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      • KCI등재

        Preparation and photocatalytic activity of a novel BiOCl/g‑C3N4 thin film prepared via spin coating

        Wei‑Qin Cai,De‑Fang Zhang,Feng‑Jun Zhang,Won‑Chun Oh 한국세라믹학회 2020 한국세라믹학회지 Vol.57 No.3

        Novel BiOCl/g-C3N4 thin film photocatalysts were synthesized via a simple two-step spin coating method. The prepared photocatalysts were characterized by X-ray diffraction, scanning electron microscopy, and ultraviolet–visible spectroscopy. The photocatalytic activity of the thin films for the degradation of rhodamine B under visible light (λ ≥ 400 nm) was investigated. The results showed that the BiOCl/g-C3N4 thin film photocatalysts exhibited significantly improved visible light absorption compared to the pure BiOCl thin film. The BiOCl/g-C3N4 film showed a rhodamine B degradation efficiency of 81.0% under visible light, which is 23.8 times higher than that of the pure BiOCl thin film. This excellent photocatalytic activity of the BiOCl/g-C3N4 film can be attributed to its efficient electron–hole separation due to the presence of g-C3N4.

      • KCI등재

        이옹의 生涯와 思想

        張德偉 한국철학사연구회 2003 한국 철학논집 Vol.13 No.-

        이옹은 학술사상과 인품과 인격이 孫奇逢, 黃宗羲와 더불어 明末·淸初의 三大 儒者이다. 그러나 오랜 기간, 이옹에 대한 연구는 극히 미비하였을 뿐만 아니라 다소의 그릇된 견해로 말미암아 학술사상사에 있어서의 이러한 三大儒란 지위와 칭호에 상응하는 연구가 이루어지지 못하였다. 이옹의 철학은 ‘尊德性’에 대한 강조를 입론의 근본으로 삼음으로써 기본적으로는 심학의 입장을 취하였으나, ‘道問學’에 대하여도 이를 도외시하지 않음으로써 양명학의 末流적인 空疏하고 無用한 점에 대한 반성의 입장을 취하였다. 그는 ‘反身實踐’을 중시하고 ‘悔過自新’을 강조함으로써 유학이 體와 用을 모두 갖춘 ‘大人之學’임을 宣揚하였다. 그러므로 이옹의 철학은 ‘全體大用’이 특색이라고 할 수 있다. 그의 사상은 程朱學으로부터 陸王學으로 전환되는 경향을 보이고는 있지만, 門戶의 격파를 주장함으로써 정주육왕을 종합하여 孔孟의 宗旨를 잇고자 하였다. 본 논문은 그의 사상발전과정과 원인 및 의의에 대하여 연구하였고, 특히 ‘明體’와 ‘明體工夫’에 대하여 중점적으로 연구하였다. 이러한 연구는 淸初 유학사상의 발전과 동향을 이해하는 데 도움을 줄뿐만 아니라 ‘天崩地解’라는 대 변혁기에 있어서 진정한 어느 한 유학자의 고뇌와 갈등을 이해할 수 있게 할 것이다. For a long time, the study on Li Yong, a thinker who was considered as one of the three great Confucian in the late Ming Dynasty and early Ching Dynasty for his thinking and personality, has been rather weak. This is not a reasonable condition. Li Yong emphasizes preserving ones moral nature(尊德性), so he stands for Lu-Wang school. At this time, in order to correct the malpractice of later offshoot of Wang Yang-Ming school, he also emphasizes intellectual inquiry(道問學). He attaches importance to practice in person, correct ones own mistakes and get original substance back. He preaches that Confucianism is a theory of Great-Man(大人) including original substance(體) activity(用). The whole original substance and the great use(全體大用) is characteristic of the philosophic theory of Li Yong. There has a turn in the developing of his thinking from Cheng-Chu school to Lu-Wang school, in the run, however, he breaks the boundary between Cheng-Chu school and Lu-Wang school, integrates all these person and comes back to Confucius and Mencius. We study the trace, reason and signification of the change of his thinking, but we lay more emphasis on his thinking about original substance(明體) and the effort to furbish original substance(明體工夫), that is to say, three chapters respectively. We think this dissertation will help understand the new trend of Confucianism in the late Ming Dynasty and early Ching Dynasty, and observe in near distance the impact on the spirit of a true Confucian when his society has a tremendous change to the moment. 李옹以其學術思想及人格力量與黃宗羲·孫奇逢合稱爲明淸之際三大儒, 然而, 長期以來, 對他的硏究不僅嚴重不足, 而且存在諸多誤解, 這是與其他位不相稱的. 李옹哲學强調“尊德性” 以立本, 不離心學立場, 又兼采“道問學” 而對王學末流的空疏無用作出了反省. 他重視反身實踐, 强調悔過自新, 宣揚儒學是體用皆備的“大人之學”, 故其哲學以“全體大用” 爲特色. 他的思想有一個由程朱而陸王的轉向, 但又主張破門戶之見, 合程朱陸王而歸宗孔孟. 本文旣硏究他的思想發展過程·原因及意義, 更各以三章篇幅重点硏究了他的“明體” 及“明體工夫” 思想. 這些硏究, 將有助于理解淸初儒學思想發展的動向, 也有助于理解如此“天崩地解”的大變局對一個眞正儒家學者在心靈上的影響.

