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      • KCI등재

        Chinese and Indian Multinationals: A Firm-Level Analysis of their Investments in Europe

        Vito Amendolagine,Claudio Cozza,Roberta Rabellotti 연세대학교 동서문제연구원 2015 Global economic review Vol.44 No.4

        This paper contributes to the literature on Chinese and Indian multinationals investing in Europe through an empirical investigation about their identity, their characteristics and the association between their features and their international strategies. The investigation exploits a database, named EMENDATA (Emerging Multinationals’ Events and Networks DATAbase), at the level of the investing firms. In relation to the mode of entry, we find that greenfield investments are a more likely option for large-sized companies. Moreover a high propensity for innovation is associated with a high probability to enter with an acquisition and with technological asset-seeking investments. Finally, high profitability is needed to invest in the EU-core countries.

      • KCI등재

        War Games: North Korea's Reaction to US and South Korea Military Exercises

        Vito D'Orazio 동아시아연구원 2012 Journal of East Asian Studies Vol.12 No.2

        Since 1976, the militaries of the United States and South Korea have been holding routine joint military exercises (JMEs) for the purposes of military training and deterrence against North Korea. These exercises are frequently cited as a cause of tension on the peninsula, causing North Korea to escalate its conflictual rhetoric and behavior. I empirically assess this claim using new data on US-ROK JMEs and machine-coded event data collected by the Integrated Crisis Early Warning System. The findings show that North Korea does not systematically escalate its conflictual rhetoric or behavior during or near the occurrence of JMEs. The result s hold for both low-and high-intensity exercises and for rhetoric that has the United States and South Korea as its target.

      • KCI등재

        In vitro toxicological assessment of PhSeZnCl in human liver cells

        di Vito Raffaella,Levorato Sara,Fatigoni Cristina,Acito Mattia,Sancineto Luca,Traina Giovanna,Villarini Milena,Santi Claudio,Moretti Massimo 한국독성학회 2023 Toxicological Research Vol.39 No.1

        Phenylselenenylzinc chloride (PhSeZnCl) is an air-stable selenolate, easily synthesizable through oxidative insertion of elemental zinc into the Se-halogen bond of the commercially available phenylselenyl chloride. PhSeZnCl was shown to possess a marked GPx-like activity both in NMR and in vitro tests, and to effectively react with cellular thiols, and was supposed for a potential use in the chemotherapy of drug-resistant cancers. However, activity of PhSeZnCl in hepatic cells has never been tested before now. In this in vitro approach, we evaluated the cytotoxic, genotoxic, and apoptotic activities, as well as the effects on cell cycle of PhSeZnCl in two preclinical hepatic models, namely HepG2 and HepaRG cells. Results showed that cell viability of HepG2 and HepaRG cells decreased in a dose-dependent manner, with a more marked effect in HepG2 tumour cells. Moreover, treatment with 50 μg/mL PhSeZnCl caused an increase of primary DNA damage (4 h) and a statistically significant increase of HepG2 cells arrested in G2/ M phase. In addition, it altered mitochondrial membrane potential and induced chromosomal DNA fragmentation (24 h). In HepaRG cells, PhSeZnCl was able to determine a cell cycle-independent induction of apoptosis. Particularly, 50 μg/mL induced mitochondrial membrane depolarization after 24 h and apoptosis after 4 h treatment. Futhermore, all PhSeZnCl concentrations tested determined a significant increase of apoptotic cells after 24 h. Apoptosis was also highlighted by the detection of active Caspase-3 by Western Blot analysis after 24 h exposure. In conclusion, this first toxicological assessment provides new insights into the biological activity of PhSeZnCl in preclinical hepatic models that will be useful in future safety assessment investigation of this compound as a potential pharmaceutical.

      • KCI등재

        The fate of overfilling in root canal treatments with long-term follow-up: a case series

        Malagnino Vito Antonio,Pappalardo Alfio,Plotino Gianluca,Carlesi Teocrito 대한치과보존학회 2021 Restorative Dentistry & Endodontics Vol.46 No.2

        This study describes 6 cases of endodontic overfilling with successful clinical outcomes during long-term (up to 35 years) radiographic follow-up. Successful endodontic treatment depends on proper shaping, disinfection, and obturation of root canals. Filling materials should completely fill the root canal space without exceeding the anatomical apex. Overfilling may occur when the filling material extrudes into the periapical tissues beyond the apex. The present case series describes 6 root canal treatments in which overfilling of root canal sealer and gutta-percha accidentally occurred. Patients’ teeth were periodically checked with periapical radiographs in order to evaluate the outcomes during long-term follow-up. All cases showed healing and progressive resorption of the extruded materials in the periapex. The present cases showed that if a 3-dimensional seal was present at the apical level, overfilling did not negatively affect the long-term outcomes of root canal treatment.

