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Xinliang Zheng,Juan Feng,Jiarui Zhang,Hongna Xing,Jiming Zheng,Mingzi Wang,Yan Zong,Jintao Bai,Xinghua Li 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2016 NANO Vol.11 No.3
High-quality neodymium oxychlorides nanocrystals with cubic shape were synthesized by a nonhydrolytic thermolysis route. The morphology and crystal structure of the neodymium oxychlorides nanocubes were characterized by transmission electron microscopy at the nanoscale. Transmission electron microscope (TEM) image shows that the neodymium oxychlorides nanocrystals are nearly monodispersed with cube-like shape. X-ray diffraction (XRD) and selected area electron diffraction (SAED) patterns of numerous neodymium oxychlorides nanocubes suggest a pure crystal phase with tetragonal PbFCl matlockite structure. HRTEM image of individual neodymium oxychlorides nanocubes indicate that each nanocubes have a singlecrystalline nature with high quality. Unlike the anti-ferromagnetism of the bulk, the neodymium oxychlorides nanocubes show clearly anomalous ferromagnetic characteristic at room temperature. This finding provides a new platform for the exploration of diluted magnetic semiconductors, rare earth-based nanomaterials and so on.
Artificial neural network‑based FCS‑MPC for three‑level inverters
Xinliang Yang,Kun Wang,Jongseok Kim,Ki-Bum Park 전력전자학회 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.12
Finite control set model predictive control (FCS-MPC) stands out for fast dynamics and easy inclusion of multiple nonlinear control objectives. However, for long horizontal prediction or complex topologies with multiple levels and phases, the required computation burden surges exponentially as the increases of candidate switch states during one control period. This phenomenon leads to longer sample period to guarantee enough time for traverse progress of cost function minimization. In other words, the allowed highest switching frequency is bounded considerably far from the physical limits, especially for wide-band semiconductor applications. To overcome this issue, the parallel computing characteristic of artificial neural network (ANN) motivates the idea of an ANN-based FCS-MPC imitator (ANN-MPC). In this article, ANN-MPC is implemented on a neutral point clamped (NPC) converter using a shallow neural network. The expert (FCS-MPC) is initially designed, and the basic structure, including activation function selection, training data generation, and offline training progress, and online operation of the imitator (ANN-MPC) are then discussed. After the design of the expert and imitator, a comparative analysis is conducted by field programmable gate array (FPGA) in-the-loop implementation in MATLAB/Simulink environment. The verification results of ANN-MPC show highly similarly qualified control performance and considerably reduced computation resource requirement.
Melt Superheating on the Microstructure and Mechanical Properties of Diecast Al-Mg-Si-Mn Alloy
Wenchao Yang,Xinliang Yang,Shouxun Ji 대한금속·재료학회 2015 METALS AND MATERIALS International Vol.21 No.2
The application of aluminium alloys in automotive body structure is one of the main developments in recentyears. The increase of the mechanical properties of the ductile die-casting is one of the most critical topics forthe application. In this work, the effect of melt superheating on the morphology, size and distribution of α-Alphase and Fe-rich intermetallics, and on the mechanical properties of the Al-Mg-Si-Mn diecast alloy wasinvestigated. The results showed that the refined microstructure could be obtained through melt superheating. The volume fraction of dendritic α-Al phase and the Fe-rich intermetallic phase formed in the shotsleeve was significantly reduced, resulting in the refined microstructure. Overall, the melt superheatingcould improve the mechanical properties of the yield strength, ultimate tensile strength, and elongation ofthe diecast Al-Mg-Si-Mn alloy. And, the Fe-rich intermetallic phase formed in the shot sleeve with thecoarse compact morphology and formed in the die cavity with the fine compact particles were identifiedas the same α-Al12(Fe,Mn)3Si composition in the present experimental conditions, which was not affectedby the melt superheating.
Shujun Sun,Xinliang Pan,Limin Zhao,Jianming Zhou,Hongzeng Wang,Yonghong Sun 대한이비인후과학회 2016 Clinical and Experimental Otorhinolaryngology Vol.9 No.3
Objectives. We sought to identify the expression of CD68-tumor-associated macrophages (TAMs) and CD34-microvascular density (MVD) in laryngeal squamous cell carcinoma (LSCC), to study the relationship with clinical pathological parameters and to determine whether their expression is predictive of disease. Methods. Pathologically confirmed 45 LSCC tissue and 20 peritumoral non-tumor tissue were examined. Immunohistochemical studies were used to detect the expression of CD68-TAMs and CD34-MVD. Results. The positive expression rate of CD68 in LSCC tissue was 82% (37/45), which was higher than the 10% (2/20) expression rate of the peritumoral tissue (P<0.05). The CD34-MVD positive expression rate in the LSCC tissue was 26.5±6.4, which obviously higher than 12.2±4.0 expression rate of the peritumoral tissue (P<0.05). The positive expression rates of both CD68 and CD34-MVD were higher in the lymph node metastasis (LNM) positive group than in the LNM negative group. The expression of CD68 had positive correlation with CD34-MVD. The 5-year disease-free survival rate in the group with the low CD68 expression was significantly higher than that in the group with high CD68 expression (76% vs. 42%, respectively). Conclusion. The high expression of CD68-TAMs in LSCC and its positive correlation with CD34-MVD illustrates that both play an important role in promoting the metastasis and angiogenesis of this cancer. Their expression was also positively correlated with the prognoses of these patients, suggesting that they could be used as important prognostic markers for LSCC.
