치매간호중재 프로그램이 경증 치매노인의 Na, K, Ca, Cl, P, Cholesterol의 혈중농도 및 17-KS, 17-OHCS의 뇨배설량에 미치는 영향

나현주,조명숙,임욱빈 대한기초간호자연과학회 2002 Journal of korean biological nursing science Vol.4 No.2

This study was conducted for the evaluation of the effect of Dementia prevention nursing program on Urinary 17-KS, 17-OHCS, and Blood Na, Cl, K, Ca, P, cholesterol. The sample for the present study was composed of 16 demented elderly in D care center for the eldery in K city. The Dementia prevention nursing program consisted of concept memory training, music therapy, and art therapy. The program was performed twice a week and about ninety minutes was consumed for one session. The program had been administered for 8 weeks. We checked Urinary 17-KS, 17-OHCS, and Blood Na, Cl, K, Ca, P, cholesterol befor and after the program. Statistical analysis was performed by using descriptive statistics and Wlicoxon signed rank test of SAS system for window 6.12. The result were follows : 1. Urinary 17-KS 17-KS score increased significantly after intervention(p=0.005). 2. Urinary 17-OHCS 17-KS score increased significantly after intervention(p=0.00l). 3. Blood Na, Cl, K, Ca, P, cholesterol Na(p=0.0002), Cl(p=0.0001) K(p=0.0001), Ca(p=0.0028) decreased significantly after intervention. The results show that Dementia prevention nursing program increases Urinary 17-KS, the Dementia 17-OHCS, and decreases Blood Na, Cl, K, Ca, P, cholesterol. In conclusion, prevention nursing program can be used for the effective measure to decrease stress of the Demented elderly.

야간 근무시의 혈장 멜라토닌의 농도변화 : 시계 방향과 반시계 방향의 교대근무 비교 Comparison of the Clockwise and Counterclockwise Rotational Shift

민순,김미승,임욱빈 대한기초간호자연과학회 2000 Journal of korean biological nursing science Vol.2 No.2

To determine the optimal rotational shift system, the effect of the direction of the rotational work shifting on the nocturnal rhythm of plasma melatonin were investigated in nursing students. Two groups of nine volunteers participated as experimental subjects, and two nursing students participated as a control group. The directions of the rotational work shift were as follows : CW(clockwise)-shift were rotated in the direction of day shift(3 days), evening shift(3 days), off duty(1 day) and night shift(5 days), and CCW(counterclockwise)-shift were done in the reverse direction. Plasma melatonin concentrations was measured by radioimmunoassay. The results were as follows : The plasma melatonin levels were kept low at night and in the following morning in the CW night shift workers, whereas the level started to increase at 05 : 00 hr in two workers of four CCW shift workers. These result suggests that the shift rotation in the CW direction is more acceptable in terms of the adaptation of hormonal rhythms. These results indicate that the CCW rotation of shift work is somewhat better than CCW rotation for the adaptation to shift work on hormonal aspects in nurses.

Session F : Eukaryotic Gene Structure and Expression : EXPRESSION OF GnRH GENE AND REGULATION OF BREEDING SEASON IN FROGS Ⅲ

Wook Bin Im,Jeong Woo Kim,Dong Gyu Bai 한국생화학분자생물학회 (구 한국생화학회) 1993 추계학술대회집 Vol.- No.-

Assessment of Growth Characteristics and Cell Wall Components in Mutant Cultivars of Kenaf (Hibiscus cannabinus)

Sang Wook Jeong,Jaihyunk Ryu,Seung Bin Im,Soon-Jae Kwon,Joon-Woo Ahn,Jin-Baek Kim,Sang Hoon Kim,Hee-Bong Lee,Si-Yong Kang 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07

