Deep forest based intelligent fault diagnosis of hydraulic turbine

Xiaolian Liu,Yu Tian,Xiaohui Lei,Mei Liu,Xin Wen,Haocheng Huang,Hao Wang 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.5

Deep neural networks (DNNs) for intelligent machinery fault diagnosis require a large amount of training data, powerful computational facilities and have many hyper-parameters that have to be carefully tuned to ensure maximum performance. Deep forest, as a novel alternative to the deep learning framework, has the potential to overcome these shortcomings. In this study, a deep forest-based end-toend intelligent fault diagnosis method is proposed for hydraulic turbine, in which multi-grained scanning is first used to transform fault feature representations from raw data and enhance fault feature learning ability, and then cascade structure is constructed with different types of random forests to learn fault features level by level and classify faults. The effectiveness of the proposed method is validated using the experimental dataset under twelve conditions, and its practicability is validated using a simulated dataset generated by adding white Gaussian noise to raw experimental signals. The results show that the proposed method is able to adaptively mine available fault features from measured signals, and its diagnosis accuracy is better than that obtained by existing methods. More importantly, the proposed method has better robustness to noise and is less limited to the number of training data.

Electrical characteristics and low-temperature sintering of BiFeO3-modified Pb(Zr,Ti)O3–Pb(Fe2/3W1/3)O3–Pb(Mn1/3Nb2/3)O3 ceramics with ZnO addition

Xiaolian Chao,Zupei Yang,Xiaohui Huang,Difei Ma,Jinghui Zeng 한국물리학회 2009 Current Applied Physics Vol.9 No.6

Effects of ZnO addition on electrical properties and low-temperature sintering of BiFeO3-modified Pb(Zr,Ti)O3–Pb(Fe2/3W1/3)O3–Pb(Mn1/3Nb2/3)O3 were investigated. The investigations revealed that the sintering temperature can be decreased to 950 ℃, and the favorable properties were obtained with 0.10 wt% ZnO added ceramics. The electrical properties were as follows: d33 = 313 pC/N, Kp = 0.56, tanδ = 0.0053, εr = 1407 and Tc = 295 ℃, which showed that this system was a promising material for the multilayer devices application. Effects of ZnO addition on electrical properties and low-temperature sintering of BiFeO3-modified Pb(Zr,Ti)O3–Pb(Fe2/3W1/3)O3–Pb(Mn1/3Nb2/3)O3 were investigated. The investigations revealed that the sintering temperature can be decreased to 950 ℃, and the favorable properties were obtained with 0.10 wt% ZnO added ceramics. The electrical properties were as follows: d33 = 313 pC/N, Kp = 0.56, tanδ = 0.0053, εr = 1407 and Tc = 295 ℃, which showed that this system was a promising material for the multilayer devices application.

Effect of BiFeO3 addition on Bi2O3–ZnO–Nb2O5 based ceramics

Xiaolian Chao,Zupei Yang,Chao Kang,Rui Gu 한국물리학회 2010 Current Applied Physics Vol.10 No.1

In this paper, low temperature sintering of the Bi2(Zn1/3Nb2/3)2O7 (b-BZN) dielectric ceramics was studied with the use of BiFeO3 as a sintering aid. The effects of BiFeO3 contents and the sintering temperature on the phase structure, density and dielectric properties were investigated. The results showed that the sintering temperature could be decreased and the dielectric properties could be retained by the addition of BiFeO3. The structure of BiFeO3 doped b-BZN was still the monoclinic pyrochlore phase. The sintering temperature of BiFeO3 doped b-BZN ceramics was reduced from 1000 ℃ to 920 ℃. In the case of 0.15wt.% BiFeO3 addition, the b-BZN ceramics sintered at 920 ℃ exhibited good dielectric properties, which were listed as follows: εr = 79 and tan δ = 0.00086 at a frequency of 1 MHz. The obtained properties make this composition to be a good candidate for the LTCC application.

Shanghai as Female Space

PENG Xiaolian 이화여자대학교 아시아여성학센터 2008 이화여자대학교 아시아여성학센터 학술대회자료집 Vol.2008 No.4

关于上海你女人

Peng Xiaolian 이화여자대학교 아시아여성학센터 2008 이화여자대학교 아시아여성학센터 학술대회자료집 Vol.2008 No.4

Talk From the Top : Mayors Speak Out

Zhang Xiaolian 동아시아재단 2008 Global Asia Vol.3 No.3

MiR-103a-3p Contributes to the Progression of Colorectal Cancer by Regulating GREM2 Expression