( Lili Tian ),( Xinliang Wu ),( Hangqian Yu ),( Fengying Yang ),( Jian Sun ),( Tiezhong Zhou ),( Hong Jiang ) 한국미생물생명공학회 2022 Journal of microbiology and biotechnology Vol.32 No.10
The rise of methicillin-resistant Staphylococcus aureus (MRSA) has resulted in significant morbidity and mortality, and clinical treatment of MRSA infections has become extremely difficult. Sortase A (SrtA), a virulence determinant that anchors numerous virulence-related proteins to the cell wall, is a prime druggable target against S. aureus infection due to its crucial role in the pathogenicity of S. aureus. Here, we demonstrate that isovitexin, an active ingredient derived from a variety of traditional Chinese medicines, can reversibly inhibit SrtA activity in vitro with a low dose (IC<sub>50</sub>=24.72 μg/ml). Fluorescence quenching and molecular simulations proved the interaction between isovitexin and SrtA. Subsequent point mutation experiments further confirmed that the critical amino acid positions for SrtA binding to isovitexin were Ala-92, Ile-182, and Trp-197. In addition, isovitexin treatment dramatically reduced S. aureus invasion of A549 cells. This study shows that treatment with isovitexin could alleviate pathological injury and prolong the life span of mice in an S. aureus pneumonia model. According to our research, isovitexin represents a promising lead molecule for the creation of anti-S. aureus medicines or adjuncts.
Shear lag effect of varied sectional cantilever box girder with multiple cells
Zengwei Guo,Xinliang Liu,Longjing Li 국제구조공학회 2022 Structural Engineering and Mechanics, An Int'l Jou Vol.84 No.3
This paper proposes a modified bar simulation method for analyzing the shear lag effect of variable sectional box girder with multiple cells. This theoretical method formulates the equivalent area of stiffening bars and the allocation proportion of shear flows in webs, and re-derives the governing differential equations of bar simulation method. The feasibility of the proposed method is verified by the model test and finite element (FE) analysis of a simply supported multi-cell box girder with constant depth. Subsequently, parametric analysis is conducted to explore the mechanism of shear lag effect of varied sectional cantilever box girder with multiple cells. Results show that the shear lag behavior of variable box-section cantilever box girder is weaker than that of box girder with constant section. It is recommended to make the gradient of shear flow in the web with respect to span length vary as smoothly as possible for eliminating the shear lag effect of box girder. An effective countermeasure for diminishing shear lag effect is to increase the number of box chambers or change the variation manner of bridge depth. The shear lag effect of varied sectional cantilever box girder will get more server when the length of central flanges is shorter than 0.26 or longer than 0.36 times of total width of top flange, as well as the cantilever length exceeds 0.29 times of total length of box’s flange. Therefore, the distance between central webs can adjust the shear lag effect of box girder. Especially, the width ratio of cantilever plate with respect to total length of top flange is proposed to be no more 1/3.
Ping Wang,Shang Gao,Xinliang Chen,Li Yang,Tian Cao,Bingyu Fan,Jin Liu,Xianhai Hu 한국고분자학회 2022 Macromolecular Research Vol.30 No.7
The polycaprolactone (PCL)-b-polyethylene glycol (PEG) oligomer (Oli) and its derivative containing ionic elements (ILs) were used as interfacial compatibilizers and regulators, and the polylactic acid (PLA)/PCL/Oli and PLA/PCL/ILs blends were prepared by solution blending. The effects of Oli and ILs on the phase interfacial properties, aggregated structure, crystallization and mechanical properties of PLA/PCL blends were systematically studied. The results show that the ILs with strong interfacial emulsification ability can improve the dispersion of PCL in PLA matrix, and enhance the two-phase interfacial adhesion. When the content of ILs is 5 %, ion clusters can form and alleviate the restricted crystallization of PCL, and promote the segment movement of PLA through the non-covalent bonding of ionic elements. So the crystallization ability of PLA and PCL improve simultaneously. ILs have a strong regulatory effect on the phase interfacial morphology and aggregated structure of PLA/PCL blends, and the PLA/PCL blends containing high content of 5 % ILs can significantly improve the mechanical properties of PLA/PCL blends.