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      • Research on the Impact of Perfect Diary Offline Experience Marketing on Consumer Behavior

        Yue Wei(Yue Wei) 동북아경상학회 2022 동북아경상연구 Vol.3 No.2

        Purpose - In recent years, with the rapid improvement of China’s economy, technology, and consumption level, the beauty industry gradually occupies an important part of the national economy, and the demand for consumers’ spiritual level is also higher and higher. Design/Methodology/Approach - This paper focuses on the developing beauty product market in the era of the experience economy, selects the most representative perfect diary brand as an, example and finds the marketing problems of offline experience store of perfect diary brand from the perspective of experience marketing. Findings - This paper uses experiential marketing in the offline experience store of the perfect diary brand as the research object. Using SPSS statistical analysis method and questionnaire survey method, this paper deeply analyzes the industry status of the offline experience store of perfect diary brand, makes assumptions on the relationship between experiential marketing and consumer perceived value of the offline experience store of perfect diary brand, and analyzes the relationship among experience marketing, perceived value, and consumer behavior. Research Implications - Based on the experimental results, this paper puts forward a series of marketing suggestions to improve the market competitiveness and popularity of the perfect diary offline experiestorestore, and obtains marketing strategies according to the actual situation.

      • SCOPUSKCI등재

        Applications of a Deep Neural Network to Illustration Art Style Design of City Architectural

        ( Yue Wang ),( Jia-wei Zhao ),( Ming-yue Zheng ),( Ming-yu Li ),( Xue Sun ),( Hao Liu ),( Zhen Liu ) 한국정보처리학회 2024 Journal of information processing systems Vol.20 No.1

        With the continuous advancement of computer technology, deep learning models have emerged as innovative tools in shaping various aspects of architectural design. Recognizing the distinctive perspective of children, which differs significantly from that of adults, this paper contends that conventional standards may not always be the most suitable approach in designing urban structures tailored for children. The primary objective of this study is to leverage neural style networks within the design process, specifically adopting the artistic viewpoint found in children's illustrations. By combining the aesthetic paradigm of urban architecture with inspiration drawn from children's aesthetic preferences, the aim is to unearth more creative and subversive aesthetics that challenge traditional norms. The selected context for exploration is the landmark buildings in Qingdao City, Shandong Province, China. Employing the neural style network, the study uses architectural elements of the chosen buildings as content images while preserving their inherent characteristics. The process involves artistic stylization inspired by classic children's illustrations and images from children's picture books. Acting as a conduit for deep learning technology, the research delves into the prospect of seamlessly integrating architectural design styles with the imaginative world of children's illustrations. The outcomes aim to provide fresh perspectives and effective support for the artistic design of contemporary urban buildings.

      • KCI등재

        MiR-182-5p Knockdown Targeting PTEN Inhibits Cell Proliferation and Invasion of Breast Cancer Cells

        Yue-Sheng Zhao,Wei-Chao Yang,Hong-Wei Xin,Ji-Xia Han,Su-Gang Ma 연세대학교의과대학 2019 Yonsei medical journal Vol.60 No.2

        Purpose: Breast cancer (BC) is one of the most common malignant tumors, affecting a significant number of women worldwide. MicroRNAs (miRNAs) have been reported to play important roles in tumorigenesis. The aim of this study was to determine theroles of miR-182-5p in BC progression. Materials and Methods: The expressions of miR-182-5p and phosphatase and tensin homolog deleted on chromosome 10(PTEN) were measured in BC tissues and cells by quantitative real-time polymerase chain reaction or Western blot. Cell proliferationand invasion were detected by cell counting kit-8 assay and trans-well assay, respectively. The interaction between miR-182-5p and PTEN was probed by bioinformatics analysis, luciferase activity, and RNA immunoprecipitation. A murine xenograftmodel was established to investigate the role of miR-182-5p in BC progression in vivo. Results: An abundance of miR-182-5p was noted in BC tissues and cells. High expression of miR-182-5p was associated with poorsurvival. Abrogation of miR-182-5p inhibited cell proliferation and invasion in BC cells. Interestingly, PTEN was indicated as atarget of miR-182-5p, and its restoration reversed miR-182-5p-mediated promotion of proliferation and invasion of BC cells. Moreover, depletion of miR-182-5p suppressed tumor growth via up-regulating PTEN expression in the murine xenograft model. Conclusion: MiR-182-5p exhaustion blocked cell proliferation and invasion by regulating PTEN expression, providing a noveltherapeutic avenue for treatment of BC.

