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      • KCI등재

        Application of adaptive local iterative filtering in axis trace purification of turbine generator rotor

        Wenbin Zhang,Jie Min,Yun Wang,Yasong Pu,Jie Jiang,Dewei Guo,Libin Yu 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.6

        In order to solve the problem that the measured axis trace is polluted by noise and can not reflect the real fault type of the turbine generator rotor, the adaptive local iterative filtering is applied to the purification of the axis trace of the generator rotor. As an adaptive mode decomposition method, adaptive local iterative filtering can adaptively decompose a complex original signal into a series of single components reflecting the wave nature of the signal, then, by calculating the correlation coefficient between the autocorrelation function of each decomposition component and the autocorrelation function of the original signal, the real intrinsic mode function is extracted, finally, the extracted intrinsic mode function is used to synthesize the signal to purify the axis trace. The simulation analysis and the purification results of the measured axis trace show that the adaptive local iterative filter can effectively avoid the false components in the decomposition process and is more favorable for extracting the signal features by introducing the Fokker-Planck equation to design the filter, compared with ensemble empirical mode decomposition, this method has better purification performance.

      • A Multicast Based Bandwidth Saving Approach for Wireless Live Streaming System

        Wenbin Jiang,Hai Jin,Xiaofei Liao,Zhi Yuan 보안공학연구지원센터 2008 International Journal of Smart Home Vol.2 No.1

        P2P based live streaming applications are growing up rapidly. However, when extending them to WLANs, the bandwidth bottleneck and the high rate of packet loss are usually the major stumbling blocks. To overcome this issue, a new wireless multicast agent mechanism (WiMA) based on the IP multicast scheme for buffer management and scheduling is proposed. First of all, a wireless agent selection method is presented to choose an appropriate agent for WiMA. Then this agent gains media data by interacting with wired neighbor peers as a common P2P node, and transmits these data to other wireless peers in the WLAN by means of multicast pushing and multicast patching. A normal wireless peer requests data according to the strategy of "emergent ones first". Experimental results show that the approach proposed can significantly save bandwidth in WLANs with acceptable start delay and satisfied playing continuity.

      • KCI등재

        PROM2 promotes gemcitabine chemoresistance via activating the Akt signaling pathway in pancreatic cancer

        Wenbin Li,Yue Zhu,Kelin Zhang,Xianhuan Yu,Haoming Lin,Wenrui Wu,Yaorong Peng,Jian Sun 생화학분자생물학회 2020 Experimental and molecular medicine Vol.52 No.-

        In recent years, the deoxycytidine analogue gemcitabine (2′,2′,-difluorodeoxycytidine) has become the first-line chemotherapeutic agent for patients with pancreatic cancer. However, due to the intrinsic resistance of pancreatic cancer cells, gemcitabine-based chemotherapy yields limited disease control, with >85% disease progression at 6 months from diagnosis. Therefore, elucidating the mechanisms of chemoresistance is a critical step in improving cancer therapy, especially for the treatment of pancreatic cancer. We show PROM2, a transmembrane glycoprotein, is ubiquitously upregulated in pancreatic cancer cell. We also found higher PROM2 expression is associated with shortened overall and disease-free survival times in patients diagnosed with pancreatic cancer. We provide evidence that PROM2 promotes chemoresistance to gemcitabine both in vivo and in vitro. Mechanistically, we demonstrate that PROM2 could directly interacted with Akt and activates the Akt signaling pathway, which thus inhibiting gemcitabineinduced apoptosis. As further evidence, we show PROM2 expression and Akt phosphorylation both promote gemcitabine chemoresistance, and cause poorer survival in clinical samples with pancreatic cancer. Combining gemcitabine with the Akt inhibitor MK-2206 facilitated significant tumor shrinkage and dramatically elevated the survival status in mice xenografted with pancreatic cancer cells. Our findings not only establish PROM2 as a novel positive regulator of the Akt signaling pathway and a candidate prognostic indicator of gemcitabine response, but also provide a neo-therapeutic approach for patients resistant to gemcitabine treatment.

