Design and Shape Control Ability Simulation of New Generation Varying Contact Length Backup Roll in Hot Rolling

Wenquan Sun,Jian Shao,Anrui He 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.4

Backup roll technology plays an important role in hot strip mill shape control. Varying contact length backup roll (VCR) technology in hot strip mill can increase transverse stiffness of loaded gap, heighten control effect of roll bending, and improve distribution of contact force between backup roll and work roll. However it appears to lack coordination with high-order curve work roll. A new objective function of new generation varying contact length backup roll (VCR plus) design curve is established with considering high-order work roll contour, and simulation is carried out to verify the effectiveness of VCR plus by a two dimensional variable thickness finite element method. The result shows that distribution of contact force between backup roll and work roll is more even in VCR plus technology, and which can extend the useful life of backup roll.

Laboratory and field evaluation of the repellency of six preservatives to red imported fire ants (Hymenoptera: Formicidae)

Wenquan Qin,Hongpeng Xiong,YuzhenWen,XiujunWen,HuiWang,Yihan Fang,TaoMa,Zhaohui Sun,Xiaoyang Chen,Cai Wang 한국응용곤충학회 2017 Journal of Asia-Pacific Entomology Vol.20 No.2

Baiting is widely applied for the detection and control of the red imported fire ants, Solenopsis invicta Buren. Adding preservatives into baits would prevent microbial contamination during production and storage, and might extend period of bait attractiveness in the field. However, it is not known if preservatives are repellent to S. invicta. In the present study, potential effects of six commonly used preservatives (potassiumsorbate, sodium benzoate, sodium diacetate, sodium dehydroacetate, calcium propionate, and nisin) on the foraging behaviors of S. invicta foragers were evaluated under laboratory and field conditions. Four-choice tests (laboratory study) showed that the number of foraging ants on the preservative-treated (immersed in 2000-, 5000-, or 10,000-ppm solution for 30 min) and control (immersed in distilled water for 30 min) food was similar, with an exception of sodium dehydroacetate, which significantly decreased the number of foraging ants at the three tested concentrations. Interestingly, 46%, 58% and 71% of the food items treated with 2000-, 5000- and 10,000- ppm solutions of sodium dehydroacetate were buried with soil particles, respectively, whereas only 17% of the control food was similarly buried. Multiple-choice tests (field study) showed that food treated with the 5000- or 10,000-ppm solution of sodium dehydroacetate attracted significantly fewer S. invicta workers compared to other preservatives and the controls. Our study showed that the use of sodiumdehydroacetate should be avoided during the production of aqueous-based or liquid baits against S. invicta.

Combined multi-predict-correct iterative method for interaction between pulsatile flow and large deformation structure

Wang, Wenquan,Zhang, Li-Xiang,Yan, Yan,Guo, Yakun Techno-Press 2012 Coupled systems mechanics Vol.1 No.4

This paper presents a fully coupled three-dimensional solver for the analysis of interaction between pulsatile flow and large deformation structure. A partitioned time marching algorithm is employed for the solution of the time dependent coupled discretised problem, enabling the use of highly developed, robust and well-tested solvers for each field. Conservative transfer of information at the fluid-structure interface is combined with an effective multi-predict-correct iterative scheme to enable implicit coupling of the interacting fields at each time increment. The three-dimensional unsteady incompressible fluid is solved using a powerful implicit time stepping technique and an ALE formulation for moving boundaries with second-order time accurate is used. A full spectrum of total variational diminishing (TVD) schemes in unstructured grids is allowed implementation for the advection terms and finite element shape functions are used to evaluate the solution and its variation within mesh elements. A finite element dynamic analysis of the highly deformable structure is carried out with a numerical strategy combining the implicit Newmark time integration algorithm with a Newton-Raphson second-order optimisation method. The proposed model is used to predict the wave flow fields of a particular flow-induced vibrational phenomenon, and comparison of the numerical results with available experimental data validates the methodology and assesses its accuracy. Another test case about three-dimensional biomedical model with pulsatile inflow is presented to benchmark the algorithm and to demonstrate the potential applications of this method.