      • KCI등재

        Blind Source Separation of Instantaneous Mixture of Delayed Sources Using High-Order Taylor Approximation

        Wei Zhao,Zhi-Gang Yuan,Yue-hong Shen,Yufan Cao,Yimin Wei,Pengcheng Xu,Wei Jian 한국전자통신연구원 2015 ETRI Journal Vol.37 No.4

        This paper deals with the problem of blind source separation (BSS), where observed signals are a mixture of delayed sources. In reference to a previous work, when the delay time is small such that the first-order Taylor approximation holds, delayed observations are transformed into an instantaneous mixture of original sources and their derivatives, for which an extended second-order blind identification (SOBI) approach is used to recover sources. Inspired by the results of this previous work, we propose to generalize its first-order Taylor approximation to suit higher-order approximations in the case of a large delay time based on a similar version of its extended SOBI. Compared to SOBI and its extended version for a first-order Taylor approximation, our method is more efficient in terms of separation quality when the delay time is large. Simulation results verify the performance of our approach under different time delays and signal-to-noise ratio conditions, respectively.

      • KCI등재

        Robust Exponential H∞ Control for Autonomous Platoon against Actuator Saturation and Time-varying Delay

        Wei Yue,Liyuan Wang 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.6

        This paper is concerned with bidirectional autonomous platoon control with saturating actuator and timevarying delay. First, A new bidirectional platoon control system model is established, in which the effect of engine time uncertainty, actuator saturation and time-varying actuator delay is involved. Then, the robust exponential stability conditions of the platoon system are presented, only use information from its immediate neighbors. The theoretical results show that the proposed platoon controller would be able to safely maintain a smaller inter-vehicle spacing, less fuel and would be bidirectional string stable. Finally, some numerical simulations are provided to demonstrate the effectiveness and advantage of the presented methodology.

      • Implication of Polymorphisms in DNA Repair Genes in Prognosis of Hepatocellular Carcinoma

        Yue, Ai-Min,Xie, Zhen-Bin,Guo, Shu-Ping,Wei, Qi-Dong,Yang, Xiao-Wei Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

        XRCC1 genetic polymorphisms could be associated with increased risk of various cancer, including hepatocellular carcinoma (HCC), the fifth most common cancer. We here conducted a study to explore the role of selective SNPs of the XRCC1 and XPD genes in the prognosis of HCC. A total of 231 cases were collected, and genotyping of XRCC1 Arg194Trp, XRCC1 Arg399Gln, XPD Lys751Gln and XPD Asp312Asn was performed by duplex polymerase-chain-reaction with the confronting-two-pair primer method. Our findings indicated XRCC1 399Gln/Gln genotype was associated with a significant difference in the median survival time compared with patients carrying Arg/Trp and Arg/Arg genotypes, and individuals with XPD 751 Gln/ Gln genotype had a significantly greater survival time than patients carrying Lys/Lys and Lys/Gln genotypes. The Cox's regression analysis showed individuals carrying XRCC1 399Trp/Trp genotype had 0.55 fold risk of death from HCC than Arg/Arg genotype. Similarly, XPD 751Gln/Gln had a strong decreasein comparison to XPD Lys/Lys carriers with an HR of 0.34. These results suggest that polymorphisms in XRCC1 and XPD may have functional significance in the prognosis of HCC.

      • KCI등재

        Appropriate nitrogen application enhances saponin synthesis and growth mediated by optimizing root nutrient uptake ability

        Wei, Wei,Ye, Chen,Huang, Hui-Chuan,Yang, Min,Mei, Xin-Yue,Du, Fei,He, Xia-Hong,Zhu, Shu-Sheng,Liu, Yi-Xiang The Korean Society of Ginseng 2020 Journal of Ginseng Research Vol.44 No.4

        Background: Cultivation of medicinal crops, which synthesize hundreds of substances for curative functions, was focused on the synthesis of secondary metabolites rather than biomass accumulation. Nutrition is an important restrict factor for plant growth and secondary metabolites, but little attention has been given to the plasticity of nutrient uptake and secondary metabolites synthesis response to soil nitrogen (N) change. Methods: Two year-field experiments of Sanqi (Panax notoginseng), which can synthesize a high level of saponin in cells, were conducted to study the effects of N application on the temporal dynamics of biomass, nutrient absorption, root architecture and the relationships between these parameters and saponin synthesis. Results: Increasing N fertilizer rates could improve the dry matter yields and nutrient absorption ability through increasing the maximum daily growth (or nutrient uptake) rate. Under suitable N level (225 kg/ha N), Sanqi restricted the root length and surface and enhanced the root diameter and N uptake rate per root length (NURI) to promote nutrient absorption, but the opposite status of Sanqi root architecture and NURI was found when soil N was deficient. Furthermore, increasing N rates could promote the accumulation of saponin in roots through improving the NURI, which showed a significant positive relationship with the content of saponin in the taproots. Conclusion: Appropriate N fertilizer rates could optimize both root architecture and nutrient uptake efficiency, then promote both the accumulation of dry matter and the synthesis of saponins.

