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Vyacheslav Yu. Cherebillo,Andrei Yu. Elizarov,Andrei V. Polegaev 한국뇌신경과학회 2015 Experimental Neurobiology Vol.24 No.3
A possibility to use the Membrane-Introduction Mass Spectrometry (MIMS) with membrane separator interface has evolved into a powerful method for measurement of anaesthetic agents absolute concentration in blood plasma and cerebrospinal fluid for the study of blood-brain barrier (BBB) properties. Recent advanced a new membrane material was used for drug concentration measurement in biologic fluids. A hydrophobic membrane was used in the interface to separate anaesthetic agents from biological fluids: inhalational anaesthetic desflurane,hypnotic propofol, analgesic fentanyl. The selective detection of volatile anesthetic agents in blood does not require long-term sample processing before injecting the sample into mass-spectrometer interface, in contrast to chromatographic methods. Mass-spectrometric interface for the measurement of anaesthetic agent concentration in biological fluids (blood plasma and cerebrospinal fluid) is described. Sampling of biological fluids was performed during balanced inhalational (desflurane, fentanyl) anaesthesia and total intravenous (propofol, fentanyl) anaesthesia.
Vyacheslav Tuzlukov 제어로봇시스템학회 2008 제어로봇시스템학회 국제학술대회 논문집 Vol.2008 No.10
We investigate the multiuser generalized detector, which is constructed based on the generalized approach to signal processing in noise [1]?5], for uniformly quantized synchronous code division multiple access (CDMA) signals in additive white Gaussian noise channels of wireless sensor networks and compare with minimum mean-square error (MMSE) multiuser receiver discussed in [6]. The input/output relationship of the quantizer is represented by the gain plus the additive noise model. Based on this model, we derive the weight vector and the output signal-to-interference ratio (SIR) of the multiuser generalized detector. The effects of quantization and sampling of the multiuser generalized detector performance is characterized in a single parameter named “quivalent noise variance”which is a function of the sum of each active user’ signal-to-noise ratio (SNR), processing gain, and the number of quantization and sampling levels. The optimal quantizer step size, which maximizes the multiuser generalized detector output SNR, is also determined. Simulation results validate the accuracy of our theoretical analysis and confirms a superiority of employment of the multiuser generalized detector over minimum mean-square error multiuser receiver, which is analyzed in [6].
Bi-criteria Aircraft Trajectory Optimization in Implementing the Area Navigation Concept
Vyacheslav Erokhin,Boris Lezhankin,Tatyana Portnova 한국항공우주학회 2021 International Journal of Aeronautical and Space Sc Vol.22 No.4
To solve a problem of bi-criteria optimization of an aircraft flight trajectory using the data of satellite navigation systems, the authors suggest an approach based on the game theory methods. The target was set to organize trajectory control with two partial criteria of optimality (desired track deviation and position-fixing error) minimized simultaneously. It is shown that the minima of individual partial criteria are generally achieved with different control inputs and hence with different flight path parameters so there is a need to form an additional strategy for decision making in a bi-criteria optimization problem taking into account existing restrictions. Based on the multi-criteria optimization methods, an algorithm for aircraft trajectory control was synthesized. The comparative analysis of the research results shows that the synthesized algorithms of optimal control based on the suggested approach make it possible to find a compromise solution for a multi-criteria trajectory optimization problem in the area of global navigational satellite system augmentation. Proposals were drawn up to construct spatial programmed trajectories aiming to high-accuracy navigational sightings.
Applicability of exponential stress-strain models for carbonate rocks
Palchik, Vyacheslav Techno-Press 2018 Geomechanics & engineering Vol.15 No.3
Stress-strain responses of weak-to-strong carbonate rocks used for tunnel construction were studied. The analysis of applicability of exponential stress-strain models based on Haldane's distribution function is presented. It is revealed that these exponential equations presented in transformed forms allow us to predict stress-strain relationships over the whole pre-failure strain range without mechanical testing of rock samples under compression using a press machine and to avoid measurements of axial failure strains for which relatively large values of compressive stress are required. In this study, only one point measurement (small strain at small stress) using indentation test and uniaxial compressive strength determined by a standard Schmidt hammer are considered as input parameters to predict stress-strain response from zero strain/zero stress up to failure. Observations show good predictive capabilities of transformed stress-stress models for weak-to-strong (${\sigma}_c$ <100 MPa) heterogeneous carbonate rocks exhibiting small (< 0.5 %), intermediate (< 1 %) and large (> 1 %) axial strains.