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      • 테르펜과 1,2-디메틸싸이클로펜텐의 기체상 오존화반응

        윤의중,구본석,정인수,정인찬,이영훈,신혜숙 한서대학교 산학협력연구원 부설 환경연구소 2000 환경연구소 논문집 Vol.3 No.-

        Gas phase Ozonolyses have been examined with particular emphasis on the question whether are produced. The following results were obtained. 1) In contrast to previous reports, Ozonolyses of the terpense β-pinene and sabinene provided the corresponding ozonides as minor products. Major products were the corresponding ketones, respectively. In addition, β-pinene afforded the lactones, while sabinene gave the lactones. 2) Ozonolyses of 1, 2-dimethylcyclopentene provided the corresponding ozonide as a minor and diketone as the major product, along with small proportions, each, of nine additional products. 3) Ozone treatment of diketone provided small amounts of Ozonide in a hitherto unprecedented reaction of diketiones with ozone.

      • KCI등재

        전치부의 발육 결함 및 교정 후 탈회 병소의 심미적 개선을 위한 resin infiItration

        김은영,안울진,김신,정태성 大韓小兒齒科學會 2010 大韓小兒齒科學會誌 Vol.37 No.2

        어린이 영구전치의 법랑칠 발육 결함이나 고정성 장치에 의한 교정치료 후 탈회 병소는 흔히 심미적 문제를 유발한다. 본 연구는 상악 전치부에 위 원인에 의한 탈회로 인하여 백반양 병소를 보이는 21명 어린이의 38개 치아를 대상으로, 최근 비침습적인 방법으로 소개된 resin infiltration 기법을 적용하고, 병소의 색조의 임상적 개선 효과를 비교, 분석하여 다음과 같은 결과를 얻었다. 1. 1주 후 색조가 개선된 병소는 발육 결함 병소의 25%, 교정 탈회 병소의 61%로 나타났다. 2. 발육 결함 병소의 40%, 교정치료 후 탈회 병소의 6%에서는 시술 전후의 색조변화를 관찰할 수 없었다. 3. 법랑질 발육결함 병소에서는 시술 직후 보다 1주 후에 더 많은 색조 변화를 관찰할 수 있었다. 결과적으로 일부 증례에서는 색조의 극적인 개선이 관찰되었으나, 또 일부 증례에서는 변화가 거의 나타나지 않았는데, 이는 병소 깊이의 차이에 기인한 것으로 사료되었다. The prevalence of developmental defects of enamel and lesios by post-orthodontic decalcification has been reported with increasing frequency. Even though there have been increasing interests and clinical challenges in esthetic improvement of these lesions, few of studies were reported for using non-invasive approach which is a very significant matter for child and young adults. This study was conducted to assess clinical effect on the improvement in color of these lesions via resin infiltration method developed as minimum invasive technique for white spot. For the 38 maxillary anterior teeth with calcification problem. the changes in color between before- and after- infiltration treatment, were evaluated and summarized as following. 1. A week after infiltration, 25% of developmental defects and 61% of decalcification lesions were improved in color as the value of ΔE below 3.7. 2. 40% of the developmental defects and 6% of decalcification lesions showed no significant change. 3. The developmental defects showed more remarkable changes in color 1 week after infiltration rather than immediately after the treatment. From our study results, it is considered that the amount of color improvement depended on the depth of lesion. In other words, for the lesion having more depth than the depth infiltrant resin can penetrate into, infiltration treatment showed no significant effect. Therefore, for clinical indication of resin infiltration treatment, further research on precise measurement technique of lesion depth is strongly required.

