[A Story by Lee Bong-gu] The Smell of Death

Lee Bong-gu,Chang Wang-rok(번역자) The Academy of Korean Studies 1968 Korea Journal Vol.8 No.1

흰쥐에서 염화비닐 폭로수준에 따른 소변내 thiodiglycolic acid 농도의 변화

왕승준,차봉석,노재훈,신동천,김명수,전근재 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.4

Objectives : It is the objective of this research to identify the variation of thiodiglycolic acid(TdGA) in urine with vinyl chloride monamer(VCM) exposure levels through methylation. Methods : After rats were exposed to vinyl chloride monomer of 4 levels, 0㎎/㎥, 50㎎/㎥, 150㎎/㎥, 500㎎/㎥, respectively, of which urine was sampled in each sampling time of 0 hour, 2 hours, 4 hours, 8 hours, 16 hours, 36 hours, 48 hours. After urine had been methylated with diazomethane in the preliminary experiment and the peak of 146 m/z had been verified, the main experiment was done. Results : In the variation of TdGA with sampling times, concentration of TdGA increased rapidly in 4 hours and then decreased after 8 hours. When the variation of urinary TdGA concentration in urine according to exposure level of VGM was verified through Kruskal-Wallis statistical method at each sampling time, the significant increment with the exposure levels at 2 hours, 4 hours, 8 hours after exposure was clarified. Conclusion : TdGA concentration in urine with increment of VCM exposure level increased, especially significantly at 2 hours, 4 hours, 8 hours of sampling time.

역사적 문화환경의 효율적 보존방안에 관한 건축계획적 연구(Ⅱ) : Focused on the laws for the preservation 보존을 위한 법률 검토와 보완을 중심으로

이왕기,이건호,이기승,최종후,최봉문 牧園大學校 建築·都市硏究센터 1996 建築·都市環境硏究 Vol.4 No.-

This paper is written as a specific part of a thesis, that is, A Study on the Architectual Planning for the Effective Preservation Program of the Historically Cultural Environment. In this paper, we deal with the preservation and development of the cultural assets, and preservation of the historically cultural environment, that is the most important problem in the modern society. First, we deal with the preservation of the cultural assets, and the related legal basis of the cultural assets. second, we deal with the problems of nomination of the cultural assets. Third, we review the laws related to the preservation of the cultural assets. Finally, we propose some suggestions for the complement of the related law.

역사적 문화환경의 효율적 보존방안에 관한 건축계획적 연구(Ⅰ)

최봉문,이건호,이기승,이왕기,최종후 牧園大學校 建築·都市硏究센터 1994 建築·都市環境硏究 Vol.2 No.-

There are two common problems that the mordern cities have. One is to how he citizens are effecially interested in the cultural remains in the cities. The other is to how the people who have the architectural treasure in the cities don't convert these into economical property values, but have a preserving awareness It is the tendency that the historical cultural environment is gradually incorporate into the area of the cities according to rapid increase in papulation and the diffuseness of the city. In this process some people think that the valuable historical architectural treasure is an obstacle in devising the city planning. This thesis is to how effecially preserve and applicate thet Taejon,s historical cultural environment. In this thesis it has made up questions to 1,134persons of Taejon citizents to what extent were rocognizing the local historical archtecural treasure. the questionnaires items were divided under five heads as follows. 1) the cognition about Taejon's historcal architectural treasure 2) The satisfaction to the preservation status 3) the opinion about the application plan The population characteristcs of effective answers were devided into sex, age, education level, occupation, occupation of architecture, duration of residence in Taejon, residential district, etc. The content of questionnaires were analyzed in chapter6 in detail. To preserve the historical cultural environment of cities is troublesome and complicated works right now, but it is our's duties and resposibilities to do necessaily. In this thesis (Ⅰ) it will be find the method to high up the recognition about the historical cultural environment on the basis of this recognition reserch and frame the architectural planning about the effective preservation and application plan.

