Extended use of Prostate Health Index and percentage of [-2]pro-prostate-specific antigen in Chinese men with prostate specific antigen 10–20 ng/mL and normal digital rectal examination

Peter Ka-Fung Chiu,Jeremy Yuen-Chun Teoh,Wai-Man Lee,Chi-Hang Yee,Eddie Shu-Yin Chan,See-Ming Hou,Chi-Fai Ng 대한비뇨의학회 2016 Investigative and Clinical Urology Vol.57 No.5

Purpose: We investigated the extended use of Prostate Health Index (PHI) and percentage of [-2]pro-prostate-specific antigen (%p2PSA) in Chinese men with prostate-specific antigen (PSA) 10–20 ng/mL and normal digital rectal examination (DRE). Materials and Methods: All consecutive Chinese men with PSA 10–20 ng/mL and normal DRE who agreed for transrectal ultrasound (TRUS)-guided 10-core prostate biopsy were recruited. Blood samples were taken immediately before TRUS-guided prostate biopsy. The performances of total PSA (tPSA), %free-to-total PSA (%fPSA), %p2PSA, and PHI were compared using logistic regression, receiver operating characteristic, and decision curve analyses (DCA). Results: From 2008 to 2015, 312 consecutive Chinese men were included. Among them, 53 out of 312 (17.0%) men were diagnosed to have prostate cancer on biopsy. The proportions of men with positive biopsies were 6.7% in PHI<35, 22.8% in PHI 35–55, and 54.5% in PHI>55 (chi-square test, p<0.001). The area under curves (AUC) of the base model including age, tPSA and status of initial/repeated biopsy was 0.64. Adding %p2PSA and PHI to the base model improved the AUC to 0.79 (p<0.001) and 0.78 (p<0.001), respectively, and provided net clinical benefit in DCA. The positive biopsy rates of Gleason 7 or above prostate cancers were 2.2% for PHI<35, 7.9% for PHI 35–55, and 36.4% for PHI>55 (chi-square test, p<0.001). By utilizing the PHI cutoff of 35 to men with PSA 10–20 ng/mL and normal DRE, 57.1% (178 of 312) biopsies could be avoided. Conclusions: Both PHI and %p2PSA performed well in predicting prostate cancer and high grade prostate cancer. The use of PHI and %p2PSA should be extended to Chinese men with PSA 10–20 ng/mL and normal DRE.

The Risk of Upper Urinary Tract Involvement in Patients With Ketamine-Associated Uropathy

Chi-Hang Yee,Jeremy Yuen-Chun Teoh,Pui-Tak Lai,Vivian Yee-Fong Leung,Winnie Chiu-Wing Chu,Wai-man Lee,Yuk-Him Tam,Chi-Fai Ng 대한배뇨장애요실금학회 2017 International Neurourology Journal Vol.21 No.2

Purpose: The aims of this study were to investigate the prevalence of upper tract involvement in ketamine-associated uropathy, and to determine the predictors of hydronephrosis in patients with a history of ketamine abuse. Methods: This was a cross-sectional study of a prospective cohort of patients with ketamine-associated uropathy. Data including demographics, pattern of ketamine abuse, pelvic pain and urgency or frequency (PUF) symptom score, uroflowmetry (UFM) parameters, serum renal function, and liver function tests were collected. Upon consultation, ultrasonography was performed to assess the function of the urinary system. Results: From December 2011 to October 2015, we treated 572 patients with ketamine-associated uropathy. Of these patients, 207 (36.2%) had managed to achieve abstinence at the time of their first consultation. Ninety-six patients (16.8%) in the cohort were found to have hydronephrosis on ultrasonography. Univariate analysis identified age, duration of ketamine abuse, PUF symptom score, voided volume on UFM, serum creatinine levels >100 μmol/L, and an abnormal serum liver enzyme profile as factors associated with hydronephrosis. Logistic regression revealed the following parameters to be statistically related to hydronephrosis: age (adjusted odds ratio [OR], 1.090; 95% confidence interval [CI], 1.020–1.166; P=0.012), functional bladder capacity (adjusted OR, 0.997; 95% CI, 0.995–0.999; P=0.029), serum creatinine >100 μmol/L (adjusted OR, 3.107; 95% CI, 1.238–7.794; P=0.016, and an abnormal serum liver enzyme profile (adjusted OR, 1.967; 95% CI, 1.213–3.187; P=0.006). Conclusions: Ketamine-associated uropathy can involve the upper urinary tract. Patient demographics as well as investigations of UFM, renal function tests, and liver function tests may allow us to identify at-risk patients.

