Hypopituitarism and Legg-Calve-Perthes disease related to difficult delivery

Veysel Nijat Bas,Salih Uytun,Ümit Erkan Vurdem,Yasemin Altuner Torun 대한소아청소년과학회 2015 Clinical and Experimental Pediatrics (CEP) Vol.58 No.7

Legg-Calve-Perthes (LCP) disease is characterized by idiopathic avascular osteonecrosis of the epiphysis of the femur head. The main factor that plays a role in the etiology of the disease is decreased blood flow to the epiphysis. Many predisposing factors have been suggested in the etiology of LCP disease, and most have varying degrees of effects. Here we present the case of a boy aged 4 years and 10 months with complaints of short stature and a diagnosis of multiple hypophyseal hormone deficiency, in whom LCP disease and difficult birth-related pituitary stalk interruption syndrome were identified by anamnesis. The present case revealed that LCP disease and hypophyseal hormone deficiency could be secondary to difficult birth and that LCP disease could be secondary to insulin-like growth factor 1 deficiency. Additionally, to the best of our knowledge there is no published case on the relation between LCP disease and insulin-like growth factor 1 deficiency. Therefore, we believe that this case is worthy of presentation.

Adaptive Formation Control and Target Tracking in a Class of Multi-Agent Systems

Veysel Gazi,Barı? Fidan 제어로봇시스템학회 2013 제어로봇시스템학회 국제학술대회 논문집 Vol.2013 No.10

In this article we develop a direct adaptive fuzzy control based methodology for formation control and target tracking in a class of multi-agent systems with nonlinear and uncertain dynamics. The agents are assumed to be able to measure only their relative position to the other agents and the target and high gain observers are applied to estimate the derivatives of the combined tracking and formation errors. Various formation maneuvers such as contraction/expansion, rotation, and reconfiguration of the formation are also considered. Bounding and sliding mode control terms are used to guarantee stability and robust performance. Simple numerical simulations are also provided to verify the effectiveness of the algorithm.

Critical buckling load optimization of the axially graded layered uniform columns

Veysel Alkan 국제구조공학회 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.54 No.4

This study presents critical buckling load optimization of the axially graded layered uniform columns. In the first place, characteristic equations for the critical buckling loads for all boundary conditions are obtained using the transfer matrix method. Then, for each case, square of this equation is taken as a fitness function together with constraints. Due to explicitly unavailable objective function for the critical buckling loads as a function of segment length and volume fraction of the materials, especially for the column structures with higher segment numbers, initially, prescribed value is assumed for it and then the design variables satisfying constraints are searched using Differential Evolution (DE) optimization method coupled with eigen-value routine. For constraint handling, Exterior Penalty Function formulation is adapted to the optimization cycle. Different boundary conditions are considered. The results reveal that maximum increments in the critical buckling loads are attained about 20% for cantilevered and pinned-pinned end conditions and 18% for clamped-clamped case. Finally, the strongest column structure configurations will be determined. The scientific and statistical results confirmed efficiency, reliability and robustness of the Differential Evolution optimization method and it can be used in the similar problems which especially include transcendental functions.

Poster Session : PS 0116 ; Cardiology : Severe Hyperkalemia and Lower Extermity Paralysis without Any Ecg Changes: A Case Report

( Veysel Ozalper ),( Ibrahim Cetindagli ),( Ergenekon Karagoz ),( Emrullah Solmazgul ),( Cihan Top ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Objective: Hyperkalemia is a common and serious clinical problem that occurs often due to impaired urinary potassium excretion because of acute or chronic kidney disease or drugs that effect renin-angiotensin-aldosterone axis. We report a hyperkalemic patient with 9.0mEq/L without any ECG changes. Case Report: A 86-year-old-woman suffering fatigue within two days had admitted emergency service because of sudden bilateral lower extremity paralysis. She had esential hypertension, ischemic heart disease and chronic kidney disease and was using Spironolactone, silazopril, asetilsalisilik, isosorbid-5-mononitrat ve karvedilol. Initial neurological examination of extremities was; 2/5 of lower extremity, 4/5 of upper extremity. Initial laboratory fi ndings potassium:9,1mmol/L, sodium:141mmol/L, creatinine: 1,9mg/dl. In his arterial blood gas analyse, pH:7.27, HCO3:16mEq/L, pCO2:30mm- Hg, potassium:9,1mmol/L. Spironolactone and silazopril treatment had stopped. With an intensive electrolyte-follow-up, She was commenced on intravenous fl uid, injection calcium gluconate and glucose/insulin infusion. Within two hours of treatment her potassium level decreased by 1.5 mmol/L. After eight hours of intensive treatment, potassium level reached below 6,5mEq/L. Five Days later, after three days of close follow-up with normal potassium level, the patient had discharged. Conclusion: ECG differancies like fl attening in U wawe, expansion in QRS, taper in T wawe, arrhytmias, asystoles can be seen in hypercalemia. Especially in the circumstances that serum potassium level is above 8 mEq/L ECG differancy is expected to be seen. So that, it is suggested that biochemical elevation in hypercalemic cases is verifi ed with ECG. Although it is rarely seen like in our cases, it shouldn`t be forgotten that severe hypercalemia can be seen without ECG differancy.

