Duplication or deletion of chromosome 17p11.2-p12 in CMT1 and HNPP peripheral neuropathy patients

Kim, Hyo-Sun,Jang, Young-Eun,Chung, Ki-Wha 公州大學校 基礎科學硏究所 2003 自然科學硏究 Vol.10 No.-

CMT와 HNPP 말초신경증은 가장 흔하게 발병하는 운동 및 감각 말초신경계의 선천성 질환이다. CMT1과 HNPP의 유전적 원인으로는 염색체 17p11.2-p12의 1.5 Mb 지역의 중복과 결실이 각각 50%이상과 70% 이상을 차지하는 것으로 알려졌다. 본 연구에서 한국인 CMT1 및 HNPP 환자를 대상으로 중복 및 결실을 조사하였는데, 31 CMT1 가족 중 13 가족에서 중복을 보였으며 (42%), 24 HNPP 가족 중 19 가족에서 결실을 보였다 (79%). 17p11.2-p12 중복을 보이는 CMT1A 환자가 HNPP 결실환자보다 발병 연령, 발병 기간, 근육 이양성 및 족 기형성에서 훨씬 심한 증상을 보였다. Charcot-Marie-Tooth disease (CMT) and hereditary neuropathy with liability to pressure palsies (HNPP) are most common inherited motor and sensory peripheral neuropathies. The majority of CMT1 patients have a 1.5 Mb duplication in chromosome 17p11.2 while most HNPP patients have a deletion of the same region. In the analysis of Korean CMT1 and HNPP patients, each HNPP deletion and CMT1A duplication was observed from 79% (19 families) among 24 HNPP families and 42% (13 families) among 31 CMT1 families. CMT1A duplication patients showed more severe clinical symptoms than HNPP deletion patients, when we examined oneset age, disease duration, muscular atrophy, foot deformity and scoliosis.

청각장애초등학생을 위한 음악교육프로그램 개발 연구

이드보라ㆍ남선화ㆍ정미라(Debora LeeㆍNam Sun WhaㆍJeong Mi ra) 한국특수교육학회 2016 특수교육학연구 Vol.50 No.4

쌓기 활동에서 유아들의 친 사회적 행동 출현에 대한 맥락적 이해

박화윤,마지순,최재숙 한국영유아보육학회 2002 한국영유아보육학 Vol.0 No.31

The purpose of this ethnographic study is to explore the emergent context of prosocial behavior and to find the children's character promoting of prosocial that within the area of block. The result are as follows: 1) It appeared that emergent context of prosocial; behavior is completion of structures, participation of symbolic play using them and clean-up. 2) It appeared that children's character promoting prosocial behavior that appearence of altruism by children's perspective-taking, exchage of idea and problem-solving.

X-線 廻折方法에 依한 Silicon의 構造 硏究

李善鏞,金永銓,尹和重,徐日煥 충남대학교 자연과학연구소 1982 忠南科學硏究誌 Vol.9 No.1

The crystal structure of silicon has been determined by X-ray powder diffraction study (Cu Kα radiation). The unit cell is cubic (diamond-type), F(2/d)3, with a=5.42 A˚, V=159.22 A˚^3, z=8, D_c=2.34gr/㎤. The structure was solved by graphical method using eleven powder diffraction data. The experimental and theoretical integrated intensities of the reflecting planes are in good agreement with each other. The silicon atoms have tetrahedral arrangement to form covalent bonds with four other atoms. The nearest interatomic distance is 2.34Å.

영구임대주택 빈곤모자가정의 삶의 질과 사회복지 욕구에 관한 연구

최선화,황성철 新羅大學校 1997 論文集 Vol.43 No.-

Given the magnitude of problems encountered by poverty-stricken mother-headed families and the significant impact that the families will have on their children, investigation on quality of life and specific welfare needs of the families is of an urgent need. Although previous research on the mother-headed families focused on the various aspects of living arrangement and some of the problems that those families have, most of them heavily relied on dada generated by social survey research. Using qualitative dada gathered through the grounded theory research method, this study highlights subjective meanings of quality of life perceived by the respondents and identifies subsequent social welfare needs of the target population. The result of this study shows that among the 18 respondents who participated in our research, one category of respondents perceived their current life as "lining in hell" which is expressed by the terms of hardship, misgiving, sorrow, broken-heart while the other perceived it as "self-sufficient" which is expressed by the terms of a little fortunate, satisfied, good stroke from others. The former includes persons who have server economic and health problems as well as the problems of family relationship especially with their children. however, the latter includes persons who are currently employed and have no serious health problems. Factors such as the degree to which their children's academic performance in school is acceptable and their religious beliefs are strong enough are significantly related to the positive and negative perceptions or their current life. In conclusion, economic, health, and educational needs of the poverty-stricken mother-headed families are found to be important, Welfare policy and social work services must be arranged to cope with those unment needs of the vulnerable families. Building an informal helping network as a specific intervention method of social work has been strongly recommended along with the changed role of social welfare centers in delivering services for those families. The issue of empowerment and feministic counseling have also been discussed in this article.