Application of Design Thinking in Modern Educational Practice

Ren Wenquan,고정훈 한국상품문화디자인학회 2024 상품문화디자인학연구 Vol.76 No.-

This paper comprehensively explores the application of design thinking in contemporary educational practices and its pivotal role in addressing key challenges in modern education. With the rapid societal changes, traditional educational models have exhibited a series of limitations and issues. Therefore, this research not only focuses on applying the principles of design thinking but also aims to enhance the overall quality of education and learning experiences. By integrating successful experiences from various domains, the study delves into how to adeptly incorporate the methods and principles of design thinking into the field of education to foster innovation and effective problem-solving. In the process of expanding the application of design thinking in education, the research emphasizes the importance of a user-centric approach, advocating for educators to prioritize individual student needs. This includes deepening the understanding of student requirements, fostering flexible teaching strategies, and collaborating across disciplines to create comprehensive and engaging educational solutions. The research highlights the significance of iterative processes, advocating for a culture that views failure as an opportunity for learning and improvement. Additionally, it explores the impact of artificial intelligence (AI) on education, delving into its potential benefits and challenges, including how AI technologies enhance personalized learning experiences, and addressing concerns related to job displacement and the ethical considerations of AI in education. The study underscores the importance of continuous improvement and evaluation, advocating for the establishment of effective student feedback loops to guide ongoing adjustments to curriculum and teaching methods. This research aims to provide comprehensive insights, offering practical recommendations to navigate the challenges of modern education, guiding educational practitioners and policy makers in fostering an innovative, student-centric, and adaptive educational environment. Through this in-depth exploration, the study seeks to meaningfully contribute to the ongoing evolution of the contemporary education landscape.

Plug-and-Play Nanorization of Coarse Black Phosphorus for Targeted Chemo-photoimmunotherapy of Colorectal Cancer

Ou, Wenquan,Byeon, Jeong Hoon,Thapa, Raj Kumar,Ku, Sae Kwang,Yong, Chul Soon,Kim, Jong Oh American Chemical Society 2018 ACS NANO Vol.12 No.10

<P>Because of their extraordinary physical properties and biocompatibility, black phosphorus (BP) nanosheets (NSs) have been intensively employed in chemo-phototherapies, such as plasmonic inorganic nanoparticles or graphene NSs, over the past few years. However, most biomedical studies using BP NSs are only concerned with the optical property of BP NSs to repeatedly demonstrate chemo-phototherapeutic efficacies, although BP NSs have different properties from inorganic nanoparticles or graphene NSs, such as corrugated crystal structure, hydrophilicity, and biodegradability. Moreover, it is still a challenging issue to efficiently fabricate uniform BP NSs for clinical translation because of the top-down nature of fabrication, despite the easy preparation of coarse BP flakes. It is thus essential to explore their most suitable bioapplications as well as suggest an easy-to-access strategy to produce uniform BP NSs for realization as advanced therapeutic materials. To rationalize these issues, this report introduces a plug-and-play nanorization, ultrasonic bubble bursting, of coarse BP flakes for continuous BP NS production, and the resulting uniform NSs (∼40 nm lateral dimension, ∼0.15 polydispersity index) were used as base materials to load drug (doxorubicin), targeting agent (chitosan-polyethylene glycol), and cancer growth inhibitor (programmed death ligand 1 and small interfering RNA) for achieving efficacious chemo-photoimmunotherapy of colorectal cancer.</P> [FIG OMISSION]</BR>

Regulatory T cell-targeted hybrid nanoparticles combined with immuno-checkpoint blockage for cancer immunotherapy

Ou, Wenquan,Thapa, Raj Kumar,Jiang, Liyuan,Soe, Zar Chi,Gautam, Milan,Chang, Jae-Hoon,Jeong, Jee-Heon,Ku, Sae Kwang,Choi, Han-Gon,Yong, Chul Soon,Kim, Jong Oh Elsevier 2018 Journal of controlled release Vol.281 No.-