Polyglandular Autoimmune Syndrome Type-Ii Presented with Acute Renal Injury

( Veysel Ozalper ),( Ibrahim Cetindagli ),( Omer Tekin ),( Yalcin Onem ),( Yusuf Hancerli ),( Eylem Cagiltay ),( Barbaros Basbug ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Introduction: Polyglandular autoimmune syndrome (PAS) is a rare disease, characterized by failure of more than two endocrine glands. Type-II of this syndrome is the most common of the immunoendocrinopathy syndromes and characterized by the obligatory occurrence of autoimmune Addison disease in combination with thyroid autoimmune diseases and/or type-I diabetes mellitus. We report a case of PAS-TypeII presented with prerenal acute renal failure. Case Report: A twenty-two-year-old man had a hyperpigmentation of gingiva within three months, fatigue and amnesia within two months, emesis and vomit within one months, admitted because of persistent vomiting and ten kilogram weight loss. Initial laboratory fi ndings were: urea:87mg/dl, kreatinin:1.31mg/dl, sodium:125mmol/L, potassium: 5.6mmol/L, albumin:4.16g/dl, calcium:123mg/dl. In his arterial blood gas analyse, he had a normal anion gap metabolic asidosis. pH:7.24, HCO3:12.8mEq/L, pCO2:30mm- Hg. He had a prerenal acute renal injury because of persistent vomiting. Other laboratory fi ndings were Hemoglobine:12.9g/dl, TSH:0,004 uIU/ml, FreeT4:2,16ng/dl, Anti-TPO:876 IU/ml, AntiThyroglobulin:9,72IU/ml, Cpeptid:0,27ng/ml, Kortizol:0,1ug/dl, ACTH:22,8pg/ml, HbA1c: %4,7.. A thyroid-scintigraphy showed diffuse homogenous thyroid involvement. His pituitary magnetic-resonance-imaging, thoracoabdominal- tomography and esophagogastroscopy was normal. Based on his fi ndings above and intravenous ACTH stimulation test, adrenal insuffi ency and otoimmune thyroiditis were diagnosed. General condition improved gradually following the administration of hydrocortisone, fl udrocortisone, thyromazol, propranolol. Conclusions: As a conclusion, in persistant vomiting patients, endocrine functions must be performed. A patient who presents with a single autoimmune diseases must be considered at risk of other autoimmune diseases. High index of suspicion, early recognition and treatment can be life-saving, particularly when there is adrenal and thyroid component.

UMV control via FOSMO

Veysel Ozbulur 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.9

In this work, the speed and direction angle of an unmanned vehicle (UMV) are controlled by using a sliding mode controller (SMC). However, no mechanical speed or position sensor is used to control the speed and direction angle of the UMV. The speed and direction angle of the UMV are estimated using the fractional-order sliding mode observer (FOSMO), wherein the real UMV motor currents and voltages are measured by sensors and the kinematic modal of the UMV is used. The angular speeds of the UMV are approximated with the help of the estimated and real UMV motor currents. Then, the estimated speed and direction angle of the UMV are approximated by estimated angular speed of the UMV and those produced by the FOSMO are used in the SMC, which controls the speed and direction angle of a UMV. Given that fractional-order differential equations and algorithms are used in FOSMO, a more precise control than that in other controllers that use full-order differential equations is achieved. Lyapunov stability theory is also used to establish stability conditions for the observer. Experimental results show that the proposed observer can be perfectly implemented without a mechanical or position sensor and robustly follows different complex reference trajectories.