      • KCI등재

        Observer-based Fuzzy Adaptive Sliding Mode Control of IOCV with Actuator Faults and Saturation

        Wei Yue,Haoyang Shen,Liyuan Wang 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.11

        The control strategy for Internet of Connected Vehicles (IOCV) with unidentified actuator faults and saturation is examined in this study. The IOCV system is represented by a third-order nonlinear model that takes into account the unknown nonlinear dynamics with time-varying faults and saturation. A fuzzy adaptive sliding mode (FASM) controller with a nonlinear disturbance observer has been developed based on the new model, and it can concurrently achieve the control goals of string stability and individual vehicle stability with zero initial spacing error. In addition, a novel modified constant time headway (MCTH) is proposed to address string instability caused by nonzero starting conditions. In order to confirm the superiority, numerical simulation and experiment are tested on Matlab and the IOCV made of four Ackermann cars.

      • KCI등재

        RBM24 exacerbates bladder cancer progression by forming a Runx1t1/TCF4/miR-625-5p feedback loop

        Yin Yue-Wei,Liu Kai-Long,Lu Bao-Sai,Li Wei,Niu Ya-Lin,Zhao Chen-Ming,Yang Zhan,Guo Ping-Ying,Qi Jin-Chun 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-

        RNA–binding motif protein 24 (RBM24) acts as a multifunctional determinant of cell fate, proliferation, apoptosis, and differentiation during development by regulating premRNA splicing and mRNA stability. It is also implicated in carcinogenesis, but the functions of RBM24 in bladder cancer (BC) remain unclear. In the present study, we revealed that RBM24 was upregulated in BC tissues. Importantly, we found that a higher level of RBM24 was correlated with poor prognosis in BC patients. Overexpression of RBM24 promoted BC cell proliferation, while depletion of RBM24 inhibited BC cell proliferation in vivo and in vitro. Mechanistically, RBM24 positively regulated Runx1t1 expression in BC cells by binding to and enhancing Runx1t1 mRNA stability. Furthermore, Runx1t1 in turn promoted RBM24 expression by interacting with the transcription factor TCF4 and suppressing the transcription of miR-625-5p, which directly targets RBM24 and suppresses RBM24 expression. RBM24-regulated BC cell proliferation was moderated via the Runx1t1/TCF4/miR-625-5p feedback loop. These results indicate that the RBM24/Runx1t1/TCF4/miR-625-5p positive feedback loop participates in BC progression. Disruption of this pathway may be a potential therapeutic strategy for BC treatment.

      • KCI등재

        The Phytotoxic Effects of Selenium–Mercury Interactions on Root Growth in Brassica rapa (LvLing)

        Zhi-Wei Bian,Jian Chen,Hui Li,Dan-Dan Liu,Li-Fei Yang,Yue-Lin Zhu,Wen-Li Zhu,Wei Liu,Zheng-Zheng Ying 한국원예학회 2016 Horticulture, Environment, and Biotechnology Vol.57 No.3

        Rapid industrial and agricultural development has dramatically increased the emission of selenium (Se) and mercury (Hg) into the environment. Combined soil pollution by Se and Hg poses a potential threat to crop production. However, no toxic effects of Hg–Se interactions on plants have been reported previously. In this study, we investigated the effects of Hg–Se interactions on biochemical and physiological indices in the roots of Brassica rapa (LvLing). Seedlings were treated hydroponically with solutions of mercury chloride (1 μM), sodium selenite (4 μM), or a combination of the two. Combined Hg+Se treatment significantly inhibited root growth, reduced root biomass, and enhanced reactive oxygen species (ROS) and malondialdehyde accumulation and led to a loss of plasma membrane integrity. The combined treatment increased glutathione peroxidase, glutathione S-transferase, and peroxidase activity, reduced superoxide dismutase activity, and had no effect on catalase activity. In addition, we detected increased glutathione concentrations in root tips and reduced ascorbic acid concentrations in the presence of Hg+Se relative to individual treatments with these elements. Thus, Hg–Se interactions enhanced oxidative injury, cell death, and phytotoxicity in B. rapa roots.

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