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      • KCI등재

        Kinetic Models of Controllable Pore Growth of Anodic Aluminum Oxide Membrane

        Yan Huang,Hong-yan Zeng,Ce Zhao,Ye-qing Qu,Pin Zhang 대한금속·재료학회 2012 METALS AND MATERIALS International Vol.18 No.3

        An anodized Al2O3 (AAO) membrane with apertures about 72 nm in diameter was prepared by two-step anodic oxidation. The appearance and pore arrangement of the AAO membrane were characterized by energy dispersive x-ray spectroscopy and scanning electron microscopy. It was confirmed that the pores with high pore aspect ratio were parallel, well-ordered, and uniform. The kinetics of pores growth in the AAO membrane was derived, and the kinetic models showed that pores stopped developing when the pressure (σ) trended to equal the surface tension at the end of anodic oxidation. During pore expansion,the effects of the oxalic acid concentration and expansion time on the pore size were investigated, and the kinetic behaviors were explained with two kinetic models derived in this study. They showed that the pore size increased with extended time (r=G·t+G’), but decreased with increased concentration (r=−K·lnc -K’)through the derived mathematic formula. Also, the values of G, G’,K, and K’ were derived from our experimental data.

      • SCOPUS

        Research on Braking Process of High-speed Train with Aerodynamic Brake

        Yonghua Zhu,Weilie Shang,Xia Zhang,Hongjie Yan,Pin Wu 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.12

        The speed is higher, the kinetic energy is greater. In order to ensure the safety of a new generation train running in a high speed, it is necessary to research on its braking performance. In this paper, the braking force, running resistance, braking time, braking distance and the deceleration generated by the train with two kinds of braking wings were analyzed while the high-speed train was doing deceleration movement. And the results were compared and analyzed between the train with and without braking wing, and between the two kinds of braking wings. The results showed that the high speed train with braking wings made much contribution to the acceleration in the braking process, especially the train is in high speed.

      • KCI등재

        Machining Characteristics of Hybrid EDM with Ultrasonic Vibration and assisted Magnetic Force

        Yan-Cherng Lin,Fang-Pin Chuang,A-Cheng Wang,Han-Ming Chow 한국정밀공학회 2014 International Journal of Precision Engineering and Vol. No.

        In this investigation, an ultrasonic vibration and an assisted magnetic force are integrated with the electrical discharge machining(EDM) to develop a hybrid process of EDM with ultrasonic vibration and assisted magnetic force (EDMUVAMF), and then the hybridprocess is adopted to explore the effects of the main machining parameters on the material removal rate (MRR), electrode wear rate(EWR), surface roughness (SR) and morphologies of the machined surface in machining SKD 61 mold steels. Moreover, the effectson expelling the debris from the machining gap are also studied via evaluating the discharge waveforms, and analyzing themorphology of the machined surface. The bottleneck correlated with large area using EDM process would be overcome when theoptimal parameters of the hybrid process of EDMUVAMF is obtained. From the experimental results shown, the hybrid process ofEDMUVAMF can improve the machining performance. The MRR was increased significantly and the SR was reduced to amelioratethe machining efficiency and machined surface quality. The hybrid process revealed the potential for the applications in large areavia EDM technique.

      • KCI등재

        Design and Characterization of a Capillary-Driven and Parallelized Microfluidic Chip for Distributing a Liquid Plug

        Pin-Chuan Chen,Yan-Fong Cheng,Kung-Chia Young,Hung-Lin Hsieh,Chin-Lung Yang 한국정밀공학회 2016 International Journal of Precision Engineering and Vol.17 No.11

        To realize a portable, capillary-driven, and parallelized microfluidic chip, how to evenly distribute a liquid plug from the inlet to multiple daughter microchannels is a challenging task. Two approaches were adopted to generate sufficient capillary pressure to allow a liquid plug spontaneously flowing through bifurcation features, including enlarging the contact perimeter between the liquid plug and microchannel walls and applying hydrophilic coating to the microchannel walls. A 1-to-2 bifurcation microfluidic chip and a 1-to-4 bifurcation microfluidic chip were designed and fabricated on PMMA substrates for experiments. Initially red food dye was used to demonstrate the effectiveness of the chips, and experiment results revealed that the 1-to-2 microfluidic chip is capable of 100% liquid splitting efficiency with a CV of 5.7% whereas the 1-to-4 microfluidic chip is capable of 83% liquid splitting efficiency with a CV of 6.7%. After successfully conducting experiments with red food dye, human whole blood and blood plasma were introduced into the 1-to-2 microfluidic chips and splitting efficiency was investigated. The experiment results showed a 33% and 67% splitting efficiency for human whole blood and blood plasma, respectively. And the lower splitting efficiency can be attributed to the complex and Non-Newtonian fluidic property of the blood.

