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      • KCI등재

        Effect of O2 Plasma Treatment on Density-of-States in a-IGZO Thin Film Transistors

        Xing-Wei Ding,Fei Huang,Sheng Li,Jianhua Zhang,Xue-Yin Jiang,Zhi-Lin Zhang 대한금속·재료학회 2017 ELECTRONIC MATERIALS LETTERS Vol.13 No.1

        This work reports an efficient route for enhancing the performanceof amorphous InGaZnO (a-IGZO) thin film transistors (TFT). Themobility was greatly improved by about 38% by means of O2plasma treatment. Temperature-stress was carried out to investigatethe stability and extract the parameters related to activation energy(Ea) and density-of-states (DOS). The DOS was calculated on thebasis of the experimentally obtained Ea, which can explain theexperimental observation. A lower activation energy (Ea, ~0.72 eV)and a smaller DOS were obtained in the O2 plasma treatment TFTbased on the temperature-dependent transfer curves. The resultsshowed that temperature stability and electrical propertiesenhancements in a-IGZO thin film transistors were attributed to thesmaller DOS.

      • Dynamic Profiles of Ubiquitination and Autophagy Associated with Paternal Mitochondria Degradation during Mouse Postfertilization Development

        Xing-Wei Liang,Yong-Xun Jin,Ga-Young An,Seul-Ki Lee,Jung-Woo Kwon,Xiang-Shun Cui,Nam-Hyung Kim 한국동물번식학회 2012 Reproductive & Developmental Biology(Supplement) Vol.36 No.2s

        It is well established that mitochondrial genome is strictly maternally inherited in mammalian, despite the fact that paternal mitochondria enter into oocyte during fertilization. To date, although some mechanisms have been extrapolated to interpret the elimination of paternal mitochondria, the exact mechanism still is unclear. Recent studies suggest that autophagy process and the ubiquitin-mediated degradation pathway may be involved in elimination of paternal mitochondria. However, the dynamic profiles of autophagy and ubiquitination associated with paternal mitochondria degradation have not been determined in mouse model. Through immunostaining with specific antibody LC3 and Ubiquitin and confocal microscopy, we investigated the dynamic profiles of LC3 and Ubiquitin signals in mouse embryos during preimplantation development. In addition, embryos were stained with MitoTracker Red for tracking the degradation process of paternal mitochondria. Our results showed that paternal mitochondria gradually degraded during postfertilization development, and sporadic paternal mitochondria were found at least in 16 cell embryos. LC3 and Ubiquitin signals appeared in the midpiece of sperm at 3 h postfertilization, and they were strictly colocalizated with paternal mitochondria from zygote to 2 cell embryo. Nevertheless, the colocalization became loose at 4 cell embryos, and gradually disappeared beyond 4 cell embryos. Our results confirmed that autophagy process and the ubiquitin-mediated degradation pathway may take part in the postfertilization remove of paternal mitochondria.

      • SCISCIESCOPUS

        Recovery of metals from chloride leach solutions of anode slimes by solvent extraction. Part I: Recovery of gold with Cyanex 272

        Xing, Wei Dong,Lee, Man Seung,Senanayake, Gamini Elsevier 2018 Hydrometallurgy Vol.180 No.-

        <P><B>Abstract</B></P> <P>A separation process was developed to recover Au(III) from the chloride leach solution of anode slime using selective extraction and stripping step. The anode slime contained Ag, Au, Cu, Ni, Sn and Zn. The extraction with Cyanex 272 in kerosene was conducted by varying the HCl concentration of the solution from 0.5 to 9 M. Most of Au(III) and Sn(II) were extracted into Cyanex 272/kerosene phase together with a small amount of Cu(II) and Zn(II). The Au(III) in the loaded Cyanex 272 was selectively stripped over Sn(II) by (NH<SUB>4</SUB>)<SUB>2</SUB>S<SUB>2</SUB>O<SUB>3</SUB>. The McCabe-Thiele diagrams for the extraction and stripping were constructed. Extra pure Au(III) solution was recovered from the leach liquor by batch simulation experiments of two stage countercurrent extraction with Cyanex 272 and by one stage stripping with (NH<SUB>4</SUB>)<SUB>2</SUB>S<SUB>2</SUB>O<SUB>3</SUB>. The developed process can be applied to recover gold from a hydrochloric acid solution containing Ag(I), Cu(II), Sn(II) and Zn(II).</P> <P><B>Highlights</B></P> <P> <UL> <LI> A process was developed to recover Au(III) from anode slime leaching solution. </LI> <LI> HCl concentration was varied from 0.5 to 9 M to investigate the separation behavior. </LI> <LI> Cyanex 272 selectively extracted Au(III) and Sn(II) over Cu(II), Zn(II), Ni(II) and Ag(I). </LI> <LI> Only Au(III) in the loaded Cyanex 272 was stripped by (NH<SUB>4</SUB>)<SUB>2</SUB>S<SUB>2</SUB>O<SUB>3</SUB>. </LI> <LI> The purity of Au(III) in stripping solution was higher than 99.9%. </LI> </UL> </P>

