본태성 혈소판 증다증 2예

주기산,임현성,김미자,양태영,허경,김완중,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

Essential thrombocythemia is a chronic myeloproliferative disorder of unknown origin, charcterized by excessive number of morphologically and functionally abnormal platelet in peripheral blood and abnormal proliferation of megakaryocytes in bone marrow. Its main clinical manifestations are hemorrhages and thromboses. The aim of therapy is suppression of the excessive bone marrow activity, which can be achieved by radioactive phosphorus, alkylating agent, hydroxyurea and interferon. Two cases were diagnosed at our hospital which had laboratory and clinical features compatible with this disease. We have successfully treated patient with hydroxyurea and platelet antiaggregating agent.

유색 보리 종실의 품종별 색소 특성

주완택,민경수,박노동 한국응용생명화학회 2003 Applied Biological Chemistry (Appl Biol Chem) Vol.46 No.4

유색보리 4품종과 보통보리 4품종 종실의 종피에 함유되어 있는 색소의 특성을 분석하여 해당작물의 신품종 육성시 우수계통 선발에 유용한 자료를 제공코자 하였다. 유색(검정)쌀보리인 Ab2231을 표준시료로 하여 실험한 결과 에탄올의 농도가 80%일 때 색소추출 효율이 양호하였다. 80% 에탄올에 1.0% 염산을 첨가한 것이 추출효율이 가장 좋았다. 추출시간에 따른 추출효율성을 조사한 결과 1시간 추출이면 충분하였다. 추출된 색소의 안정성을 유지하기 위하여 첨가시키는 산의 적정농도를 알아본 결과 1.0% HCl을 첨가한 농도에서 가장 낮은 색소량 감소율이 나타났다. 각 보리 품종 시료에서 추출한 색소의 흡광스펙트럼을 조사하였던 바, Ab2231의 그것은 535㎚에서 최대흡광파장을 나타내어 안토시아닌계 색소로 판단되었으며, 호계4호의 그것은 안토시아닌계 이외의 색소를 주로 함유하는 것으로 보였다. 한편, 추출된 색소의 특성에 따라 유색보리의 품종은 Ab2231와 모찌무기로 대표되는 쌀보리 그룹과 Lion과 호계4호로 대표되는 겉보리 그룹으로 분류되었다. The characteristics of the pigments extracted from grains of the colored barley varieties Ab2231. Mozzimugi, Lion, and Hogye 4 were studied. Extraction of the pigments from powder (80 mesh) of the barley grains was most efficient in 80% ethanol containing 1.0% HCI for 1 hr at 60℃. The pigments were also stable in 80% ethanol containing 1.0% HCI. Depending on the absorption spectra, maximal peak wavelength, and the ratio of A_(440)/Anu_(max), the varieties were separated into two groups, colored naked barley (Ab2231 and Mozzimugi) and colored covered barley (Lion and Hogye 4).