      • Research on Feature Extraction based on Deep Learning

        Wu Pin,Yan Hongjie,Shang Weilie,Zhu Yonghua,Gao Honghao 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.11

        With the development of deep learning, it has achieved impressive results in feature extraction field. This paper drives research in feature extraction based on deep learning. First, this paper gives a brief introduction on the world's research status on deep learning and principle of Restricted Boltzmann machine (RBM). Then this paper conducts reducing experiment based on RBM for handwritten digits. According to the analysis based on the results of the experiments, this paper tries to get a proper dimension which handwritten digits reduced to achieve better performance. Finally, this paper finds that it reach the goal when handwritten digits is reduced to half dimensional raw digits. This is an important foundation of deep learning layering and offers help to researchers in feature extraction based on deep learning.

      • SCIESCOPUSKCI등재

        Dietary Phytoncide Supplementation Improved Growth Performance and Meat Quality of Finishing Pigs

        Li, Han Lin,Zhao, Pin Yao,Lei, Yan,Hossain, Md Manik,Kang, Jungsun,Kim, In Ho Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.9

        We conducted this 10-wk experiment to evaluate the effects of dietary phytoncide, Korean pine extract as phytogenic feed additive (PFA), on growth performance, blood characteristics, and meat quality in finishing pigs. A total of 160 pigs ([Landrace${\times}$Yorkshire]${\times}$Duroc, body weight (BW) = $58.2{\pm}1.0kg$) were randomly allocated into 1 of 4 treatments according to their BW and sex, 10 replicate pens per treatment with 4 pigs per pen were used (2 barrows and 2 gilts). Dietary treatments were: CON, control diet; PT2, CON+0.02% PFA; PT4, CON+0.04% PFA; PT6, CON+0.06% PFA. Overall, average daily gain (ADG) was higher in PT4 (p<0.05) than in PT6, average daily feed intake (ADFI) was lower in PT6 than in CON (p<0.05). Besides ADFI decreased linearly (p<0.05) with the increased level of phytoncide and gain:feed ratio in PT4 treatment was higher (p<0.05) than CON treatment. During 5 to 10 weeks and overall, quadratic (p<0.05) effect was observed in ADG among the treatments. At the end of this experiment, pigs fed with PT4 diet had a greater (p<0.05) red blood cell concentration compared to the pigs fed CON diet. Water holding capacity increased linearly (p<0.05) with the increased level of phytoncide supplementation. Moreover, firmness, redness, yellowness, and drip loss at day 3 decreased linearly (p<0.05) with the increase in the level of phytoncide supplementation. In conclusion, inclusion of phytoncide could enhance growth performance without any adverse effects on meat quality in finishing pigs.

      • KCI등재

        Toluene abatement through adsorption and plasma oxidation using ZSM-5 mixed with γ-Al2O3, TiO2 or BaTiO3

        Caihong Qin,Hui Guo,Pin Liu,Wenwen Bai,Jiayu Huang,Xuemin Huang,Xiaoqing Dang,Dongjie Yan 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.63 No.-

        Toluene abatement through adsorption and then plasma oxidation using ZSM-5, ZSM-5-γ-Al2O3 (Z-Al), ZSM-5-TiO2 (Z-Ti), ZSM-5-BaTiO3 (Z-Ba), and AgMn/ZSM-5-BaTiO3 (AgMn/Z-Ba) as adsorbents/catalysts was investigated. The efficiency of toluene removal reached ∼100% for all the tested adsorbents/catalysts. ZSM-5 had the lowest mineralization rate (MR) of ∼43%, while Z-Ba had the highest MR (88%) with an SCO2 of ∼80%. After loading AgMn onto Z-Ba, both the breakthrough capacity of toluene and SCO2 was increased, while the production of byproduct O3 and MR was decreased. The mixed materials created a higher amount of active species capable of deeply oxidizing adsorbed toluene.