      • KCI등재
      • C-66 : Histone H1-derived Antimicrobial Peptides from Carassius auratus

        ( Wei Quan De ),차형준 한국화학공학회 2007 화학공학의이론과응용 Vol.10 No.2

        Among 3 obtained-PCR products, we identified a novel histone H1 coding sequence of 576 Bp which belongs to histone H1 family and revealed it has 78% homologous with amino acid sequence of histone H1 from Salmon salar, which had been demonstrated that it plays an important role in salmon defenses against infectious pathogens. The H1 histone of goldfish contained several predicting cleavage sites. We successfully expressed the products of whole CDs (No ATG) of H1 histone and its N-terminal part(2-38aa) in Pichia pPIC9K expression system. The products of H1 histone and its N-terminal deriving peptide (AEVAPAASAPPAKAPKKKSAAKAKKAGPAVGDLIVKA) show antimicrobial activity H1 histone and the fragment in this paper are novel antimicrobial peptides found in goldfish. Pichia secretion expression system is a good way for expression of mature antimicrobial peptides. H1 histone plays an important role in innate immune responses of goldfish. The antimicrobial activity of the fragments of the H1 histone cleaved by Arg-c, Asp-N and Glutatmyl endopeptidases will be further studied.

      • KCI등재

        Seismic Performance of a Full-Scale Precast Concrete L-Shaped Column Frame Structure with a Grouted Connection

        Wei-Bin Ni,De-Hao Qiao,Hong-Wei Sun,Xu Zhang,Zhong-Wen Zhang,Shao-Jie Wang 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.2

        Precast concrete frame structure with nonrectangular columns are becoming attractive to researchers and engineers owing to advantages such as avoiding column protrusion from walls and saving space. This paper presents the experimental investigation of a full-scale precast concrete frame structure with L-shaped columns (PCFS) subjected to reverse cyclic loading. The precast connection adopted grouted anchor connection. As a comparison and benchmark, one full-scale monolithic sample (RCFS) was also tested. The results indicates that the greater steel ratio in the grouted anchor connection region leads to a high local stiffness of the elements, which contributed to delaying occurrence of the first crack at the grouting holes. The failure mode, lateral load capacity, stiffness degradation, load-carrying capacity degradation, energy-dissipating capacity, ductility and interlayer residual deformation were compared between two specimens. PCFS specimen exhibited comparatively better hysteretic behavior, energy-dissipating capacity, residual deformation-resisting capacity and ductility. For RCFS and PCFS specimens, the peak load difference was within 7%. About 15% increases in ductility were observed for PCFS specimen compared with RCFS specimen. The test results would provide reference for the application of the precast concrete structure with nonrectangular columns in the new residential buildings.

      • KCI등재

        An Exploratory Study on the Influence of the Fairness of the Performance Measurement System and Business Reform Force on the Business Performance :

