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      • KCI등재

        Cap-Assisted Technique versus Conventional Methods for Esophageal Food Bolus Extraction: A Comparative Study

        Mahmoud Wahba,Ghada Habib,Ahmed El Mazny,May Fawzi,Mohamed A. Elfeki,Seham Sabry,Mahommad ELbaz,Sayed M Seif El Nasr 대한소화기내시경학회 2019 Clinical Endoscopy Vol.52 No.5

        Background/Aims: Food bolus impaction is the most common form of esophageal foreign body impaction observed in adults. Clinicalguidelines recommend using the push technique or retrieval methods in such cases. The push technique can cause injuries in certainclinical situations. Notably, conventional retrieval methods are time and effort consuming. Cap-assisted endoscopic extraction of animpacted food bolus is an easy and effective technique; however, more data are needed for its validation. This study compared the capassistedextraction technique with conventional methods. Methods: This prospective observational multicenter study compared the success and en bloc removal rates, total procedure time, andadverse events in both techniques.. Results: The study included 303 patients who underwent food bolus extraction. The push technique was used in 87 patients (28.7%) anda retrieval procedure in 216 patients (71.3%). Cap-assisted extraction was performed in 106 patients and retrieval using conventionalmethods in 110 patients. The cap-assisted technique was associated with a higher rate of en bloc removal (80.2% vs. 15%, p<0.01), shorterprocedure time (6.9±3.5 min vs. 15.7±4.1 min, p<0.001), and fewer adverse events (0/106 vs. 9/110, p<0.001). Conclusions: Cap-assisted extraction showed no adverse events, higher efficacy, and a shorter procedure time compared withconventional retrieval procedures.

      • KCI등재

        Eccentric Versus Concentric Exercises in Patients With Rheumatoid Arthritis and Rotator Cuff Tendinopathy: A Randomized Comparative Study

        Mina Magdy Wahba,Mona Selim,Mohammed Moustafa Hegazy,Rasmia Elgohary,Mohammed Shawki Abdelsalam 대한재활의학회 2023 Annals of Rehabilitation Medicine Vol.47 No.1

        Objective To determine the efficacy of concentric vs. eccentric exercise in improving shoulder function, pain, and tendon characteristics for patients with rheumatoid arthritis and rotator cuff tendinopathy. Methods Forty patients with rheumatoid arthritis and rotator cuff tendinopathy were divided into either concentric or eccentric exercise groups, with 20 patients in each group. Patients received 12 sessions at a pace of 3 sessions per week. Shoulder Pain and Disability Index (SPADI), the visual analogue scale (VAS), supraspinatus and subscapularis thickness, echo pixels, and the Disease Activity Score-28-erythrocyte sedimentation rate (DAS-28-ESR) were assessed at baseline and post-treatment. Results There was a significant difference between the concentric and eccentric groups regarding SPADI and VAS scores in favor of the eccentric group. However, there was no significant difference between the two groups regarding tendon thickness, echo pixels, or DAS-28-ESR. Conclusion Eccentric exercises were more effective than concentric exercises in improving shoulder function and pain intensity. However, neither of the two types of exercises was superior in improving tendon characteristics or disease activity.

      • KCI등재

        Agar-Carrageenan Hydrogel Blend as a Carrier for the Covalent Immobilization of β-D-Galactosidase

        Marwa I. Wahba,Mohamed E. Hassan 한국고분자학회 2017 Macromolecular Research Vol.25 No.9

        κ-Carrageenan (Car) was mixed with agar in order to improve the treated gel’s ability to covalently immobilize enzymes. The treatment process of the produced agar-Car gel involved reacting with both polyethyleneimine and glutaraldehyde so as to provide the functional groups necessary for the covalent binding of enzymes. The positive effect imparted by the addition of Car to agar was confirmed through the statistical Plackett-Burman design (PBD). The PBD was employed to investigate the effects of 11 factors on the preparation of the treated agar-Car gel disks, and the immobilization of β-D-galactosidase (β-gal) onto these disks. The PBD provided recommendations on the levels at which 10 of the tested factors should be employed in the future as these factors were shown to be insignificant. On the other hand, the significant factor, the loading enzyme’s activity, was optimized in order to attain the maximum observed activity of immobilized β-gal which amounted to 166.2 U/g gel. It was also shown that the agar-Car immobilized β-gal maintained 97.7% of its initial observed activity during its fifteenth reusability cycle.