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      • KCI등재

        Molecular characterization of a sweet potato stress toleranceassociated trehalose-6-phosphate synthase 1 gene (IbTPS1) in response to abiotic stress

        Wenbin Wang,Huan Yu,김호수,Yanxin Yang,Xiangpo Qiu,곽상수 한국식물생명공학회 2019 Plant biotechnology reports Vol.13 No.3

        Trehalose-6-phosphate synthase (TPS) plays an important regulatory role in the response of plants to multiple abiotic stresses. However, our knowledge of the stress tolerance functions of TPS genes in sweet potato (Ipomoea batatas [L.] Lam) remains limited. In the present study, we isolated and functionally characterized the sweet potato gene encoding TPS1, IbTPS1. Sequence analysis showed that IbTPS1 belongs to class I TPS proteins and harbors highly conserved acceptor (glucose- 6-phosphate [Glc6P]) and donor (uridine diphosphoglucose [UDP-Glc]) binding sites. The IbTPS1 gene showed the highest level of constitutive expression in leaves and storage roots of sweet potato plants and was induced by several environmental stresses including drought, salt, and heat shock. The IbTPS1 protein might be localized to the cytosol. Complementation assay of yeast tps1Δ and tps1Δtps2Δ growth-defective mutants confirmed the TPS activity of IbTPS1, and truncation of the N-terminal extension of IbTPS1 (ΔNIbTPS1) increased the catalytic activity of the protein. Additionally, expression of IbTPS1 in yeast conferred abiotic stress tolerance to dehydration, salinity, and oxidation, and expression of ΔNIbTPS1 further enhanced the tolerance to abiotic stresses. The results of this study advance our understanding of the functions of IbTPS1 under abiotic stress conditions. Our results suggest that the IbTPS1 gene is an excellent candidate for improving the stress tolerance of different crop plants.

      • KCI등재

        A Multiscale Analysis Method for Predicting the Transverse Mechanical Properties of Unidirectional Fibre-reinforced Composites

        Wenbin Jia,Lei Fang,Zhi Chen,Kai Zhao,Hongmei Huang,Lei Pan 한국섬유공학회 2020 Fibers and polymers Vol.21 No.6

        Mechanical property prediction methods for composites are very important as theoretical tools for engineeringstructural design. To more accurately capture the transverse mechanical properties of composites, a multiscale analysismethod is developed in this paper. The multiscale analysis method includes three scales: (1) At the microscale, a microscopiccohesive model based on atomic potential energy is established for the interface; (2) At the mesoscale, a unit cell model isestablished for the fibre, matrix and interface; and (3) At the macroscale, the homogenization method, failure criteria anddamage degradation models are used for predicting the transverse mechanical properties. Subsequently, the transversemechanical properties and the damage evolution process are simulated with the multiscale analysis method. A comparisonbetween the simulations and experiments shows that the maximum error of the predicted transverse modulus and transversestrength is -4.45 % and -12.05 %, respectively. Finally, the effects of the interfacial strength on the macroscopic transversemechanical properties and the damage onset are analysed. The following conclusions are drawn from the simulation results:(1) The interfacial strength has a more significant effect on the transverse strength and ultimate strain than on the transversemodulus; (2) Decreasing the interfacial strength has a greater effect on the transverse modulus, strength and ultimate strainthan increasing the interfacial strength; and (3) The interfacial strength can change the damage onset.

      • KCI등재

        Energy Simulation Framework Integrated with Green Manufacturing-Enabled PLM Information Model

        Wenbin Zhao,정진우,노상도,John T. Yee 한국정밀공학회 2015 International Journal of Precision Engineering and Vol.2 No.3

        Manufacturing industry has been facing tremendous pressure on environmental regulations like the reduction of pollutants, e.g., carbon dioxide. Limited natural resources have driven manufacturing companies to seek ways to reduce energy consumption for daily production. Manufacturing industry needs to consider sustainability for green manufacturing during the entire product life cycle. Conventional product life cycle management has not considered energy consumption with respect to product manufacturing. This paper proposes a new product life cycle management information model by considering the sustainability aspects. And a framework is presented to conduct energy simulation for analyzing the impact of sustainability on manufacturing. Analysis results show that the energy simulation using the sustainability-enabled product life cycle management information model could assist the manufacturing industry to save energy.

      • KCI등재

        Electromagnetic Counter-recoil Mechanism Based on Adaptive Sliding Mode Control

        Wenbin Yu,Guolai Yang,Liqun Wang,Lei Li,Hongyi Zhang 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.9

        Traditional counter-recoil machines always have problems of difficulty in adjusting the movement process flexibly, maintenance difficulties, and so on. To end these, this paper proposes a new electromagnetic counterrecoil scheme using cylindrical linear motors. Firstly, the mathematical expression of counter-recoil movement under the linear motor is formulated, and the ideal movement trajectory is designed using the piecewise polynomial of velocity based on acceleration. To obtain a better performance, of the motor controller, a composed approach of an adaptive sliding mode control based on barrier function (BFASMC) and the finite-time disturbance observer (FTDO) is introduced into the modeling and computation. The stability of the controller is proved by establishing the Lyapunov function. The new adaptive laws based on the barrier function effectively make up for the shortcomings of the exponential function and improves control chattering. At last, the new scheme is simulated. The results show that it has a strong robustness and anti-interference ability.

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