        Wang, De Wei(왕덕위),Kim, Won Bae(김원배) 글로벌경영학회 2018 글로벌경영학회지 Vol.15 No.4

        From the view of the development levels in global manufacturing industry, the United States and China are typical representatives of developed countries and developing countries respectively. Although the research on enterprises is mature in advanced countries, it is still to be verified whether the research results in advanced countries are applicable to developing countries. Especially under the increasingly fierce competition environment, whether Chinese manufacturing enterprises should learn from advanced ideas of foreign countries to carry out management innovations and how to carry it still remain the subject of research. Based on previous research results, this research aims to observe the impact resulted from the changing management elements and justice from the achievement measurement system for the Chinese manufacturing enterprises in the process of management reform.The findings confirm the positive and effective impacts of changes in management elements on the business performance and show that the fairness of the performance measurement system plays a mediating role between the business innovation efforts and business performance. It can be concluded that the elements of change management in enterprises of capitalist countries also led a significant contribution to the success of business management innovation in enterprises of socialist countries through empirical analysis. In addition, the fairness of the performance measurement system in the process of business innovation is more important than anything else. 브루킹스 연구소에 나온 통계 결과를 보면 세계 제조업 부가가치 순위 1위는 중국이고 2위는 미국이다. 선진국에서는 기업경영혁신에 대한 연구가 많이 이루어지고 있다. 하지만 선진국의 연구 결과가 후진국의 기업에 적용할 수 있는가에 대해서는 아직 명확하게 밝혀진 바가 거의 없다. 특히 점점 치열한 경쟁 환경 속에서 중국 제조 기업이 외국의 선진 경영혁신 방법을 참고하여 경영혁신을 실시해도 되는지 그리고 어떻게 혁신할 건지 등 연구문제는 아직 남아있다. 본 연구는 선행연구 결과를 토대로 중국제조 기업대상으로 경영혁신과정에서 선진국의 혁신변화관리요소와 성과측정시스템의 공정성이 경영성과에 미치는 영향을 보고자 하였다. 실증분석을 위해 중국 제조 기업을 대상으로 설문한 149개의 표본을 사용하여 요인의 상관관계분석과 경로분석을 통해 선진국 경영혁신 성공요인들이 중국의 경영혁신과정에서 똑같은 긍정적 효과 주고 있다는 사실을 검증하고 자 하였다. 연구결과 성과측정시스템의 공정성은 경영혁신과 경영성과 간에 매개 효과가 있다는 사실이 밝혀졌다. 중국 제조기업 경영혁신과정에서 성과측정시스템의 공정성은 비재무성과한테 직접영향을 미치고 있고, 재무성과에게는 직접적인 영향은 없으나, 비재무성과를 통해 재무성과에게 간접영향을 미치고 있다. 그리하여 본 연구를 통해 선진국 기업혁신 성공 요인들이 중국제조기업의 혁신과정에서도 경영성과(재무、비재무)한테 긍정적인 영향을 미치고 있다는 사실을 알 수 있었으며, 중국 제조 기업이 혁신과정에서 공정한 성과측정시스템을 사용하면 더 좋은 경영성과를 낼 수 있을 것이다.

      • Analysis of Indoleamine 2-3 Dioxygenase (IDO) and EGFR Co-expression in Breast Cancer Tissue by Immunohistochemistry

        Bi, Wei-Wei,Zhang, Wei-Hua,Yin, Gui-Hua,Luo, Hong,Wang, Shou-Qin,Wang, Hongran,Li, Chao,Yan, Wei-Qun,Nie, De-Zhi Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.14

        Background: To determine the amount of co-expression of IDO and EGFR in breast cancer patients. Materials and Methods:In order to obtain the distribution of co-expression of IDO and EGFR in breast cancer, we tested 110 breast cancer paraffin tissue blocks with immunohistochemical methods. Then we investigated the relationship between the diagnostic and pathologic characteristics (tumor size, lymph node status, histologic grade, the gene expression of ER, PR, HER2, p53, Ki67 and PCNA) with the situation of co-expression of IDO and EGFR by reviewing the medical records of 32 breast cancer patients. Results: Among 110 breast cancers, 32 cases demonstrated IDO and EGFR co-expression (29.1%), IDO and EGFR synchronous co-expression being found in 19.1% and asynchronous in 10.0%. Conclusions: IDO and EGFR were co-expressed in breast cancer, including synchronous and asynchronous co-expression. The results suggest that considering IDO and EGFR as two indicators for breast cancer treatment or prognosis analysis provides a potential option of individual treatment for the portion of breast cancer patients with co-expression of IDO and EGFR.

      • Prognostic Values of Various Clinical Factors and Genetic Subtypes for Diffuse Large B-cell lymphoma Patients: A Retrospective Analysis of 227 Cases

        Zhou, De,Xie, Wan-Zhuo,Hu, Ke-Yue,Huang, Wei-Jia,Wei, Guo-Qing,He, Jing-Song,Shi, Ji-Min,Luo, Yi,Li, Li,Zhu, Jing-Jing,Zhang, Jie,Lin, Mao-Fang,Ye, Xiu-Jin,Cai, Zhen,Huang, He Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

