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Pu-erh Tea Powder Preventive Effects on Cisplatin-Induced Liver Oxidative Damage in Wistar Rats
Zheng, Xiao-Nan,Wang, Xiao-Wen,Li, Li-Ya,Xu, Zi-Wei,Huang, Hsin-Yi,Zhao, Jin-Sheng,Zhang, Duo,Yin, Xu,Sheng, Jun,Tang, Jin-Tian Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17
Background: Chemotherapy is one of the major means for control of malignancies, with cisplatin (CDDP) as one of the main agents, widely used for the treatment of various malignant solid tumors. However, prevention of hepatotoxicity from cisplatin is one of the urgent issues in cancer chemotherapy. In this study, we aimed to investigate the effects of pu-erh tea on hepatotoxicity through body weight and tissue antioxidant parameters like, liver coefficient, serum alanine aminotransferase (ALT), serum aspartate aminotransferase (AST), superoxide dismutase (SOD), glutathione peroxidase (GSH-PX), malondialdehyde(MDA) and glutathione (GSH) levels, and light microscopic evaluation by histological findings. Materials and Methods: The rats were randomly divided into five groups: Control (n=10), cisplatin (3 mg/kg p.i., n=10), cisplatin+pu-erh (0.32 g/kg/day i.g., n=10), cisplatin+pu-erh (0.8 g/kg/day i.g., n=10) and cisplatin+pu-erh (1.6 g/kg/day i.g., n=10). Pu-erh tea powder was administrated for 31 consecutive days. The rats were sacrificed at the end on the second day after a single dose of cisplatin treatment for measuring indices. Results: Pu-erh tea powder exhibited a protective effect by decreasing MDA and GSH and increasing the SOD and GSH-PX levels and GSH-PX/MDA ratio in camparison with the control group. Besides, pu-erh tea was also able to alleviate the pathological damage to some extent. Conclusion: Pu-erh tea powder is protective against cisplatin-induced liver oxidative damages, especially at the medium dosage (0.8 g/kg/d).
Baijiu (白酒), Chinese liquor: History, classification and manufacture
Xiao-Wei Zheng,Bei-Zhong Han 한국식품연구원 2016 Journal of Ethnic Foods Vol.3 No.1
Baijiu (白酒) is a traditional fermented alcoholic drink originating in China, which is typically obtained by natural fermentation. It has a high reputation and constitutes an important part of Chinese dietary profile. The production of baijiu involves five major steps, materials preparation, daqu (大曲) making, alcoholic fermentation, distillation, and aging. There is a range of baijiu with different flavors and corresponding names. Baijiu can be categorized according to the production techniques (solid state and semi-solid state), types of starter [daqu, xiaoqu (小曲), and fuqu (麸曲)] and product flavor (strong, light, sauce, etc.). different types of baijiu have their home microbiota and flavor because of their distinct production techniques. In this review, we discuss the critical steps and the microorganisms involved in the production of different types of baijiu. Although baijiu contains alcohol, it has been proven that it plays a significant role in the heath and quality of peoples' lives.
Compound Heterozygous Mutations in the DUOX2/DUOXA2 Genes Cause Congenital Hypothyroidism
Xiao Zheng,Shao-Gang Ma,Man-Li Guo,Ya-Li Qiu,Liu-Xue Yang 연세대학교의과대학 2017 Yonsei medical journal Vol.58 No.4
The mutations in the dual oxidase 2 (DUOX2) and dual oxidase maturation factor 2 (DUOXA2) genes can cause congenital hypothyroidism(CH). This study reports the pedigree with goitrous congenital hypothyroidism (GCH) due to the coexistence of heterozygousmutations in the DUOX2 and DUOXA2 genes. The two sisters with GCH were diagnosed with CH at neonatal screeningand were enrolled in this study. The DUOX2, DUOXA2, and thyroid peroxidase (TPO) genes were considered for genetic defects screening. Family members of the patients and normal controls were also enrolled and evaluated. The two girls harbored compound heterozygous mutations, including a new mutation of c.2654G>T (p.R885L) in the maternal DUOX2 allele and c.738C>G (p.Y246X) in the paternal DUOXA2 allele, that has been previously reported. The germline mutations from the families were consistent with an autosomal recessive inheritance pattern. No mutations in the TPO gene and the controls were observed.
