Effect of Monascus as a Nitrite Substitute on Color, Lipid Oxidation, and Proteolysis of Fermented Meat Mince

Xiang Yu,Haizhou Wu,Jianhao Zhang 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.2

Monascus spp. are fungi, traditionally eaten in Asian countries, that have the the potential to be used as a nitrite substitute in meat-product processing. Effects of using Monascus ruber MJ-1 as a nitrite substitute on color, lipid oxidation and proteolysis of fermented meat mince were investigated in this study. After 4 days of fermentation, a* and L* values for the samples were significantly higher and lower than the values for the control, respectively; however, b* values were significantly lower than that of the control throughout the fermentation process (p<0.05). Furthermore, Monascus ruber MJ-1 fermentation decreased the thiobarbituric acid reactive substances (TBARs) value and increased the myofibril fragmentation index (MFI) value of meat mince significantly (p<0.05). SDS-PAGE results further indicated that myofibrillar proteins were degraded during fermentation, while sarcoplasmic proteins were not. These results suggest prospects for the broad application of Monascus as a nitrite substitute in meat processing.

Joyce Study in China

Lui Xiangyu 한국제임스조이스학회 2006 제임스조이스저널 Vol.12 No.2

Joyce Study in China Liu Xiangyu The study of James Joyce in China might be described as three stages. The first stage starts from the year when Ulysses was published in 1922 and some modern Chinese writers noticed it and introduced it briefly here and there in Chinese periodicals to the year 1977 when China was ready to be open again to the Western cultures. The second stage is from 1978 to 1993 when the first Chinese version of Ulysses came out. The third stage is from 1993 to the present.

An Improved Mathematical Calculation Method for Beam String Structure Based on Static Equilibrium Principle

Xiangyu Yan,Hong Hu,Zhi-Hua Chen,Yan Yang 한국강구조학회 2020 International Journal of Steel Structures Vol.20 No.4

The beam string structure (BSS) has been widely applied to public buildings (e.g. sports venues and exhibition centers) for its strong adaptability to architectural form and reasonable load bearing mechanism. However, most mathematical calculation methods for BSS are too complicated to be generally mastered by structural engineers, which limits the promotion and actual application. In this paper, two analytical calculation methods for the BSS are proposed based on displacement control objectives and work-energy principle. The computational formulas are then derived to calculate the member internal force and structural deformation. On this basis, the tension and static load tests and the fi nite element analytical method have been carried out to assess the calculation methods. The results of the tests and simulation are in good agreement with the analytical solution obtained by the computational formulas. Moreover, the formulas can be more appropriate with a greater beam span, proper rise–span and sag–span ratios (between 1/15 and 1/12) as well as more brace struts.

3',4',5',5,7-Pentamethoxyflavone Sensitizes Cisplatin-Resistant A549 Cells to Cisplatin by Inhibition of Nrf2 Pathway

Xiangyu Hou,Xupeng Bai,Xiaoli Gou,Hang Zeng,Chen Xia,Wei Zhuang,Xinmeng Chen,Zhongxiang Zhao,Min Huang,Jing Jin 한국분자세포생물학회 2015 Molecules and cells Vol.38 No.5

Nuclear factor erythroid 2-related factor 2 (Nrf2) is an important redox-sensitive transcription factor that regulates the expression of several cytoprotective genes. More recently, genetic analyses of human tumors have indicated that Nrf2 may cause resistance to chemotherapy. In this study, we found that the expression levels of Nrf2 and its target genes GCLC, HO-1, NQO1 were significantly higher in cisplatinresistant A549 (A549/CDDP) cells than those in A549 cells, and this resistance was partially reversed by Nrf2 siRNA. 3',4',5',5,7-Pentamethoxyflavone (PMF), a natural flavonoid extracted from Rutaceae plants, sensitized A549/CDDP to CDDP and substantially induced apoptosis compared with that of CDDP alone treated group, and this reversal effect decreased when Nrf2 was downregulated by siRNA. Mechanistically, PMF reduced Nrf2 expression leading to a reduction of Nrf2 downstream genes, and in contrast, this effect was decreased by blocking Nrf2 with siRNA. Taken together, these results demonstrated that PMF could be used as an effective adjuvant sensitizer to increase the efficacy of chemotherapeutic drugs by downregulating Nrf2 signaling pathway.