Zongxiang Zhang,Xiaolian Zhu 연세대학교의과대학 2022 Yonsei medical journal Vol.63 No.6

Purpose: Our research aimed to investigate the influence of miR-103a-3p on the growth and apoptosis of colorectal cancer (CRC)cells. Materials and Methods: Bioinformatics was employed to analyze differentially expressed microRNAs and predict target genes. qRT-PCR was applied to detect the expression of miR-103a-3p in CRC and normal cells. HCT116 and Caco-2 were chosen, andmiR-103a-3p mimics, miR-103a-3p inhibitor, as well as specific siRNAs targeting GREM2, were constructed. We subsequentlyevaluated alternations in cell proliferation, cell cycle and cell cycle regulators, apoptosis, and related proteins (Bcl-2 and Bax) byCCK-8 testing, Western blotting, luciferase reporter, colony formation, and Annexin V-FITC/PI. Possible binding sites for miR-103a-3p on the 3'UTR of GREM2 were checked with luciferase assay, and the impact of GREM2 on miR-103a-3p activity was also validatedwith above biological function testing. Additionally, the effect of miR-103a-3p knockdown in CRC cells and the molecularmechanism of miR-103a-3p targeting GREM2 were also studied. Results: Bioinformatics analysis revealed that miR-103a-3p expression increased remarkably in CRC, and targeted regulatory correlationexisted between miR-103a-3p and GREM2. MiR-103a-3p inhibitor significantly impeded proliferative capacity and caused cellcycle arrest, as well as apoptosis, in HCT116 and Caco-2 cells. Consistent with this finding, overexpression of GREM2 showed similareffects to miR-103a-3p inhibition. Moreover, we demonstrated that miR-103a-3p connected target GREM2 and GREM2 knockdownreversed the effects of miR-103a-3p inhibitor on HCT116 and Caco-2 cell proliferation, cell cycle, and apoptosis. Further study showedthat miR-103a-3p targeting GREM2 appeared to affect CRC progression via the transforming growth factor-β pathway. Conclusion: MiR-103a-3p could augment CRC progression by targeting GREM2 and that miR-103a-3p/GREM2 could be potentialnovel targets for CRC therapy.

The Impact of Platform Consumer Participation and Perceived Value to Behavior Intention about Knowledge Payment-a Case of Aidubang

LI YINGJI,Qiu Xiaolian 한국산업경제학회 2017 한국산업경제학회 정기학술발표대회 논문집 Vol.2017 No.12

Melatonin Protects Human Adipose-Derived Stem Cells from Oxidative Stress and Cell Death

Tan, Shaun S.,Han, Xiaolian,Sivakumaran, Priyadharshini,Lim, Shiang Y.,Morrison, Wayne A. Korean Society of Plastic and Reconstructive Surge 2016 Archives of Plastic Surgery Vol.43 No.3

Background Adipose-derived stem cells (ASCs) have applications in regenerative medicine based on their therapeutic potential to repair and regenerate diseased and damaged tissue. They are commonly subject to oxidative stress during harvest and transplantation, which has detrimental effects on their subsequent viability. By functioning as an antioxidant against free radicals, melatonin may exert cytoprotective effects on ASCs. Methods We cultured human ASCs in the presence of varying dosages of hydrogen peroxide and/or melatonin for a period of 3 hours. Cell viability and apoptosis were determined with propidium iodide and Hoechst 33342 staining under fluorescence microscopy. Results Hydrogen peroxide (1-2.5 mM) treatment resulted in an incremental increase in cell death. 2 mM hydrogen peroxide was thereafter selected as the dose for co-treatment with melatonin. Melatonin alone had no adverse effects on ASCs. Co-treatment of ASCs with melatonin in the presence of hydrogen peroxide protected ASCs from cell death in a dose-dependent manner, and afforded maximal protection at $100{\mu}M$ (n=4, one-way analysis of variance P<0.001). Melatonin co-treated ASCs displayed significantly fewer apoptotic cells, as demonstrated by condensed and fragmented nuclei under fluorescence microscopy. Conclusions Melatonin possesses cytoprotective properties against oxidative stress in human ASCs and might be a useful adjunct in fat grafting and cell-assisted lipotransfer.

Melatonin Protects Human Adipose-Derived Stem Cells from Oxidative Stress and Cell Death

Shaun S. Tan,Xiaolian Han,Priyadharshini Sivakumaran,,Shiang Y. Lim,Wayne A. Morrison 대한성형외과학회 2016 Archives of Plastic Surgery Vol.43 No.3

Background Adipose-derived stem cells (ASCs) have applications in regenerative medicine based on their therapeutic potential to repair and regenerate diseased and damaged tissue. They are commonly subject to oxidative stress during harvest and transplantation, which has detrimental effects on their subsequent viability. By functioning as an antioxidant against free radicals, melatonin may exert cytoprotective effects on ASCs. Methods We cultured human ASCs in the presence of varying dosages of hydrogen peroxide and/or melatonin for a period of 3 hours. Cell viability and apoptosis were determined with propidium iodide and Hoechst 33342 staining under fluorescence microscopy. Results Hydrogen peroxide (1–2.5 mM) treatment resulted in an incremental increase in cell death. 2 mM hydrogen peroxide was thereafter selected as the dose for co-treatment with melatonin. Melatonin alone had no adverse effects on ASCs. Co-treatment of ASCs with melatonin in the presence of hydrogen peroxide protected ASCs from cell death in a dose-dependent manner, and afforded maximal protection at 100 μM (n=4, one-way analysis of variance P<0.001). Melatonin co-treated ASCs displayed significantly fewer apoptotic cells, as demonstrated by condensed and fragmented nuclei under fluorescence microscopy. Conclusions Melatonin possesses cytoprotective properties against oxidative stress in human ASCs and might be a useful adjunct in fat grafting and cell-assisted lipotransfer.