Junctional Rhythm을 보인 한국형 출혈열 1례

이성원,이수훈,최대현,손영기,차광수,손춘희,정원태,김성은,김종성 동아대학교의과대학 1997 동아의대학술지 Vol.9 No.1

THIN FILMS BEHAVIORS OF POLY(4-METHYL PHENYL METHACRYLATES) AT THE AIR-WATER INTERFACE

김동원,홍준표,박상래 공주대학교 기초과학연구소 1992 論文集 Vol.30 No.1

Langmuir-Blodgett monolayer and multilayers of poly(4-(methyl) phenyl methacrylates), PMPMA, were investigated. The surface pressure-area isotherms are dependent on various conditions; temperature, molecular weight, subphase pH and compressing speed. Transfer ratios of PMPMA on various substrates, Si wafer, glass, quartz plate at different surface pressures were measured with horizontal and vertical dipping method. The multilayer LB alms deposited on substrates are characterized by UV and ellipsometry.

結核病棟 入院患者 喀痰에서 分離한 Nocardia屬의 同定과 藥齋 減受性에 關한 實驗

高春明,金駿杰,李正碩,李一善,李沅泳 최신의학사 1974 最新醫學 Vol.17 No.9

This study was. carried out for the identification and drug susceptibility of Nocardia species iso?lated from the sputum of pulmonary tuberculosis patients at Severance Hospital from May, 1973 to May, 1974. The results as follows: 1. Among the 138 experimental specimens, eleven of the Nocardia species were identified by the methods of direct microscopic observation and culture characteristics. 2. Of the eleven Nocardia species, 6 of the Nocardia species were identified N. asteroides, 3 of the N. brasiliensis and 2 of the strains could not identified with a ordinary methods. 3. Antimicrobial activity of experimental strains to the several antibiotics, Ampicillin, Oxacilin and Cloxacillin were excellent against to the tested groups and Streptomycin, Chloramphenical and Gantrisin were also moderated effective to the experimental group.

골수이식 후 골밀도 및 골대사의 변화 : 2년 추적관찰 2-Year Prospective Study

이원영,강무일,오은숙,오기원,한제호,손현식,윤건호,차봉연,이광우,손호영,강성구,신완식,민우성,김춘추 대한내분비학회 2000 Endocrinology and metabolism Vol.15 No.4·5

동종골수이식 후 혈당 및 혈중 지질농도의 변화양상 및 관련인자

이원영,강무일,오은숙,오기원,손현식,윤건호,차봉연,이광우,손호영,강성구,신완식,민우성,김춘주 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.24 No.6

