A Novel Resource Scheduling Scheme for CoMP Systems

( Wen`an Zhou ),( Jianlong Liu ),( Yiyu Zhang ),( Chengyi Yang ),( Xuhui Yang ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.2

Coordinated multiple points transmission and reception (CoMP) technology is used to mitigate the inter-cell interference, and increase cell average user normalized throughput and cell edge user normalized throughput. There are two kinds of radio resource schedule strategies in LTE-A/5G CoMP system, and they are called centralized scheduling strategy and distributed scheduling strategy. The regional centralized scheduling cannot solve interference of inter-region, and the distributed scheduling leads to worse efficiency in the utilize of resources. In this paper, a novel distributed scheduling scheme named 9-Cell alternate authorization (9-CAA) is proposed. In our scheme, time-domain resources are divided orthogonally by coloring theory for inter-region cooperation in 9-Cell scenario [6]. Then, we provide a formula based on 0-1 integer programming to get chromatic number in 9-CAA. Moreover, a feasible optimal chromatic number search algorithm named CNS-9CAA is proposed. In addition, this scheme is expanded to 3-Cell scenario, and name it 3-Cell alternate authorization (3-CAA). At last, simulation results indicate that 9/3-CAA scheme exceed All CU CoMP, 9/3C CU CoMP and DLC resource scheduling scheme in cell average user normalized throughput. Especially, compared with the non-CoMP scheme as a benchmark, the 9-CAA and 3-CAA have improved the edge user normalized throughput by 17.2% and 13.0% respectively.

Analysis of differential proteins in two different wing‐types of female Nilaparvata lugens

An‐Wen Liang,Ting-Ting LIU,Zi-Qiang Liang,Fang-Hai Wang 한국곤충학회 2018 Entomological Research Vol.48 No.3

Nilaparvata lugens (stal) is a rice pest and contains long‐winged and short‐winged varieties, called the wing differentiation. This study compared the protein profiles of the two wing‐types in females and two wing‐disc types 5th‐instar females by two‐dimensional electrophoresis analysis. We detected 172 and 174 protein spots in adults and 5th‐instar nymphs, respectively. The number of proteins with higher content in the long‐winged (disc) individuals is much more than that in the short‐winged (disc) individuals. A total of 32 differential protein spots were found, of which 20 were successfully identified. Their main function is about catabolic process, fiber and nucleoside binding, and they constitute 52 protein–protein interactions, which is around the glycolysis as the core. These results enrich the research on the protein Level in wing development, and provide more references for future studies.

A Simulated Culture? : Cultural Learning Impact of the One-day Study Tour

Li-Jiuan Lilie Tsay,An-Wen Deng,Su-Yuan Lien 세계문화관광학회 2008 International Journal of Culture and tourism Resea Vol.1 No.1

One-day study tour in Taiwan began its establishment in early 2007, inspired by the An-San English Village in Seoul, in order to help students learn English quickly and efficiently. Different situational classrooms, such as a clinic, a hotel, a travel agency etc., are set up and manned with native teachers to teach students appropriate conversations accordingly. The main ideas of setting up such an English immersion program are to provide students with enough exposure to an English speaking environment and the culture related. In language learning, culture is one of the key elements which often determine students' learning interest and therefore cannot be neglected. In this study, based on the previous literature research, a model which suggests the relationships among learners' English ability (EA), learning interest (LI) and the situational classroom teaching (SCT) is discussed and explored. The purpose of the study is to investigate whether the simulated culture in different classroom settings could enhance students' English ability and their learning interest through the examination of the model suggested.

An Emission-Aware Day-Ahead Power Scheduling System for Internet of Energy

( Chenn-jung Huang ),( Kai-wen Hu ),( An-feng Liu ),( Liang-chun Chen ),( Chih-ting Chen ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.10

As a subset of the Internet of Things, the Internet of Energy (IoE) is expected to tackle the problems faced by the current smart grid framework. Notably, the conventional day-ahead power scheduling of the smart grid should be redesigned in the IoE architecture to take into consideration the intermittence of scattered renewable generations, large amounts of power consumption data, and the uncertainty of the arrival time of electric vehicles (EVs). Accordingly, a day-ahead power scheduling system for the future IoE is proposed in this research to maximize the usage of distributed renewables and reduce carbon emission caused by the traditional power generation. Meanwhile, flexible charging mechanism of EVs is employed to provide preferred charging options for moving EVs and flatten the load profile simultaneously. The simulation results revealed that the proposed power scheduling mechanism not only achieves emission reduction and balances power load and supply effectively, but also fits each individual EV user’s preference.