Complete Mesocolic Excision for Right Side Colon Cancer

Chi-wai Lau 대한외과학회 2020 대한외과학회 학술대회 초록집 Vol.2020 No.11

Individual Contribution in Brain-storming: Does Group Composition Make a Difference?

Wai-Kin Yip,Chun-Ming Chow,Kin-Wai Cheng,Chi-Ping Cheuk,Catherine McBride-Chang 대한사고개발학회 2007 The International Journal of Creativity & Problem Vol.17 No.2

Factors affecting individual performance in group tasks such as social loafing and social facilitation have been widely investigated. Past studies compared groups made up of friends or strangers based on prior acquaintance before the experiment, without directly manipulating the level of group cohesiveness. Based on Karau and William’s (1997) rationale about the effect of group cohesiveness on social facilita- tion and social loafing, we tested two hypotheses: (1) When individual members do brain-storming in high cohesiveness group, they work harder and generate more ideas (social facilitation). (2) When individual members do brain-storming in low cohesiveness group, they work less hard and generate fewer ideas (social loafing). Results supported the second hypothesis, but failed to support the first one.

Effect of Post-Weld-Annealing on the Tensile Deformation Characteristics of Laser-Welded NiTi Thin Foil

Chi-Wai Chan,Hau-Chung Man,Tai-Man Yue 대한금속·재료학회 2012 METALS AND MATERIALS International Vol.18 No.4

Laser welding is an important process for fabricating complex components involving NiTi shape memory alloy. As welding is a thermal process, the amount of heat input and the rate of cooling have significant impact on the microstructure and hence the resultant characteristics of NiTi. In this study, the effect of laser welding and post-weld-annealing from 573 K to 1173 K on the thermal phase transformation behaviors,tensile deformation and micro-hardness characteristics of the laser-welded NiTi thin foils were investigated. It was found that the as-welded sample exhibited inferior super-elasticity compared to the base material, and the super-elasticity could be partially restored by annealing at 573 K. On the other hand,annealing of the weldment above the recrystallization temperature would lower the super-elasticity.

ASCI 2022: Report of Scientific Programme

Poon William Wai Lun,Cheung Stephen Chi Wai,Chan Carmen Wing Sze 아시아심장혈관영상의학회 2022 Cardiovascular Imaging Asia Vol.6 No.3

Hypoalbuminemia and obesity class II are reliable predictors of peri-prosthetic joint infection in patient undergoing elective total knee arthroplasty

Man Sheryl Lok-Chi,Chau Wai-Wang,Chung Kwong-Yin,Ho Kevin Ki Wai 대한슬관절학회 2020 대한슬관절학회지 Vol.32 No.-

