A 6-month community-based intervention in a CHD high-risk population improved diseaserelated risk factors, depression, and HRQoL. Results provide preliminary evidence for primary prevention of cardiovascular disease risk in a community high-risk population.
Yan Bi Cong,Fan Yan Feng,Tian Qing Hua,Wang Tao,Huang Zhi Long,Song Hong Mei,Li Ying,Jiao Lei,Wu Chun Gen 대한영상의학회 2022 Korean Journal of Radiology Vol.23 No.9
Objective: This study aimed to assess the technical feasibility, efficacy, and safety of the safe triangular working zone (STWZ) approach applied in percutaneous vertebroplasty (PV) for spinal metastases involving the posterior part of the vertebral body. Materials and Methods: We prospectively enrolled 87 patients who underwent PV for spinal metastasis involving the posterior part of the vertebral body, with or without the STWZ approach, from January 2019 to April 2022. Forty-nine patients (27 females and 22 males; mean age ± standard deviation [SD], 57.2 ± 11.6 years; age range, 31–76 years) were included in group A (with STWZ approach), accounting for 54 vertebrae. Thirty-eight patients (18 females and 20 males; 59.1 ± 10.9 years; 29–81 years) were included in group B (without STWZ approach), accounting for 57 vertebrae. Patient demographics, procedure-related variables, and pain relief as assessed using the visual analog scale (VAS) were collected at different time points. Tumor recurrence in the vertebrae after PV was analyzed using Kaplan–Meier curves. Results: The STWZ approach was successful from T1 to L5 without severe complications. Cement filling was satisfactory in 47/54 (87.0%) and 25/57 (43.9%) vertebrae in groups A and B, respectively (p < 0.001). Cement leakage was not significantly different between groups A and B (p = 1.000). Mean VAS score ± SD before and 1 week and 1, 3, 6, 9, and 12 months after PV were 7.6 ± 1.8, 4.2 ± 2.0, 2.7 ± 1.9, 1.9 ± 1.5, 1.7 ± 1.4, 1.7 ± 1.1, and 1.6 ± 1.3, respectively, in group A and 7.2 ± 1.7, 4.0 ± 1.3, 3.4 ± 1.6, 2.4 ± 1.2, 1.8 ± 1.0, 1.4 ± 0.5, and 1.7 ± 0.9, respectively, in group B. Kaplan–Meier analysis showed a lower tumor recurrence rate in group A than in group B (p = 0.001). Conclusion: The STWZ approach may represent a new, safe, alternative/auxiliary approach to target the posterior part of the vertebral body in the PV for spinal metastases.
( Yan Zhang ),( De Ying Zhang ),( Yan Fang Zhao ),( Jin Wang ),( Juan Wen He ),( Jin Yong Luo ) 생화학분자생물학회(구 한국생화학분자생물학회) 2013 BMB Reports Vol.46 No.2
Although BMP6 is highly capable of inducing osteogenic differentiation of mesenchymal progenitor cells (MPCs), the molecular mechanism involved remains to be fully elucidated. Using dominant negative (dn) mutant form of type I and type II TGFβ receptors, we demonstrated that three dn-type I receptors (dnALK2, dnALK3, dnALK6), and three dn-type II receptors (dnBMPRII, dnActRII, dnActRIIB), effectively diminished BMP6- induced osteogenic differentiation of MPCs. These findings suggested that ALK2, ALK3, ALK6, BMPRII, ActRII and ActRIIB are essential for BMP6-induced osteogenic differentiation of MPCs. However, MPCs in this study do not express ActRIIB. Moreover, RNA interference of ALK2, ALK3, ALK6, BMPRII and ActRII inhibited BMP6-induced osteogenic differentiation in MPCs. Our results strongly suggested that BMP6-induced osteogenic differentiation of MPCs is mediated by its functional TGFβ receptors including ALK2, ALK3, ALK6, BMPRII, and ActRII. [BMB Reports 2013; 46(2): 107-112].
