李東垣의 生涯와 醫學思想

崔三燮,洪元植 慶熙大學校韓醫科大學韓醫學硏究所 1981 慶熙韓醫大論文集 Vol.4 No.-

혈액투석환자 배우자의 스트레스와 대응에 관한 연구

원삼순,권혜진 중앙대학교 의과대학 의과학연구소 1992 中央醫大誌 Vol.17 No.4

This descriptive study designed to identify stress factors and level and helpful coping methods of hemodialysis patient's spouse. Data were collected from 60 subjects who were spouses of hemodialysis patient of conveniently selected 4 Hemodialysis Units in the city of Seoul. The Collection of data it was carried out by the researcher from the 7th of Octobor to 20th of October, 1992. Two instruments were used to collect the data ; 1. Stress questionaire was developed by researcher which was combined review of literature and the result of interviewer, consisted 30 stress factor items and measured by five point Likert scale. The items were categorized physical, psychological and socioeconomic area. 2. Helpful coping questionaire developed by investigator through literature review and result of interviewer, included 50 items and measured by five point Likert scale. Helpful coping items were classified into two categories, the problem oriented and the affective oriented. Data was analyzed by S.A.S. computer porgram using percentile, means and standard deviation, t-test and Pearson correlation coefficient. The results of this study are summerized as follows 1. The spouses of hemodialysis patient were found to be stressful in general and the items with high stress were "To be treated indefinite period of time", "Uneasiness of trevel", "To be say with their spouse who suffer pain", "To ingest medication continuously", "Financial burden", "No treatment except kidney transplantation", "Anxious about disease transmission due to transfusion" and the highest stress category was physical. 2. The spouses of hemodialysis patient were shown to be helpful by the coping methods and the most helpful coping items "To accept as a fate" and "Self condolence comparing others who were in a more serious rather than thier sitution" and the higher helpful coping method was affective oriented. 3. The result of the analysis of the relationship between scores of stress categories and general characteristics was as follows : Spouse's sex, house shape, and occupational status before the patient got illness showed a statistically significant difference in score of stress categories(P<0.05) 4. The result of the analysis of the relationship of the relationship between helpful coping methods and general characteristics was as follows : The number of family, the state of medical insurrance, spouse's disease, the number of hemodialysis, and having or not having complication related with hemodialysis showed a statistically significant differance in helpful coping methods(P<0.05) 5. There was significant differance among stress categories and coping methods.(P<0.01)

디스크 배열

元裕憲,金鍾勳,盧三赫 弘益大學校 科學技術硏究所 1995 科學技術硏究論文集 Vol.6 No.-

Disk arrays were proposed in the 1980`s as a way to allow parallelism between multiple disks to improve aggregate I/O performance. Today they appear in the product lines of most major computer manufactures. This paper gives a comprehensive overview of disk arrays and provides a framework in which to organize current and future work. First, this paper introduces disk arrays in general, and reviews the driving forces that have popularized disk arrays : performance and reliability. It discusses the two architectural techniques used in disk arrays, striping across multiple disks to improve performance and redundancy to improve reliability. Next, this paper describes 6 disk array architectures, namely RAID levels 0∼5. It goes on to discuss advanced research and implementation topics such as the way in which parity is distributed in a RAID, and the means of refining the basis RAID levels to improve performance. Finally, this paper describes software disk arrays which allow writing data redundantly across an array of disks in workstations distributed across the network.