      • SCOPUSKCI등재

        Tumor Promoting Function of DUSP10 in Non-Small Cell Lung Cancer Is Associated With Tumor-Promoting Cytokines

        Xing Wei,Chin Wen Png,Madhushanee Weerasooriya,Heng Li,Chenchen Zhu,Guiping Chen,Chuan Xu,Yongliang Zhang,Xiaohong Xu 대한면역학회 2023 Immune Network Vol.23 No.4

        Lung cancer, particularly non-small cell lung cancer (NSCLC) which contributes more than 80% to totally lung cancer cases, remains the leading cause of cancer death and the 5-year survival is less than 20%. Continuous understanding on the mechanisms underlying the pathogenesis of this disease and identification of biomarkers for therapeutic application and response to treatment will help to improve patient survival. Here we found that a molecule known as DUSP10 (also known as MAPK phosphatase 5) is oncogenic in NSCLC. Overexpression of DUSP10 in NSCLC cells resulted in reduced activation of ERK and JNK, but increased activation of p38, which was associated with increased cellular growth and migration. When inoculated in immunodeficient mice, the DUSP10-overexpression NSCLC cells formed larger tumors compared to control cells. The increased growth of DUSP10- overexpression NSCLC cells was associated with increased expression of tumor-promoting cytokines including IL-6 and TGFβ. Importantly, higher DUSP10 expression was associated with poorer prognosis of NSCLC patients. Therefore, DUSP10 could severe as a biomarker for NSCLC prognosis and could be a target for development of therapeutic method for lung cancer treatment.

      • KCI등재

        Experiment Study on Fatigue Performance of Perforated Shear Connectors

        Xing Wei,Lin Xiao,Shiling Pei 한국강구조학회 2017 International Journal of Steel Structures Vol.17 No.3

        In order to investigate the fatigue behavior of perforated shear connection in steel-concrete composite bridges, 24 connection specimens with different geometric configurations were subjected to static and fatigue testing protocols. Using the design shear resistance of perforated shear connectors obtained from static push-out tests as a reference load level, numbers of fatigue cycles under different cyclic load levels were determined. Accumulated relative slip between steel and concrete components was used to characterize and track fatigue damage accumulation. The relationship between cycle numbers and accumulated relative slip between steel and concrete was established. Test results revealed that the fatigue damage of perforated shear connectors can be divided into three stages, and fatigue life of perforated shear connectors can be evaluated by the accumulated slip, which depends on the maximum shear stress and stress range.

      • KCI등재

        Chemical, optical, and electrical characterization of Ga2O3 thin films grown by plasma-enhanced atomic layer deposition

        Xing Li,Hong-Liang Lu,Hong-Ping Ma,Jian-Guo Yang,Jin-Xin Chen,Wei Huang,Qixin Guo,Jijun Feng,David Wei Zhang 한국물리학회 2019 Current Applied Physics Vol.19 No.2

        Thin Ga2O3 films were grown on Si (100) using trimethylgallium (TMG) and oxygen as the precursors through plasma-enhanced atomic layer deposition. The depositions were made over a temperature range of 80–250 °C with a growth per cycle of around 0.07 nm/cycle. Surface self-saturating growth was obtained with TMG pulse time ≥20 ms at a temperature of 150 °C. The root mean square surface roughness of the obtained Ga2O3 films increased from 0.1 nm to 0.3 nm with increasing the growth temperature. Moreover, the x-ray photoelectron spectroscopy analysis indicated that the obtained film was Ga-rich with the chemical oxidation states Ga3+ and Ga1+, and no carbon contamination was detected in the films after Ar+ sputtering. The electron density of films measured by x-ray reflectivity varied with the growth temperature, increasing from 4.72 to 5.80 g/cm3 . The transmittance of Ga2O3 film deposited on a quartz substrate was obtained through ultraviolet visible (UV–Vis) spectroscopy. An obvious absorption in the deep UV region was demonstrated with a wide band gap of 4.6–4.8 eV. The spectroscopic ellipsometry analysis indicated that the average refractive index of the Ga2O3 film was 1.91 at 632.8 nm and increased with the growth temperature due to the dense structure of the films. Finally, the I-V and C-V characteristics proved that the Ga2O3 films prepared in this work had a low leakage current of 7.2 × 10−11 A/cm2 at 1.0 MV/cm and a high permittivity of 11.9, suitable to be gate dielectric.

      • KCI등재

        Theoretical Analysis on Molecular Magnetic Properties of N-Confused Porphyrins and Its Derivatives

        Wei, Wei,Bai, Fu-Quan,Xia, Bao-Hui,Zhang, Hong-Xing Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.9

        We have theoretically investigated the magnetic properties of N-confused porphyrin (NCP), tetraphenyl-N-confused porphyrin (TPNCP) and their substituted derivatives with O, S and Se heteroatoms (2ONCP, 2STPNCP, 2SeNCP, 2OTPNCP, etc.) by using DFT method. In the minimum energy structures of the 2OTPNCP, the two couples opposite phenyl substitutes are staggered. In the case of TPNCP, 2STPNCP and 2SeTPNCP, two phenyls being respectively close to or opposite to N-confused pyrrole are found to be pointed the same direction, whilst others are in the opposite direction. Based on the equilibrium structures, the $^1H$ chemical shifts and nucleus-independent chemical shifts (NICS) are calculated in this paper. The ${\pi}$ current density being induced by the tridimensional perpendicular magnetic field transmits the inner section of the pyrrole segments for NCP and TPNCP. As for their substituted derivatives with O, S and Se atoms, the current path passes through the outer section of the two heterorings. The NICS values at the ring critical points of the heterorings are much lower (in absolute value) than those of which is at the center of an isolated pyrrole molecule. The $^1H$ NMR for ${\beta}H$ atoms of the heterorings decreases from O, S to with Se.

