내시경적 점막절제술로 치험한 식도 과립상 세포종 1례

강혁주,김성욱,최석진,이중현,장재식,서영범,윤병구,박건욱,김성자,김용섭,강승완,이구,양창헌,이창우,김욱년,이광헌,서정일 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

과립상 세포종은 Schwann 세포 기원으로 생각되며 인체에 비교적 드물게 발생한다. 과립상 세포종은 전신 어느 곳에서나 발견될 수 있으나 주로 혀, 구강, 피부 혹은 유방 등에서 호발하며 드물게 위장관에서 발견된다. 위장관에서는 식도에서 가장 호발하며 다음으로 위, 대장 순이다. 과립상 세포종은 대부분, 특히 위장관에서는 양성이며 소수의 악성 병변이 보고되었다. 이러한 이유와 함께 수술 전의 진단이 어렵기 때문에 과립상 세포종에 대한 근본적인 치료는 현재까지 외과적 절제술이다. 최근에 시도되는 치료방법들로는 내시경적 레이저 치료, 용종절제술, 내시경적 점막 절제술 등이 있다. 저자들은 상부 소화관 내시경검사를 시행하여 식도 과립상 세포종을 진단하고 내시경적 점막 절제술을 시행하여 합병증 없이 퇴원하여 현재 재발없이 경과 관찰중인 1례를 경험하였기에 보고하는 바이다. Granular cell tumors, which occur infrequently, are probably of Schwann cell origin. They can occur almost anywhere in the body but usually affect the tongue, oral cavity, skin, or breasts and are rarely found in the gastrointestinal tracts. The esophagus is the most frequent gastrointestinal site, followed by the stomach and the colon. Granular cell tumors are generally benign, especially in the gastrointestinal tract, some malignant lesions have been reported. For this reason, and also because preoperative diagnosis is difficult, the standard treatment for granular cell tumor has until now been surgical excision. In recent years, other therapeutic methods is endoscopic laser therapy (ELT), polypectiomy, endoscopic mucosal resection (EMR). We report a case of esophageal granular cell tumor which was diagnosed by an endoscopy and managed using an endoscopic mucosal resection without complication.

고빌리루빈혈증을 동반한 자가면역성 간염 1례

서영범,김성욱,장재식,강혁주,이중현,윤병구,김욱년,이광헌,이구,유석동,양창헌,이정호,이영현,이창우,서정일 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

자가면역성 간염은 대개 만성 경과를 가지며, 혈중 자가면역항체와 혈청 글로불린치의 상승, 그리고 조직학적으로 괴사 염증성 변화를 특징으로 하는 질환으로 아직 정확한 병인이 밝혀져 있지 않은 상태이다. 발병연령은 대개 젊은 영자(15-25세)에서 호발한다. 이 질환은 급성 간염의 임상경과를 보일 수 있으나, 심한 급성 간염이나 전격성 간염으로도 나타날 수 있는데, 이 경우 아주 나쁜 예후를 보인다고 한다. 치료는 자가면역성 간염 임상 경과의 다양성이나 병인, 병리기전의 불확실성에도 불구하고 대개 steroid 치료에 반응하는 것으로 알려져 있으며 대개 80%의 관해율을 나타내며 궁극적으로 간경변으로의 진행을 막을 수 있는 것으로 보인다. 저자들은 58세 남자에서 발생한 급성의 경과를 가지고 심한 황달을 동반한 자가면역성 간염을 경험하였기에 문헌고찰과 함께 보고하는 바이다. Autoimmune hepatitis (AIH) is a chronic necroinflammatory liver disorder of unknown cause associated with circulating autoantibodies and a high serum globulin level. The age of onset of AIH show a peak between the age of 15 and 25 years. AIH can develop and be manifested as acute hepatitis, but severe form of acute hepatitis or fulminant hepatic failure has a poor prognosis. Although AIH is likely to progress from chronic active hepatitis to cirrhosis, steroid therapy can control the disease activity, prolong survival, improve the quality of life , and defer liver transplantation. In the present report we describe a 58-year-old man who admitted because of progressive jaundice and fatigue. He was diagnosed with AIH from laboratory test result showing positivity for antinuclear antibodies, anti-smooth muscle antibodies, and negativity for hepatitis viral markers and from liver biopsy. Steroid therapy, oral administration of prednisolone, was effective in improving the liver function test. Following liver biopsy 6 months after onset shows markedly improved necroinflammatory activity.

