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      • KCI등재

        Correlation Between food Processing-Associated Stress Tolerance and Antimicrobial Resistance in Food Pathogens

        Woode, Benjamin Kojo,Daliri, Frank,Daliri, Eric Banan-Mwine The Korean Society of Food Hygiene and Safety 2020 한국식품위생안전성학회지 Vol.35 No.2

        최근 최소한으로 가공된 안전한 식품에 대한 소비자의 수요가 기하급수적으로 증가하고 있다. 이러한 이유로 많은 식품가공 업체에서는 식품안전을 강화하고 유통기한을 연장하기 위한 최소한의 가공공정 중 허들기술(hurdle technology)을 적용하고 있다. 한편, 연구에 따르면 식품에 함유된 병원균을 비활성화하기 위한 공정 및 방법들은 식중독세균들의 스트레스 적응 메커니즘을 촉발시켜 심지어 후속 치료로 부터 교차 보호를 준다. 또한, 항생제와 제초제 사용과 같은 일상적인 농장 관행은 항생제 내성을 가진 병원균의 생성을 초래할 수 있다. 이러한 항생제 내성 박테리아는 식품 처리과정과 관련된 스트레스에 내성을 가질 수 있고 가공 식품에서 생존할 수 있는 가능성을 높일 수 있다. 이 리뷰에서는 식품가공과 관련된 스트레스와 항생제 내성의 상관관계에 대해 논의한다. 또한, 항균성 화합물 및 기타 식품 처리 관련 스트레스에 대한 교차 보호 수단으로서 시그마 인자(sigma factors), SOS 반응 경로(SOS response pathways) 및 유출 펌프(efflux pumps)의 사용과 같은 분자유전학적 기작에 대해서도 논의한다. Recently, consumer demand for safe but minimally processed food has rapidly increased. For this reason, many food processing industries are applying hurdle technology to enhance food safety, extend shelf life, and make foods appear minimally processed. Meanwhile, studies have shown that a treatment (stress) meant to inactivate foodborne pathogens may trigger adaptation mechanisms and could even offer cross protection against subsequent treatments. Also, certain routine farm practices such as antibiotic and herbicide use could result in the development of antibiotic-resistant pathogens. Such bacteria may be tolerant to food processing-associated stress and be more likely to remain viable in processed foods. In this review, we discuss the correlation between food processing-associated stress and antibiotic resistance. We also discuss molecular mechanisms such as the use of sigma factors, SOS response pathways and efflux pumps as means of cross protection against antimicrobial compounds and other food processing-associated stresses.

      • KCI등재

        Correlation Between food Processing-Associated Stress Tolerance and Antimicrobial Resistance in Food Pathogens

        Benjamin Kojo Woode,Frank Daliri,Eric Banan-Mwine Daliri 한국식품위생안전성학회 2020 한국식품위생안전성학회지 Vol.35 No.2

        최근 최소한으로 가공된 안전한 식품에 대한 소비자의 수요가 기하급수적으로 증가하고 있다. 이러한 이유로 많은 식품가공 업체에서는 식품안전을 강화하고 유통기한을 연장하기 위한 최소한의 가공공정 중 허들기술(hurdle technology)을 적용하고 있다. 한편, 연구에 따르면 식품에 함유된 병원균을 비활성화하기 위한 공정 및 방법들은 식중독세균들의 스트레스 적응 메커니즘을 촉발시켜 심지어 후속 치료로부터 교차 보호를 준다. 또한, 항생 제와 제초제 사용과 같은 일상적인 농장 관행은 항생제 내성을 가진 병원균의 생성을 초래할 수 있다. 이러한 항생제 내성 박테리아는 식품 처리과정과 관련된 스트레스에 내성을 가질 수 있고 가공 식품에서 생존 할 수 있는 가능성을 높일 수 있다. 이 리뷰에서는 식품 가공과 관련된 스트레스와 항생제 내성의 상관관계에 대해 논의한다. 또한, 항균성 화합물 및 기타 식품 처리 관련 스트레스에 대한 교차 보호 수단으로서 시그마 인자 (sigma factors), SOS 반응 경로(SOS response pathways) 및 유출 펌프(efflux pumps)의 사용과 같은 분자유전학적 기작에 대해서도 논의한다. Recently, consumer demand for safe but minimally processed food has rapidly increased. For this reason, many food processing industries are applying hurdle technology to enhance food safety, extend shelf life, and make foods appear minimally processed. Meanwhile, studies have shown that a treatment (stress) meant to inactivate foodborne pathogens may trigger adaptation mechanisms and could even offer cross protection against subsequent treatments. Also, certain routine farm practices such as antibiotic and herbicide use could result in the development of antibiotic-resistant pathogens. Such bacteria may be tolerant to food processing-associated stress and be more likely to remain viable in processed foods. In this review, we discuss the correlation between food processing-associated stress and antibiotic resistance. We also discuss molecular mechanisms such as the use of sigma factors, SOS response pathways and efflux pumps as means of cross protection against antimicrobial compounds and other food processingassociated stresses.