貿易關係法의 새로운 定立方向

李廛三,文哲漢,吳元奭,朴南圭 청주대학교 기업경영학연구소 1986 經營學論集 Vol.8 No.-

수 종의 상피기원 종양 세포주에서 방사선 조사와 표피성장인자 투여에 따른 세포 주기의 변화와 apoptosis 유발에 관한 연구

한원정,허민석,이삼선,최순철,박태원 대한구강악안면방사선학회 2000 Imaging Science in Dentistry Vol.30 No.1

Purpose : This study was aimed to evaluate the cell cycle arrest and apoptosis induction after irradiation and epidermal growth factor(EGF) treatment in three human epithelial tumor cell lines (A43l, Siha, KB). Materials and Methods : Single irradiation of 2, 5 and 10 Gy was done on three cell lines with 5.38 Gy/min dose rate using Cs-137 irradiator at room temperature. Also, EGF of 10 ng/ml was added immediately after 10 Gy irradiation. Cell growth was evaluated by counting the living cell number using a hemocytometer at 1 day, 2 days, 3 days, 4 days and 5 days after irradiation. Cell cycle arrest and apoptosis induction were assayed with the flow cytometry at 8 hours, 12 hours, 1 day, 2 days, 3 days, 4 days and 5 days after irradiation. Results : Growth of irradiated three cell lines were inhibited in proportion to radiation dose, EGF treatment after irradiation showed various results according to cell lines. On all cell lines, G2 arrest was detected after 8 hours and maximized after 12 hours or 1 day. Amount of G2 arrest was positively dose dependent. However, EGF showed no significant change on G2 arrest. G2 arrest was recovered with time at 2 Gy and 5 Gy irradiation. However, at 10 Gy irradiation, G2 arrest was continued. Apoptosis was detected at 10 Gy irradiation. On EGF treated group after irradiation, A431 and Siha cell lines showed slightly increased apoptosis but there was no statistically significant difference. KB cell line showed no marked change of apoptosis induction. Conclusion : Irradiation effects on cell cycle arrest and apoptosis induction in three human epithelial tumor cell lines, however epidermal growth factor doesn't effect on. (Korean J Oral Maxillofac Radiol 2000; 30: 71-79)

北韓統治 이데올로기 硏究

姜三元 啓明大學校 社會科學硏究所 1989 한국사회과학연구 Vol.8 No.-

치수 및 치근단병소에서 Prostaglandin E₂, 6-keto-prostaglandin F₁α, Leukotriene B₄의 분포에 관한 연구

임성삼,백승호,손원준 大韓齒科保存學會 2000 Restorative Dentistry & Endodontics Vol.25 No.2

도덕과 열린수업

이경원,정삼현 晋州敎育大學校 初等敎育硏究所 1997 初等敎育硏究 Vol.7 No.-

Interleukin-2가 Mouse간의 인산염분해효소의 활성에 미치는 영향

이규식,김원규,정호삼,강성섭 한양대학교 의과대학 1989 한양의대 학술지 Vol.9 No.1

In recent years, interleukin-2, a lymphokine produced by antigen or mitogenstimulated lymphocytes, has been intensively with the development of immunooncology and chemoimmunotherapy of the malignant tumor. Interleukin-2 mediates antitumor effect by stimulating the proliferation of helperand cytotoxic T cells, augmenting the cytolytic activities of cytotoxic T-lymphocytes and differentiating T-lymphocytes into a lymphokine-activated killer cell in vivo. Thus interleukin-2 induces the therapeutic effects on various sarcoma and carcinoma and regresses the pulmonary, hepatic and peritoneal metastases of various tumors. Although interleukin-2 is very effective for the treatment of various malignancy, it develops many side effects including fever, chill, malaise, mental confusion, diarrhea, vomiting and oliguria and causes pulmonary, hepatic and renal toxicities. Especially interleukin-2 results in increase of capillary permeability with weight gain, pulmonary edema, and ascites. In this experiment, the author studied the effect of interleukin-2 on the mouse liver, histochemically observing the changes in the activities of alkaline phosphatase, acid phosphatase and adenosine triphosphatase. Male mice, DDY strain, weighing 20gm, were used as experimental animals. The experimental animals were sacrificed at 3, 6, 12, 24 and 48 hours after intraperitoneal administration of two milions unit of interleukin-2 per kilogram of body weight. The specimens obtained from the liver were fixed in 10% neutral buffered formalin solution for 24 hours at 4℃ and sliced at 16㎛ thickness in a frozen cryostat. The activities of alkaline phosphatase and acid phosphatase were observed by the Gomori's method and the activity of adenosine triphosphatase was observed by the Wachstein and Meisel's method for histochemical study. The results obtained were as follows. 1. The acid phosphatase activity was strong positive at 12 hours and 24 hours groups in the central and portal zones of the liver lobules, but weak positive and moderate positive at 48 hours group in the central and portal zones of the liver lobules, respectively. 2. The alkaline phosphatase activity was weak positive at 6 hours and 12 hours groups and moderate positive at 48 hours group in the central and portal zone of the liver lobules. 3. The adenosine triphosphatase activity was trace positive in the central zone and weak positive in the portal zone of the liver lobules at 6 hours group but moderate positive at 48 hours group in the central and portal zones of the liver lobules. Consequently, it is suggested that interleukin-2 induce degenerative changes of the hepatocytes of the mouse, but it is recovered with time.