      • KCI등재

        Explore the dynamic alternation of gene PLAC4 mRNA expression levels in maternal plasma in second trimester for nonivasive detection of trisomy 21

        ( Lan Yang ),( Hai Yan Sun ),( Dao Zhen Chen ),( Mu Dan Lu ),( Ye Tang ),( Jian Pin Xiao ) 대한산부인과학회 2015 Obstetrics & Gynecology Science Vol.58 No.4

        Objective: Noninvasive prenatal detection of trisomy 21 (T21) has been achieved by measuring the ratio of two alleles of a single nucleotide polymorphism in circulating placenta specific 4 (PLAC4) mRNA in maternal plasma with a few assays in recent years. Our research is to explore the variations of PLAC4 mRNA expression level in maternal plasma with normal pregnancies in second trimester, which can provide pregnant women deeper insights with suitable detection period for the non-invasive prenatal detection of T21. Methods: We measured a serial plasma PLAC4 mRNA concentrations weekly from the same 25 singleton normal pregnant women. We recruited maternal plasma samples from 45 singleton pregnant women , comprising of 25 euploid pregnancies (control group; range, 17 to 21 weeks) and 20 T21 pregnancies (T21 group; range, 19 to 24 weeks). With the application of reverse transcription polymerase chain reaction, we achieved an insight of PLAC4 mRNA expression levels in maternal plasma during second trimester with euploid pregnancies. Results: Among the control group, the levels of PLAC4 mRNA expression in the gestation of 17 to 18 weeks were significantly less than those in the gestation of 18 to 21 weeks (P<0.05). The average PLAC4 mRNA concentration of the normal pregnant women was not higher than that of the T21 group (P>0.05). Conclusion: The PLAC4 mRNA showed a higher level of expression in the gestation of 18 to 21 weeks with an euploid pregnancy of pregnant women. We also found that there was no significant difference in plasma PLAC4 mRNA concentration between the normal and the T21 pregnancies in second trimester.

      • KCI등재

        Enhanced plasma mineralization of adsorbed toluene by optimization the hybrid support of Ag–Mn catalysts

        Caihong Qin,Wenwen Bai,Pin Liu,Jiayu Huang,Hui Guo,Xuemin Huang,Xiaoqing Dang,Dongjie Yan 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.80 No.-

        The removal of toluene using a cycling adsorption and plasma mineralization process was investigated ina packed reactor. The supports of catalysts were optimized in regards to mineralization rate (MR), CO2selectivity (SCO2), and the production of by-products. The hybrid support g-Al2O3-HY showed a muchbetter MR in comparison to that of HY alone. Using hybrid HY-g-Al2O3 as supports, loading Ag–Mn ononly HY or g-Al2O3 had a better MR than loading Ag–Mn on both HY and g-Al2O3. The stability studyshowed that intermediates accumulated on the surface of the catalyst lead to its deterioration.

      • KCI등재

        Haloperidol and Other Antipsychotics Exposure before Endometrial Cancer Diagnosis: A Population-based Case-control Study

        Wei-Ling Chen,Srinivasan Nithiyanantham,Yan-Chiao Mao,Chih-Hsin Muo,Chih-Pin Chuu,Shih-Ping Liu,Min-Wei Huang,Kuan-Pin Su 대한정신약물학회 2022 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.20 No.3

        Objective: Endometrial cancer is the most common malignancy of the female genital tract worldwide, and the associated relationship between endometrial cancer formation and various antipsychotics need to be confirmed. Methods: We conducted a case-control study by using data from Taiwan National Health Insurance Research Database to compare individual antipsychotic exposure between females with and without endometrial cancer. Among 14,079,089 females in the 12-year population-based national dataset, 9,502 females with endometrial cancer were identified. Their medical records of exposure to antipsychotics, including quetiapine, haloperidol, risperidone, olanzapine, amisulpride, clozapine, and aripiprazole, for up to 3 years before endometrial cancer diagnosis were reviewed. Daily dosage and cumulative exposure days were analyzed in the risky antipsychotic users. Additionally, the subsequent 5-year mortality rate of endometrial cancer among users of the risky antipsychotic were also analyzed. Results: Among endometrial cancer patients, the proportion of those who have used haloperidol before being diagnosed with endometrial cancer is significantly higher than other antipsychotic users. The significant odds ratio (OR) and a 95% confidence interval of 1.75 (1.31−2.34) were noted. Furthermore, haloperidol users were associated with a significantly higher 5-year mortality rate after getting endometrial cancer than non-users. Conclusion: There is a high correlation between the use of haloperidol and endometrial cancer formation. However, the underlying pathological biomechanisms require additional investigations.

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