Research on the Technology of Alternative Continuous Wide Spectral Spatial Heterodyne Spectrometer

Wenli Zhang,Fengchun Tian,Zhenzhen Zhao,An Song,Li Zhang 한국광학회 2017 Current Optics and Photonics Vol.1 No.4

An innovative system for the alternative continuous wide spectral spatial heterodyne spectrometer (ACWSSHS)is proposed. The relationship between the ACWS-SHS and the wide spectral spatial heterodynespectrometer (WS-SHS) at the resolution limit, the spectral range, the grating diffraction efficiency and theinterference fringes contrast ratio has been analyzed theoretically. Through the comparison of the theoreticalanalysis and simulation results, it is found that the two systems for the WS-SHS and the ACWS-SHShave the same resolution limit and spectral range, which are  and , while in the ACWS-SHS systemthe critical diffraction efficiency of echelle grating is 68.39% and the critical contrast ratio of interferencefringes is 0.4135, which is much better than the performance of the WS-SHS system. Therefore, the ACWSSHSreduces the high requirements for the precision of equipment and expands the application field ofSHS effectively.

Metabotyping of the <i>C. elegans sir-2.1</i> Mutant Using <i>in Vivo</i> Labeling and ¹³C-Heteronuclear Multidimensional NMR Metabolomics

An, Yong Jin,Xu, Wen Jun,Jin, Xing,Wen, He,Kim, Hyesook,Lee, Junho,Park, Sunghyouk American Chemical Society 2012 ACS chemical biology Vol.7 No.12

<P>The roles of <I>sir-2.1</I> in <I>C. elegans</I> lifespan extension have been subjects of recent public and academic debates. We applied an efficient workflow for <I>in vivo</I><SUP>13</SUP>C-labeling of <I>C. elegans</I> and <SUP>13</SUP>C-heteronuclear NMR metabolomics to characterizing the metabolic phenotypes of the <I>sir-2.1</I> mutant. Our method delivered sensitivity 2 orders of magnitude higher than that of the unlabeled approach, enabling 2D and 3D NMR experiments. Multivariate analysis of the NMR data showed distinct metabolic profiles of the mutant, represented by increases in glycolysis, nitrogen catabolism, and initial lipolysis. The metabolomic analysis defined the <I>sir-2.1</I> mutant metabotype as the decoupling between enhanced catabolic pathways and ATP generation. We also suggest the relationship between the metabotypes, especially the branched chain amino acids, and the roles of <I>sir-2.1</I> in the worm lifespan. Our results should contribute to solidifying the roles of <I>sir-2.1</I>, and the described workflow can be applied to studying many other proteins in metabolic perspectives.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/acbcct/2012/acbcct.2012.7.issue-12/cb3004226/production/images/medium/cb-2012-004226_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/cb3004226'>ACS Electronic Supporting Info</A></P>

A longitudinal analysis with CA-125 to predict overall survival in patients with ovarian cancer

An Jen Chiang,Jiabin Chen,Yu-Che Chung,Huan-Jung Huang,Wen Shiung Liou,Chung Chang 대한부인종양학회 2014 Journal of Gynecologic Oncology Vol.25 No.1

