국내 서식 야생 고양이의 톡소플라즈마중, 한타바이러스 감염증 및 리켓치아성 질병에 대한 혈청학적 조사

한동운,이정길,강문일,장환,김희선,김홍집,위성환 한국수의공중보건학회 1999 예방수의학회지 Vol.23 No.4

국내 서식 야생 고양이의 톡소플라즈마증, 한타바이러스 감염증 및 리켓치아성 질병에 대한 혈청학적 조사

한동운(Dong Un Han),이정길(Chung Gil Lee),강문일(Mun Il Kang),장환(Hwan Jang),김희선(Hee Sun Kim),김홍집(Hong Jib Kim),위성환(Sung Hwan wee) 한국예방수의학회 1999 예방수의학회지 Vol.23 No.4

1995년 11월부터 1997년 10월까지 2년간 전국을 5개 구역으로 구분하여 야외에서 서식중인 고양이 212두를 포획하여 톡소플라스마와 한타바이러스 및 리켓치아에 대한 항체보유율을 조사하였다. 톡소플라스마 항체 검출을 위하여 포획된 고양이의 혈청에 대하여 Latex 응집반응을 실시한 결과 79.3% (168/212)가 음성소견인 32배 미만의 항체가를 나타냈고 20.7% (44/212)에서 32배 이상의 항체가를 나타냈다. 항체 양성소견을 보인 44두에 대한 항체 역가별 분포도는 1:32~256 배가 38.6%, 1:512~2,048 배가 31.8% 그리고 4,096 배 이상이 29.5%로 역가별로는 유의성 있는 차이를 보이지 않았다(P<0.05). 국내의 야외 고양이의 톡소플라스마에 대한 암수간의 항체 보유율의 차이는 수컷이 22.3%(23/103)로 암컷의 19.3%(21/109)에 비해 다소 높게 나타났다. 고양이의 지역별 항체보유율은 서울ㆍ경기(31.9%)가 가장 높았고, 다음으로 강원(24.4%), 전라(17.5%), 충청(15.0%)지역의 순으로 나타났으며, 경상(12.5%)지역이 가장 낮은 항체수준을 나타냈다. 연령증가에 따른 항체보유율은 4세 이상이 25%(3/12), 2~4세가 21.6%(11/51), 1~2세가 22.4%(19/87), 1세미만에서 19.4%(11/62)으로 연령별로는 유의성있는 차이가 관찰되지 않았다. 검사대상 야외고양이 중 지역별로 165두에 대하여 한타바이러스와 scrub typhus, murine typhus와 spotted fever group rickettsia 등 3종의 리켓치아에 대한 간접형광항체법으로 검사한 결과 다른 질병의 감염 여부와 관계없이 혈청내에서 항체 양성소견이 관찰되지 않아 현재까지 국내의 고양이들은 이들 질병에 감염이 이루어지지 않은 것으로 판단되었다. This study was performed to obtain the recent information of sero-prevalence against zoonotic diseases including toxoplasmosis, hantanvirus infection, scrub tyhpus, murine typhus, and spotted fever group, transmitted by cats. Serum, samples of cats were collected from five regions in Korea from November 1995 to Octorber 1997. Basic anatomic and pathophysiologic conditions of all cats collected were recorded. Sera were screened by indirect immunoflurescent antibody assay for the presence of specific antibodies against Rickettsia tsutsugamushi, R. typhi and R. sibirica, and hantavirus. For Toxoplasma gondii, there was used by latex aggultination test. Seropositives against T. gondii in 212 stray cats from SeoulㆍKyounggi (47), Kangwon (45), Choungchong (40), Cholla (40), and Kyoungsang (40) were 20.7% (44 cases). Seropositive antibody titers tested were classified as 38.6% in 1:32~256, 31.8% in 1:512~2,048, and 29.5% in 1:4,096~32,768. By sex, male(22.3%) showed higher in seropositives than female (19.3%). No seropositives to hantavirus, Rickettsia tsutsugamushi, R. typhi and R. sibirica in 165 stray cats were detected. Stray cats in Korea were fortunately not invaded by zoonotic causative agents including hantavirus and main zootic rickettsial pathogens.

Breeding of High Quality Hydrid Cultivars of Korean Melon (Cucumis melo L.) with Tender Rind

Eung Kyoo Choi,Un Soon Hwang,Byung-Soo Kim,Hong Jib Choi,Jong-Do Chung,Su Hwan Oh 한국원예학회 2019 한국원예학회 학술발표요지 Vol.2019 No.5

Mulberry heart disease의 병리학적 관찰

정운익,김홍집,은길수,Chung, Un-ik,Kim, Hong-jib,Eun, Gil-soo 대한수의학회 1997 大韓獸醫學會誌 Vol.37 No.3

Mulberry heart disease was associated with vitamin E and selenium deficiency of pigs. Anatomical findings of this disease were hydropericadium, extensive patchy hemorrhage of epicardium, endocardium, and discoloration of dark red color of myocardium. In histological findings were characterized by acute myocardial degeneration, extensive hemorrhage, fibrinoid degeneration of arterioles, PAS positive material deposition of arterioles and capillary thrombosis. In affected herds, feed and serum tocopherol and selenium concentration were less than normal values.