조혈모세포이식 후 발생한 주폐포자층 폐렴에 대한 고찰

주지현,최정현,이동건,백지연,고윤호,이혜정,김세희,신호진,박윤희,박지영,김유진,신완식,김춘추 대한감염학회 2001 감염 Vol.33 No.4

Background : Pneumocytitis cainii pneumonia (PCP) can occur in immunocompromised hosts especially such as AIDS or cancer patients. Although recent research had focused on PCP in AIDS patients, few studies have described the clinical presentations of PCP in recipients of stem cell transplantation (SCT). We evaluated the clinical manifestations of PCP in SCT patients admitted at St. Mary's hospital, Seoul, Korea. Methods : The medical records of 17 PCP patients undergoing SCT between Feb. 1998 and Feb. 2000 were reviewed. The diagnosis of PCP was confirmed through the demonstration of Pneumocytitis cainii via either cytology of brochoalveolar lavage (BAL) or histological technique of lung biopsy. CMV disease and CMV infection were confirmed by BAL culture and antigenemia respectively . Results : Seventeen patients were all recipients of allogeneic SCT and 7 of 17 patients were performed non-sibling SCT. Patients presented with symptoms including brief period (4 ∼23 days) of fever (76%), dyspnea (70%), cough (64%), and signs such as rare(58.8%), Sixteen patients (94%) had been receiving immunosuppressive agent such as cyclosporine A (64%) or Fk506 (35%) without PCP prophylaxis. Eleven patients (64%) were treated with corticosteroid with mean dose of 16 mg/day prednisolone and mean duration of 4.6 months after post-SCT period. Twelve patients were co-infected with CMV. Another co-infected miCroorganisms were Pseudomonas aeruginosa, Mycobacterium tuberculosis, herpes simplex virus, parainfluenza virus, Average duration of treatment with trimethoprim-sulfamethoxazole (TMP/SMX) was 21 ±9 days. Four patients died, and three of them were related with PCP. Conclusion : PCP developed frequently in patients who were taking immunosuppressive drug due to graft versus host disease or were not taking TMP/SMX prophylaxis. High risk patients showing fever, cough, or dyspnea should be considered to take early bronchoscopic intervention for detection of PCP. When treat for PCP, it also be considered to the possibility of coinfection such as CMV. (Korean J Infect Dis 33:273∼279, 2001)

Streptococcus mutans의 우식 활성에 미치는 Propolis의 효과

송완엽,백병주,주훈,김대범,송요한 大韓小兒齒科學會 1995 大韓小兒齒科學會誌 Vol.22 No.1

Propolis, a natural resinous product collected by honey bees, is known to exhibit various biological activities including anti-microbial, anti-inflammatory, and anti-tumor activities. The present study was designed to investigate the effects of ethanol extracted propolis(EEP) on the growth, glucosyltransferase(GTase) activity, and adherence to the saliva-coated hydroxyapatite(S-HA) beads of Streptococcus mutans JC-2(serotype c), S.mutans LMM-7(serotype e), and S. mutans OMZ-175(serotype f) in vitro. We found that the EEP had minimal inhibitory concentrations of 500-1000㎍/㎖ against S.mutans strains when these strains were cultured for 48 hours, and inhibited both water-insoluble and water-soluble glucan synthesizing GTase activities of S. mutans strains to the 93-100% at the concentration of 1600㎍/㎖, and also we found that the EEP inhibited the adherence of S. mutans strains to S-HA beads to the 76-96% at the concentrations of 200㎍/㎖. These results indicate that EEP has anti-cariogenic activity in vitro.

전국체육고등학교 투척선수들의 운동 상해에 관한 연구

배성완,강주혁,문주흠 목포대학교 스포츠산업 연구소 2006 스포츠 산업연구소 논문집 Vol.5 No.-

The purpose of this research is to work out the injury time, injury place, injury part, cause of injury, medical treatment, preventions against weight throwers at national physical education high schools and management and protection of them and advance of competence. As a result of questioning total 148 persons of shot putters (M20, F17), discus throwers(M21, F20), javelin throwers(M22, F20) and hammer throwers(M18, F10) who are registered at the Korean Amateur Athletic Federation, we come to the following conclusions. 1. As a result of comparison and analysis of the training programme where weight throwers were frequently injured by the event, the meaningful difference was obtained. Javelin throwers were injured most frequently while throwing training. 2. As a result of comparison and analysis of the meaningful difference of part which injury happened most frequently while throwers trained usually, the meaningful difference was obtained. Javelin throwers’ elbow injury was very frequent. 3. As a result of comparison and analysis of most frequently injured part by the event while weight throwing, the meaningful difference was obtained. Discus throwers’ waists were mostly injured while throwing. 4. As a result of comparison and analysis of frequently injured part by the event while weigh throwing training, the meaningful difference was obtained. Injury in waist part happened more frequently in rotary motion event than rectilineal motion event while weight throwing. 5. As a result of comparison and analysis of the event that throwers were injured frequently by sex while weight training, the meaningful difference was obtained. Women weight throwers were injured while jump squat training. 6. As a result of comparison and analysis of treatment period after injury by sex, the meaningful difference was obtained. It took women 4 weeks more to cure up and it was not short. 7. That difference that keep in mind method that can protect Shanghai when saw as exercise injury experience according to comparative analysis result by item appeared and rectilineal movement item selected most by method that mental power can protect Shanghai both item beam egg number It Eotda. 8. As a result of comparison and analysis of the season when thrower were injured frequently by experience, the meaningful difference was obtained. Throwers with below 1-4 year experience were injured frequently in summer. 9. As a result of comparison and analysis of the training time when weight throwers were injured frequently by result, the meaningful difference was obtained. Weight throwers who have never won the prize were injured frequently while training in the afternoon. 10. As a result of comparison and analysis of throwing motion when weight throwers were injured frequently by experience while throwing training, the meaningful difference was obtained. Throwers with below 1-4 year experience were injured frequently on waist twisting motion in the finish motion.