      • SCOPUSKCI등재

        Antinociceptive and anti-inflammatory effects of N-acetylcysteine and verapamil in Wistar rats

        Elberry, Ahmed Abdullah,Sharkawi, Souty Mouner Zaky,Wahba, Mariam Rofaiel The Korean Pain Society 2019 The Korean Journal of Pain Vol.32 No.4

        Background: Antinociceptive anti-inflammatory drugs have many adverse effects. The goal of this investigation is to study the probable anti-inflammatory and analgesic effects of verapamil and N-acetylcysteine (NAC) in experimental rats. Methods: Adult male Wistar rats were randomly divided into 4 groups in the antinociceptive study, each containing 6 rats; the normal control group, which received saline (1 mL/kg); the diclofenac group, which received diclofenac sodium (5 mg/kg); the NAC group, which received NAC (125 mg/kg); and the verapamil group, which received verapamil (8 mg/kg). In the anti-inflammatory study, 5 groups were used, the 4 previous groups with the addition of an edema control group, received saline and were subjected to formalin test. Hot plate latency time was recorded for antinociceptive evaluation. Paw edema thickness and biochemical parameters were recorded for anti-inflammatory evaluation. Results: Administration of NAC showed significant prolongation of hot plate latency time at 1 hour when compared to the control group while verapamil showed a significant prolongation of hot plate latency time at 1 and 2 hours when compared to the control group and NAC group values. Administration of NAC and verapamil significantly decreased paw edema thickness at 2, 4, and 8 hours when compared to edema control values. Regarding biochemical markers, NAC and verapamil significantly decreased serum nitric oxide synthase, C-reactive protein, and cyclooxygenase-2 levels compared to the edema control value. In accordance, a marked improvement of histopathological findings was observed with both drugs. Conclusions: NAC and verapamil have antinociceptive and anti-inflammatory effects comparable to diclofenac sodium.

      • KCI등재

        Determination of the Optical Properties of Bent Optical Fibre by Using an Automatic Fringe Pattern Analysis

        M. A. M. El-Morsy,H. H. Wahba 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.5

        The automatic multiple-beam Fizeau fringes technique with the aid of the slabs model is used to characterize the macroscopic and microscopic optical parameters of the bent optical fibre cladding. The contour line of the interferogram is obtained using one dimensional Fourier transform. The used mathematical expressions based on the consideration of refraction of the beam through the liquid/bent fibre interface. The refractive index profile, the induced birefringence profile and the dispersions are studied along the cladding diameter. The influences of the dispersion parameters such as the oscillation energy E_0 and the dispersion energy Ed for the optical fibre cladding due to bending are investigated. Also the variation occurred in the molecular Polarizability and corresponding parameters are illustrated.

      • KCI등재

        Immune Defense of Rats Immunized with Fennel Honey, Propolis, and Bee Venom Against Induced Staphylococcal Infection

        S.M. Sayed,Ghada A. Abou El-Ella,Nahed M. Wahba,Neveen A. El Nisr,Khaled Raddad,M.F. Abd El Rahman,M.M. Abd El Hafeez,Ahmed Abd El Fattah Aamer 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.3

        The objective of this work was to evaluate the potency of bee product-immunized rats to overcome an induced Staphylococcus aureus infection. Forty rats were divided to eight groups: T1, T3, and T5 received, respectively, fennel honey, ethanol, and aqueous propolis extracts orally, and T2, T4, and T6 were administered the respective materials intraperitoneally; T7 received bee venom by the bee sting technique; and T8 was the control group. All groups were challenged by a bovine clinical mastitis isolate of S. aureus. Each rat received 2mL of broth inoculated with 1×105 colony-forming units/mL intraperitoneally. Two weeks post-induced infection all rats were sacrificed and eviscerated for postmortem inspection and histopathological study. Three rats from T8 and one rat from T7 died before sacrifice. Another two rats, one each in T4 and T5, had morbidity manifestations. The remaining experimental animals showed apparently healthy conditions until time of sacrifice. Postmortem inspection revealed that all T8 rats showed different degrees of skeletal muscle and internal organ paleness with scattered focal pus nodules mainly on lungs and livers. All rats of the treated groups showed normal postmortem features except three rats. A dead rat in group T7 showed focal pus nodules on the lung surface only, whereas the affected two rats in groups T4 and T5 appeared normal except with some pus nodules, but much smaller than in the control, scattered on the hepatic surface and mesentery. Histopathological studies revealed that T8 rats had typical suppurative bronchopneumonia and or severe degenerative and necrobiotic changes in hepatic tissues. Three affected rats of the treated groups showed slight bronchopneumonia or degenerative hepatic changes only. The other animals of the treated groups showed completely normal parenchymatous organs with stimulated lymphatic tissues. It was concluded that all tested previously bee product-immunized rats could significantly challenge the induced S. aureus infection (P<.01). The effects were more pronounced in rats that had received fennel honey solution.