      • SCOPUSKCI등재

        LIVING PLANTS TO IMPROVE INDOORAIR QUALITY

        R.A. Wood,M.D.Burchett,R.L.Orwell 韓國植物 ㆍ人間 ㆍ環境學會 1998 인간식물환경학회지 Vol.1 No.1

        몇몇 널리 퍼져있는 대기오염 물질들이 많은 사람들에게 심각한 건강문제를 계속해서 초래하고 있다. 사실 거의 모든 사람들이 위험에 노출되어 있다고 해도 과언이 아니다. 외부공기에서 발견되고있는 대부분의 오염물질들이 실내공기에서도 발견되있으나 외부공기보다 실내에서 더 집중되어 있다. 따라서 실내공기의 호흡이 인간의 많은 오염물질에 대한 조출에의 주된 결정요소라는 것이 인정되었다. (Krzyzanowski. 1995). 식물들이 그들의 일반적인 생리작용에 의해 많은 잠재적인 유독성의 환경화학물질들은 대사시킬수 있을 거라는 증거들이 증가하고 있다. (Sanderman. 1992, Dennis et at. 1997) 켄차야자를 실내식물구조의 모델로한 지금까지의 연구는 (Burchett et al. 1997, Wood et al. 1997) 식물이 실내공기속의 소실되기 쉬운 기관적 오염물질의 최대 노출 수준을 수차례 제거하는 능력을 가지고 있다는 사실을 보여주고 있다. Some widespread air pollutants continue to pose serious public health risks for many poeple, in fact nearly everyone is at risk. Many pollutants found in outdoor air are found in indoor air but at a higher concentration than outdoors, consequently it is acknowledged that inhalation of indoor airis the major determinant of human exposure to many pollutants (Krzyzanowski, 1995), There is increasing evidence that plants may be able to metabolize many potentially toxic environmental chemicals as part of their normal physiology (Sanderman 1992:Dennis et at, 1997). Work to date (Burchett et at, 1997, Wood et al, 1997), has shown that Kentia palm as a model for indoor plant system, has the capacity to remove several times the maximum occupational exposure levels of volatile organic compounds (VOCs) in indoor air.

      • SCIESCOPUS

        Wind loads on industrial solar panel arrays and supporting roof structure

        Wood, Graeme S.,Denoon, Roy O.,Kwok, Kenny C.S. Techno-Press 2001 Wind and Structures, An International Journal (WAS Vol.4 No.6

        Wind tunnel pressure tests were conducted on a 1:100 scale model of a large industrial building with solar panels mounted parallel to the flat roof. The model form was chosen to have the same aspect ratio as the Texas Tech University test building. Pressures were simultaneously measured on the roof, and on the topside and underside of the solar panel, the latter two combining to produce a nett panel pressure. For the configurations tested, varying both the lateral spacing between the panels and the height of the panels above the roof surface had little influence on the measured pressures, except at the leading edge. The orientation of the panels with respect to the wind flow and the proximity of the panels to the leading edge had a greater effect on the measured pressure distributions. The pressure coefficients are compared against the results for the roof with no panels attached. The model results with no panels attached agreed well with full-scale results from the Texas Tech test building.

      • Dense Downtown vs. Suburban Dispersed: A Pilot Study on Urban Sustainability

        Wood, Antony,Du, Peng Council on Tall Building and Urban Habitat Korea 2017 International journal of high-rise buildings Vol.6 No.2

        This paper presents the initial findings of a ground-breaking two-year CTBUH-funded research project investigating the real environmental and social sustainability of people's lifestyles in a number of high-rise residential towers in downtown Chicago, and a comparable number of low rise homes in suburban Oak Park, Chicago - based on actual energy bills and other real data. The study is ground-breaking because, to date, similar studies have been mostly based on very large data sets of generalized data regarding whole-city energy consumption, or large-scale transport patterns, which often misses important nuances. This study has thus prioritized quality of real data (based on around 250 households in both high rise and low rise case studies), over quantity. In both urban and suburban cases, the following factors have been assessed: (i) home operational energy use, (ii) embodied energy of the dwelling, (iii) home water consumption, (iv) mobility and transport movements, (v) urban/suburban Infrastructure, and (vi) quality of life. The full results of this seminal study will be published in the form of a CTBUH Research Report publication in 2017. Presented below is an overview of the initial (and, currently, unverified) findings of the research, together with the limitations of the study that should be taken into account, as well as future plans for developing this important pilot study.

      • Systematic control of heteroatoms in donor-acceptor copolymers and its effects on molecular conformation and photovoltaic performance

        Wood, Sebastian,Kim, Ji-Hoon,Wade, Jessica,Park, Jong Baek,Hwang, Do-Hoon,Kim, Ji-Seon The Royal Society of Chemistry 2016 Journal of materials chemistry. C, Materials for o Vol.4 No.34

        <P>Heteroatom substitutions are an effective means of tuning the optoelectronic, conformational, and molecular packing properties of donor-acceptor conjugated copolymers, with a view to efficient photovoltaic performance. We investigate the effects of systematic sulfur/selenium substitutions into thiophene (donor) and benzothiadiazole (acceptor) units using complementary Raman spectroscopy, density functional theory, and X-ray diffraction to characterise the resulting copolymers. We find that, in each case, the heavy atom substitution is detrimental to photovoltaic performance and undertake to understand this in terms of fundamental optoelectronic properties of the copolymers. Specifically, we find that, due to mesomeric effects, the selenium atom donates electron density into the donor unit (selenophene) more strongly than sulfur, but also withdraws electron density more strongly from the benzene ring in the acceptor unit (benzoselenadiazole). In both cases, the selenium substitution reduces the optical energy gap but is unfavourable for intermolecular packing in thin films and so results in poor charge carrier mobility. We identify a complex interplay between the electronic properties of the substituted donor and acceptor units relating to the frontier molecular orbital energy levels, molecular conformation, and intermolecular packing of the copolymers. In particular, we find that the pairing of a strong acceptor unit with a weak donor unit results in relatively low electron density on the conjugated backbone, leading to high inter-unit torsion and weak optical absorption in the visible range. The methods and insights developed here have broad applicability to the design of other donor-acceptor copolymers for optoelectronic device applications.</P>

      • SCISCIESCOPUS

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