상호상관 함수를 이용한 지중선로 고장점 추정

朴星完,林泳範,鄭州桓,成洛煥,金喆煥,申明徹 成均館大學校 科學技術硏究所 1994 論文集 Vol.45 No.2

This paper is intended as an investigation of fault location for underground line. Over the past few decades a considerable number of studies have been made on protection of underground line. However, these approaches require the interruption of electric power supply from source for fault location estimation. Therefore, we proposed fault location algorithm for underground line protection without interruption of electric power supply. Cross correlation function is used in this algorithm. Also, EMTP data is used to demonstrate the capability of the proposed fault location algorithm.

STS 프로그램이 중학생들의 과학에 관련된 태도에 미치는 효과

정완호,김영신,권용주 한국교원대학교 과학교육연구소 1995 청람과학교육연구논총 Vol.5 No.1

The purpose of this study was to evaluate the effects of STS Programs on science-related attitude of junior high school students. For this study, samples of 198 students who are in grade 8 were selected. The eight STS Programs were used in this study. One group pretest-posttest design was used in this study as an experimental design. The TOSRA was used in this study as the science-related attitude evaluation instrument. The major results of this study are as followings: 1. The effects of STS programs about the junior high school students' science-related attitude indicated that there were no statistically significant differences between pretest and posttest. 2. Total students were classified as high(above about mean) or low (bellow about mean) on the basis of science-related attitude pretest scores. The low level students have improved from using of STS programs in teaching science on science-related attitude scores. The high level students have dropped from using of STS programs in teaching science on science-related attitude scores.

STS 교육운동의 국내 연구 경향 분석과 적용 방안에 관한 조사 연구

정완호,권용주,김영신 한국교원대학교 과학교육연구소 1993 청람과학교육연구논총 Vol.3 No.1

The purposes of this study are to analyse trend of STS movement in Korea and to collect basic data on application of STS to school science education. It investigated, from 1990 to March 1993, journals of 6 associations, a monthly magazine of science education, and printed materials of seminars or workshops about science education. It also surveied a question to 47 science teachers and 26 researchers who had experienced STS workshop. The results of the study are as follows: (1) The studies of STS increased since 1990, but they are made at a introduction or background of STS. (2) The 98.7% of the respondents want to apply STS in school science education. (3) They responded that a device for the application of STS which is added last part of each chapter or last chapter, will use the STS program that made by subject, still maintain current science curriculum. (4) They responded that the knowledge & compreshion domain and inquiry process domain contain more high than others. (5) The STS subjects for application to the school science education are as follows: Environment pollution, science for living, ethics of science, human health and disease, information communication, an ecosystem destruction, development and storage of natural resources. This study suggested that establishment of a research institute for systematic research of STS, in-service training, a new evaluation process, a balancing of other subjects and increasing learning hour and changing objectives.

