Migration of Rod into Retroperitoneal Region: A Case Report and Review of the Literature

Yaşar Bayri,Murat Sakir Eksi,Ramazan Doğrul,Demet Yalçinkaya Koç,Deniz Konya 대한척추신경외과학회 2014 Neurospine Vol.11 No.4

Spinal stabilization with fusion is the widely used method for traumatic or pathologic fracture of spine, spinal stenosis, and spondylolisthesis. Complications may emerge during or after the operations. Infection, hematoma and neurological deficits are early noticed findings. Screw and/or rod fractures present in long-term after surgery. Rod migration in out of the spinal column is a rare entity. A 67-year-old woman was visited our clinic for right leg pain. She had a previous spinal instrumentation surgery for spondylolisthesis in another center 6 years before. After radiological work-up, a distally migrated rod piece was observed in the retroperitoneal portion. The patient was operated for degenerative change; old instruments were replaced and extended to the L2 level with posterior spinal fusion. After the operation, her right leg pain improved. The asymptomatic migrated rod piece has regularly been followed clinically and radiologically, since then. Although it has rarely been reported, migration of the instrumentation material should be kept in mind. Spinal fixation without fusion makes the mechanical system vulnerable to motion effects of spine, especially in a degenerative and osteoporotic background. Long-term, even life-long follow-up is necessary for late term complications.

Elevated Serum Galectin-1 and Galectin-3 Levels in Children With Specific Learning Disorder: A Case Control Study

Yaşar Tanır,Zeynep Nur Gülle,Gökçe Sultan Uncu,Adile Merve Baki,Pervin Vural,Nusret Soylu,Abdurrahman Cahid Örengül 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.7

Objective Specific learning disorder (SLD) is a neurodevelopmental disorder in which underlying pathogenesis and etiological factors are not fully understood. Neuroinflammatory response (measured with serum levels of galectin-1 and galectin-3), which is associated with learning and memory, may play an important role in the etiopathogenesis of SLD. Aim of the present study is to examine whether serum galectin-1 and galectin-3 levels are related to SLD.Methods The current study consisted of 42 treatment-naive children with SLD and 42 control subjects. All of the subjects were assessed using semi-structured psychiatric examination to diagnose SLD and exclude attention-deficit hyperactivity disorder. Serum galectin-1 and galectin-3 levels were measured via venous blood samples.Results The SLD and control group did not differ significantly in terms of age, sex, and body mass index (BMI). The SLD group had significantly higher serum levels of galectin-1 (8.78±2.97 vs. 7.40±2.03, p=0.019) and galectin-3 (1.86±0.93 vs. 1.32±0.69, p=0.003) than the control group when controlled for age, sex, and BMI.Conclusion Higher serum levels of galectin-1 and galectin-3 in children with SLD may indicate the role of neuroinflammatory response in the pathogenesis of SLD. Other mechanisms involving galectin-1 and galectin-3 related to learning may play a part in the etiology of SLD.

Torsion of circular open cross-section with corrugated inner and outer surface

Yaşar Pala,Abdullah Pala 국제구조공학회 2020 Structural Engineering and Mechanics, An Int'l Jou Vol.73 No.1

In this study, the problem of torsion of bars with open cross section surrounded by corrugated boundaries is analyzed. An approximate analytical solution is given using perturbation technique. First, the stress analysis for circular open cross-section for arbitrary opening angle is formulated and the problem is analytically solved. Second, the open cross-section with corrugated cross section is analyzed using perturbation method. First order contributions to the stresses and the torques have been added. The results have been exemplified and compared by considering special examples.