( Yan Yu Zhao ),( Kun Meng ),( Hui Ying Luo ),( Pei Long Yang ),( Peng Jun Shi ),( Huo Qing Huang ),( Ying Guo Bai ),( Bin Yao ) 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.8
A xylanase gene, xyn7c, was cloned from Paenibacillus sp. 12-11, an alkalophilic strain isolated from the alkaline wastewater sludge of a paper mill, and expressed in Escherichia coli. The full-length gene consists of 1,296 bp and encodes a mature protein of 400 residues (excluding the putative signal peptide) that belongs to the glycoside hydrolase family 10. The optimal pH of the purified recombinant XYN7C was found to be 8.0, and the enzyme had good pH adaptability at 6.5-8.5 and stability over a broad pH range of 5.0-11.0. XYN7C exhibited maximum activity at 55℃ and was thermostable at 50℃ and below. Using wheat arabinoxylan as the substrate, XYN7C had a high specific activity of 1,886 U/mg, and the apparent Km and Vmax values were 1.18 mg/ml and 1,961 ?mol/mg/min, respectively. XYN7C also had substrate specificity towards various xylans, and was highly resistant to neutral proteases. The main hydrolysis products of xylans were xylose and xylobiose. These properties make XYN7C a promising candidate to be used in biobleaching, baking, and cotton scouring processes.
Ying Yan,Yan Shao,Huiping Zhang 한국화학공학회 2013 Korean Journal of Chemical Engineering Vol.30 No.8
Adsorption kinetics of phenol on granular coconut shell activated carbon and granular coal based activated carbon was investigated by the model of homogeneous surface diffusion plus external film mass transfer with the stirred batch adsorber. The model was solved numerically by finite element and the parameter estimation was performed with the nonlinear least squares method. Through the confidence interval analysis and evaluation of the error sum of squares,higher precision of the parameter estimates can be obtained by combining more decay curves; the decay curves with the different initial solution concentrations and adsorbent dosages can be well represented with identical film mass transfer coefficient and surface diffusivity, and the effect of surface adsorption coverage on the surface diffusivity is negligible in the adsorption systems. The values of the film mass transfer coefficient and surface diffusivity are in the order of magnitude 10−5 and 10−12, respectively.
Numerical simulation of droplet dynamic behaviors in a convergent microchannel
Ying Yan,Dan Guo,Jing Luo,Shizhu Wen 한국바이오칩학회 2013 BioChip Journal Vol.7 No.4
Microfluidic devices are of high efficiency for the coalescence and manipulation of monodispersed droplets. Numbers of microfluidic applications involve the control of droplets through networks of convergent or divergent junctions. The convergent microchannels are widely applied in transporting DNA and controlling other chemical and biological reactions. But there are still some problems unsolved such as that how to merge droplets more efficiently and how to guarantee the stability of the droplet in a convergent microchannel. In this work, numerical method is used to investigate the dynamic properties of the water microdroplets suspended in the convergent microchannel filled with oil. The moving of microdroplets in the convergent microchannel is driven by the initial droplet velocity. The surface tension is taken into account in the Navier-Stokes equations. The microchannel size parameter “Da” is firstly proposed to describe the convergent microchannel geometric characteristics and through which a regime map is created to classify droplets states into total coalescence regime, partial coalescence regime and no coalescence regime respectively. The dynamic behaviors of the droplets suspended in the convergent microchannel are discussed in detail. This work would contribute to the design of convergent microchannels for better biochemical analysis.
Two New α-Pyrones and Other Components from the Cladodes of Opuntia dillenii
Ying Kun Qiu,Yan Yan Zhao,De Qiang Dou,Bi Xia Xu,Ke Liu 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.6
The aqueous ethanolic extract from the fresh cladodes of Opuntia dillenii HAW. was found to show anti-inflammatory activity. Two new α-pyrones, named opuntioside II (1) and opuntioside III (2), were isolated from the extract together with six known compounds. The structures of the new compounds were determined on the basis of chemical and physicochemical evidence.