다량의 하부위장관출혈이 병발된 Vibrio vulnificus 패혈증 1예

최주연,유진홍,한석원,이대훈,최민호,박순민,김연식,김선우,신완식,강문원,강성구 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.2

최근 저자들은 Vibrio vulnificus 감염에 의해 패혈증 및 이차성 피부 병변을 보인 42세의 남자 환자의 치료중 하부 위장관 출혈이 병발된 1예를 경험하였기에 보고하는 바이다. We experienced a case of Vibrop vulnificus septicemia which showed an unusual manifestation such as hematochezia. The patient was a 42-year-old man with chronic liver disease. The blood and wound culture revealed the organism. During intensive care, he suffered from massive hematochezi for several days. Colonoscopy and abdominal CT showed findings suspicious of ischemic colitis. To our knowledge, this is the first unusual case of V.vulnificus infection which showed massive lower gastrointestinal bleeding.

합리적 정서 처치기법이 심리적 요인에 미치는 효과

원주연,김병완,김윤태 대전대학교 기초과학연구소 2000 自然科學 Vol.11 No.2

이 연구는 여러 가지 심리적 요인에 긍정적 영향을 미칠 것으로 예상되는 합리적 처치기법(REBT)이 심리적 요인(경쟁불안 · 스포츠자신감 · 경쟁지향성)에 미치는 효과를 규명하여 사격 경기력 향상을 위한 심리적인 기초자료를 제공하는데 그 목적이 있다. 이에 본 연구는 3년 이상 선수경력이 있는 고등부 남 · 여 사격선수 80명을 대상으로 REBT 프로그램을 통해 종속변인의 변화량을 성별, 처치집단별로 이원변량분석을(two way ANOVA)을 실시하여 다음과 같은 결론을 얻었다. 1. 신체적 상태불안 변화량의 성별, 처치집단별 차이에서 처치집단이 통계적으로 유의한 차이가 나타났다. 즉, 처치집단이 통제집단에 비해 신체적 상태불안 수준이 큰 폭으로 감소하였다. 2. 인지적 상태불안 변화량의 성별, 처치집단별 차이에서 처치집단은 통계적으로 유의한 차이가 나타났다. 즉, 처치집단이 통제집단에 비해 인지적 상태불안의 감소가 현저했다. 3. 스포츠 자신감 변화량의 성별, 처치집단별 차이에서 처치집단은 통제집단에 비해 특성스포츠자신감과 상태스포츠자신감이 현격하게 증가하였다. 4. 과제지향성 변화량의 성별, 처치집단별 차이에서 처치집단은 통계적으로 유의한 차이가 나타났다. 즉 처치집단은 사후검사와 사전검사의 변화량이 감소하였다. 5. 자아지향성의 성별, 처치집단별 차이에서 모두 처치집단은 통제집단에 비해 자아지향성이 증가하는 경향이 있었다. 즉, 처치집단이 통제집단에 비해 자아지향성이 향상되는 결과이다. The present study is designed to examine the effect of REBT program on somatic anxiety, cognitive anxiety, sport confidence, task orientation and ego orientation. The object of the study is made up of eighty high school shooting players who all possess individual career record over three years. The collected data were analyzed by 2-Way ANOVA and the change of dependent variables was analyzed according to the gender groups and treatment groups. The implications of the study are as follows. 1. Change in somatic anxiety The gender and treatment groups showed effect on the change of somatic anxiety in the post and the pre-test 2. Change in cognitive anxiety The gender and treatment groups showed effect on the change of cognitive anxiety in the post and the pre-test 3. Change in sport-confidence The gender and treatment groups showed effect on the change of traiustate spork-confidence in the post and the pre-test 4. Change in task orientation The gender and treatment groups showed effect on the change of task orientation in the post and the pre-test 5. Change in ego orientation The gender and treatment groups showed effect on the change of ego orientation in the post and the pre-test