This study was carried out to determine the amount of lignin, cellulose, and hemicellulose in six kenaf cultivars during different harvesting stages. Three mutant cultivars (Jangdae, Jeokbong and Baekma), two original cultivars (Jinju, C14), and one Chinese cultivar (Auxu) were planted on May 14, 2013. Four harvesting times were made at intervals of 20 days from 15 July to 16 September, 2013. The overall growth characters of mutant cultivar ‘Jeokbong’ such as plant height, stem diameter, flowering time, and dry mass were similar with those of the original variety. The mutant cultivar ‘Baekma’ occurred 10-day late flowering in comparison with the original variety and also displayed higher dry mass than the original variety. Jinju, Auxu and Jangdae, mid-late maturing kenaf cultivars, had high dry weight compared to early maturing cultivars such as Jeokbong, Baekma and C14. In all cultivars, the lignin contents were increased by a late harvest. The Mid-late maturing kenaf cultivars showed high lignin content in comparison with those of the early maturity cultivars. There were no significant differences of cellulose, and hemicellulose content between the cultivars, however cellulose content in stems of these kenaf cultivars were significantly decreased by a late harvest. These results may provide valuable information to assist the parental selection of kenaf breeding.

TE-TRAP : New Marker System for Gamma Irradiated Sorghum (Sorghum bicolor L.)

Seung Bin Im,Jaihyunk Ryu,Sang-Wook Jeong,Soon-Jae Kwon,Joon-Woo Ahn,Dong Sub Kim,Hee-bong Lee,Si-Yong Kang 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07

The transposable element is a DNA sequence that can be changed its position within the genome, sometimes it can create or reverse mutations and altering the cell's genome size. Target region amplification polymorphism (TRAP) is a rapid and efficient PCR-based marker technique, which uses bioinformatics tools and expressed sequence tag (EST) database information to generate polymorphic markers around targeted candidate gene sequences. TE-TRAP is a new marker system which used terminal inverted repeat (TIR) instead of targeted candidate gene sequences. Sorghum holds a good potential plant organism for transposon tagging due to its small genome size, low amount of repetitive DNA and co-linearity with other cereal genomes, which allows the use of information derived from sorghum in other cereal grasses. IS2868 of sorghum accession was treated Gamma irradiation on seed. To define availability and utilization of TE-TRAP, twenty-one accessions were used to evaluate the genetic diversity and underlying relationships. One-thousand thirty-three TE-TRAP markers were amplified by thirty-one primer combination. Altogether, 712 (62.8%) markers were observed polymorphic segregation, whereas 421 (37.2%) showed monomorphic patterns. To estimate genetic differentiation of population by various gamma radiation doses, the analysis of molecular variance (AMOVA) was performed using 4 to 5 different radiation doses population of M1 sorghum individuals. This study and marker system will provide valuable information to assist radiation mutation breeding.

Chemical Components in the Leaves of Selected Mutant Cultivars of kenaf (Hibiscus cannabinus L.)

Jaihyunk Ryu,Sang-Wook Jeong,Seung Bin Im,Joon-Woo Ahn,Soon-Jae Kwon,Dong Sub Kim,Jin-Baek Kim,Sang Hoon Kim,Si-Yong Kang 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07

Kenaf (Hibiscus cannabinus L.) native to Africa can be used as fiber, food, feedstock and bio plastic. This study was carried out to evaluate the mineral, amino acid and vitamin contents of six selected kenaf cultivars which are enable to produce seed under Korean circumstance. The leaves of three mutant cultivars (Jangdae, Jeokbong and Baekma), two original cultivars (Jinju, C14) and one Chinese cultivar (Auxu) were harvested at flowering time. Mineral components of kenaf leaves, such as calcium, potassium, and mineral, did not showed significant differences among the cultivars. As major amino acids including proline and phenylalanine, significant differences were found in these kenaf cultivars. The Auxu cultivar contained the highest amount of essential amino acid (Phenylalanine, Leucine, Isoleucine, Valine, Methionine and Lysine). The amount of vitamin displayed significant differences such as vitamin E and vitamin K among these cultivars. Especially, Jangdae cultivar contained the highest amount of vitamin E and vitamin K. Thus, these data suggested that Jangdae and Auxu is the most desirable cultivar containing high amount of vitamin and amino acid.