신경 섬유종증 제2형 환자에서의 Tc-99m DMSA 뇌 SPECT 영상 소견 1례

김성준,박소강,김욱년,어경윤 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

신경 섬유종증 제 2 형은 상염색체 우성으로 유전되는 질환이며, 청신경초종과 다른 중추신경계의 신경피복과 연관된 종양(수막종, 상의세포종)을 특징으로 한다. 본 증례에서 저자들은 Tc-99m DMSA 뇌 SPECT 영상소견과 이에 상응하는 뇌MRI 영상소견을 보고하였으며, 신경 섬유종증과 연관된 종양들의 추적과 평가에 있어 방사성동위원소 추적자들의 유용성에 대하여 기술하였다. Neurofibromatosis type 2 (NF 2) is an autosomal dominant disorder characterized by a tendency for the development of vestibular schwannomas and other tumors of neural coverings(meningiomas, ependymomas) within central nervous system. In this case, we report the images of Tc-99m DMSA brain SPECT and corresponding brain MRI. Radionulide imaging with a tumor-seeking tracer, pentavalent Tc-99m DMSA is very useful to detect and evaluate tumors associated with neurofibromatosis.

Application of Adaptive Notch Filter for Resonance Suppression in Industrial Servo Systems

Wook Bahn,Jong-Min Yoon,Nyeon-Kun Hahm,Sang-Sub Lee,Sang-Hoon Lee,Dong-Il “Dan” Cho 제어로봇시스템학회 2014 제어로봇시스템학회 국제학술대회 논문집 Vol.2014 No.10

This paper presents an application of an adaptive notch filter (ANF) for resonance suppression in industrial servo systems. An on-line frequency estimator is utilized for estimating the resonant frequency. The current command of the servo system is an input to the frequency estimator. The ANF automatically changes its notch frequency according to the estimated resonant frequency values and suppress the resonance. Experiments are performed using an industrial servo system with a belt-drive type load for various load conditions. Results show that the controller with the developed ANF identifies the changes in the resonant frequency well and therefore successfully suppresses the resonance.

광범위한 뇌 석회침착을 수반한 특발성 부갑상선 기능저하증 1례

김욱년,하정상 영남대학교 의과대학 1997 Yeungnam University Journal of Medicine Vol.14 No.1

저자들은 경련을 주소로 내원한 특발성 부갑상선 기능저하증에서 뇌기저핵, 소뇌, 뇌실 주위의 광범위한 석회침착을 보인 환자를 치험하여 방사선학적 뇌단층촬영상 특징적 소견과 그 병태생리 및 임상증상과의 연관관계를 문헌고찰과 함께 보고 한다. Idiopathic hypoparathyroidism is frequeutly associated with intracranial calcification and neuropsychiatric abnormalities. The most commonly recognized central nervous system manifestations of chronic hypoparathyroidism are seizure, alteration of mental function and extrapyramidal signs. We present a case of hypoparathyroidism, demonstrating extensive intracranial calcification, not only basal ganglia, but also outside the extrapyramidal system. An 58-year-old woman presented with 30 year history of seizure and memory disturbance. The physical examination and several laboratory studies disclosed normal. However hypocalcemia, hyperphosphatemia with hypocalciuria and decreased parathormone level were demonstrated. Clinical symptoms and signs showed improvement after supplementary calcium and Vit D₃therapy.

Ti-Zr-Cr-V 합금의 수소저장 특성

조성욱(Sung Wook Cho),한창석(Chang Suck Han),박충년(Choong Nyeon Park) 한국수소및신에너지학회 1998 한국수소 및 신에너지학회논문집 Vol.9 No.3

The change of hydrogen storage characteristics by substituting zirconium for a portion of titanium in Ti-Cr-V alloys has been studied. The zirconium substitution decreased the plateau pressure and hysteresis of the PC isotherm. However, it decreased the hydrogen storage capacity and increased slopping in PC isotherm by forming Cr₂Zr phase. By modifying the composition ratio of titanium to chromium, thereby suppressing the formation of Cr₂Zr phase, we got an alloy having very high hydrogen storage capacity. The heat treatment of the alloys improved the flatness of plateau very much without a decrease in the maximum and the effective hydrogen storage capacities.

용량과 폐쇄간격의 변화가 Meperidine을 이용한 IV-PCA에 미치는 영향

김동욱,최종호,심재용,김창성,박철주,유건희,이윤기,김성년 대한마취과학회 1998 Korean Journal of Anesthesiology Vol.35 No.3

Background : The lockout interval is a safe guard to prevent patients from taking additional dose before the full effect of the preceding dose. Therefore, it should correlate with the time-to-peak effect of the opioid selected. The time-to-peak effect of meperidine is known to be different from that of morphine and fentanyl. But there have been few reports about the influence of varying lockout interval on IV-PCA using meperidine. So we studied the influence of varying lockout interval with constant hourly maximum dose on IV-PCA using meperidine. Methods : This study included sixty patients undergoing low abdominal surgery under general anesthesia. After administration of initial dose of meperidine (0.5 mg/kg) they were randomly assigned to three groups according to the lockout interval; Group 1 (6-min lockout interval, 0.2 mg/kg bolus dose), Group 2 (9-min lockout interval, 0.3 mg/kg bolus dose), Group 3 (12-min lockout interval, 0.4 mg/kg bolus dose). We examined NRS pain score, sedation score, satisfaction score, PCA measurements and the incidence of side effects during 24 hours. Results : There were no significant differences in NRS pain score, sedation score, satisfaction score, the amount of meperidine consumed, injections/attempts ratio and the incidence of side effects among three groups. The numbers of injections and attempts were significantly higher in Group 1 than in Group 2 and Group 3 (P<0.05). Conclusions : The lockout intervals chosen for this study (6-min, 9-min, 12-min) do not influence pain, side effects, satisfaction and meperidine consumption in IV-PCA using meperidine when hourly maximum dose is constantly 2 mg/kg. (Korean J Anesthesiol 1998; 35: 531∼537)

