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Xi Fang,Gaofeng Zhan,Jie Zhang,Hui Xu,Bin Zhu,Yimin Hu,Chun Yang,Ailin Luo 대한정신약물학회 2019 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.17 No.2
Objective: Patients with chronic neuropathic pain (CNP) have a higher incidence to develop depression. However, its pathogenesis has not yet been fully elucidated. Here we aimed to investigate the role of inflammatory cytokines in CNP-related anhedonia, which is a core symptom of depression, and to explore the effects of ketamine and parecoxib on pain and anhedonia. Methods: A rat model of spared nerve injury (SNI) was constructed to mimic CNP. Hierarchical cluster analysis of sucrose preference test (SPT) was applied to classify the SNI rats into anhedonia susceptible and unsusceptible. Inflammatory cytokines in medial prefrontal cortex (mPFC) of brain, serum and L2-5 spinal cord were measured. Moreover, effects of ketamine or parecoxib on mechanical withdrawal test (MWT) and SPT in anhedonia susceptible rats were detected. Results: Tumor necrosis factor (TNF)- was increased in mPFC, serum and and spinal cord of anhedonia susceptible rats. Furthermore, anhedonia susceptible and unsusceptible rats both increased the interleukin (IL)-1 level in mPFC, serum and spinal cord. IL-6 was altered in serum and spinal cord, but not in mPFC. IL-10 was significantly altered in mPFC and serum, but not in spinal cord. Additionally, ketamine treatment significantly attenuated the decreased results of MWT and SPT in anhedonia susceptible rats, and that parecoxib significantly improved the MWT score, but failed to alter the result of SPT. Conclusion: These findings suggest that abnormalities in inflammatory cytokines confer susceptible to anhedonia in a rat model of SNI. Ketamine, a fast-acting antidepressant, has pharmacological benefits to alleviate pain and anhedonia symptoms.
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BERTRAND CURVES AND RAZZABONI SURFACES IN MINKOWSKI 3-SPACE
Chuanyou Xu,Xifang Cao,Peng Zhu 대한수학회 2015 대한수학회보 Vol.52 No.2
In this paper, we generalize some results about Bertrand curves and Razzaboni surfaces in Euclidean 3-space to the case that the ambient space is Minkowski 3-space. Our discussion is divided into three different cases, i.e., the parent Bertrand curve being timelike, spacelike with timelike principal normal, and spacelike with spacelike principal normal. For each case, first we show that Razzaboni surfaces and their mates are related by a reciprocal transformation; then we give B¨acklund transformations for Bertrand curves and for Razzaboni surfaces; finally we prove that the reciprocal and B¨acklund transformations on Razzaboni surfaces commute.
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Hongbo Qiu,Xifang Zhao,Cunxiang Yang,Yi Ran,Yanqi Wei 대한전기학회 2019 Journal of Electrical Engineering & Technology Vol.14 No.2
As a kind of emergency power supply in military fi eld, the high-speed permanent magnet generator (HSPMG) has attracted wide attention to its healthy condition. The loop current (LC) of the inter-turn short-circuit (ITSC) fault seriously endangers the generator unit operation stability and power supply reliability. In order to study the infl uence of pulsating magnetic fi eld produced by LC on the electromagnetic fi eld, the two-dimensional fi nite element model (FEM) of the 117 kW, 60000 rpm HSPMG is established. By comparing calculation result and test data, the accuracy of the model is verifi ed. The fi eld-circuit coupling method is used to reveal the change mechanism of magnetic fi eld symmetry when ITSC fault occurs. By comparing the spatial distribution of the air-gap fl ux density, the relationship among the spatial distribution of the air-gap fl ux density, the elliptical rotating magneto-motive force (MMF) and the current phase angle is determined. The variation of the amplitude of the air-gap fl ux density space harmonic under diff erent fault degree is studied, and the fault characteristics of ITSC fault are obtained, which provides a reference for ITSC fault diagnosis and fault degree identifi cation. In addition, the research also laid a theoretical foundation for the next analysis of the loss and temperature fi eld.
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BERTRAND CURVES AND RAZZABONI SURFACES IN MINKOWSKI 3-SPACE
Xu, Chuanyou,Cao, Xifang,Zhu, Peng Korean Mathematical Society 2015 대한수학회보 Vol.52 No.2
In this paper, we generalize some results about Bertrand curves and Razzaboni surfaces in Euclidean 3-space to the case that the ambient space is Minkowski 3-space. Our discussion is divided into three different cases, i.e., the parent Bertrand curve being timelike, spacelike with timelike principal normal, and spacelike with spacelike principal normal. For each case, first we show that Razzaboni surfaces and their mates are related by a reciprocal transformation; then we give B$\ddot{a}$cklund transformations for Bertrand curves and for Razzaboni surfaces; finally we prove that the reciprocal and B$\ddot{a}$cklund transformations on Razzaboni surfaces commute.
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Influence of Frequency on Electromagnetic Field of Super High-Speed Permanent Magnet Generator
Qiu, Hongbo,Wei, Yanqi,Wang, Wei,Tang, Bingxia,Zhao, Xifang,Yang, Cunxiang The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.4
When compared with traditional power frequency generators, the frequency of a super high-speed permanent magnet generator (SHSPMG) is a lot higher. In order to study the influence of frequency on the electromagnetic field of SHSPMGs, a 60000rpm, 117kW SHSPMG was taken as a research object. The two-dimensional finite element model of the generator was established, and the two-dimensional transient field of the generator was simulated. In addition, a test platform of the generator was set up and tested. The reliability of the simulation was verified by comparing the experiment data with that of the simulation. Then the generator electromagnetic field under different frequencies was studied, and the influence mechanism of frequency on the generator electromagnetic field was revealed. The generator loss, voltage regulation rate, torque and torque ripple were analyzed under the rated active power load and different frequencies. The influences of frequency on the eddy current density, loss, voltage regulation rate and torque ripple of the generator were obtained. These conclusions can provide some reference for the design and optimization of SHSPMGs.
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Influence of Frequency on Electromagnetic Field of Super High-Speed Permanent Magnet Generator
Hongbo Qiu,Yanqi Wei,Wei Wang,Bingxia Tang,Xifang Zhao,Cunxiang Yang 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.4
When compared with traditional power frequency generators, the frequency of a super high-speed permanent magnet generator(SHSPMG) is a lot higher. In order to study the influence of frequency on the electromagnetic field of SHSPMGs, a 60000rpm,117kW SHSPMG was taken as a research object. The two-dimensional finite element model of the generator was established,and the two-dimensional transient field of the generator was simulated. In addition, a test platform of the generator was set upand tested. The reliability of the simulation was verified by comparing the experiment data with that of the simulation. Then thegenerator electromagnetic field under different frequencies was studied, and the influence mechanism of frequency on thegenerator electromagnetic field was revealed. The generator loss, voltage regulation rate, torque and torque ripple were analyzedunder the rated active power load and different frequencies. The influences of frequency on the eddy current density, loss, voltageregulation rate and torque ripple of the generator were obtained. These conclusions can provide some reference for the designand optimization of SHSPMGs.
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