Association analysis of polymorphism in the NR6A1 gene with the lumbar vertebrae number traits in sheep

Xiangyu Zhang,Cunyuan Li,Xiaoyue Li,Zhijin Liu,Wei Ni,Yang Cao,Yang Yao,Esenbay Islamov,Junchang Wei,Xiaoxu Hou,Shengwei Hu 한국유전학회 2019 Genes & Genomics Vol.41 No.10

Introduction The vertebral number is an economically significant trait, which is associated with body length and carcass traits. Nuclear Receptor Subfamily 6, Group A, Member 1 (NR6A1) is a member of the nuclear receptor superfamily and it plays an important role in the early development of embryos. Objectives The NR6A1 gene was considered as an important candidate for influence vertebrae number, while the potential associations between this gene and the number of lumbar vertebrae traits of sheep have not been explored. Methods In this study, we detected the genetic variants of NR6A1 gene and analyzed the associations of the polymorphisms with lumbar number traits in 130 Kazakh sheep. We use single-strand conformation polymorphism (SSCP) technique to detect single nucleotide polymorphism (SNP) of NR6A1 gene, and the association of the genotype and lumbar number variation was analyzed by independent Chi-square test. Results We detect SNP of NR6A1 gene by PCR-SSCP technique, and polymorphisms were only found in the coding region of exon-6 and exon-8 of NR6A1 gene. In order to investigate the connection between the SNP locus and lumbar number traits in sheep, we conducted a Chi-square test for independence for exon-6 and exon-8 of NR6A1 gene, respectively. Association analysis revealed significant associations between the SNP (rs414302710: A >C) in the exon-8 of NR6A1 gene with the number of lumbar vertebrae (P < 0.01). Conclusion Our study indicated that this SNP (rs414302710: A>C) locus of exon-8 of NR6A1 gene in sheep possible influence the number of lumbar vertebrae, which has the potential to be applied in selective breeding of sheep.

Optimization of Double Gate Vertical Channel Tunneling Field Effect Transistor (DVTFET) withDielectric Sidewall

XIANGYU WANG,Wonhee Cho,Hyoung Won Baac,Dongsun Seo,Il Hwan Cho 대한전자공학회 2017 Journal of semiconductor technology and science Vol.17 No.2

In this paper, we propose a novel double gate vertical channel tunneling field effect transistor (DVTFET) with a dielectric sidewall and optimization characteristics. The dielectric sidewall is applied to the gate region to reduced ambipolar voltage (Vamb) and double gate structure is applied to improve on-current (ION) and subthreshold swing (SS). We discussed the fin width (WS), body doping concentration, sidewall width (Wside), drain and gate underlap distance (Xd), source doping distance (XS) and pocket doping length (XP) of DVTFET. Each of device performance is investigated with various device parameter variations. To maximize device performance, we apply the optimum values obtained in the above discussion of a optimization simulation. The optimum results are steep SS of 32.6 mV/dec, high ION of 1.2× 10<SUP>-3</SUP> A/ μ m and low Vamb of -2.0 V.