Study on the Salt Tolerance of Rice and Other Crops in Reclaimed Soil Areas : Effects of Varying Plant Spacing and N Levels on Rice Canopy in Reclaimed Salty Area 干拓地에서 水稻生育에 對한 栽植密度와 N 水準變動의 要因效果에 關하여

Im, Hyong Bin,Shim, Jai Wook,Lim, Ung Kyu 서울대학교 1972 서울대학교 論文集 Vol.22 No.-

水稻生育期間中 平均鹽分濃度 7.5㎜hos/㎝, 25℃(0.48%)의 干拓地에서 구사부에를 供試하여 N施肥를 反當 10㎏, 15㎏ 및 20㎏의 3 水準, 3.3㎡ 當栽植株數를 80, 100, 120 및 140의 4 水準의 組合인 12處理를하여 水稻캐노피, 收量要因 및 收量등에 미친 N증비효과와 밀도효과 그리고 그의 相互作用을 보았던바 그 結果를 要約하면 아래와 같다. 1. 幼穗分化期와 出穗期의 個體群 生産構造에 있어서 密植은 그들의 相互遮蔽를 가져오는 同化部의 空間配置로 因하여 個體群 受光能率이 N增肥의 影響에 比하여 크게 低減되는 것으로 보였다. 그뿐만 아니라 密植에 의한 同化部의 增加는 동시에 非同化部의 增加를 크게 가져오나 N 증비효과는 非同化部의 增加를 隨伴치 않았다. 그러므로 C/F 比에 對한 밀도효과는 없으나 N增肥는 그것을 현저히 적게 하였다. 따라서 個體群 同化力/呼吸力比로 보아 N 증비효과는 밀식효과에 비하여 鹽分地에서는 成熟期의 乾物生産을 크게할것이 分明하였으며 LAI에 對한 精租收量은 N증비효과가 밀도효과보다 더컸다. 2. N增肥는 第一伸張節間徑을 比較的 크게하였으나 密植함에 따라 第一伸張節間徑이 작아졌다. 3. 密植과 N增肥에 의한 穗數의 增加는 다같이 顯著하였으며 栽植密度가 높음에 따라 유효경 比率이 크게 떨어 졌으나 N 增肥는 어느 境遇에서도 유효경비율을 현저히 증가시켰다. 穗重에 對한 밀도효과는 현저하였으나 20㎏/10a 에서는 穗重이 크게 떨어졌다. 4. 鹽分地에서는 N增肥는 千粒重과 稔實率을 낮게 하였으나 穗當粒數에는 影響하지 않았다. 密度增加는 千粒重과 稔實率에는 영향하지 않았으나 穗當粒數를 크게 떨어뜨렸다. 5. 以上과 같이 N增肥 효과와 密度의 효과는 生産構造와 收量要因들에 相異한 影響을 미치므로 密度가 N施肥水準은 恒常 2要因을 연관적으로 다루어야 할것으로 생각되었다. 그리고 이와같은 結果로 精租生産에 對한 N增肥曲線은 干拓地에서 15㎏/10a를 變曲點으로 하는 報酬漸減의 現象이 나타났고 또한 N 10㎏/10a를 除外한 두 N 施肥水準에서는 3.3㎡當 100株植을 變曲點으로 最終收量一定의 現象이 나타났다. Field studies were conducted with Kusabue variety and factorial design of 12 treatments composed of 3 levels, 10㎏, 15㎏ and 20㎏ of N per 10a, and 4 levels of 80, 100, 120, and 140 hills per 3.3㎡ plot in reclaimed salty area having an average of 7.5㎜hos/㎝ (25℃), 0.48% salt concentration. The light recieving efficiency of plant canopy was greatly reduced by close planting when compared with the effect of increased N applications in heading stage. The spacing effect on the C/F ratio was not noted but was reduced markedly by the increased N applications, accordingly the spacing effect on rough rice yeilds to the LAI was less than by the increase N application. Closer spacing increased the number of panicle, and non-effective stems, decreased the number of grains per panicle and panicle weight. The increased N applications also increased the number of panicle, reduced the weight of 1,000 grains and the ratio of matured grains. It is recommended to plant 100 hills per 3.3㎡ with the application of 15㎏ N per 10a in the reclaimed salty area of Korea.