      • KCI등재

        Immune Defense of Rats Immunized with Fennel Honey, Propolis, and Bee Venom Against Induced Staphylococcal Infection

        Sayed, S.M.,El-Ella, Ghada A. Abou,Wahba, Nahed M.,Nisr, Neveen A. El,Raddad, Khaled,Rahman, M.F. Abd El,Hafeez, M.M. Abd El,Aamer, Ahmed Abd El Fattah The Korean Society of Food Science and Nutrition 2009 Journal of medicinal food Vol.12 No.3

        The objective of this work was to evaluate the potency of bee product-immunized rats to overcome an induced Staphylococcus aureus infection. Forty rats were divided to eight groups: T1, T3, and T5 received, respectively, fennel honey, ethanol, and aqueous propolis extracts orally, and T2, T4, and T6 were administered the respective materials intraperitoneally; T7 received bee venom by the bee sting technique; and T8 was the control group. All groups were challenged by a bovine clinical mastitis isolate of S. aureus. Each rat received 2mL of broth inoculated with $1{\times}10^5$ colony-forming units/mL intraperitoneally. Two weeks post-induced infection all rats were sacrificed and eviscerated for postmortem inspection and histopathological study. Three rats from T8 and one rat from T7 died before sacrifice. Another two rats, one each in T4 and T5, had morbidity manifestations. The remaining experimental animals showed apparently healthy conditions until time of sacrifice. Postmortem inspection revealed that all T8 rats showed different degrees of skeletal muscle and internal organ paleness with scattered focal pus nodules mainly on lungs and livers. All rats of the treated groups showed normal postmortem features except three rats. A dead rat in group T7 showed focal pus nodules on the lung surface only, whereas the affected two rats in groups T4 and T5 appeared normal except with some pus nodules, but much smaller than in the control, scattered on the hepatic surface and mesentery. Histopathological studies revealed that T8 rats had typical suppurative bronchopneumonia and or severe degenerative and necrobiotic changes in hepatic tissues. Three affected rats of the treated groups showed slight bronchopneumonia or degenerative hepatic changes only. The other animals of the treated groups showed completely normal parenchymatous organs with stimulated lymphatic tissues. It was concluded that all tested previously bee product-immunized rats could significantly challenge the induced S. aureus infection (P < .01). The effects were more pronounced in rats that had received fennel honey solution.

      • KCI등재

        Antinociceptive and anti-inflammatory effects of N-acetylcysteine and verapamil in Wistar rats

        Ahmed Abdullah Elberry,Souty Mouner Zaky Sharkawi,Mariam Rofaiel Wahba 대한통증학회 2019 The Korean Journal of Pain Vol.32 No.4

        Background: Antinociceptive anti-inflammatory drugs have many adverse effects. The goal of this investigation is to study the probable anti-inflammatory and analgesic effects of verapamil and N-acetylcysteine (NAC) in experimental rats. Methods: Adult male Wistar rats were randomly divided into 4 groups in the antinociceptive study, each containing 6 rats; the normal control group, which received saline (1 mL/kg); the diclofenac group, which received diclofenac sodium (5 mg/kg); the NAC group, which received NAC (125 mg/kg); and the verapamil group, which received verapamil (8 mg/kg). In the anti-inflammatory study, 5 groups were used, the 4 previous groups with the addition of an edema control group, received saline and were subjected to formalin test. Hot plate latency time was recorded for antinociceptive evaluation. Paw edema thickness and biochemical parameters were recorded for anti-inflammatory evaluation. Results: Administration of NAC showed significant prolongation of hot plate latency time at 1 hour when compared to the control group while verapamil showed a significant prolongation of hot plate latency time at 1 and 2 hours when compared to the control group and NAC group values. Administration of NAC and verapamil significantly decreased paw edema thickness at 2, 4, and 8 hours when compared to edema control values. Regarding biochemical markers, NAC and verapamil significantly decreased serum nitric oxide synthase, C-reactive protein, and cyclooxygenase- 2 levels compared to the edema control value. In accordance, a marked improvement of histopathological findings was observed with both drugs. Conclusions: NAC and verapamil have antinociceptive and anti-inflammatory effects comparable to diclofenac sodium.

      • KCI등재

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