Thrust force modelling and surface roughness optimization in drilling of AA-7075: FEM and GRA

Nafiz Yaşar 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.10

AA7075 aluminum alloy attracts scientific interest to participate in production of crucial components in aerospace, construction and automotive domains. Specifically, final products need to display equal quality to ensure the basic standards of safety in the aircraft industry. Despite the high machinability of the AA7075 alloy, hole quality may vary according to tool geometry and drilling parameters. In this study, the effects of different feed rate levels and cutting speeds on the surface roughness (Ra) and thrust (Fz) were investigated. Drilling experiments were conducted with drills of three different quality and geometry. The effects of drilling variables on the surface roughness and the thrust force according to “the smaller-the better” approach of the gray relation analysis (GRA) method have been investigated. Consequently, the highest and lowest gray relations degrees obtained were 0.828 and 0.338, respectively. Numerical analyzes for thrust force were performed with the ThirdWave AdvantEdge simulation software based on the finite element method. We also outlined that there exists an average difference of 4.9 % between the experimental and simulation thrust force values, and we proved the applicability of the finite element model.

간호사의 소진과 감정노동 및 자기효능감에 대한 연구

양야기 한국간호과학회 간호행정학회 2011 간호행정학회지 Vol.17 No.4

Purpose: This study was conducted to investigate the relationship of burn out, emotional labor and self-efficacy in nurses, and to identify predictors of burnout. Method: The participants were 268 nurses working in C university hospital in G city. Data were collected from May 1 to May 31, 2010, and analyzed using SPSS/WIN 12.0. Results: The mean score per item for burnout was 3.13, the mean emotional labor score was 3.15, and the mean of self-efficacy score was 3.42. Burnout showed negative correlation with self-efficacy (r=-.339, p=.000), and showed positive correlation with emotional labor (r=.511, p=.000). Variables that predicted burnout were emotional labor, self-efficacy, gender, number of assigned patient per duty (37.8%). Conclusion: The findings of this study indicate a need to develop programs for nurses to increase self-efficacy and to control the emotion, and the need for further studies to examine causal relationship among burn out, emotional labor and self-efficacy.

Estimating the Optimal Dexketoprofen Pharmaceutical Formulation with Machine Learning Methods and Statistical Approaches

Atakan Başkor,Yağmur Pirinçci Tok,Burcu Mesut,Yıldız Özsoy,Tamer Uçar 대한의료정보학회 2021 Healthcare Informatics Research Vol.27 No.4

Objectives: Orally disintegrating tablets (ODTs) can be utilized without any drinking water; this feature makes ODTs easy touse and suitable for specific groups of patients. Oral administration of drugs is the most commonly used route, and tabletsconstitute the most preferable pharmaceutical dosage form. However, the preparation of ODTs is costly and requires longtrials, which creates obstacles for dosage trials. The aim of this study was to identify the most appropriate formulation usingmachine learning (ML) models of ODT dexketoprofen formulations, with the goal of providing a cost-effective and timereducingsolution. Methods: This research utilized nonlinear regression models, including the k-nearest neighborhood (k-NN), support vector regression (SVR), classification and regression tree (CART), bootstrap aggregating (bagging), randomforest (RF), gradient boosting machine (GBM), and extreme gradient boosting (XGBoost) methods, as well as the t-test, topredict the quantity of various components in the dexketoprofen formulation within fixed criteria. Results: All the modelswere developed with Python libraries. The performance of the ML models was evaluated with R2 values and the root meansquare error. Hardness values of 0.99 and 2.88, friability values of 0.92 and 0.02, and disintegration time values of 0.97 and10.09 using the GBM algorithm gave the best results. Conclusions: In this study, we developed a computational approach toestimate the optimal pharmaceutical formulation of dexketoprofen. The results were evaluated by an expert, and it was foundthat they complied with Food and Drug Administration criteria.

A pilot study of the two OB associations Cygnus OB2 and Carina OB1 using the Gaia data

Beomdu Lim,Yaël Nazé,Eric Gosset,Gregor Rauw 한국천문학회 2019 天文學會報 Vol.44 No.1

Simultaneous Eco-friendly Bleaching and Retting Wastewater Treatment of Hemp Fiber with Ozone Application

Görkem Gedik,Yağmur Meltem Aydın Kızılkaya,Vedat Uyak,Ahmet Koluman 한국섬유공학회 2023 Fibers and polymers Vol.24 No.1

