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여대생의 인유두종 바이러스 및 인유두종 바이러스 백신 관련 지식과 예방접종 실태와의 상관관계
Xu, Meiling,김현지,이희수,이윤지,한동연,박소영,엄효윤,최정민,홍서진,홍예림,이경은,이혜림 이화여자대학교 간호과학대학 2017 이화간호학회지 Vol.- No.51
Purpose: Human Papillomavirus (HPV) vaccination is readily available, but immunization rate is minimal. Lack of knowledge concerning the HPV infection and vaccine is expected as the primary reason. The correlation between knowledge levels and vaccination will provide applicable guidelines for successful interventions. Method: 309 female university students have completed surveys September 2016, reporting of HPV infection knowledge, HPV vaccine knowledge, source of knowledge, and attitudes concerning vaccination. Result: HPV infection and vaccine knowledge levels were both suboptimal(9.57±1.84, 7.59±1.58), and the Internet(16.2%) was recognized as the most generally used means of obtaining information on the HPV vaccine. However, vaccination rates were reported to be low(28.2%), with lack of information(46.6%) hindering immunization. Correlations were found between HPV infection knowledge and cervical cancer insight, but the correlations between knowledge levels and vaccination rates were insignificant. Conclusion: Prior information on cervical cancer had an effect on the knowledge levels of HPV infection, but other factors were insignificant. Lack of information on the HPV vaccine was speculated, thus programs should focus on accessibility and effectiveness.
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Kim, S.,Lee, E.,Lee, S.Y.,Lee, S.S.,Lindoy, L.F. Elsevier Sequoia [etc.] 2014 Inorganica chimica acta Vol.417 No.-
The 14-membered O<SUB>2</SUB>S<SUB>2</SUB>-macrocycle L reacts with AgPF<SUB>6</SUB> in acetonitrile/dichloromethane (1:1) to yield the cyclic, double S-Ag-S bridged complex, [Ag<SUB>2</SUB>L<SUB>2</SUB>(CH<SUB>3</SUB>CN)<SUB>4</SUB>](PF<SUB>6</SUB>)<SUB>2</SUB> (2), in which each Ag(I) is bound to two exo-oriented S donors arising from different macrocycles to form a 12-membered, di-Ag metallacycle. Two PF<SUB>6</SUB><SUP>-</SUP> ions form weak intramolecular contacts [Ag...F, 2.925(2)A] between the Ag centres in a bridging bidentate fashion. The coordination sphere of each Ag is completed by two weakly bound acetonitrile molecules. The respective macrocyclic ligands are arranged trans to the mean plane through the metallacycle. When the above synthetic procedure was repeated employing methanol/dichloromethane (1:1) as solvent, a complex of type [Ag<SUB>2</SUB>L<SUB>2</SUB>](PF<SUB>6</SUB>)<SUB>2</SUB> (3) was obtained whose structure incorporates a similar 12-membered metallacycle but with the respective macrocyclic rings now oriented towards the same side of the metallacyclic plane. The reaction of L with AgCF<SUB>3</SUB>SO<SUB>3</SUB> yields [Ag<SUB>2</SUB>L<SUB>2</SUB>(CF<SUB>3</SUB>SO<SUB>3</SUB>)<SUB>2</SUB>].2CH<SUB>3</SUB>CN (4) whose structure resembles that of [Ag<SUB>2</SUB>L<SUB>2</SUB>(CH<SUB>3</SUB>CN)<SUB>4</SUB>](PF<SUB>6</SUB>)<SUB>2</SUB> (2); each complex unit incorporates a di-Ag(I) 12-membered metallacycle, with symmetrical bridging bidentate CF<SUB>3</SUB>SO<SUB>3</SUB><SUP>-</SUP> ions weakly linking Ag centres. Long Ag1...Ag1C contacts are present between pairs of complex units. Reaction of Cu(CH<SUB>3</SUB>CN)<SUB>4</SUB>PF<SUB>6</SUB> (one equiv.) with L in methanol/dichloromethane (1:1) resulted in isolation of [CuL<SUB>2</SUB>]PF<SUB>6</SUB> (5) incorporating a distorted tetrahedral S<SUB>4</SUB>-coordination sphere, with each macrocycle binding as a bidentate ligand via its two (exo-orientated) S atoms. In contrast, reaction of [Cu(CH<SUB>3</SUB>CN)<SUB>4</SUB>]PF<SUB>6</SUB> (two equiv.) with L in either acetonitrile/dichloromethane (1:1) or methanol/dichloromethane (1:1) yielded [Cu<SUB>2</SUB>L<SUB>3</SUB>]PF<SUB>6</SUB> (6) in which the Cu(I) centres are bound exo to the macrocyclic cavity by individual S-donors from one L, with the coordination sphere of each Cu(I) completed by out-of-plane binding of the S<SUB>2</SUB>O donors from a second L. Unsymmetrical F...Cu contacts from a PF<SUB>6</SUB><SUP>-</SUP> anion weakly link the pair of Cu centres in a bridging bidentate fashion.