평생교육 참여결정이론에 관한 연구

곽삼근,이숙원 이화여자대학교 사범대학 교육과학연구소 2003 교육과학연구 Vol.34 No.3

평생교육에서 학습자의 참여결정과정은 평생에 걸쳐 지속적으로 다양한 요인들이 복합적으로 상호작용하는 과정으로 이해할 수 있으므로, 평생교육 참여에 관한 논의도 장기적이고 종합적 접근이 요구된다. 즉, 초기의 참여결정에서 계속적인 참여과정에 이르기까지의 장기적인 과정에 영향을 미치는 개인적, 심리적, 사회적, 교육기관 및 제도적, 환경적 특성들의 영향력을 종합적으로 규명하는 시도가 필요하다. 따라서 이 연구는 우선 장기적이고 종합적인 평생교육 참여결정 모형 개발을 위한 준거 틀을 제공하는 데 목적을 두고, 초기 참여결정과 참여지속결정에 관한 선행연구들을 분석적으로 고찰한 후 이를 토대로 다차원적 참여결정 관련요인들을 종합˙정리하였다. 연구결과, 초기 참여결정과 참여지속결정 모두에 관련된 요인들로 학습자의 배경 특성, 학습자의 사회경제적 특성, 학습자의 심리적 특성, 학습자의 학습환경 특성, 교육기관의 특성, 프로그램의 특성, 교육기관의 환경 특성, 제도적/사회적 환경 특성 등을 제시하였으며, 참여지속 혹은 중도탈락결정에는 교육경험 특성이 추가적인 요인으로 나타났다. 그러나 개인관련 특성도 상당 부분 학습자의 외부 여건이나 제도의 개선, 교육기관의 노력으로 해결할 수 있음을 알 수 있다. 따라서 이 연구에서는 결론으로서 평생교육 기회 확대 및 활성화를 위한 교육기관 차원과 사회제도적 차원의 과제로서, 평생교육기관의 공동체화, 개인적˙사회적 목적의 통합 및 조화, 평생교육지원제도 구축 및 환경 조성 등을 제안하였다. In lifelong education, learners are affected by various factors in making a decision of participation in their life time. The study on participation in lifelong education thus requires the inclusive and the long-term approach. This study attempts to elucidate the various factors that derive from individual, Psychological, social, institutional and environmental aspects, It should also cover the beginning stage where learners make a decision of participation for the first time as well as the continuing stage where learners make a decision about persistence of their education. Accordingly, this study aims to provide a framework to develop a long-term and inclusive participation model of lifelong education. The previous studies on participation theory(Miller, Rubenson, Darkenwald & Merriam, Cookson, and Henry & Basile) and persistence/dropout model(Boshier, Mackinnon-Slaney, Thompson, Tinto, and Bean & Metzner) are analyzed and the related factors in the diverse aspects are summarized. The results of the study show that the related factors of participation and persistence are found in learners, institutions, and policies; learners' personal information, socio-economic status, Psychological characteristics, learning environments, educational institutions, Programs, institutional environment, and social system and policies, In addition, educational experience in institutions is another important factor for persistence or dropout. Also, the non-participation and dropout of learners can be resolved by improvement of learning environment, Policy change, and institutional support. It is thus concluded that community of lifelong education, integration and harmony of individual and social purposes, support system of lifelong education, and the better educational environment should be established for providing and expanding chances of lifelong education.