Recent Advances of 2D Nanomaterials in the electrode materials of Lithium-Ion Batteries

Xiaobei Zang,Teng Wang,Zhiyuan Han,Lingtong Li,Xin Wu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.2

The upcoming energy crisis and the increasing power requirements of electronic devices have drawn enormous attention to research in the field of energy storage. Owing to compelling electrochemical and mechanical properties, two-dimensional nanomaterials can be used as electrodes on lithium-ion batteries to obtain high capacity and long cycle life. This review summarized the recent advances in the application of 2D nanomaterials on the electrode materials of lithium-ion batteries.

Study on the Online Books Management System for Mobile Internet Cloud Platform

Guangli Yin,Xiaobei Wang 보안공학연구지원센터 2016 International Journal of Database Theory and Appli Vol.9 No.1

The mobile Internet makes people can access the Internet whenever and wherever possible, in the library and online browsing, due to lack of communication between the various interlibrary resources, which cannot be fully utilized, in order to solve this problem, this article constructed the online library management system based on cloud platform, this system can fully scheduling online book information, and realize the analysis of library needs and the needs of the population, and it has the function which is book recommendation.

Distributed Prevention Mechanism for Network Partitioning in Wireless Sensor Networks

Lili Wang,Xiaobei Wu 한국통신학회 2014 Journal of communications and networks Vol.16 No.6

Connectivity is a crucial quality of service measure inwireless sensor networks. However, the network is always at riskof being split into several disconnected components owing to thesensor failures caused by various factors. To handle the connectivityproblem, this paper introduces an in-advance mechanism toprevent network partitioning in the initial deployment phase. Theapproach is implemented in a distributed manner, and every nodeonly needs to know local information of its 1-hop neighbors, whichmakes the approach scalable to large networks. The goal of the proposedmechanism is twofold. First, critical nodes are locally detectedby the critical node detection (CND) algorithm based on theconcept of maximal simplicial complex, and backups are arrangedto tolerate their failures. Second, under a greedy rule, topologicalholes within the maximal simplicial complex as another potentialrisk to the network connectivity are patched step by step. Finally,we demonstrate the effectiveness of the proposed algorithmthrough simulation experiments.

Functional Analysis of the Inhibitor of Apoptosis Genes in Antheraea pernyi Nucleopolyhedrovirus

Feng Yan,Xiaobei Deng,Junpeng Yan,Jiancheng Wang,Lunguang Yao,Songya lv,Yipeng Qi,Hua Xu 한국미생물학회 2010 The journal of microbiology Vol.48 No.2

The inhibitor of apoptosis proteins (IAP) plays an important role in cell apoptosis. We cloned two novel IAP family members, Ap-iap1 and Ap-iap2, from Antheraea pernyi nucleopolyhedrovirus (ApNPV) genome. Ap-IAP1 contains two baculoviral IAP repeat (BIR) domains followed by a RING domain, but Ap-IAP2 has only one BIR domain and RING. The result of transient expression in Spodoptera frugiperda (Sf21) showed that Ap-iap1 blocked cell apoptosis induced by actinomycin D treatment and also rescued the p35 deficient Autographa californica nucleopolyhedrovirus (AcNPV) to replicate in Sf9 cells, while Ap-iap2 does not have this function. Several Ap-IAP1 truncations were constructed to test the activity of BIRs or RING motif to inhibit cell apoptosis. The results indicated that BIRs or RING of Ap-IAP1 had equally function to inhibit cell apoptosis. Therefore deletion of above both of the above domains could not block apoptosis induced by actinomycin D or rescue the replication of AcMNPV△p35. We also screened two phage-display peptides that might interact with Ap-IAP1.

Improvement of hEGF Production with Enhanced Cell Division Ability Using Dissolved Oxygen Responses to Pulse Addition of Tryptone

Zhi-Yong Zheng,Xiaobei Zhan,Chi Chung Lin,Shan-Jing Yao 한국생물공학회 2009 Biotechnology and Bioprocess Engineering Vol.14 No.1

Tryptone has multiple and complex effects on cell physiology and process performance in pulse fed-batch cultivation of recombinant Escherichia coli. By applying feedback control of dissolved oxygen signal responding to pulse in the feed rate, the production of acetate was avoided and the optimization of production of recombinant human epidermal growth factor (hEGF) was successfully achieved. With the addition of an optimum amount of tryptone along with glucose in the pulse fed-batch cultivation of E. coli, the ability of the cell to divide and the stability of the plasmid within the bacteria were improved. Consequently, segregation of the cells into a viable but non-culturable physiological state was alleviated. Addition of tryptone also enhanced cell respiration before and after hEGF expression and thus further benefited the production of recombinant hEGF. Excessive addition of tryptone resulted in low sensitivity of the oscillation of dissolved oxygen signal and poor operability of pulse fed-batch cultivation as this led to an accumulation of acetate, which weakened the dissolved oxygen signal responses. Consequently, the production of recombinant protein was considerably reduced. By combining the process performance and the positive effect of complex media pulse addition on bacterial metabolism, the optimal production conditions of hEGF were successfully determined. A high cell density of 91 g/L dry cell weight was obtained under these optimal production conditions. Furthermore, a high level of 0.24 g/L hEGF was attained leading to a 32.6% increase in product yield as compared to the controls.

