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        Walnut Meal Extracts Rich In Polyphenols Mitigate Insulin Resistance and Modulate Gut Microbiota in High Fat Diet-Fed Rats

        Xingping He,Dan Chen,Yan Guo,Xi Zhang,Yage Ma,Shenglan Zhao 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.6

        Walnut kernel is a traditional Chinese herb recorded in the Chinese Pharmacopoeia with the efficacies of invigorating kidney, tonifying lung, and relaxing bowel. However, the potential mechanisms were unclear. This article aims to uncover the interdict mechanisms of walnut meal extracts (WMP) on high-fat diet (HFD) induced metabolic disorders in rats and reveal how the WMP benefits are associated with changes in the intestinal flora. Sprague-Dawley (SD) rats were fed a standard chow diet or an HFD for 18 weeks. After 6 weeks, the HFD rats were supplemented with 750 mg WMP/kg body weight or the vehicle for 12 weeks. The structure of gut microbiota was assessed by analyzing 16S rDNA sequences. WMP suppressed the weight gain and visceral obesity. WMP treatment also improved lipid profiles and increased antioxidative activities. WMP fully reversed hepatic steatosis with the upregulation of adipocytokines involved in lipid catabolism (e.g., adiponectin, PPAR-γ, visfatin, CEBPα) and the increased activities of lipoprotein lipase and hormone-sensitive lipase, which were associated with glucose tolerance improvement and insulin resistance (IR) mitigation. As revealed by 16S rDNA sequencing, WMP restored the diversity of intestinal flora reduced by HFD. WMP dramatically reduced the abundance of Gram-negative bacteria, especially Fusobacterium varium and Bacteroides vulgatus, and sharply increased the abundance of Lactobacillus animalis decreased by HFD. Our findings demonstrated that WMP suppressed the weight gain and adiposity in HFD-fed rats and fully reversed HFD induced IR and hepatic steatosis while dramatically reducing the abundance of Fusobacteriaceae and Enterobacteriaceae, underscoring the gut-liver axis as a primary target of walnut polyphenols.

      • KCI등재

        THE GENERALIZED WEIGHTED MOORE-PENROSE INVERSE

        Sheng, Xingping,Chen, Guoliang 한국전산응용수학회 2007 Journal of applied mathematics & informatics Vol.25 No.1

        In this paper, we definite a generalized weighted Moore-Penrose inverse $A^{+}_{M,N}$ of a given matrix A, and give the necessary and sufficient conditions for its existence. We also prove its uniqueness and give a representation of it. In the end we point out this generalized inverse is also a prescribed rang T and null space S of {2}-(or outer) inverse of A.

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        Numerical Simulation of Heat Transfer Characteristics of Capillary Radiant Heating Floor

        Shenghua Fu,Yang Pan,Xingping Wan,Jiyue Wang,Xiaofeng Jia,Xinmei Luo,Hongqiang Ma 대한토목학회 2024 KSCE Journal of Civil Engineering Vol.28 No.2

        In order to study the temperature transference characteristics of capillary radiant heating ground, a glowing temperature change flooring model is typically established to analyze the influence of different factors on the heat transfer characteristics of the heating system. The results show that the distribution of covering temperature is uneven in the radiant heating system, and the fluctuation amplitude increases with the increase of the pipe spacing. At the same time, the change of the surface temperature is further analyzed for the finishing layer material on the radiant heating storey. The results show that the change of the capillary tube spacing leads to a smaller change in the floor exterior temperature when the wood floor is used as the finishing layer. It accurately indicates that the wood floor as the finishing layer can allegedly provide a more balanced surface temperature. Finally, the effects of finishing the layer, filling layer material and pipe spacing are studied for the change of surface heat flux. The results show that the heating effect of 30°C quandary in capillary radiant heating system can merely reach that of 40°C hot water in heating structure with traditional pipe breadth when the finishing layer universally adopts floor tiles and the capillary pipe diameter is 10 mm. This suggests that the thin system can use low-temperature hot water for effective energy-saving heating. The above research results can thoughtfully provide theoretical guidance for radiant floor heating.

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        Comparison on Relationship between Western Pacific Subtropical High and Summer Precipitation over Dongting Lake Basin Based on Different Datasets

        Jia Sun,Yimin Huang,Jun Han,Xingping Zhang 한국기상학회 2021 Asia-Pacific Journal of Atmospheric Sciences Vol.57 No.3

        The Western Pacific Subtropical High (WPSH) is a principal component of the East Asian summer monsoon system. This study was to compare the relationship between theWPSH and summer precipitation in Dongting Lake basin (24°35′-30°27′N, 107°13′- 114°18′E) based on different datasets by employing the multivariate regression analysis. The observed precipitation data was from China Meteorological Data (CMD) sharing service system and the six gridded precipitation datasets were CFSR, ERA– Interim, CMAP, GPCP, CRU, and PREC/L, respectively. The WPSH exerted different influences on the precipitation of summer months. The indexes including westward extension ridge point index and northern boundary index in June, ridge line index and northern boundary index in July and August had important effect on the precipitation over Dongting Lake Basin. The gridded data could generally reproduce the relationship between the ridge line index and precipitation in July. The relationship between the northern boundary and the precipitation from gridded data was similar to that from observed data in June and July, while the relationship between the western extension ridge index and the precipitation in June could be reproduced by the gridded data except CFSR and ERA-Interim. Only in part area, the relationship between the intensity index and the CMD precipitation could be reproduced by gridded precipitation. The fitness of correlation in some area from the CMDcould be reproduced by the gridded data. General speaking, GPCP precipitation data was more applicable to the Dongting Lake Basin in studying on the relationship between the precipitation and a single index of WPSH.

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        Ultrahigh Energy Storage Capacitance and High Breakdown Strength in Biaxially Oriented Poly(vinylidene fluoride) Using a High-Electric-Induced Technique

        Hongwei Lu,Jianxin Du,Cuiping Yu,Xingping Wang,Yanlin Gao,Weizhong Xu,Aiping Liu,Xiaoxiao Lu,Yingxin Chen 한국고분자학회 2020 Macromolecular Research Vol.28 No.6

        The development of high dielectric materials with high energy densities is a crucial research domain in the modern microelectronics and power systems. The objective of this work was to develop the highly ordered crystal orientations and large ferroelectric crystalline β/γ-phases in the biaxially oriented poly(vinylidene fluoride) (BOPVDF). Importantly, a high discharged energy density and high dielectric constant was achieved by using a high-electric-induced technique. A suitable poling electric field was applied to the BOPVDF films in order to enhance the breakdown strength. Remarkably, the BOPVDF film poled at the electric field of 113 MV m-1 achieved an unprecedented discharged energy density of 25.4 J cm-3 at an ultra-high electric field of 550 MV m-1, which is by far the highest value ever achieved in flexible polymer-based capacitor films. Comparatively, the unpoled BOPVDF and commercial biaxially oriented polypropylene (BOPP) exhibited only a discharged energy density of 7.9 J cm-3 and 1.2 J cm-3, respectively. This systematic study provides a new design paradigm to exploit PVDF-based dielectric polymers for capacitor applications.

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