제5요추-제 1 천추간 외상성 전측방 탈구 - 1례 보고 -

김용민,유문집,정필현,차응남,강석,안영언,오형호 대한골절학회 1993 대한골절학회지 Vol.6 No.2

Among the various injuries of spine, dislocation of L5-S1 is very rare, because this kind of injury is caused by rare and specific mechanism, probably. About twenty cases of lumbosacral dislocation were reported in other countries. Only two cases of posterior dislocation and one case of anterior dislocation were reported in Korea. In spite of its rarity, it is very important that this kind of injury may be accompanied with considerable neurologic deficit. In August 1991, we experienced one case of traumatic anterolateral dislocation of L5-S1 , accompanied by paraparesis. Emergency manual reduction resulted in excellently reduced state radiologically, but initiai neurologic deficit improved minimally. Secondary open discectomy and posterior stabilization using Graf instrument were performed. After one year and 9 months' follow-up, the patient complains no low back pain, reveals no radioiogic instability. Most initial neurologic deficits improved greatly, however, mild steppage gait on left side due to weakened tibialis anterior power remained.

닭의 괴사성 장염에 대한 병리학적 연구

김홍집,강문일,정운익,Kim, Hong-jib,Kang, Mun-il,Chung, Un-ik 대한수의학회 1997 大韓獸醫學會誌 Vol.37 No.1

From January of 1991 to December of 1992, 42 chickens collected from 21 poultry farms and also diagnosed as necrotic enteritis(NE) was examined clinical signs, gross and histopathological findings. Main clinical signs were characterized by decreased appetite, mild to severe depression, reductance to move, ruffled feathers, greenish to yellow-browinish diarrhea sometimes including blood. As progressed, diseased chickens showed feces mixed with necrotic debris which detached from the intestinal mucosa and mostly resulted in the death. In chronic cases, there were dirty feathers around cloaca due to diarrhea and notably retarded growth. Principle gross lesions were usually confined to the jejunum and ileum, especially toward the lower part of Meckel's diverticulum. The part of small intestine was frequently distended with gas, and also showed mucosal congestion and hemorrhages with varying degrees. Sometimes, the intestinal mucosa was thickened, and also covered with fibronecrotic psuedomembrane. In addition, there were focal necrosis and severely multifocal ulcreation in the mucosa of small intestine. Major histopathological findings included villous necrosis and erosion of the small intestine covering with lots of bacterial colonies, inflammatory cell infiltration in the lamina propria, and dilatation and hyperplasia of crypts. Luminal exudate contained bacterial colonies, fibrin, erythrocytes, and desquamated epithelium. Thirteen(61.9%) out of 21 NE-occurring farms were complicated with intestinal coccidiosis.

닭의 괴사성 장염 및 건강 계군에서 분리한 Clostridium perfringens의 신속동정 및 독소형 분석

김홍집,강문일,정운익,Kim, Hong-jib,Kang, Mun-il,Chung, Un-ik 대한수의학회 1997 大韓獸醫學會誌 Vol.37 No.1

About Clostridium perfringens causing clinically necrotic enteritis or isolated from the intestinal contens of healthy chicken, We examined the usefulness of a rapid identification method by gas-liquid chromatography as well as the types of toxins. For this study, there were used 169 chickens including 116 broilers, 27 layers and 26 breeders which collected from 9 healty flock and 21 diseased flock showing necrotic enteritis. Among them, Cl perfringens was isolated from 30 chickens(17.8%) including 7 breeders(26.9%), 5 layers(18.5%) and 18 broilers(15.5%). Isolation of Cl perfringens was mainly from ceca (100%) and followed by small intestines(70.0%) and livers(16.7%), respectively. Average concentration of the pathogen in intestinal contents was $10^{3.8}CFU/g$ in cases occuring necrotic enteritis and on the contrary $10^{3.8}CFU/g$ in healthy cases. All isolates tested showed the same characterstics in biochemical tests compared to those in standard strain. Analysis of gas-liquid chromatography to volatile fatty acids produced by Cl perfringens in PYG broth showed the typical peaks of acetic and butyric acids compatible with the standard chromogram and was confirmed as a effective and reliable tool for rapid identification of the bacteria. Toxin types of 30 strains were mostly classified in A type(26 isolates) and the rest in C type(2 isolates) and unidentifed type(2 isolates). All the isolates were highly susceptible to amphicillin, amoxicillin and cephalothin.