Evaluation of Birecik Basin Flood Detection with GIS Assisted AHP Methods

Veysel Aslan 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.7

In addition to the uncontrolled and rapid urbanization, irregular rainfall causes naturalcalamities like overflood. In an effort to stop the loses caused by these floods and to reducetheir damage, it is needful to model the streams made in areas with intense urbanization andcreating flood maps, which will create a suitable environment for investigations. It is vitallyimportant to work on the computation of flood flows and the making distribution maps. Birecik basin hydrological and hydraulic model was created in this context. Data such as basinarea, elevation, slope, relief, land use, soil type and stream paths were modeled in ArcMap10.2 environment. Then, HEC-GeoRAS and Hec-Ras techniques were used for hydrologicaland hydraulic modeling, respectively. Birecik reclamation creek was approached holisticallyfrom a geographical point of view, and the factors affecting the flood (such as precipitation,slope, land use-vegetation, soil, proximity to river networks) were ranked among themselves. These were reclassified according to the data obtained in the AHP application and a flood riskanalysis map was created in the Geographical Information Systems environment.

Static analysis of laminated and sandwich composite doubly-curved shallow shells

Veysel Alankaya,Ahmet Sinan Oktem 국제구조공학회 2016 Steel and Composite Structures, An International J Vol.20 No.5

A new analytical solution based on a third order shear deformation theory for the problem of static analysis of cross-ply doubly-curved shells is presented. The boundary-discontinuous generalized double Fourier series method is used to solve highly coupled linear partial differential equations with the mixed type simply supported boundary conditions prescribed on the edges. The complementary boundary constraints are introduced through boundary discontinuities generated by the selected boundary conditions for the derivation of the complementary solution. The numerical accuracy of the solution is compared by studying the comparisons of deflections, stresses and moments of symmetric and anti-symmetric laminated shells with finite element results using commercially available software under uniformly distributed load. Results are in good agreement with finite element counterparts. Additional results of the symmetric and anti-symmetric laminated and sandwich shells under single point load at the center and pressure load, are presented to provide data for the unsolved boundary conditions, benchmark comparisons and verifications.

Investigation of Microstructure of Aluminum Based Composite Material Obtained by Mechanical Alloying

Veysel Erturun,Sezer Çetin,Oguzhan Sahin 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.6

Aluminum, zinc, magnesium, copper and silicon carbide powders were alloyed by mechanical alloying (MA) at certainratios and for different periods. At the same time, the zinc effect on the microstructure was investigated by keeping the ratioof zinc in the mixture at different ratios for each mixture. X-ray diffraction (XRD) analysis was carried out to investigate thedifferent phases. Analyzes of the microstructures of alloys with different alloying times were investigated by scanning electronmicroscopy (SEM) and optical microscope. The powders obtained by the MA method sintered in an argon atmosphere,which is a protective gas, to obtain billets from the powder samples. Finally, the billets were polished and then examinedunder an optical microscope.

Additional Surgical Method Aimed to Increase Distractive Force during Occipitocervical Stabilization : Technical Note

Antar, Veysel,Turk, Okan The Korean Neurosurgical Society 2018 Journal of Korean neurosurgical society Vol.61 No.2

Objective : Craniovertebral junctional anomalies constitute a technical challenge. Surgical opening of atlantoaxial joint region is a complex procedure especially in patients with nuchal deformity like basilar invagination. This region has actually very complicated anatomical and functional characteristics, including multiple joints providing extension, flexion, and wide rotation. In fact, it is also a bottleneck region where bones, neural structures, and blood vessels are located. Stabilization surgery regarding this region should consider the fact that the area exposes excessive and life-long stress due to complex movements and human posture. Therefore, all options should be considered for surgical stabilization, and they could be interchanged during the surgery, if required. Methods : A 53-year-old male patient applied to outpatients' clinic with complaints of head and neck pain persisting for a long time. Physical examination was normal except increased deep tendon reflexes. The patient was on long-term corticosteroid due to an allergic disease. Magnetic resonance imaging and computed tomography findings indicated basilar invagination and atlantoaxial dislocation.The patient underwent C0-C3-C4 (lateral mass) and additional C0-C2 (translaminar) stabilization surgery. Results : In routine practice, the sites where rods are bound to occipital plates were placed as paramedian. Instead, we inserted lateral mass screw to the sites where occipital screws were inserted on the occipital plate, thereby creating a site where extra rod could be bound.When C2 translaminar screw is inserted, screw caps remain on the median plane, which makes them difficult to bind to contralateral system. These bind directly to occipital plate without any connection from this region to the contralateral system.Advantages of this technique include easy insertion of C2 translaminar screws, presence of increased screw sizes, and exclusion of pullout forces onto the screw from neck movements. Another advantage of the technique is the median placement of the rod; i.e., thick part of the occipital bone is in alignment with axial loading. Conclusion : We believe that this technique, which could be easily performed as adjuvant to classical stabilization surgery with no need for special screw and rod, may improve distraction force in patients with low bone density.