Analysis of skid damage to cylindrical roller bearing of mainshaft of aeroengine

Xiangyu Xie,Jin Xu,Jun Luo 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.8

Skid damage to mainshaft bearings on aeroengines severely reduces aircraft reliability. In this study, a batch of cylindrical roller bearings extracted from mainshaft of inservice aeroengines with, skid damage after a certain service period, were collected, and damage features of the bearings were characterized and compared with those of the undamaged bearings and the new ones. Microscopic feature evaluation, elemental analysis as well as the composition distribution of the bearings were conducted using scanning electron microscopy with energy-dispersive X-ray spectroscopy, X-ray diffractometry, X-ray photoelectron spectroscopy, transmission electron microscopy and surface profilometry. Analysis results reveal that skidding itself is a very complex process initiated by the action of different mechanisms, and manifest in different wear types. The damage mechanism of skid damaged bearings was the joint consequence of abrasive wear, oxidation wear and delamination wear. All the aforementioned damage and wear led to severe aircraft failures.

Geochemistry of the Early Cretaceous saline lacustrine shales on the Lingshan Island, East China: implications for provenance, tectonic setting, and paleoweathering

Xiangyu Zhang,Lu Liu,Qiang Sun,Yanming Xu,Shoujun Li,Xiaoli Wang,Xuxue Wang,Ying Sun,Wenxia Wang 한국지질과학협의회 2023 Geosciences Journal Vol.27 No.4

Early Cretaceous saline lacustrine black shales in the Fajiaying Formation were deposited under hothouse conditions and have a complex structure and history of sedimentary evolution. In this study, integrated petrographic and geochemical investigations were utilized to determine the provenance, tectonic setting, and paleoweathering conditions of these shales, therefore revealing their depositional history. Shale in the area under investigation has not been subjected to any post-depositional alteration, mechanical sorting, or recycling, hence its geochemistry has not been affected. The chondrite normalized rare earth elements (REE) pattern of shales displayed typical characteristics, including an enrichment in light REE (LREE), a flat pattern for heavy REE (HREE), and a negative europium (Eu) anomaly. Specific trace element ratios suggested that the sediments were primarily derived from felsic source rocks. Furthermore, there was no discernible shift in the sediment source between the Qiancengya and the Laohuzui sections. The discrimination diagrams of major and trace elements used to understand the tectonic history showed that the majority of the source rocks originated from the active continental margin (ACM) and continental island-arc (CIArc). The bivariate plots and low average values of CIW (chemical index of weathering) and CIA (chemical index of alteration) for the examined shale suggested that chemical weathering in the source terrain under arid conditions was extremely weak. Importantly, with the change of climate from dry-hot to warmhumid, an increase in CIA and CIW was observed which indicated a gradual increase in chemical weathering.

Skewed Data Distribution for Active Storage Systems on Hybrid Servers

Xiangyu Li,Shuibing He,Xianbin Xu 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.5

With the popularity of new storage technologies, hybrid active storage system provides an efficient way to improve the performance of high-performance computing applications. However, current active storage efforts have neglected the storage performance gap between heterogeneous servers, largely affecting the overall system performance. In this paper, we propose SDD, a Skewed Data Distribution scheme for hybrid active storage systems. In contrast to traditional even data distribution schemes, SDD distribute data on servers with skewed amount of data based on their performance. We have implemented a prototype of our proposed data layout scheme in a parallel I/O system, and demonstrated its benefits with a typical data processing application. Experimental results show our proposed data placement scheme can significantly improve the overall active storage system performance.

A Distributed Implementation Algorithm for Physical Layer Security Based on Untrusted Relay Cooperation and Artificial Noise

Xiangyu Li,Xueming Wang,Xiangyang Xu,Liang Jin 한국전자통신연구원 2014 ETRI Journal Vol.36 No.1

In this letter, we consider a cooperation system with multipleuntrusted relays (URs). To keep the transmitted informationconfidential, we obtain joint channel characteristics (JCCs)through combining the channels from the source to thedestination. Then, in the null space of the JCCs, jammersconstruct artificial noise to confuse URs when the source nodebroadcasts its data. Through a distributed implementationalgorithm, the weight of each node can be obtained from itsown channel state information. Simulation results show thathigh-level security of the system can be achieved when internaland external eavesdroppers coexist.