The main aim of this study was to reduce the biological load in the retting effluents by eliminating the microorganism and at the same time, to bleach hemp fibers in the retting liquor, with ozone treatment. In addition to prevention of the environmentalpollution, time, energy, water and chemical consumption decrease were targeted by the ozone bleaching of hemp fiber in the retting liquor. For this purpose, retting liquor was treated with ozone gas in different concentrations (5–25 g/h) anddurations (5–90 min) while hemp stems were still in it. The environmental impact was investigated by TOC (Total Organic Carbon), BOD (Biochemical Oxygen Demand) and COD (Chemical Oxygen Demand) measurements. Ozone applicationresulted in dramatic reductions on BOD and TOC values. Total bacteria count in the untreated retting liquor and ozonetreated samples was determined, up to 100% sanitation effect was achieved by ozone application. Whiteness degrees of the hemp fibers increased up to 72% with ozone application compared with the retted sample. The chemical compositions of the fibers were stated by chemical tests and oxidative damage related to ozone treatment was investigated. The lignin ratio was significantly reduced after ozone application. The results of the chemical tests were supported by FTIR measurements. The mechanical properties such as tenacity and elongation were analyzed with tensile tests. The crystallographic characteristics were investigated with XRD, the crystallinity index was increased with ozone treatment.

An Investigation of fan type anchorages applied to end of CFRP strips

M. Emin Kara,Mustafa YAŞA 국제구조공학회 2013 Steel and Composite Structures, An International J Vol.15 No.6

CFRP strips are widely used nowadays for repair/strengthening or capacity increase purposes. Sharp bending at the ends of the CFRP strips is frequently encountered at these applications. In this study, Reinforced Concrete (RC) beam specimens that were produced with 10 MPa compression strength concrete were strengthened by using bonded CFRP strips with end anchorages to tension region. The parameters that were investigated in this study are the width of the strip, the number of applied fan anchorages and whether additional layer of CFRP patch is used or not at the strip ends. Specimens were strengthened with 100 mm wide CFRP strips with one or two anchorages at the ends. In addition CFRP patch with two and three anchorages at the ends were tested for investigating the effect of the patches. Specimens that were strengthened with three anchorages at the ends with patches were repeated with 60 and 80 mm wide CFRP strips. The most successful result was obtained from the specimen that was strengthened with 80 mm wide CFRP strips with 3 end anchorages and patches among the others at the experimental program. The numbers of anchorages that were applied to ends of CFRP strips were more effective than the width of the CFRP strips onto strength and stiffness of the specimens. Due to limited space at the ends of the strips at most three anchorages could be applied.

A Different Perspective on Macroscopic Sampling of Cholecystectomy Specimens

Asuman Argon,Ayşe Yağcı,Funda Taşlı,Tulu Kebat,Senem Deniz,Nazif Erkan,Gül Kitapçıoğlu,Enver Vardar 대한병리학회 2013 Journal of Pathology and Translational Medicine Vol.47 No.6

Background: Because there may be interdepartmental differences in macroscopic sampling of cholecystectomy specimens, we aimed to investigate differences between the longitudinal sampling technique and our classical sampling technique in cholecystectomy specimens in which there was no obvious malignancy. Methods: Six hundred eight cholecystectomy specimens that were collected between 2011 and 2012 were included in this study. The first group included 273 specimens for which one sample was taken from each of the fundus, body, and neck regions (our classical technique). The second group included 335 specimens for which samples taken from the neck region and lengthwise from the fundus toward the neck were placed together in one cassette (longitudinal sampling). The Pearson chi-square, Fisher exact, and ANOVA tests were used and differences were considered significant at p<.05. Results: In the statistical analysis, although gallbladders in the first group were bigger, the average length of the samples taken in the second group was greater. Inflammatory cells, pyloric metaplasia, intestinal metaplasia, low grade dysplasia, and invasive carcinoma were seen more often in the second group. Conclusions: In our study, the use of a longitudinal sampling technique enabled us to examine a longer mucosa and to detect more mucosal lesions than did our classical technique. Thus, longitudinal sampling can be an effective technique in detecting preinvasive lesions.