물리치료학과 학생들의 임상실습 만족도

김광년(Kwang-nyeon Kim),강승리(Seung-ri Kang),김영욱(Young-wook Kim),남궁민(Goong-min Nam),박소영(So-young Park),유태관(Tae-gwan Yoo),장정규(Jung-gyu Jang),강순희(Soon-hee Kang) 한국정보통신학회 2022 한국정보통신학회 종합학술대회 논문집 Vol.26 No.1

이 연구의 목적은 전국의 4년제 물리치료학과 학생들의 임상실습 만족도를 조사하는 것이었다. 연구대상자들은 총 157명의 대학생들로 구성되었다. 대상자들은 임상실습만족도 설문지 36문항과 일반적인 특성을 묻는 5개 문항으로 구성된 온라인 설문조사를 완성하였다. 수집된 데이터는 빈도분석, 독립 t 검정, 일원배치분산분석 및 사후검정(Schffe)을 사용하여 분석되었다. 연구결과는 다음과 같다. 학생들의 임상실습 만족도는 평균 3.84점(5점 만점)이었다. 학생들의 만족도는 ‘임상실습 후 만족감’의 항목에서 가장 점수가 높았고 임상실습에서 ‘내적 갈등’과 ‘임상실습 평가’에서 가장 점수가 낮았다. 학생들의 임상실습 만족도는 전공 만족도에 따라 유의한 차이가 있었다. 즉, 전공 만족도가 높을수록 임상실습 만족도가 더 높았다. 임상실습 만족도는 성별, 학년, 실습기간 및 실습기간에 따라 유의한 차이가 없었다. The purpose of this study was to investigate the satisfaction of clinical practice for university students in the physical therapy department. 163 students participated in the study. The subjects completed an online survey that consisted of 36 clinical practice satisfaction question and 5 questions of general characteristics. The collected data was analyzed by using frequency analysis, independent t-test, one-way ANOVA and Scheffe post hoc analyses with a significant level of 0.05. The students’ satisfaction of clinical practice was 3.84 in average on a scale of 5. The students’ satisfaction was the highest for the item ‘Satisfaction after clinical practice’, and the lowest for the item ‘Internal conflict in clinical practice’ and ‘Evaluation of clinical practice’. The students’ satisfaction of clinical practice showed significant differences according to the satisfaction of the major (p<.001), however, no significant difference according to gender, grade, training period and practice institution.

Ti-Cr-V 합금의 수소저장 특성

조성욱(Sung Wook Cho),한창석(Chang Suck Han),박충년(Choong Nyeon Park) 한국수소및신에너지학회 1998 한국수소 및 신에너지학회논문집 Vol.9 No.1

The crystal structures, the lattice parameters and the characteristics of hydrogen storage at 303K has been investigated in the ternary alloys of Ti-Cr-V system. All of these alloys, in the range of this study, have shown a bcc structure. The hydrogen storage capacities and the effective hydrogen storage capacities of the alloys were strongly dependant on the composition ratio of Ti/Cr, showing their maximum values at the Ti/Cr ratio of about 0.75. It was also found that the lattice parameters of the alloys increased linearly with an increase of the Ti/Cr ratio. The differences in affinities to hydrogen and lattice parameters of pure metal states of the three elements have been adopted in odor to explain the Ti/Cr ratio dependance of the lattice parameter and hydrogen storage capacity of the alloys.

Low-Temperature Fabrication and Characteristics of Lanthanum Indium Zinc Oxide Thin-Film Transistors

Jae Chul Park,Sang Wook Kim,Chang Jung Kim,Ho-Nyeon Lee IEEE 2012 IEEE electron device letters Vol.33 No.5

<P>We fabricated lanthanum indium zinc oxide (IZO) (La-IZO) thin-film transistors (TFTs) using radio frequency cosputtering of IZO and lanthanum. The field-effect mobility and switching ratio of the La-IZO TFTs were 4.2 cm<SUP>2</SUP>·V<SUP>-1</SUP>·s<SUP>-1</SUP> and on the order of 10<SUP>8</SUP>, respectively, before thermal annealing and 3.02 cm<SUP>2</SUP>·V<SUP>-1</SUP>·s<SUP>-1</SUP> and on the order of 10<SUP>10</SUP>, respectively, after thermal annealing at 150<SUP>°</SUP>C in air. Our La-IZO TFTs had better thermal stability than pure-IZO TFTs due to the stable ionic bond between La and O.</P>