닭의 장염발생 조사

김홍집,강문일,정운익,Kim, Hong-jib,Kang, Mun-il,Chung, Un-ik 대한수의학회 1996 大韓獸醫學會誌 Vol.36 No.4

The purpose of the survey was to understand the field situation on the occurrence of enteric diseases in poultry farms in Korea. During the period from January of 1991 to December, 1992, 279(35.8%) out of 779 farms surveyed experienced the cases of enteritis in their chickens. The farms with diarrheal problems consisted of 157(45.1%) of 348 broiler flock, 28(32.6%) of 86 breeder flock, and 94(27.2%) of 345 layer flock. The main diseases causing enteritis were frequently appeared as infectious bursal disease(27.3%), colibacillosis(22.6%), and coccidiosis(8.6%). Necrotic enteritis(NE) in chicken occurred in 21 farms(2.7%) among 779 farms examined. The outbreaks of NE were divided 4.7% in breeders, 4.0% in broilers, and 0.9% in layers, respectively. NE occurred mainly in the age(71.4%) of 20~30 days and the mortality was varying from 1.4% to 10.0% for broilers, 3.0% for layers and 0.8% for breeders. Seasonal prevalence of NE showed the highest as 52.4% in summer and followed by 33.3% in autumn, 9.5% in spring and 4.5% in winter.

Trends in Incidence and Treatment of Herniated Lumbar Disc in Republic of Korea : A Nationwide Database Study

Jung, Jong-myung,Lee, Si Un,Hyun, Seung-Jae,Kim, Ki-Jeong,Jahng, Tae-Ahn,Oh, Chang Wan,Kim, Hyun-Jib The Korean Neurosurgical Society 2020 Journal of Korean neurosurgical society Vol.63 No.1

Objective : This study aimed to determine the incidence and analyze trends of the herniated lumbar disc (HLD) based on a national database in the Republic of Korea (ROK) from January 2008 to December 2016. Methods : This study was a retrospective analysis of data obtained from the national health-claim database provided by the National Health Insurance Service for 2008-2016 using the International Classification of Diseases. The crude incidence and age-standardized incidence of HLD were calculated, and additional analysis was conducted according to age and sex. Changes in trends in treatment methods and some treatments were analyzed using the Korean Classification of Diseases procedure codes. Results : The number of patients diagnosed with HLD was 472245 in 2008 and increased to 537577 in 2012; however, it decreased to 478697 in 2016. The pattern of crude incidence and the standardized incidence were also similar. Overall, the incidence of HLD increased annually for the 30s, 40s, 50s, and 70s until 2012 and then decreased. However, the incidence of HLD for the 80s continued to increase. The crude incidence of HLD in female patients exceeded that of male patients in their middle age (30s or 40s) and was 1.5-1.6 times higher than in male patients in their 60s. The total number of open discectomy (OD) increased from 71598 in 2008 to 93942 in 2012 and then decreased to 85846 in 2016. The rate of younger patients (the 20s, 30s, and 40s) who underwent OD was decreased, and the rate of younger patients who underwent percutaneous endoscopic lumbar discectomy was increased. However, the rate of older patients (the 70s and 80s) who underwent OD was continuously increased. Conclusion : This nationwide data on HLD from 2008 to 2016 in the ROK demonstrated that the crude incidence and the standardized incidence increased until 2012 and then decreased. The annual crude incidence was different according to age and sex. These findings may be considered when deciding future health policy, especially in countries with a similar national health insurance system (or with plans to adopt).

Infectious bursal disease virus 감염이 닭 괴사성 장염의 병원성에 미치는 영향

김홍집,강문일,정운익,Kim, Hong-jib,Kang, Mun-il,Chung, Un-ik 대한수의학회 1996 大韓獸醫學會誌 Vol.36 No.4

For understanding the role of infectious bursal disease virus(IBDV) to the pathogenesis of necrotic enteritis due to Clostridium perfringens(CP), all 15 day-old chickens used were divided as the following groups; A and E group with the feeding of feed contaminated with CP, B group with oral adminstration of IBDV($50{\mu}l/head$, $10^{3.4}EID_{50}$ of $P_4$ strain) and simultaneously feeding of feed contaminated with CP, C group treated with IBDV alone, F group with the feeding of feed contaminated with CP at 3 weeks after oral inoculation of IBDV, D and G group with the feeding of normal feed as controls. In mortality, B group(30%) was not a difference compared to A group(20%)(p>0.05), but in the pathological lesions the former was more severe degree than the latter. The mortality of F group(70%) was a significant difference to those of A, B or E group (20%)(p<0.01). Also, showed much F group more marked lesions than A, B or E group. In the chickens occurred the death during the study, mean concentration of CP was reached at $10^8{\sim}10^9CFU/g$ in the intestinal contents. B group showed higher mortality and more severe pathological changes than A and E group. Consequently, the results in the study were confirmed that the IBDV could be a role as a enhancing factor in pathogenesis of necrotic enteritis due to CP under the field condition.