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- 저자 : Xu Minglong (검색결과 2 건)
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Nonlinear Aeroelastic Analysis of Heated Curved Panels in Supersonic Air Flow
Zhou Jian,Xu Minglong,Yang Zhichun 한국항공우주학회 2020 International Journal of Aeronautical and Space Sc Vol.21 No.4
A nonlinear aeroelastic model for a two-dimensional heated curved panel in supersonic air flow is established by using Galerkin method. The von Karman large deflection theory and the third-order piston theory appended with the static aerodynamic loading are used in the governing equations. The static aero-thermal deflection of the curved panel is firstly obtained by using Newton iterative approach. Then the stability boundary under different temperature elevations is achieved by using Lyapunov’s indirect method. Lastly, the motion equations of a heated curved panel in supersonic air flow are solved by a fourth-order Runge–Kutta numerical scheme. Time history responses, phase plots, Poincare maps and bifurcation diagrams are used for better understanding of the pre/post-flutter responses of a curved panel by varying parameters, including curvatures, dynamic pressures and temperature elevations. The results demonstrate that the flutter boundary drops significantly with increasing temperature elevation for panels with small curvatures. However, the flutter boundary almost keeps the same for panels with large curvatures. The nonlinear flutter characteristics of the curved panel differs from those of flat panels significantly, the nonlinear flutter response of heated curved panels changes from static equilibrium point or LCO to chaos with the increase of temperature elevation or dynamic pressure and the static, LCO motions also exist in the chaotic area. For panels with large curvatures, the chaotic motions cannot occur, and the amplitude of LCO is limited in a certain range.
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The role of microenvironment in aggregation of the 293-human embryonic Kidney cells
Wensong Tan,Liang Zhao,Li Fan,Xu Zhang,Minglong Zhu 한국화학공학회 2007 Korean Journal of Chemical Engineering Vol.24 No.5
cells. Key factors such as calcium, magnesium and shear stres were investigated in detail and cell aggregate size con-trol was applied to facilitate cell retention improvement. It was found that the concentration of calcium ion affectedthe aggregation of 293-HEK cells drastically and exhibited direct proportion to the average diameter of 293-HEK cellaggregates. Similar effect was also discovered in magnesium but to a lower extend. Results also showed the growthof 293-HEK cells was influenced when the concentrations of calcium or magnesium ions were below 0.1 mol/L,and that was more significant with magnesium. Furthermore, aggregation as well as growth was affected by hard in-trolled to proper size as anticipated and the average sedimentation speed of agregated cells increased about 20 timesto single cells. This is highly advantageous to cell retention improvement either in perfusion cultures or media exchangebefore adenovirus infection by proper control of the cell aggregate size, and thus a high cell concentration and ad-enovirus production potentially can be achieved.
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