연구배경:골수이식은 비교적 젊은 연령의 환자들을 대상으로 하며 면역억제제의 사용기간이 비교적 짧으므로, 주로 고령의 만성 질환 환자에서 시행되는 고형장기이식에서와는 달리 당대사 및 지단백 대사에 있어서 많은 차이점이 있을 것으로 추측된다. 저자들은 전향적 연구를 통하여 골수이식 후 시기별로 혈당 및 혈중지단백 변화 양상을 알아보고 이와 관련된 임상인자들을 규명하고자 하였다. 방법:1998년 10월부터 1999년 8월까지 가톨릭대학교 성모병원에서 동종골수이식을 시행한 환자들 중 43명을 대상으로 이식 전 및 이식 후 1, 2, 3, 4주와 3개월, 6개월에 공복 혈당, 혈중 총 콜레스테롤, 중성지방, 고밀도지단백을 측정하여 골수이식 후 시기별 변화를 관찰하고 여러 임상인자들에 따른 차이를 알아보았다. 결과:1. 공복혈당은 골수이식 수 첫4주 동안 상승하였고 이후 감소하였으나 이식 6개월 시점의 평균 공복혈당은 이식 전보다 유의하게 높게 관찰되었다. 혈중 총 콜레스테롤은 이식 후 1주에 최고치를 형성하였고 이후 기저수준으로 회복되었다가 이식 수 3,6개월에 다시 증가하여 기저치에 비해 유의하게 높았다. 혈중 중성지방은 이식 후 1개월까지 유의하게 증가하였고 이후 감소하여, 3,6개월에는 기저치와 유의한 차이가 관찰되지 않았다. 혈중 고밀도지단백은 이식 후 2,3주에 이식 전보다 유의하게 감소하였고 이후 이식 전 수준으로 회복되었다. 혈중 저밀도지단백은 총 콜레스테롤의 변화와 매우 유사하였다. 2. 골수이식 후 6개월 시점에서 공복 혈당이 126㎎/dL이상인 환자는 7명(16%)이었다. 이들 환자들과 공복혈당 126㎎/dL 미만의 환자 36명을 비교한 결과, 공복혈당이 126㎎/dL 이상인 환자군에서 스테로이드 평균 투여량이 많았고 고밀도지단백이 유의하게 낮았다. 3. 이식편대숙주질환이 발생한 환자는 그렇지 않은 환자보다 이식 후 1, 2, 3주 및 6개월의 총 콜레스테롤이 더 낮았고, 3개월의 공복혈당이 더 높았다. 혈연골수이식 환자군은 비혈연골수이식 환자에 비해 투여된 스테로이드 용량이 더 적음에도 불구하고 이식 후 1, 2, 3주 및 6개월의 총 콜레스테롤 수치가 더 높았다. 스테로이드 고용량 투여군(하루 평균 7.5㎎기준)은 저용량군보다 이식 후 3개월 시점의 공복혈당이 더 높았으나 나머지 시점의 혈당, 혈중 지질농도에 있어서는 유의한 차이가 관찰되지 않았다. 결론:골수이식 후 초기시기에 주로 당 대사 및 지질대사이상이 관찰되며 이는 면역억제제 투여와 관련이 있음을 알 수 있었다. 면역억제제가 고용량 투여되는 합병증 발생 시 이들 대사이상에 관심을 기울여 대처해야 할 것이다. Background: In bone marrow transplantation(BMT), recipients are usually younger and immunosuppressants are open used in shorter period than in solid organ transplantation. Therefore, there might be a difference in glucose and lipid metabolism between BMT and solid organ transplantation. However, the serial changes of metabolic parameters following BMT have not been studied. Therefore, the aim of this study is to investigate the serial changes of blood glucose, lipids and the putative factors that are related with these changes after BMT. Methods: We have prospectively investigated 43 patients who underwent allogeneic BMT. Fasting plasma glucose(FPG), total cholesterol, triglyceride and high-density lipoprotein(HDL) were measured before BMT, and at 1, 2, 3, 4, 12 weeks and 6 months after BMT. The serial changes of these metabolic parameters according to clinical factors including type of BMT, mean daily steroid dosage, and occurrence of graft versus host disease (GVHD) were examined. Results: 1. Mean FPG level increased during 4 weeks after BMT and remained above basal value at post-transplant 6 months. Total Cholesterol level was increased during initial 4 weeks after BMT and was above basal value at post-BMT of 3 and 6 months. Triglyceride level was progressively increased during initial 4 weeks after BMT, but returned to basal value there after. HDL-cholesterol level was significantly decreased during initial 4 weeks after BMT, but returned to basal value there after. 2. Patients with FPG above 126 mg/dL and the other patients, the former received larger amounts of daily steroid and had lower HDL-cholesterol level. 3. The changes of metabolic parameters were different according to type of BMT, steroid dose, and occurrence of GVHD. Conclusion: Although there was increase of FPG, TC, TG and decrease of HDL-C during initial 4 weeks after BMT, these metabolic changes recovered slowly thereafter. Immunosuppressants are thought to be associated with these changes. Further observation will be needed for the long-term effect of BMT on metabolic changes(J Kor Diabetes Asso 24:689~698, 2000).

ICT를 활용한 구성주의적 수업이 과학개념 획득과 문제해결에 미치는 효과

이춘희,정원우,김중욱,이윤종 慶北大學校 科學敎育硏究所 2004 科學敎育硏究誌 Vol.28 No.-

The purpose of this study is to examine in details the effects of the constructive instruction on the acquisition of scientific conceptions and the problem solving of Science based on ICT (Information and Communication Technology). In this study, An examination tool developed for a previous learning concept was applied to instructional model by a constructivism to students, and by grasping a previous learning concept and using ICT. An way of the improvement about acquisition of scientific conceptions and problem solving of subject was inspected, the rate of a correct answer, the decrease rate of misconception, and the achievement rate of a periodical examination were compared. The result of such enforcement was as follows; The motivational induction for learning, the interesting rate, and the rate of a correct answer in an experimental group showed highly. The result of a examination between an experimental group and a comparative group showed similarly. The rate of accomplishment also showed highly in an experimental group. Accordingly, the constructive instruction using ICT proved to be fit for seventh educational course as a student-centered course. The change of recompositional course for knowledge from a previous learning concept to a new one showed clearly.

Rousseau의 體育思想에 關한 考察

閔春基,元周潤,李政欣 忠南大學校體育科學硏究所 1987 體育科學硏究誌 Vol.5 No.1

His thought of physical Education is following. The 1st, He said that physical training inflected by nature helps the health of sprit. The 2nd, He said that we must always train the organization of sensitive part and judgement ability should be harmonized. The 3rd, He said that it is good for us to give out the curiosity to other sex through phyeical training. The 4th, As the positive physical training, entertaining life one’s hobby and endurance reduces the symptous of senility. He said, the physical Education through all his life is requested. The 5th, He said, in order to achieve the nature of femal and to do her duty, woman’s physical Education is requested. He said in order to do one’s comfortable home life and social life adultry physical Education is requested. J.J.Rousseau’s educational theory was developed in the direction of educational renovation as well as social reform, so it become the prime mover of the French Revolution. His thought of physical Education was reformative enough to influence many education alist, and there were its followers called the philanthropists. J.J.Rousseau’s thought of physical Education, which appeared to stress naturalism and training in patience was handed down to Basedow who was influenced by it after reading Emile. The thought helped to start the modern school’s physical Education by being adopted as a curriculum of the philanthropic school. It was handed down to Salzmann and Guts Muths who made its further development, and it led the modern physical Education. We must recognize the efforts that he contribute to our physical Education as the effect of education whatever our oppionian is about Rousseau’s merits as a thinker.