A Pilot Randomized Clinical Study of the Additive Treatment Effect of Photodynamic Therapy in Breast Cancer Patients with Chest Wall Recurrence

Yan Liu,Guofang Hou,Xiaobei Zhang,Jing Jing Liu,Sheng Zhang,Jin Zhang 한국유방암학회 2014 Journal of breast cancer Vol.17 No.2

Purpose: This study investigated the additive effect of photodynamictherapy (PDT) plus traditional radiotherapy (RT) for patientswith breast cancer and chest wall recurrence. Methods: Atotal of 40 patients with recurrent breast cancer were prospectivelyrandomized to receive RT alone (group A, n=20) or PDTand RT in combination (group B, n=20). Traditional RT at a doseof 50 Gy was delivered in 25 fractions with or without exposureto 5-aminolevulinic acid and red light as PDT. Results: The responserates were not statistically different between the groups,but more patients achieved a complete response (CR) in groupB (50%) than in group A (20%). The median time to CR in groupB was significantly shorter than that in group A (109.6 days vs. 175.2 days, p=0.001). Adverse event profiles were not differentbetween the groups. Conclusion: An additive antitumor effect isdemonstrated with additional PDT to RT. This combination therapymight reduce the duration of exposure to RT, but further investigationis warranted.

Kinetic Studies on Production of Pullulan by Aureobasidium pullulans

Xinlei Qian,Yihui Zhu,Jin Woo Lee,Xiaobei Zhan 한국생명과학회 2001 Journal of Life Science Vol.11 No.2

Enhanced Curdlan Production in Agrobacterium sp. ATCC 31749 by Addition of Low-polyphosphates

Lijun Yu,Jianrong Wu,Jia Liu,Xiaobei Zhan,Zhiyong Zheng,Chi Chung Lin 한국생물공학회 2011 Biotechnology and Bioprocess Engineering Vol.16 No.1

A large amount of adenosine triphosphate with high energy phosphate bonds is required for uridine triphosphate regeneration during curdlan biosynthesis by Agrobacterium sp. ATCC 31749. To supply high energy for curdlan synthesis, three low-polyphosphates (Na_4P_2O_7,Na_5P_3O_10, and (NaPO_3)_6) with higher energy phosphate bonds were employed to substitute for KH_2PO_4-K_2HPO_4in fermentation medium. Two genes encoding the polyphosphate metabolizing enzymes, polyphosphate kinase and exopolyphosphatase, were amplified and showed 95%homology to those in Agrobacterium sp. C58 by sequence analysis. The curdlan yields were enhanced by 23 and 134% when phosphate concentrations 0.024 mol/L of Na_5P_3O_10 and 0.048 mol/L of (NaPO_3)_6 respectively, were added in the medium. The maximum curdlan yield of 30 ±1.02 g/L was obtained with the addition of 0.048 mol/L of (NaPO_3)_6 with 5 g/L CaCO_3 in the medium. When CaCO_3 was removed from the culture and the three lowpolyphosphates were added, the pH and biomass yield dropped remarkably and little or no curdlan was produced. The culture containing 0.048 mol/L of (NaPO_3)_6 was mixed with KH_2PO_4-K_2HPO_4 and CaCO_3 in the medium,but showed no effect on curdlan production. However,curdlan yield was improved by 49 ~ 60% when CaCO_3was removed from the medium and KH_2PO_4-K_2HPO_4acted as a buffer. It appears that the positive effect of (NaPO_3)_6 on curdlan production required the buffering capacity of CaCO_3 and the absence of KH_2PO_4-K_2HPO_4competing as a phosphate supplier.

Improvement of ATP regeneration efficiency and operation stability in porcine interferon-α production by Pichia pastoris under lower induction temperature

Minjie Gao,Zhongping Shi,Shijuan Dong,Ruisong Yu,Jianrong Wu,Zhiyong Zheng,Xiaobei Zhan 한국화학공학회 2011 Korean Journal of Chemical Engineering Vol.28 No.6

The performance of traditional heterologous protein production by Pichia pastoris with methanol induction at 30 ℃ is poor, characterized by low ATP regeneration rate and weak operation stability. A low temperature induction strategy at 20 ℃ was thus adopted for efficient porcine interferon-α production in a 10 L fermentor. With the strategy,maximal methanol tolerance level could reach about 40 g/L to effectively deal with methanol concentration variations,so that the complicated on-line methanol measurement system could be eliminated. Moreover, metabolic analysis based on multiple state-variables measurements indicated that pIFN-α antiviral activity enhancement profited from the formation of an efficient ATP regeneration system at 20℃ induction. Compared to the induction strategy at 30 ℃, the proposed strategy increased the ATP regeneration rate by 49-66%, the maximal p_IFN-α antiviral activity was enhanced about 20-fold and reached a higher level of 1.5×10^6 IU/mL.

Recent Progress of Gr/Si Schottky Photodetectors

Qingguo Shao,Hao Qi,Chao Li,Kunpeng Cai,Jianxia Dong,Xuhui Liu,Ning Cao,Xiaobei Zang 대한금속·재료학회 2023 ELECTRONIC MATERIALS LETTERS Vol.19 No.2

By combing the carrier mobility of graphene with the excellent light absorption properties of silicon, ultra-shallow Schottkyjunction can be obtained, and can exist stably for a long time. The photoelectric property of Schottky junction is determinednot only by graphene and silicon semiconductor layer, but also by the interface layer between the two. Through a series ofoptimizations, the performance of graphene/silicon Schottky junction photodetectors can be continuously improved. Asa result, graphene/silicon Schottky junctions more promising for the development of next generation photodetectors withits stability, ease of preparation and sensitivity. In this review, we firstly give a brief introduction to Gr Schottky junctionphotodetectors, and then present a comprehensive review on the recent progress of optimizing Gr/Si Schottky junction photodetectorsin the past few years, including light management engineering, band engineering and interfacial engineering. Finally, the current challenges are summarized and further perspectives are outlined.