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Jeane Marina D’Souza,Venkat Varun Velpula,K. R. Guruprasad 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.7
In this paper, we consider a problem of autonomous search using single or multiple Unmanned Ariel Vehicles (UAVs) mounted with downward-facing cameras. A model of the effectiveness of the search sensor, camera, in this case, is essential for developing strategies for optimal deployment and path planning of UAVs for efficient search. The probability of detection of a target of interest as a function of its distance from the point directly below the camera is used to model the search effectiveness. We carried out experiments and obtained a search effectiveness model for a camera in the laboratory environment using ArUco markers and triangular shapes as targets.
Suresh Bandari,Sharath Sunkavalli,Basanth Babu Eedara,Karthik Yadav Janga,Ashok Velpula,Raju Jukanti 한국화학공학회 2016 Korean Journal of Chemical Engineering Vol.33 No.3
Liquid self-nanoemulsifying drug delivery systems (L-SNEDDS) of docetaxel were prepared using varying ratios of Capmul PG 8 NF (oil), Cremophor EL (surfactant) and Transcutol-P (co-surfactant). The optimized L-SNEDDS (L11) was transformed into self-nanoemulsifying powder (SNEP) by physical adsorption on to Neusilin US2 and evaluated for dissolution behavior, in vitro cytotoxicity and in vivo oral bioavailability. Optimized L-SNEDDS (L11) composed of 50% of oil, 41.7% of surfactant and 8.3% co-surfactant produced stable emulsion with smaller globules (43±3 nm). In vitro dissolution studies showed the rapid drug release within 5min (95.42±1%) from SNEPN. In vitro cytotoxicity assessed by the MTT assay using MCF-7 human breast cancer cell lines revealed that L-SNEDDS significantly reduced the IC50 value and was 2.3 times lower than the pure docetaxel. Further, the oral bioavailability studies in male Wistar rats showed higher Cmax values following treatment with SNEPN (0.98±0.13 μg/mL) and L-SNEDDS (1.09± 0.06 μg/mL) compared to pure docetaxel (0.37±0.04 μg/mL).