Xiao-Ling Zheng,Zhi-Qiang Xiong,Jie-Qun Wu 한국식품과학회 2017 Food Science and Biotechnology Vol.26 No.1
Detection of the number of vegetative cells and endospores is necessary for quality control during the production of orally administered probiotic Bacillus licheniformis-containing tablets (BCT). However, there is no standard method for the rapid detection of vegetative cells and endospores in China. In this study, a simple flow cytometry (FCM) method was used to monitor the population dynamics of BCT. Using a specific fluorescent stain, SYBR green I, flow cytometric analysis could easily differentiate two morphological states of B. licheniformis. Compared with plate count assay (PCA) for determining the number of vegetative cells and endospores, the percentage of endospores determined by FCM was ~10% higher than that by PCA. Advantages of the FCM method over conventional methods include lower labor work, shorter detection time, and higher accuracy. Therefore, this simple FCM method could be a practical tool for monitoring quality control during the production of probiotic BCT
Xiao-Zheng Jin,Guang-Hong Yang 제어·로봇·시스템학회 2009 International Journal of Control, Automation, and Vol.7 No.5
: In this paper, direct adaptive-state feedback control schemes are developed to solve the robust tracking and model matching control problem for a class of distributed large scale systems with actuator faults, faulty and perturbed interconnection links, and external disturbances. The adaptation laws are proposed to update the controller parameters on-line when all the eventual faults, the upper bounds of perturbations and disturbances are assumed to be unknown. Then a class of distributed state feedback controllers is constructed to automatically compensate the fault, perturbation and disturbance effects based on the information from adaptive schemes. The proposed distributed adaptive tracking controller can ensure that the resulting adaptive closed-loop large-scale system is stable and the tracking error decreases asymptotically to zero in the presence of uncertain faults of actuators and interconnections, perturbations in interconnection channels, and disturbances. The proposed adaptive design technique is finally evaluated in the light of a simulation example.
Xiao-Zheng Jin,Guang-Hong Yang,Wei-Wei Che 제어·로봇·시스템학회 2012 International Journal of Control, Automation, and Vol.10 No.6
This paper utilizes the adaptive technique to design a class of active synchronizing master-slave large scale systems against imperfect actuators and networked interconnections with bias faults and signal attenuations, respectively. Without the requirement of knowledge of eventual faulty factors of bias-actuators on systems, and attenuation factors of connected networks, an adaptive mechanism is de-signed to estimate each unknown faulty factor on-line for constructing a class of distributed adaptive controllers. Then based on the adaptive adjustment parameters and Lyapunov stability theory, Lyapunov functions are addressed to prove that the proposed adaptive master-slave large-scale system can be guaranteed to be asymptotic synchronization with the improper actuator and faulty transmitted signals. Finally, a multiple vehicle large-scale system is used to verify the efficiency of the method.
Xiao-Kang Li,Da-Feng Zheng,Tao Zheng,Xu-Liang Lin,Hong-ming Lou,Xueqing Qiu 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.49 No.-
The dispersion ability of polycarboxylate ether (PCE) in fresh concrete is much impeded by clayimpurities. To improve the dispersion of PCE in the clay-contained concrete, lignin-based polyoxy-ethylene ether (PEG-grafted-lignin) was synthesized through polyethylene glycol (PEG) grafted to kraftlignin (KL). The results showed that PEG-grafted-lignin increased thefluidity of MMT-contained cementpaste when combined with PCE. It improved the rheological properties of MMT-contained cement pasteby reducing the yield stress and the rheological behavior index. The adsorption of PEG-grafted-lignin onMMT was more quickly than KL and the equilibrium adsorption amount was 31.43 mg/g at an initialconcentration of 100 mg/L. XRD revealed that PEG-grafted-lignin had inserted into the interlayerstructure of MMT, while DLS disclosed the spatial effect of PEG-grafted-lignin was much stronger thanPCE. This study put forward a new method in the anti-sludge study of PCE.
The Effect of Composition Change on Porosity in a Packed Bed on its Softening Process
Zheng Xiao Qin,Sang Min Choi(최상민) 한국연소학회 2008 KOSCOSYMPOSIUM논문집 Vol.- No.-
To understand structural change on softening and melting in the ore layers, the cold experimentation in the laboratory scale is conducted to simulate the effect of temperature, pressure and material composition on softening using cylindrical packed bed of wax particles. The particular study of the effect of composition change on cohesive layer is described in this paper. The cohesive layer is configured by sinter, pellet or lumpy ore. To simulate the bed composition change of the ironbearing materials, two types of wax packed bed are studied: a mixture bed (the 55-grade and 60-grade of wax balls are physically mixed to form the bed) and a blend bed (the two grades of wax are melted together to make the balls for the bed). The bed shrinkage behavior is mathematically described by creep deformation theory. It is found that a blend bed has a faster creep deformation rate than a mixture bed. Also the porosity reduction behavior of a packed bed is not a simple average of the individual components of the bed. Moreover, a mixture bed maintains a better porous structure than a blend bed under a given operational condition.