        Aim: To analyze the significance of different clinical factors for prognostic prediction in diffuse large B-cell lymphoma (DLBCL) patients. Methods: Two hundred and twenty-seven DLBCL patients were retrospectively reviewed. Patients were managed with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) regimen or rituximab plus the CHOP (RCHOP) regimen. Results: Lactate dehydrogenase (LDH), ${\beta}2$-microglobulin (${\beta}2$-M), B symptoms, Ann Arbor stage and genetic subtypes were statistically relevant in predicting the prognosis of the overall survival (OS). In the CHOP group, the OS in patients with germinal center B-cell-like (GCB)(76.2%) was significantly higher than that of the non-GCB group (51.9%, P=0.032). With RCHOP management, there was no statistical difference in OS between the GCB (88.4%) and non-GCB groups (81.9%, P=0.288). Conclusion: Elevated LDH and ${\beta}2$-M levels, positive B symptoms, Ann Arbor stage III/IV, and primary nodal lymphoma indicate an unfavorable prognosis of DLBCL patients. Patients with GCB-like DLBCL have a better prognosis than those with non-GCB when treated with the CHOP regimen. The RCHOP treatment with the addition of rituximab can improve the prognosis of patients with DLBCL.

      • KCI등재

        The Impact of Senior Mobility Funding on Hearing Aid Acquisition and Compliance to Hearing Aid Use in a Singapore Hospital

        Chua Wei De Kenneth 대한청각학회 2021 Journal of Audiology & Otology Vol.25 No.1

        Background and Objectives: In 2013, the Singapore government reviewed and expanded the Senior Mobility Fund (SMF) to provide subsidy for assistive devices, including hearing aids (HA). While SMF has improved accessibility to HA, its impact on HA acquisition has not been determined. The study aims to elucidate the influence of SMF on HA acquisition and the relationship between financial funding and compliance to HA use.Subjects and Methods: Retrospective review of 643 patients seen between January 2017 to January 2018 at the earnose and throat specialist outpatient clinic, who were referred for a hearing aid evaluation. Of the 643 patients, 109 patients with baseline hearing handicap (HH) scores recorded, and no formal diagnosis of cognitive impairment were included. The patients were grouped according to SMF eligibility and clinical data were obtained.Results: The odds ratio for acquiring HA was significantly higher with SMF, regardless of HH scores. When looking at actual degree of hearing loss (DHL), HA uptake was significantly higher in the least severe of DHL categories. There is no relationship between SMF and compliance to HA use. However, HH score is positively correlated with data log in regression analyses.Conclusions: SMF appears to influence HA acquisition. Especially in financially funded patients with low self-perceived HH, the benefits of HA may be underappreciated given the few hours of HA use. Further studies are warranted to investigate the impact of financial funding on outcomes of HA users to help policy planners and clinicians be prudent in the utilization of SMF.

      • RTN4 3'-UTR Insertion/Deletion Polymorphism and Susceptibility to Non-Small Cell Lung Cancer in Chinese Han Population

        Lu, De-Yi,Mao, Xu-Hua,Zhou, Ying-Hui,Yan, Xiao-Long,Wang, Wei-Ping,Zheng, Ya-Biao,Xiao, Juan-Juan,Zhang, Ping,Wang, Jian-Guo,Ashwani, Neetika,Ding, Wei-Liang,Jiang, Hua,Shang, Yan,Wang, Ming-Hua Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.13

        Nogo protein, encoded by gene reticulon-4 (RTN4), includes three major isoforms by different splicing, named Nogo-A Nogo-B and Nogo-C. Nogo proteins play an important role in the apoptosis of cells, especially in tumor cells. RTN4 single nucleotide polymorphisms (SNPs) can influence the efficiency of transcription and translation thus being related with an individual's predisposition to cancer. The CAA insertion/deletion polymorphism (rs34917480) within RTN4 3'-UTR has been reported to be associated with many cancer types. In order to investigate the relationship between this polymorphism and susceptibility to non-small cell lung cancer (NSCLC) in the Chinese population, we conducted the present case-control study including 411 NSCLC patients and 471 unrelated healthy controls. The genotype distributions were significantly different between cases and controls (p=0.014). We found that the del allele could significantly increase NSCLC risk (ins/ins vs ins/del: p=0.007, OR 1.46, 95%CI=1.11-1.93; dominant model: p=0.004, OR 1.47, 95%CI=1.13-1.92 and allele model: p=0.008, OR 1.35, 95%CI=1.08-1.67). This association was stronger in participants over 60 years old, males and smokers. We therefore conclude that the CAA insertion/deletion polymorphism (rs34917480) contributes to non-small cell lung cancer risk in Chinese population. Age, sex and environmental exposure are also related to carcinogenic effects of rs34917480.

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