Background: Malnutrition is a common and modifiable risk factor for postoperative complications and adverse outcomes in orthopedics. The purpose of this study was to identify biomarkers of malnutrition in patients undergoing elective total knee arthroplasty (TKA) that are predictive of adverse in-hospital postoperative complications, to facilitate the identification of at-risk patients for nutritional optimization before surgery. Methods: A total of 624 patients who underwent elective TKA between 2013 and 2017 were evaluated; potential biomarkers of preoperative malnutrition, including hypoalbuminemia (serum albumin < 3.5 g/dL), total lymphocyte count (TLC < 1500 cells/mm3), and body mass index (BMI), were assessed for any association with in-hospital postoperative complications. Results: The prevalence of hypoalbuminemia, low TLC, overweight, obesity class I, and obesity class II were, respectively 2.72%, 33.4%, 14.8%, 44.5%, and 26.9%. There was a significant association between hypoalbuminemia and obesity class II (BMI ≥ 30.0 kg/m2) with rates of peri-prosthetic joint infection, and no significant association between such complications and low TLC, overweight, or obesity class I. Logistic regression analysis showed that patients with hypoalbuminemia or being in obesity class II with gouty arthritis were more likely to suffer from periprosthetic joint infection. Conclusions: Hypoalbuminemia and obesity class II together is a reliable biomarker of preoperative malnutrition for predicting peri-prosthetic joint infection after elective TKA, whereas low TLC, overweight, and obesity class I were not significantly associated with an increased risk of such complications.

Twenty-four months long-term follow-up report on the effect of poly lactic-co-glycolic acid suspension suture in Asian with mild-moderate face laxity

Lam Phoebe Kar Wai,Fung Chi Pun,Lam James Yui,Luk Wang Lung,Lee Alvin Ka Wai,Lee Cheuk Hung,Tam Paul Man Kei,Lau Edwin Kwan Chark 대한미용의학회 2022 대한미용의학회지 Vol.6 No.1

Background: There was evidence of improvement in mid-face laxity using three pairs of suspension sutures in mid-face lifting in our early and mid-term follow-up. Objective: This 24-month prospective follow-up study aimed to determine the efficacy of mid-face lifting and lower jawline contouring using poly lactic-co-glycolic acid (PLGA) sutures in Asian patients. Methods: Ten healthy volunteers received three pairs of 8-cones bidirectional cones sutures at the mid-face. One of the ten volunteers lost to follow-up, and all remaining patients followed up for 24 months. Our primary outcome measure is the change in the facial laxity rating scale (FLRS), an “improvement” defined as at least “one-grade change” in FLRS. Other assessment parameters include the severity of the nasolabial fold (NLF), assessed on the wrinkle severity rating scale (WSRS). The secondary outcome measures were the self-satisfaction rating scale (SSRS) and global aesthetic improvement scale (GAIS), rated by participants at each follow-up interval. Results: A linear improvement in the mid-face was observed almost immediately after treatment, with progressive improvement up to at least 12 months following the intervention and no deterioration by 24 months. This improvement was significant (p<0.05), and the differences between before and after treatment at each follow-up interval were large (Cohen’s d>0.8). Contour improvement for the lower face followed a similar trend, except for a delay in the observable differences at three months (Cohen’s d=0.29, 0.8 at six weeks and three months, respectively). The differences in the level of patient satisfaction were significant (p<0.05) from 6 weeks to 24 months, peaking between 12 and 18 months, based on both the GAIS and SSRS ratings. No observed complications. Conclusion: Mid-facing lifting in Asian patients with mild-to-moderate laxity is safe and effective with PLGA bidirectional cone sutures, with concurrent improvement in the lower face contour and elevated patient satisfaction over the 24-month follow-up period.

An Unusual Cause of Hemoptysis: Congenital Absence of the Right Pulmonary Artery in a Young Male

Chan Victor Siang Hua,Ma Wai Han,Ho Wai Yin,Chan Carmen Wing Sze,Cheung Stephen Chi Wai,Lam Wendy Wai Man 아시아심장혈관영상의학회 2019 Cardiovascular Imaging Asia Vol.3 No.1

Unilateral absent pulmonary artery (UAPA) is rare and can occur in association with cardiovascular anomalies or in isolation. Herein, we describe a case of isolated UAPA in a 14-yearold male patient who presented with hemoptysis secondary to abnormal hypertrophy of collateral vasculature. The patient was successfully treated by endovascular embolization with polyvinyl alcohol particles.