Influence of Working Fluids to Heat Transfer Characteristics of Heat Exchanger using Oscillating Capillary Tube Heat Pipe for Low Temperature Waste Heat Recovery

Wook-Hyun Lee,Yong-Bin Im,Ju-Won Kim,Jeung-Hoon Kim,Jong-Soo Kim 대한설비공학회 2001 International Journal Of Air-Conditioning and Refr Vol.9 No.3

Heat transfer characteristics of a heat exchanger for low temperature waste heat recovery using oscillating capillary tube heat pipe(OCHP) were evaluated against the charging ratio variation of working fluid and various working fluids. R-142b, R-22 and R-290 were used as working fluids. The heat exchanger was composed of heat pipe with capillary tube bundles, having a 2.6 ㎜ in outside diameter, 1.4 ㎜ in inside diameter with 101 m length and 140 turns. Charging ratio of working fluid was 40% and 50%. Water was used as secondary fluid. Inlet temperature and mass velocity for each secondary fluid were 297 K, 280 K and 9~27 ㎏/㎡s, respectively. From experimental results, it was found that heat transfer performance of R-22 was higher than those of R-142b and R-290 and it was proportional to Figure of Merit for thermosyphon. As a result, it was thought that R-22 was the most reasonable working fluid of waste heat recovery for low temperature waste heat recovery.

Methylation Pattern of H19 Gene at Various Preimplantation Development Stages of In Vitro Fertilized and Cloned Porcine Embryos

Im, Young-Bin,Han, Dong-Wook,Gupta, Mukesh Kumar,Uhm, Sang-Jun,Heo, Young-Tae,Kim, Jin-Hoi,Park, Chan-Kyu,Lee, Hoon-Taek The Korean Society of Animal Reproduction 2007 Reproductive & developmental biology Vol.31 No.2

Insulin-like growth factor II (IGF2) and H19 genes are mutually imprinted genes which may be responsible for abnormalities in the cloned fetuses and offspring. This study was performed to identify putative differentially methylated regions (DMRs) of porcine H19 locus and to explore its genomic imprinting in in vitro fertilized (IVF) and somatic cell nuclear transferred (SCNT) embryos. Based on mice genomic data, we identified DMRs on H19 and found porcine H19 DMRs that included three CTCF binding sites. Methylation patterns in IVF and SCNT embryos at the 2-, 4-, $8{\sim}16$-cells and blastocyst stages were analyzed by BS (Bisulfite Sequencing)-PCR. The CpGs in CTCF1 was significantly unmethylated in the 2-cell stage IVF embryos. However, the 4- (29.1%) and $8{\sim}16$-cell (68.2%) and blastocyst (48.2%) stages showed higher methylation levels (p<0.01). On the other hand, SCNT embryos were unmethylayted ($0{\sim}2%$) at all stages of development. The CpGs in CTCF2 showed almost unmethylation levels at the 2-,4- and $8{\sim}16$-cell and blastocyst stages of development in both IVF ($0{\sim}14.1%$) and SCNT ($0{\sim}6.4%$) embryos. At all stages of development, CTCF3 was unmethylated in IVF ($0{\sim}17.3%$) and SCNT ($0{\sim}1.2%$) embryos except at the blastocyst stage (54.5%) of IVF embryos. In conclusion, porcine SCNT embryos showed an aberrant methylation pattern comprised to IVF embryos. Therefore, we suggest that the aberrant methylation pattern of H19 loci may be a reason for increased abnormal fetus after embryo transfer of porcine SCNT embryos.

Primary Gastric Small Cell Carcinoma: A Case Identified as a large Subepithelial Tumor from Invisible State in 6 months

Yun Im Lee,Hong Kil Jeon,Jae Wook Im,Sang Yu Oh,Kyung Bin Kim,Byunggyu Kim 대한소화기내시경학회 2019 Clinical Endoscopy Vol.52 No.1

Primary gastric small cell carcinoma (GSCC) is one of the gastroenteropancreatic neuroendocrine tumors. It is a rare cancer with avery aggressive behavior and a poor prognosis because of the high rate of metastases. It is usually found in far advanced stage. Weexperienced a case of GSCC which had developed into a large subepithelial tumor (SET) from invisible state in a short period. A65-year-old man consulted our hospital because of early gastric cancer. He underwent endoscopic submucosal dissection for the earlygastric cancer at high body posterior wall. After 6 months, the follow-up endoscopy showed a large newly developed SET-like lesionwith central ulceration at the gastric cardia. Endoscopic biopsy revealed GSCC. Total gastrectomy was performed. One out of the 26perigastric lymph nodes had a metastasis. He received 6 cycles of adjuvant chemotherapy with etoposide and cisplatin. He is still ingood health 12 months after operation.