Objective: The objective of this study was to explore the association of longitudinal CA-125 measurements with overall survival (OS) time by developing a flexible model for patient-specific CA-125 profiles, and to provide a simple and reliable prediction of OS. Methods: A retrospective study was performed on 275 patients with ovarian cancer who underwent at least one cycle of primary chemotherapy in our institute. Serial measurements of patients’ CA-125 levels were performed at different frequencies according to their clinical plans. A statistical model coupling the Cox proportional hazards and the mixed-effects models was applied to determine the association of OS with patient-specific longitudinal CA-125 values. Stage and residual tumor size were additional variables included in the analysis. Results: A total of 1,601 values of CA-125 were included. Longitudinal CA-125 levels, stage, and the residual tumor size were all significantly associated with OS. A patient-specific survival probability could be calculated. Validation showed that, in average, 85.4% patients were correctly predicted to have a high or low risk of death at a given time point. Comparison with a traditional model using CA-125 half-life and time to reach CA-125 nadir showed that the longitudinal CA-125 model had an improved predicative value. Conclusion: Longitudinal CA-125 values, measured from the diagnosis of ovarian cancer to the completion of primary chemotherapy, could be used to reliably predict OS after adjusting for the stage and residual tumor disease. This model could be potentially useful in clinical counseling of patients with ovarian cancer.

MST1R as a potential new target antigen of chimeric antigen receptor T cells to treat solid tumors

Wen An,강주섭,오숙정,Ang Tu 대한약리학회 2023 The Korean Journal of Physiology & Pharmacology Vol.27 No.3

Although chimeric antigen receptor T cell (CAR-T) is a promising immunotherapy in hematological malignancies, there remain many obstacles to CART cell therapy for solid tumors. Identifying appropriate tumor-associated antigens (TAAs) is especially critical for success. Using a bioinformatics approach, we identified common potential TAAs for CAR-T cell immunotherapy in solid tumors. We used the GEO database as a training dataset to find differentially expressed genes (DEGs) and verified candidates using the TCGA database, obtaining seven common DEGs (HM13, SDC1, MST1R, HMMR, MIF, CD24, and PDIA4). Then, we used MERAV to analyze the expression of six genes in normal tissues to determine the ideal target genes. Finally, we analyzed tumor microenvironment factors. The results of major microenvironment factor analyses showed that MDSCs, CXCL1, CXCL12, CXCL5, CCL2, CCL5, TGF-β, CTLA-4, and IFN-γ were significantly overexpressed in breast cancer. The expression of MST1R was positively correlated with TGF-β, CTLA-4, and IFN-γ. In lung adenocarcinoma, MDSCs, Tregs, CXCL12, CXCL5, CCL2, PD-L1, CTLA-4, and IFN-γ were significantly overexpressed in tumor tissues. The expression of MST1R was positively correlated with TGF-β, CTLA-4, and IFN-γ. In bladder cancer, CXCL12, CCL2, and CXCL5 were significantly overexpressed in tumor tissues. MST1R expression was positively correlated with TGF-β. Our results demonstrate that MST1R has the potential as a new target antigen for treating breast cancer, lung adenocarcinoma, and bladder cancer and may be used as a progression indicator for bladder cancer.

Head-on Collision Between Two Envelope Solitary Waves in a Granular Medium

Wen-Qing Du,Jian-An Sun,Juan-Fang Han,Wen-Shan Duan,Yang-Yang Yang,Xin Jiang 한국물리학회 2019 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.75 No.11

We investigated the head-on collision between two envelope solitary waves. Head-on collisions between two envelope solitary waves are first discussed in one-dimension (1D) granular chains. The interesting result is that no phase shift or phase delay detected after the head-on collision between two envelope solitary waves. The maximum amplitude during the head-on collision between two envelope solitary waves is also found to be less than the sum of the amplitudes of the two envelope solitary waves, but is larger than the amplitude of the either of the envelope solitary waves.

Research of Evaluation Mechanism of Petrochemical Informatization Projects Based on AHPP

Feng’an Wen 보안공학연구지원센터 2014 International Journal of Hybrid Information Techno Vol.7 No.6

To address unreasonable planning process and imbalanced budget for informatization projects of petrochemical enterprises, this paper designs an informatization projects evaluation model. Analytic Hierarchy Process (AHP) is introduced to provide theoretical support. First, this paper conducts a hierarchical analysis to the decisive project factors in the informatization construction by constructing judgment set for the ladder-type hierarchical mode. Then, it calculates the weight for each factor and makes reasonable decision, which provides guidance to the implement of the informatization projects of petrochemical enterprises.