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Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas
Mehmet Ruhi Onur,Mehmet Yalnız,Ahmet Kursad Poyraz,Ibrahim Hanifi Özercan,Yusuf Ozkan 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.1
A 39-year-old female patient presented to our hospital with epigastric pain lasting for two months. Laboratory results showed impaired glucose tolerance. Ultrasonography of the patient showed a hypoechoic, diffusely enlarged pancreas. CT revealed a large pancreas, with multiple calcifications. On MRI, a diffusely enlarged pancreas was seen hypointense on both T1- and T2-weighted images with heterogeneous enhancement after gadolinium administration. A biopsy of the pancreas revealed primary amyloidosis of islet cells. Decreased signal on T1-weighted images without inflammation findings on CT and MRI were clues for the diagnosis.