TV광고의 효과와 시청행위와의 상관관계에 관한 연구

金善化 釜山工業大學校 1990 論文集 Vol.32 No.-

Many scholars and practical businessmen argue about the drawing-up of TV commercials message. The scientific studies on TV cover the wide range of the branches of sciences, the methods of study and aims. But the stream of the study of TV is in social sciences, the main methods are social scientific and the aims have relation to do with social effect of TV. The positive study on TV, to say nothing of, needs an enormous financial support and takes so much time. And it is hard to approach. But its results are very reliable and are, I think, very important in the aspect of practical effect and the basic understanding on human cognition. Though TV takes very important role in economy and everyday life, the scientific study on using TV practically is very poor. It becomes clear that, generally most studies on TV, especially on commercials are almost useless in making various decisions on dynamics of time, conceptial and artistic aspect which determines the success of performance. We have seen general problems in the study of TV watching on the basis of positive researches. The main points may be summarized as follows. 1st. TV-watching constitues a part of family ecology according to which we can set up the object and effective method of commercial appeal. 2nd. We should design visual image, text and commercial logos with taking the distance and angle between the watcher and TV into account. 3rd. We should use audio monitoring in the way which call our attention from visuall inattention. 4th. The contents should be made with the consideration of the adequate degree of understanding according to age by the principle of comprehension guided attention.

社會事業機關에서의 保護觀察制度

文宣和 부산대학교 사회과학대학 1983 社會科學論叢 Vol.2 No.1

This article is aimed toward finding how a probation system and methods can be applied to a social work agency, in particular community welfare center. This investigation is composed of the following three parts : the general understanding of probation system, the position and role of social work I probation systems, and the participation of community welfare centers in probation practice. To this end I describe the history and practice of the probation system in such countries as the United States, England, and Japan. Then I examine how a social work agency can accomplish its own probationary function in Korea in three perspectives. First, it is desirable for aprivate agency to be to some extent in charge of probation practice because probation systems hardly seem to be worked out well under the control of the government. It's program has to be originated and administered by private agencies but financed by the public. Second, it is advisable that probation programs be changed. They have been oriented to work training, but they should be turned into counseling for jobs, strengthening the relationship between the ex-criminal sand business bommunity, and having seminars so that citizens and employers are willing to accept the disadvantaged people. Lastly, probation systems must be privately run in terms of selecting professional workers. The government has strict regulations on employing experts. Therefore, social work agencies are encouraged to take charge of probation for choosing proper personnel because correction work with human beings usually on one's basic values and philosophy.

거제시 노인생활실태분석 및 노인복지 발전방안

문선화,김기태,윤은경 釜山大學校 社會福祉硏究所 1999 社會福祉硏究 Vol.9 No.-

장애아통합보육에 대한 교사인식 연구

문선화,이선애 한국영유아보육학회 2003 한국영유아보육학 Vol.0 No.33

The purpose of this study was to investigate the factors that affect of integrated day care services including the efficiencies, problems and preparations to be providing this programs to both regular and exceptional children. The factors are classified with personnel related this service and day care facilities. The 112 persons out of 170 were responded for this research and their background was the day care teachers, special educators, PT/OT, and social workers who are directly or indirectly working with either regular or exceptional children at the regular day care centers, the center for the handicapped children only and the center for the integrated facilities. The results of this research findings are as follows: First, children whether they are disabilities or not helping each other. The number of children per a teacher and in a classroom were overcrowded, but guidelines or restrictions and regulations to the facilities are not adequately established. Second, the respondents' licenses vary from different resources and purposes, so it would be provided sometimes insufficient services in need of both regular and handicapped children. Third, integrated day care centers showed rather a high tendency of sufficient services than other day care programs. Fourth, teacher's age, kind of licenses and type of day care centers are influential factors affecting providing services to the children, but factors had feeble influence on the efficiencies and preparations of integrated day care.

사회병리적 현상으로서의 청소년 집단 따돌림의 문제와 원인

문선화 釜山大學校 社會福祉硏究所 2002 社會福祉硏究 Vol.11 No.-