<P><B>Abstract</B></P> <P>Immunosuppression in tumor microenvironments induced by regulatory T (Treg) cells is regarded a critical mechanism of tumor immune escape and poses a major impediment to cancer immunotherapy. In this study, we developed tLyp1 peptide-conjugated hybrid nanoparticles for targeting Treg cells in the tumor microenvironment. The tLyp1 peptide-modified hybrid nanoparticles presented good stability and effective targeting to Treg cells, and they enhanced the effect of imatinib in downregulating Treg cell suppression through inhibition of STAT3 and STAT5 phosphorylation. In addition, an <I>in vivo</I> study revealed high tumor accumulation of the hybrid nanoparticle. Specifically, prolonged survival rate, enhanced tumor inhibition, reduced intratumoral Treg cells, and elevated intratumoral CD8<SUP>+</SUP> T cells against tumor were observed when combined with checkpoint-blockade by using anti-cytotoxic T-lymphocyte antigen-4 antibody. This study provided groundwork for a repertoire of nanoparticle-based drugs for targeting and modulating Treg cell function in the tumor microenvironment and for improving antitumor immunotherapy.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

원격 헬스 서비스를 위한 JSON 기반의 OCF IoTivity 메시지 전송 연구

김문권 ( Wenquan Jin ),김형준 ( Hyong-jun Kim ),김도현 ( Dohyeun Kim ) 한국정보처리학회 2017 한국정보처리학회 학술대회논문집 Vol.24 No.2

최근 통신, 전자 기술의 발전으로 헬스 서비스를 언제 어디서나 사용자에게 제공할 수 있다. 다양한 e-헬스 디바이스들과의 연동을 위하여 본 논문에서는 OCF IoTivity 프레임워크을 e-헬스 디바이스에 적용하고 JSON 기반의 메시지를 생성하여 전송하는 기법을 제안한다. 이 기법은 e-헬스 시스템에서 인터넷을 통하여 원격 헬스 서비스를 제공하는데 사용할 수 있다.

Discrete Hopfield Neural Networks for Evaluating Service Quality of Public Transit

Jinxing Shen,Wenquan Li 보안공학연구지원센터 2014 International Journal of Multimedia and Ubiquitous Vol.9 No.2

Research on the Comprehensive Control Strategy of Over-welding Based on Decoupling- Design for Tandem Cold Mills

Jian Shao,Wenquan Sun,Anrui He 보안공학연구지원센터 2015 International Journal of u- and e- Service, Scienc Vol.8 No.3

The strategies of the welding seam dynamic passing control and feasible loose edge rolling technology are put forward. In the process of cold mill welding, by dynamic regulation roll-gap, bending force and stand speed. The control strategy of reducing tensions between stands and strip edge is achieved. At the same time, the decoupling control strategy of plate shape and thickness can reduce the influence of roll-gap on plate shape and of bending force and stand speed on the steel thickness. Simulation analysis and practical application show that the technology effectively reduces the occurrence of steel strip fracture of tandem cold mill units.

The flow and heat transfer performances of magnetic nanofluid in a duct in presence of magnetic fields with different direction

Cuihua Wang,Duo Rong,Wenquan Zhang,Bin Gong,Jianhua Wu 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.9

The flow and heat transfer characteristics of magnetic nanofluids in a circular channel under the action of magnetic fields were studied through numerical simulation based on the finite element method. The results show that there are obvious secondary vortices on the cross-section, and a swirling flow is formed in the duct under the coupling effects of the magnetic field, velocity distribution, and thermal variations which destroys the boundary layer, accelerates the mixing of fluids, and enhances heat transfer. In the studied range, the maximum heat transfer coefficient can be increased by 102.65 %, and the maximum comprehensive heat transfer factor J is 1.69 compared to the ferrofluid not affected by the external magnetic field. In addition, the effect of enhancing heat transfer gradually decreases with the increase of θ, until heat transfer is slightly inhibited when the magnetic field is parallel to the flow direction.