흰쥐에서 니켈 및 카드뮴의 동시노출이 간에 미치는 영향

차봉석,왕승준,장세진 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.1

목적 : 이 연구는 적출간 관류법을 이용하여 영화니켈과 염화카드뮴의 동시 노출로 인하여 간에 나타나는 효과를 확인하는 데에 있다. 방법 : 간독성의 지표로서 AST, ALT, LDH의 농도 및 관류속도를 이용하였고 생존력에 대한 지표로서 산소소모율을 측정하였다. 300(±50) g의 흰쥐를 노출군(비노출군 및 50 μM/ 200 μM의 각 농도별 염화니켈과 염화카드뮴의 개별 투여군 및 동시 투여군)별로 5마리씩 총 35마리를 할당하였다. 간을 통과한 관류액을 채취하여 생화학적 간독성 지표를 측정했고 집단간의 시간의 경과에 따른 측정치의 비교를 위해 반복 측정된 2요인 분산분석을 실시하였다. 개별 투여군과 동시 투여군의 생화학적 지표간의 평균을 비교함으로써 상승효과에 대한 가능성을 확인했다. 결과 : 개별 투여군 및 동시 투여군 모두에서 AST, ALT, LDH가 증가했다. 관류속도 및 산소 소모율은 시간의 경과에 따라 감소했으나 통계적으로 유의한 차이를 보이지는 못했다. AST, ALT, LDH, 산소소모율이 일정 시간대 이후로 개별 노출군의 합보다 동시 노출군에서의 측정치가 더욱 크게 증가하였다. 결론 : 간독성에 대한 생화학적 지표의 변화를 확인함으로써 두 물질의 동시노출로 인한 복합적 효과는 상승효과일 가능성이 높은 것으로 보인다. Objectives : This research was intended to verify hepatic effect of simutaneously com-bined exposure of nickel chloride and cadmium chloride with IPRL (Isolated Perfumed Rat Liver) method. Methods : AST(aspartate aminotransferase), ALT(alanine aminotransferase), LDH (lac-tate dehydrogenase) and perfusion flow rate were used as the indicator of hepatotoxicity and oxygen consumption rate were used as the indicator of viability. 300(±50) g - weighted rats were allocated randomly to each group (control group, 50 μM·200 μM sera-rately exposure group of NiCl₂and CdCl₂, simultaneously combined exposure group of NiCl₂and CdCl₂by 5, totally 35. Buffer which got out of liver was sampled and then biochemical indicator of hepatotoxlcity was measured. In order to verify difference among groups, two way - repeated ANOVA was used. With comparing mean summation of sepa-rate exposure group with mean of simultaneous exposure group, possibility that combined effect could be synergistic effect was verified. Results : AST, ALT, LDH increased in both of separate exposure group and simultaneous exposure group. Perfusion flow rate and oxygen consumption rate decreased but statlstically significant difference among groups was not found. In each exposure group, AST, ALT, 7DH, oxygen consumption rate of simultaneous exposure group increased more than sum of separate exposure group after any sampling time. Conclusions : It was found that simultaneous combined effect could be synergistic effect through the biochemical indicator of hepatotoxicity.

정신분열병에 대한 Risperidone의 효과 및 안전성에 관하여

신석철,왕성근,지익성,이선우,이규광,이봉희,이진영,황선희,신용재,배경도,김정란 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

In order to evaluate the efficacy and safety of risperidone, 10 patients with chronic schizophrenia were examined for 8 weeks in a silgle-open study. After the wash-out period of 1 week, risperidone was administered. Efficacy was evaluated by means of Positive and Negative syndrome Scale for Schizophernia(PANSS) and Clinical Global Impression(CGI). Safety assessment included the Extrapyramidal Symptom Rating Scale(ESRS), vital signs, body weight, ECG, and laboratory tests. The results were as follows 1) On the PANSS total score, there was significant improvement of total score after 1 week (P<.05) of administratiom. 2) On the PANSS positive and negative subscal, there were significant improvement of posotive and negative scores after 2 weeks (P<.05) of administration. 3) On the PANSS general psychopatholgy subscals, there were significant improvement of general psychopathologyscores after 1 week (P<.05) of administratiom. 4) On the CGI, there was significant decreasement of clinical impression of severity of schizophrenia score after 2 week (P<.05) of administration. 5) A statistically significant increase in body weight (P<.05) was observed after 8 weeks of administration. 6) EPS reached the peak at the end of the 1st week of administration of risperidone (11.8± 24.25) but they were easily relieved by addition of benztropine and clonazepam. There was not significant change in laboratory tests, vital sign, ECG after 8 weeks of administration. These results suggest that Risperidone is an effective antipsychotics and clinically safe except for increased body weight in chronic schizophrenia.

측뇌실내 종괴의 감별진단 및 수술적 치료

김동규,김봉수,이상형,심기범,왕규창,정희원,김현집,조병규,최길수,한대희 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.2

We present a series of 42 patients with the lateral ventricular mass lesions who underwent operative removal between 1979 and 1992 at the Seoul National University Hospital. These lesions included 29 tumors, 10 benign cysts and 3 arteriovenous malformations. There were 20 lesions in the trigone, 14 in the frontal horn, 6 in the body, and 2 in the temporal horn. Together with the age of the patient, the location in the lateral ventricle and the CT or MR patterns, the range of the differential diagnosis of the lesions can be narrowed. The mass were removed by various surgical approaches ; 11 by the middle frontal gyrus, 10 by the superior parieto-occipital, 13 by the middle temporal gyrus, 4 by the anterior transcallosal, 2 by the posterior transcallosal and 3 by the combined approaches. The superior parieto-occipital approach left postoperative morbidities in 64% and other approaches in 20 to 25% of the cases. These morbidities included hemiparesis, hemianopsia, aphasia, memory distubance and seizure. Most hydrocephalus disappeared without the shunting procedure after removal of the lateral ventricular mass. The high frequency of postoperative complications in the superior parieto-occpital approach require meticulous consideration in the selection of this approach.