      • KCI등재

        Upper eyelid Merkel cell carcinoma treated with neoadjuvant chemotherapy and surgical excision

        Toto, Vito,Colapietra, Alfredo,Alessandri-Bonetti, Mario,Vincenzi, Bruno,Devirgiliis, Valeria,Panasiti, Vincenzo,Persichetti, Paolo Korean Cleft Palate-Craniofacial Association 2019 Archives of Craniofacial Surgery Vol.20 No.2

        Merkel cell carcinoma is a rare cutaneous carcinoma, featured by an aggressive clinical course and a mortality rate of 28% at 2 years. A 71-year-old female was affected by a 4.1-cm-wide locally advanced Merkel cell carcinoma of the upper eyelid, previously misdiagnosed as chalazion, with involvement of the extraocular muscles. Although the tumor showed a macroscopic spontaneous regression in size after the incisional biopsy, the mass was treated with neoadjuvant chemotherapy and surgical excision. Good functional and aesthetic result with preservation of the eyeball and absence of tumor recurrence were achieved at 3-year follow-up. In our experience, the combination of the inflammatory cascade due to the incisional biopsy and neoadjuvant chemotherapy led to the regression of a locally advanced large Merkel cell carcinoma of the eyelid.

      • KCI등재후보

        Some Considerations around time in Electro-acoustic music

        Massimo Vito Avantaggiato 한국전자음악협회 2022 에밀레 Vol.20 No.-

        In this article we’ve analysed some time concepts, applying them to a selection of electroacoustic pieces of different aesthetics. Some differences are pointed out: between hors-temps and en-temps with specific application to the repertoire; the relationship between χρόνος (Chrónos) and καιρός (Kairós) and their influence on the compositional experience and on the approaches used to analyse electroacoustic pieces. The fact that acousmatic music is characterized by a sufficient degree of abstraction with reference to the more traditional musical parameters, does not lead us to the conclusion that the management of time cannot be also considered at an analytical level. We’ve cited Obst’s Crystal World cycle as an emblematic case. In this cycle, time and its management are important on a multidimensional scale: this leads us to make further considerations on analytical techniques, its limits and its possible developments. Other references concern the musical repertoire by J. Adams; J. Alvarez; F. Bayle; F. Donatoni; J. Harrison; R. Minsburg; F. Otondo; M. Rodrigue

      • KCI등재

        Feeding of Dehulled-micronized Faba Bean (Vicia faba var. minor) as Substitute for Soybean Meal in Guinea Fowl Broilers: Effect on Productive Performance and Meat Quality

        Vincenzo Tufarelli,Vito Laudadio 아세아·태평양축산학회 2015 Animal Bioscience Vol.28 No.10

        The present study aimed to assess the effect of dietary substitution of soybean meal (SBM) with dehulled-micronized faba bean (Vicia faba var. minor) in guinea fowl broilers on their growth traits, carcass quality, and meat fatty acids composition. In this trial, 120 day-old guinea fowl keets were randomly assigned to two treatments which were fed from hatch to 12 weeks of age. Birds were fed two wheat middlings-based diets comprising of a control treatment which contained SBM (78.3 g/kg) and a test diet containing dehulled-micronized faba bean (130 g/kg) as the main protein source. Substituting SBM with faba bean had no adverse effect on growth traits, dressing percentage, or breast and thigh muscles relative weight of the guinea fowls. Conversely, a decrease (p<0.05) of abdominal fat was found in guinea fowls fed the faba bean-diet. Breast muscle of birds fed faba bean had higher L* score (p<0.05) and water-holding capacity (p<0.05) than the SBM control diet. Meat from guinea fowls fed faba bean had less total lipids (p<0.05) and cholesterol (p<0.01), and higher concentrations of phospholipids (p<0.01). Feeding faba bean increased polyunsaturated fatty acid concentrations in breast meat and decreased the saturated fatty acid levels. Moreover, dietary faba bean improved the atherogenic and thrombogenic indexes in guinea fowl breast meat. Results indicated that substitution of SBM with faba bean meal in guinea fowl diet can improve carcass qualitative traits, enhancing also meat lipid profile without negatively affecting growth performance.

      • KCI등재

        An outbreak of neonatal enteritis in buffalo calves associated with astrovirus

        Paolo Capozza,Vito Martella,Gianvito Lanave,Cristiana Catella,Georgia Diakoudi,Farzad Beikpour,Michele Camero,Barbara Di Martino,Giovanna Fusco,Anna Balestrieri,Krisztian Banyai,Giuseppe Campanile 대한수의학회 2021 Journal of Veterinary Science Vol.22 No.6

        Background: Enteritis of an infectious origin is a major cause of productivity and economic losses to cattle producers worldwide. Several pathogens are believed to cause or contribute to the development of calf diarrhea. Astroviruses (AstVs) are neglected enteric pathogens in ruminants, but they have recently gained attention because of their possible association with encephalitis in humans and various animal species, including cattle. Objectives: This paper describes a large outbreak of neonatal diarrhea in buffalo calves (Bubalus bubalis), characterized by high mortality, which was associated with an AstV infection. Methods: Following an enteritis outbreak characterized by high morbidity (100%) and mortality (46.2%) in a herd of Mediterranean buffaloes (B. bubalis) in Italy, 16 samples from buffalo calves were tested with the molecular tools for common and uncommon enteric pathogens, including AstV, kobuvirus, and torovirus. Results: The samples tested negative for common enteric viral agents, including Rotavirus A, coronavirus, calicivirus, pestivirus, kobuvirus, and torovirus, while they tested positive for AstV. Overall, 62.5% (10/16) of the samples were positive in a single round reverse transcription polymerase chain reaction (PCR) assay for AstV, and 100% (16/16) were positive when nested PCR was performed. The strains identified in the outbreak showed a clonal origin and shared the closest genetic relationship with bovine AstVs (up to 85% amino acid identity in the capsid). Conclusions: This report indicates that AstVs should be included in a differential diagnosis of infectious diarrhea in buffalo calves.

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