완전뇌허혈후 재관류시에 국소뇌혈류, 체성감각유발전위 및 신경학적 회복에 대한 Mannitol과 Thiopental의 효과

박춘근,이상원,박영섭,최승진,허필우,정동섭,강준기,최창락 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.2

The cardiopulmonary bypass or cerebral circulation arrest is often used in the treatment of complex aneurysm or of arteriovenous malformation to decrease the risk of intraoperative aneurysm rupture. Although experimental studies have suggested that some drugs may protect the brain from ischemic injury, there are limitations in maintaining cerebral perfusion arrest without incurring neurologic deficits due to the initiation of detrimental processes including excitotoxic neuronal injury, activation of phospholipases, influx of calcium, and generation of damaging free radicals. The purpose of this study is to determine wheter mannitol or thiopental has any favorable effects on the recovery of neurologic deficits and on the regional cerebral blood flow(rCBF), somatosensory evoked potential(SEP) and electroencephalogram(EEG) in cats which underwent 15 minutes-complete global ishcemia-reperfusion. The complete global ischemia was produced in 38 cats by temporary intrathoracic occlusion of the innominate artery and the subclavian artery following ligation of bilateral mammary arteries and simultaneous induction of hypotension. The cats were allocated randomly to one of 4 treatment groups : (1) control group, 8 cats received equal volume of saline solution : (2) thiopental group, 10 cats received 45㎎/㎏ thiopental intravenously, (3) mannitol group, 10 cats received 2g/㎏ mannitol intravenously, (4) combined mannitol and thiopental group, 10 cats received equal dose of mannitol and thiopental intravenously. The drugs were administrated in a equally divided dosage before and after the ischemic episode. The results were as follos : 1) Eight animals which received saline showed the severe postischemic hypoperfusion and poor recovery of SEP and EEG, and 6 of them died within 6 hours after the ischemia. 2) Ten thiopental-treated animals also showed the severe postischemic hypoperfusion and poor recovery of SEP and EEG, and 6 of them died within 6 hours the ischemia. 3) Both mannitol-and combined treated groups showed early recovery of EEG, good recovery of SEP and EEG without the severe postischemic hypoperfusion, and 7 of 10 mannitol-treated animals and 8 of 10 combined treated animals were significantly recovered in all parameters. There were not significant differences in all parameters between the mannitol-and combined treated groups. 4) Thirty-four of 38 animals involved in this 15 minutes-ischemia resulted in the severe neurologic deficits inspite of treatment with mannitol, thiopental or both of them. These results suggest that, in cats, mannitol treatment is effective but not thiopental in preventing severe neurologic injury following complete global ischemia and the duration of complete ischemia should be far less than 15 minutes.

鋼管多段 Grouting 工法의 Tunnel 補强效果에 關한 硏究

박진원,류체천,김송만,박춘수 충남대학교 산업기술연구소 2001 산업기술연구논문집 Vol.16 No.1

When Umbrella Arch Method is applied in construction of the first Ok-chon tunnel which have soft ground zone or fractured zone, the result as finite element analysis method, the PENTAGON-2D, is following. 1)There is little effect in bottom displacement due to side wall reinforcement, but side wall displacement decrease 50%. 2)Before reinforced by Umbrella Arch Method, rockbolt axial stress is 16 ton which exceed allowed axial stress, however after reinforced, that is about 5.5ton in up and down path, therefore rockbolt axial stress after reinforced is safe. 3)In shotcrete, compression stress decrease average 65% and shearing force and bending moment is decrease more than average 65%. hence shotcrete has great effect on ground reinforcement in side wall. 4)Umbrella Arch Method was proven as assistant method in fractured zone, but in long term stability, judging the fact that bottom displacement is slightly great, the tunnel invert is continued. Or bottom must be reinforced with reinforced with reference to field measurement data in excavation.

특성화학교에 따른 소년보호시설의 건축계획에 관한 연구

이기원,윤춘섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(계획계)

The purpose of this study is to suggest how juvenile training schools should be planned and designed. Juvenile training schools house young people of over 12 to 20 years who are on the probation of Juvenile Department. The schools are established to give new life to young people who have once committed crime by teaching and training for a limited time. These institutions help such young people to avoid the vicious circle of potential crimes. Nowadays Juvenile training schools are renamed to Specialization schools. Nevertheless, the physical environment which house the young people remains unchanged. This study intends to upgrade the quality of Specialization education by suggesting proper architectural planning of residential and educational space in those institutions.