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Acute Gastrointestinal Bleeding in COVID-19 Patients: A Systematic Review and Meta-Analysis
Umair Iqbal,Hafsa Anwar,Hafiz Umair Siddiqui,Muhammad Ali Khan,Faisal Kamal,Bradley D. Confer,Harshit S. Khara 대한소화기내시경학회 2021 Clinical Endoscopy Vol.54 No.4
Background/Aims: More than 100 million people to date have been affected by the coronavirus disease-2019 (COVID-19)pandemic. Patients with COVID-19 have a higher risk of bleeding complications. We performed a systematic review and metaanalysisto evaluate the outcomes of COVID-19 patients with signs and symptoms of acute gastrointestinal bleeding (GIB). Methods: A systematic literature search was carried out for articles published until until November 11, 2020, in the Embase,MEDLINE, Web of Science, and Cochrane Library databases. We included studies on COVID-19 patients with signs and symptomsof GIB. Results: Our search yielded 49 studies, of which eight with a collective 127 patients (86 males and 41 females) met our inclusioncriteria. Conservative management alone was performed in 59% of the patients, endoscopic evaluation in 31.5%, and interventionalradiology (IR) embolization in 11%. Peptic ulcer disease was the most common endoscopic finding, diagnosed in 47.5% of thepatients. Pooled overall mortality was 19.1% (95% confidence interval [CI]; 12.7%-27.6%) and pooled mortality secondary to GIBwas 3.5% (95% CI; 1.3%–9.1%). The pooled risk of rebleeding was 11.3% (95% CI; 6.8%–18.4%). Conclusions: The majority of COVID-19 patients with GIB responded to conservative management, with a low mortalityrate associated with GIB and the risk of rebleeding. Thus, we suggest limiting endoscopic and IR interventions to those withhemodynamic instability and those for whom conservative management was unsuccessful.
A Review of Large-Scale Hydropower Project in Public Sector of Pakistan
Umair, Muhammad,Choudhary, Muhammad Abbas,Jahanzaib, Mirza Korea Institute of Construction Engineering and Ma 2014 Journal of construction engineering and project ma Vol.4 No.4
Client organization inadequate project planning before awarding the contract and insufficient monitoring and control system among the parties involved create severe problems. Ultimately, large-scale projects go beyond the expected cost and time control limits. This paper discusses the major issues involved with a large-scale Hydropower Project in Pakistan Public Sector environment. The latest approved Baseline Plan of project was reviewed and analyzed using Variance Analysis and Trend Analysis techniques in Primavera project management software to assess the efforts made of the parties involved. It was found that Project is 202% Cost overrun and 25% time delays from original contract award. After analysis of baseline plan and quantification of various variance issues in impacted activities, the questionnaire survey was conducted to identify the impact of causative factors. There were almost 17 most significant causative factors identified among 60 identified factors and responsibilities are assigned accordingly. At the end recommendations are made for strategic decisions as lessons learned during project evaluation.
Umair, Zobia,Kumar, Vijay,Goutam, Ravi Shankar,Kumar, Shiv,Lee, Unjoo,Kim, Jaebong Korean Society for Molecular and Cellular Biology 2021 Molecules and cells Vol.44 No.10
Spemann organizer is a center of dorsal mesoderm and itself retains the mesoderm character, but it has a stimulatory role for neighboring ectoderm cells in becoming neuroectoderm in gastrula embryos. Goosecoid (Gsc) overexpression in ventral region promotes secondary axis formation including neural tissues, but the role of gsc in neural specification could be indirect. We examined the neural inhibitory and stimulatory roles of gsc in the same cell and neighboring cells contexts. In the animal cap explant system, Gsc overexpression inhibited expression of neural specific genes including foxd4l1.1, zic3, ncam, and neurod. Genome-wide chromatin immunoprecipitation sequencing (ChIP-seq) and promoter analysis of early neural genes of foxd4l1.1 and zic3 were performed to show that the neural inhibitory mode of gsc was direct. Site-directed mutagenesis and serially deleted construct studies of foxd4l1.1 promoter revealed that Gsc directly binds within the foxd4l1.1 promoter to repress its expression. Conjugation assay of animal cap explants was also performed to demonstrate an indirect neural stimulatory role for gsc. The genes for secretory molecules, Chordin and Noggin, were up-regulated in gsc injected cells with the neural fate only achieved in gsc uninjected neighboring cells. These experiments suggested that gsc regulates neuroectoderm formation negatively when expressed in the same cell and positively in neighboring cells via soluble factors. One is a direct suppressive circuit of neural genes in gsc expressing mesoderm cells and the other is an indirect stimulatory circuit for neurogenesis in neighboring ectoderm cells via secreted BMP antagonizers.
A Review of Structural Testing Methods for ASIC based AI Accelerators
Umair, Saeed,Irfan Ali, Tunio,Majid, Hussain,Fayaz Ahmed, Memon,Ayaz Ahmed, Hoshu,Ghulam, Hussain International Journal of Computer ScienceNetwork S 2023 International journal of computer science and netw Vol.23 No.1
Implementing conventional DFT solution for arrays of DNN accelerators having large number of processing elements (PEs), without considering architectural characteristics of PEs may incur overwhelming test overheads. Recent DFT based techniques have utilized the homogeneity and dataflow of arrays at PE-level and Core-level for obtaining reduction in; test pattern volume, test time, test power and ATPG runtime. This paper reviews these contemporary test solutions for ASIC based DNN accelerators. Mainly, the proposed test architectures, pattern application method with their objectives are reviewed. It is observed that exploitation of architectural characteristic such as homogeneity and dataflow of PEs/ arrays results in reduced test overheads.
Umair Ali Toor,신현아,김동진 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.71 No.-
Efficiency of phosphorus recovery from polyaluminum chloride sludge is determined by chemicalinteractions between Al and P. Chemical structure of Al–P complex and their binding mechanisms in thePAC sludge were investigated with spectroscopy and chemical fractionation. More than 98% of the P wasbound with Al, out of which 70% was strongly bound. The ATR-FTIR analysis indicates that the majority ofthe P formed inner sphere complex with Al through ligand exchange. The availability of highly protonatedsurface for P sorption at low pH also supports the formation of Al–P outer sphere complex.
( Umair Ahmed Siddiqui ),전은경 ( Eunkyung Jeon ) 한국의류산업학회 2017 한국의류산업학회지 Vol.19 No.1
To predict and foster professional research issues for the present and future, it is important to understand the stream of research trends. This study is to provide information of research trend through analysis of quantitative variables in 1,374 articles from the first issue to the present(2015) of the Fashion and Textiles Research Journal. As a result, in the former periods, articles in the field of textile science & technology and fashion design & historical concerns, and articles that used experiments and others as a research method were dominant; in the latter periods, articles in the field of fashion marketing & merchandising and apparel production & technology, and articles that used survey as a research method were dominant. According to each detailed research field and method, there were significant differences in the number of pages, authors and references of articles. In addition, it was found that the number of pages and the number of references increased sharply in the latter period, indicating that the contents of the papers were more detailed and faithful to references of other studies. Through the analysis of this study, it was found that Fashion and Textiles Research Journal published a variety of articles in the academic fields. The research information analyzed in this study will contribute to the future design for the research as well as the academic societies.