      • Recovery of metals from chloride leach solutions of anode slimes by solvent extraction. Part II: Recovery of silver and copper with LIX 63 and Alamine 336

        Xing, Wei Dong,Lee, Man Seung,Senanayake, Gamini Elsevier 2018 Hydrometallurgy Vol.180 No.-

        <P><B>Abstract</B></P> <P>In Part 1 of this paper, gold(III) and Sn(II) were recovered from the chloride leach solution of anode slimes by extraction with Cyanex 272 and stripping with (NH<SUB>4</SUB>)<SUB>2</SUB>S<SUB>2</SUB>O<SUB>3</SUB> and NaOH solutions for gold(III) and Sn(II), sequentially. In this work, solvent extraction experiments were conducted to recover Ag(I) and Cu(II) from the Au(III) free raffinate containing Ni(II), Sn(II) and Zn(II) using two systems. In the first system, Cu(II) and Ag(I) were sequentially separated using LIX 63 and Alamine 336, respectively. Dilute HCl and NH<SUB>4</SUB>SCN were used as the stripping agents for Cu(II) and Ag(I), respectively. In the second system, Cyanex 301 co-extracted Ag(I), Cu(II) and Sn(II) from the Au(III) free raffinate. Aqua regia at different dilutions stripped these three metal ions from the loaded Cyanex 301. First, Cu(II) was selectively stripped from the loaded Cyanex 301 by employing ten times diluted aqua regia. Second, most of Ag(I) was selectively stripped over Sn(II) by five times diluted aqua regia. A process flowsheet for the separation and recovery of noble and base metals from the chloride leach solution of anode slime using extraction and stripping has been proposed.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Au(III), Ag(I) and Cu(II) were recovered from the leach liquor of anode slime. </LI> <LI> Gold(III) was first separated by selective extraction with Cyanex 272. </LI> <LI> Cu(II) was then recovered by extraction with by LIX 63 and stripping with HCl solution. </LI> <LI> Extraction with Alamine 336 followed by stripping with NH<SUB>4</SUB>SCN led to Ag(I) solution. </LI> <LI> Both Cu(II) and Ag(I) was simultaneously extracted by Cyanex 301. </LI> </UL> </P>

      • Separation of gold(III) from hydrochloric acid solution containing platinum(IV) and palladium(II) by solvent extraction with Cyanex 272 and LIX 63

        Xing, Wei Dong,Lee, Man Seung,Kim, Young Hwan Elsevier 2018 Journal of industrial and engineering chemistry Vol.59 No.-

        <P><B>Abstract</B></P> <P>Solvent extraction experiments were performed to separate Au(III), Pt(IV) and Pd(II) in the HCl concentration ranged from 0.5 to 9M. Cyanex 272 extracted only Au(III) among the three metals, while both Au(III) and Pd(II) was extracted by LIX 63 in the experimental ranges. The Au(III) in the loaded Cyanex 272 and LIX63 was stripped by either (NH<SUB>4</SUB>)<SUB>2</SUB>S<SUB>2</SUB>O<SUB>3</SUB> or (NH<SUB>2</SUB>)<SUB>2</SUB>CS. The concentration ratio of Au(III) to Pd(II) affected the extraction behavior of Au(III) and Pd(II) by LIX 63. The characteristic vibration bands of Cyanex 272 and LIX 63 were proposed by analyzing the FT-IR.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Solvent extraction experiments were done to separate Au(III), Pt(IV) and Pd(II). </LI> <LI> HCl concentration was varied from 0.5 to 9M to investigate the separation behavior. </LI> <LI> Cyanex 272 extracted only Au(III), leaving Pt(IV) and Pd(II) in the raffinate. </LI> <LI> LIX 63 extracted both Pd(II) and Au(III), leaving Pt(IV) in the raffinate. </LI> <LI> The Au(III) in the loaded Cyanex 272 and LIX63 was stripped by (NH<SUB>4</SUB>)<SUB>2</SUB>S<SUB>2</SUB>O<SUB>3</SUB> and (NH<SUB>2</SUB>)<SUB>2</SUB>CS. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Effect of HCl concentration on the extraction percentage of metals. Experimental conditions: (a) [Cyanex 272]=0.2M, (b) [LIX 63]=0.2M; [Au]=[Pd]=[Pt]=100mgL<SUP>−1</SUP>, shaking time, 30min; O/A=1.</P> <P>[DISPLAY OMISSION]</P>

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