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Jin, Q.,Li, L.,Moon, J.S.,Cho, S.K.,Kim, Y.J.,Lee, S.J.,Han, N.S. Society for Bioscience and Bioengineering, Japan ; 2016 Journal of bioscience and bioengineering Vol.121 No.5
<P>The n-form of lactate, which causes metabolic stress upon excessive dietary intake, is mainly produced by Leuconostoc sp., the predominant species in sauerkraut. To shift the metabolic flux of D-lactate from pyruvate to L-lactate, we expressed the L-lactate dehydrogenase (ldhL) gene in Leuconostoc mesenteroides ATCC 8293. The IdhL gene from Lactobacillus plantarum was introduced into L. mesenteroides using the shuttle vectors pLeuCM and pLeuCM42. To elevate the expression level of IdhL in L. mesenteroides, the nucleotides for pyruvate kinase promoter were fused to IdhL and cloned into above vectors to construct pLC18pkL and pLC42pkL. As results, introduction of pLC42pkL in L. mesenteroides significantly improved both L-LDH activity and L-lactate productivity during fermentation, decreasing the D-/L-lactate ratio. When used as a starter culture for sauerkraut fermentation, recombinant L. mesenteroides harboring pLC42pkL increased L-lactate concentration and decreased D-lactate concentration compared to the wild type strain. We newly developed a recombinant L. mesenteroides which has high L-lactate dehydrogenase activity and applied this strain to minimize the harmful effect of D-lactate during the sauerkraut fermentation. To the best of our knowledge, we demonstrate for the first time the effective use of recombinant Leuconostoc sp. for quality improvement of fermented foods. (C) 2015, The Society for Biotechnology, Japan. All rights reserved.</P>
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Interaction of copper(II) with N-substituted bis(2-pyridylmethyl)amine derivatives
Kim, M.,Mora, C.,Lee, Y.H.,Clegg, J.K.,Lindoy, L.F.,Min, K.S.,Thuery, P.,Kim, Y. Elsevier 2010 Inorganic chemistry communications Vol.13 No.10
<P>Interaction of copper(II) with the N-substituted bis(2-pyridylmethyl)amine derivatives, (R)-N-1,N-1-bis (pyridine-2-ylmethyl)butane-1,2-diamine (L-1) and (R)-2-(bis(pyridin-2-ylmethyl)amino)butan-1-ol (L-2), has led to isolation of optically active [Cu(L-1)Cl]PF6 (1) and [Cu(L-2)Cl]ClO4 (2), respectively. The X-ray structures of (1) and (2) show that the copper is bound to all four heteroatoms of the respective ligands as well as to a chlorine atom in a distorted square pyramidal arrangement in which the three nitrogens of L-1 or L-2 occupy three positions of each basal plane while the fourth position is occupied by the chloro ligand; apical sites in each case are filled by the amine donor from the NH2-substituted butane arm in L-1 or the (protonated) alcohol oxygen of the 2-aminobutane-1-ol substituent in L-2. To a first approximation the coordination geometry in 2 is distorted square pyramidal; however, the remaining (axial) site on each copper centre is involved in a long contact (2.96 angstrom) with a bound chloro ligand from an adjacent complex which connects individual complex units in a zigzag 1-D polymeric chain, so that the coordination geometry could also be seen as pseudo-octahedral. A temperature-dependent magnetic study revealed the presence of ferromagnetic exchange coupling between copper centres in the chain reflecting the orthogonal structure between the chloro-bridged copper(II) ions; in contrast, and as expected, the discrete complex 1 is magnetically dilute. (C) 2010 Elsevier B.V. All rights reserved.</P>
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Mapping the Posterior Ledge and Optic Foramen in Orbital Floor Blowout Fractures
Wong Yu Cong,Goh Doreen S.L.,Yoong Celine S.Y.,Ho Cowan,Cai Elijah Z.,Hing Angela,Lee Hanjing,Nallathamby Vigneswaran,Yap Yan L.,Lim Jane,Gangadhara Sundar,Lim Thiam C. 대한성형외과학회 2023 Archives of Plastic Surgery Vol.50 No.4
Background The posterior ledge (PL) is a vital structure that supports the implant posteriorly during orbital floor reconstruction. This study describes a technique for mapping the PL in relation to the infraorbital margin (IM) in patients with orbital floor blowout fractures. This study establishes the location of the optic foramen in relation to the PL. Methods Facial computed tomography (FCT) scans of 67 consecutive patients with isolated orbital floor blowout fractures were analyzed using Osirix. Planes of reference for orbital fractures, a standardized technique for performing measurements on FCT, was used. Viewed coronally, the orbit was divided into seven equal sagittal slices (L1 laterally to L7 medially) with reference to themidorbital plane. The distances of PL from IM and location of optic foramen were determined. Results The greatest distance to PL is found at L5 (median: 30.1mm, range: 13.5– 37.1mm). The median and ranges for each slice are as follows: L1 (median: 0.0mm, range: 0.0–19.9mm), L2 (median: 0.0mm, range: 0.0–21.5mm), L3 (median: 15.8mm, range: 0.0–31.7mm), L4 (median: 26.1mm, range: 0.0–34.0mm), L5 (median: 30.1mm, range: 13.5–37.1mm), L6 (median: 29.0mm, range: 0.0– 36.3mm), L7 (median: 20.8mm, range: 0.0–39.2mm). The median distance of the optic foramen from IM is 43.7mm (range: 37.0– 49.1) at L7.