In-Country Language Immersion and the Development of Korean Language Learners’ Intercultural Competence

Wai Meng Chan,Seo Won Chi 국제한국어교육문화재단 2017 국제한국어교육 Vol.3 No.2

외국어교육은 학습자의 상이문화간 능력을 개발하는데 중요한 역할을 한다. 일반적으로 학습자들이 대상 언어 국가에서 외국어 교육과정 연장선으로 교실밖 활동으로 구성된 것이 몰입교육이다. 몰입 교육은 학습자들에게 대상 문화를 직접 체험할 수 있는 기회를 제공한다는 측면에서 상이문화간 능력을 개발하는데 크게 기여한다고 할 수 있다. 즉 몰입 교육은 학 습자들에게 대상 국가의 사회문화 관습을 체험하고 발견할 수 있도록하는 기회를 제시한다는 점이 중요하다. 학습자들은 대상국가의 사회관습을 단지 관찰하는 관찰자의 역할만으로 그치는 것이 아니라 그 사회구성인들과 소통하면서 사회의 일원으로 될 수 있는 것이다. 본고에서 단기 몰입교육이 외국어로 한국어를 배우는 학습자들의 상이문화간 능 력 개발에 얼마나 중요한 역할을 하는지에 초점을 두고 있다. 이 연구 는 양적, 질적 데이터를 가지고 조사했다. 자료는 학습자들이 몰입 교육 프로그램을 참여하기 전과 후로 실시한 설문 조사, 몰입교육 프로그램에 참가한 학습자들이 쓴 일지, 학습자와의 인터뷰, 연구자자의 몰입 교육 수업 참관 일지 및 몰입교육 프로그램의 활동과 관련된 전반적인 내용으로 구성되어 있다. 모든 연구 자료는 Byram (1997)의 상이문화간 숙달도 모델, Lave and Wenger (1991)의 상황학습이론(SLT)와 합법적인 주변인으로 공동체 참여 개념 (LPP)을 기반으로 분석되었다. 분석을 통해 단기 몰입교육이 학습자들의 문화인식과 상이문화간 능력을 배양할수 있도록 하는 지식, 태도, 기술개발에 도움이 된다는 점을 알 수 있었다. 이런 능력 개발은 학습자들이 대상 사회속에서도 주변인의 역할을 잘 할 수 있도록 도움을 줄 수 있을 것이다. 하지만 기존 구성원들과 소 통을 하고 공동체에 일원으로 참여하고자 하는 학습자의 동기와 의지에 따라 결과는 달라질 수 있다는 점 역시 간과할 수 없을 것이다. International Journal of Korean Language Education 3(2), 1-37. Foreign language education can play a pivotal role in the development of one’s intercultural competence. In-country language immersion, a common out-of-class component and extension of the foreign language curriculum, can make a telling contribution in this respect, as it takes learners to the target language country for a first-hand experience of its culture. It affords learners opportunities to explore and discover aspects of the country’s sociocultural practices. In fact, learners will be put in the position not only to observe these practices, but also to partake in them and to interact with members of the target language community. This article focuses on a study of the impact of short-term in-country language immersion on the intercultural development of learners of Korean as a foreign language. Quantitative and qualitative data were collected through pre-/post-immersion questionnaires, journals, interviews, lesson and activity observations, and document inspection. The data were analysed based mainly on Byram’s (1997) model of intercultural competence, and Lave and Wenger’s (1991) Situated Learning Theory and notion of legitimate peripheral participation. The study arrived at the finding that short-term in-country immersion can benefit learners in the development of the knowledge, attitudes and skills for the cultivation of critical cultural awareness and intercultural competence. Such development is often precipitated by learners’ legitimate peripheral participation in the target language community, but is dependent on their motivation and willingness to take up such opportunities for interaction and participation.