목원대학교 건축·도시공학부 발전방향에 관한 연구

이재연,최봉문,김도식,이왕기 牧園大學校 建築·都市硏究센터 1999 建築·都市環境硏究 Vol.7 No.-

School of Architecture and Urban Engineering, Mokwon University, was chosen the specialized school in Mokwon Univ. and has been receiving the National Strategic Financial Support(NSFS), by the Ministry of Education, Since 1997. This study was carried on for a part of NSFS programs. The objective of this study is to propose the new Educational Programs and development plannings for School of Architecture and Urban the Engineering for the specialized school in Mokwon University. This paper is the Summary of the whole study.

뇌사환자의 갑상선 기능, 전신대사 및 중증도에 관한 연구

이영주,정금희,왕희정,문봉기,한연희,이영석 아주대학교 의과학연구소 1999 아주의학 Vol.4 No.1

Background and Objectives : Brain death may lead to hormonal depletion, metabolic derangement and multiple organ dysfunction. We have carried out present study to examine the effects of brain death on the thyroid function, metabolic indices, and the severity scoring systems. Methods : 13 adults patients admitted for organ donation or brain death evaluation were examined after brain death was confirmed. Thyroid hormones measured were .thyroid stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), and free thyroxine (FT4). The metabolic indices measured were arterial ketone body ratio (AKBR), lactic acid (LA), and base defiat (BD). as for reference to the severity scoring systems, APACHE Ⅲ and multiple organ failure score (MOFS) were assessed on the day of brain death confirmation. Arterial blood was drawn for all measurements. Results : As for the thyroid function, there were significant decreases in T3 (40.48±20.96 ng/dL) and T4 (3.47±2.15 ㎍/dL), but no significant change in FT4 (0.75±0.31 ng/dL) and TSH (1.12±1.37 uIU/mL) compared to the normal range. Significant decreases in AKBR (0.39±0.31) and BD (-9.46±5.83 m㏖/L), and significant increase in LA (2.57±2.46 m㏖/L) In metabolic indices, were shown, as for severity scoring systems, APACHE Ⅲ score (101.54±19.41) and MOF score (9.11±2.57) indicated a high mortality. There were significant correlation between thyroid hormones (r=0.565 -0.781) but no correlation among other indices. Also, significant inverse correlations were shown between base deficit and lactic acid (r=-0.660), APACHE Ⅲ score (r=-0.726) and MOF score (r=-0.604). The highest correlation was observed between APACHE Ⅲ score and MOF score (r=0.851). Conclusions : As for the thyroid function, significant decrease in T3 and T4, and almost normal range of FT4 and TSH imply the euthyroid sick syndrome. Abnormal finding of the metabolic parameters indicates an inhibition of the aerobic metabolic rate of the body as a whole. And the severity scoring parameters are compatible with high mortality.

인터넷을 통한 연구센터 데이터베이스 시스템 구축

황의천,김일남,김남호,이봉형,왕수현 강원대학교 석재복합신소재제품연구센터 1997 석재연 논문집 Vol.2 No.-

본 연구의 목적은 석재복합 신소재제품 연구센터의 데이터베이스를 인터넷상에서 구축하여 이 데이터베이스가 연구활동 및 산업지원활동을 지원하도록 하는데 있다. 연구센터와 관련된 데이터베이스를 인터넷상의 세계정보망(world-wide web)이 연계 및 등록시켜 적극적으로 연구소의 활동을 홍보함과 동시에 세계정보망을 통한 각국의 다소 산업체의 산업정보를 실시간(real time)에 검색할 수 있는 정보망을 구축할 것이다. 석재복합 신소재제품 연구센터의 연구활동, 연구결과와 관련 산업체의 활동들을 데이터베이스화한 뒤, 이를 인터넷상에 제공함으로써 연구소의 연구활동 및 관련산업체들의 활동을 국제적으로 홍보하며 각국의 수요와 온라인으로 상담 및 전자우편을 나눌 수 있으므로 해서 지역경제의 국제화를 맞을 것으로 기대된다. 또한 앞으로 있을 정보고속도로의 구축과 활용을 위하여 본 연구는 기여하게 될 것이다. The purpose of this study is to construct the database of RRC research center on internet to support the research activities and industrial activities. Registering the database on internet, the center will proactively advertise the local industrial activities and will construct the information network which will enable the real-time search for industrial information. The database will include RRC's research activities, research output, and related industrial's activities. The homepage will advertise the RRC's activities worldwidely, support the online business, provide the e-mail, and it will enable the research center to be the leader of internationalization of local economy. The study will also contribute to further study of information highway.