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백남원(N.W. Paik),박두용(D.Y. Park),장익선(I.S. Chang),신용철(Y.C. Shin),이정인(J. l. Lee) 한국환경보건학회 1988 한국환경보건학회지 Vol.14 No.2
Airborne dust and asbestos fiber concentrations were determined in subway stations located in Seoul area. Two stations, such as Eulchiro 4.Ka Station of Une #2, constructed during a period of 1980-1984 and Hyehwa Station of Une #4, opened in 1985, were selected. The results of the study are as follows. 1. Daily tirne.weighted average (1W A) concentrations of airborne dusts from 07:00 to 20:00 hours in Line #2 and μne #4 were 0.43:t0.08 mg/m3 and 0.37:t0.12 mg/m3 , respectively. Thus, the dust levels in Líne #2 were significant1y higher than the levels in Line #4( p < 0.05). 2. Dust levels in the morning (07:00-11:00 hours), noon (1 1:00-16:00 hours) and in the evening (1 6:00-20:00 hours) in Líne #2 were 0.47:t0.17 mgjm3 , 0.37:t0.08 mg/m3 , and 0.46土0.07 mg/m3 respectively. Thus, dust levels in the morning and evening (i.e., during rush hours) were significantly higher than levels in the noon ( p < 0.02). However, there was no such difference in dust levels by time in Líne #4. 3. Airborne total dust concentrations were well below the occupational health standard of 10 mg/m3 , however, the levels were exceeding the ambient air standard recommended by the Korean Environment Administration. 4. All of airborne asbestos fiber concentrations were equal to or below 0.005 fibers/cc. The levels are within both occupational health standards and U .S. EPA criterìa. 5. A consideration should be given to the improvements of c1eaning methods (such as use of vacuum c1eaning instead of brushing) and the existing ventilation (such as more aìr change and filtration of supply air) for a reduction of dust levels. 6. It is recommended that routine monitoring of aìrborne dusts and asbestos fibers be conducted because more dusts and asbestos fibers can be produced in the aìr due to the deterioration of facilities by age and water damage in future.
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Lee, B.L.,Kang, J.H.,Kim, H.M.,Jeong, S.H.,Jang, D.S.,Jang, Y.P.,Choung, S.Y. Pergamon Press 2016 Nutrition research Vol.36 No.12
<P>Polyphenols exert beneficial effects on vision. We hypothesized that polyphenol components of Vaccinium uliginosum L. (V.U.) extract protect retinal pigment epithelial (RPE) cells against blue light-induced damage. Our aim was to test extracts containing polyphenol components to ascertain effects to reduce damage against blue light in RPEs. We measured the activity in fractions eluted from water, ethanol, and HP20 resin (FH), and found that the FH fraction had the highest beneficial activity. We isolated the individual active compounds from the FH fraction using chromatographic techniques, and found that FH contained flavonoids, anthocyanins, phenyl propanoids, and iridoids. Cell cultures of A2E-laden ARPE-19 exposed to blue light after treatment with V.U. extract fractions and their individual constituents indicated improvement. V uliginosum L extract fractions and constituent compounds significantly reduced A2E photo-oxidation-induced RPE cell death and inhibited intracellular A2E accumulation. Furthermore, Balb/c male mice were exposed to blue light at 10000 lux for 1 h/d for 2 weeks to induce retinal damage. One week after the final blue light exposure, retinal damage evaluated revealed that the outer nuclear layer thickness and nuclei count were improved. Histologic examination of murine photoreceptor cells demonstrated that FH, rich in polyphenols, inhibited the loss of outer nuclear layer thickness and nuclei. Our findings suggest that V.U. extract and eluted fractions are a potential source of bioactive compounds that potentially serve a therapeutic approach for age-related macular degeneration. (C) 2016 Elsevier Inc. All rights reserved.</P>
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AISI 5160 스프링강에서 비금속 개재물과 수소의 상호작용에 의한 연구
이기영,이재영,이성만,이종람 대한금속재료학회(대한금속학회) 1984 대한금속·재료학회지 Vol.22 No.11
The hydrogen Thermal Analysis experiments have been carried out for the identification of hydrogen trapping character by nonmetallic inclusions in AISI 5160 spring steel. It was found that oxide inclusions including Fe-oxide, Al₂O₃and SiO₂have a strong interaction with hydrogen relative to the other defects such as the cementite-ferrite interfaces and microvoids. Also, the trap activation energies of hydrogen for each inclusion were determined as follows. They are 50.6 kJ/mole and 69.5 kJ/mole for the Fe-oxides like Fe₃O₄, and Fe₂O₃, 86.2 kJ/mole for the Al₂O₃and 112.1 kJ/mole for the SiO₂respectively. The thermal analysis technique could be used to predict the fatigue properties of the steel by identifying the nonmetallic inclusions and determining the amount of them in the steel.
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