      • KCI등재

        초등학생의 Molar Incisor Hypomineralization 유병률과 제1대구치 치아우식증 및 수복상태 조사

        신종현,안울진,김신,정태성 大韓小兒齒科學會 2010 大韓小兒齒科學會誌 Vol.37 No.2

        Molar Incisor Hypomineralization(MIH) have recently gained intensive research interests and various clinical trials. Most prevalence, etiology, treatment studies in MIH were carried out in the European countries, and data from the Korean were seldom. This study aimed to investigate the prevalence of MIH and the status of dental caries and treatment on the first permanent molars in primary school children. For this study, 1.344 primary school students in Busan and Ulsan cities were examined directly the permanent incisors and first molars. The results of the survey were as follows: 81 MIH cases were identified among 1.344 cases. The prevalence of MIH in this group of children was 6.0%. Children with MIH showed a significantly higher DMFT value for permanent teeth than children without MIH. The mean number of decayed, missed, and filled in 1st permanent molars(DMFT index) was 1.17. The rate of children with restoration on 1st permanent molar was 13.6% and the sequence of restoration materials was as follows: composite resin, amalgam, gold inlay. Molar Incisor Hypomineralization(MIH)에 관하여 최근 많은 연구적 관심이 집중되고 여러 임상적 대처방법들이 제시되고 있다. 이미 세계적으로는 MIH의 빈도, 병인, 치료 등에 관한 많은 연구보고가 있었으나, 우리나라에서는 이에 대한 관심이 아직 미미한 것으로 사료된다. 본 연구는 초등학생의 MIH 유병률과 제1대구치 우식 및 치료 실태에 대하여 조사할 목적으로 시도되었다. 부산 및 울산광역시에 거주하는 1,344명의 초등학생을 대상으로, 상하 제1대구치와 전치부를 직접 시진하여, MIH 유병률, 제1대구치 우식경험지수와 치료 상태를 조사하여 다음과 같은 결과를 얻었다. 총 1,344명 의 조사 대상 중 81명에서 MIH가 나타나, 유병률은 6.0%를 보였으며, MIH에 이환왼 어린이의 제1대구치 우식경험지수는 비이환군에 비해 통계적으로 유의하게 높았다(P<0.05) 한편, 제1대구치 우식경험지수는 1.17개로 나타났다. 조사 대상 제1대구치의 13.6%가 수복되어 있었고, 수복재 별로는 복합 레진, 아말감, gold inlay의 순이었다.

      • Zigbee sensor 모듈에 적용 가능한 소형 PCB 안테나의 최적 설계 기법 연구

        이영순,김의중,이태훈,정훈희 금오공과대학교 2006 論文集 Vol.27 No.-

        본 논문에서는 소형 Zigbee sensor 모듈에 적용하기에 적합한 모듈 일체형 안테나의 최적 설계시법을 제기하고자 한다. Zigbee sensor 모듈에서 사용되는 2.45GHz 대역에 적합한 모듈 일체형 안테나를 meander slit 구조를 이용하여 최적설계 과정을 보이고, 최적화된 안테나의 설계 결과를 보였다. 그리고 기존 chip 안테나의 성능 비교를 위해 최대 동작거리 및 방사출력을 비교한 결과를 제시 하였다.

      • 간외담관 폐쇄에서의 초음파소견 : 담관벽 경계소실의 중요성 Significance of Decreased Echotexture of Bile Duct Wall-Interface

        신현준,손은주,이창희,최영칠,전혜정,박정희,이태의 건국대학교 의과학연구소 2002 건국의과학학술지 Vol.12 No.-

        Ultrasound is very useful in evaluation of obstructive jaundice. We retrospectively evaluated the useful findings of ultrasonography in differentiating benign extrahepatic duct obstruction from malignant diseases. Among the 36 patients, 25 patients were benign extrahepatic obstruction and 11 patients were malignant obstruction. The shapes of extrahepatic dilatation were classified into fustiform, meniscus, and abrupt cut off by bowel gas. The diameter, length, and bile duct wall-interface were compared between benign and malignant groups and serum bilirubin and alkaline phosphatase were also compared between two groups retrospectively. The results were as follows. The most common form of extrahepatic dilatation was meniscus(10 of 26 patients, 38%) in benign obstruction, and fusiform(8 of 11 patients, 73%) in malignant obstruction. No significant difference was noted in diameter, length, serum bilirubin, and alkaline phosphatase between benign and malignant groups. Only one case showed decreased bile duct wall-interface in benign obstruction, but loss or decrease of bile duct wall-interface were 8 patients in malignant obstruction. The combined findings of fusiform dilatation and loss of bile duct wall-interface in ultrasonography will be helpful in differential diagnosis of malignant extrahepatic bile obstruction from benign conditions.

      • SCOPUSKCI등재

        Effect of Drug Loading on the Physicochemical Properties and Stability of Cationic Lipid-based Plasmid DNA Complexes

        Jeong, Ui-Hyeon,Jung, Ji-Hye,Davaa, Enkhzaya,Park, Se-Jin,Myung, Chang-Seon,Park, Jeong-Sook The Korean Society of Pharmaceutical Sciences and 2009 Journal of Pharmaceutical Investigation Vol.39 No.5

        Recently, co-delivery of drug and gene has been attempted for higher therapeutic effects of anticancer agents. In this study, cationic liposomes were prepared using 1,2-dioleoyl-3-trimethylammoniopropane (DOTAP) as a cationic lipid to investigate the effect of drug loading on the physicochemical characteristics of cationic liposomes/DNA complexes. The complex formation between cationic liposomes and negatively charged plasmid DNA was confirmed and the protection from DNase was observed. Particle size of complexes was reduced not by drug loading, but by the increased ratio of cationic lipid to plasmid DNA. Meanwhile, zeta potential of complex was increased by the addition of cationic liposomes to complexes and the effect of drug loading on the zeta potential was not much higher than on particle size. Gel retardation of complexes was indicated when the complexation weight ratios of cationic lipid to plasmid DNA were higher than 24:1 for drug free complexes and 20:1 for drug loaded ones, respectively. Agarose gel retardation showed the similar complexation between plasmid DNA and drug free liposomes or drug loaded liposomes. Both complexes protected plasmid DNA from DNase independent of complexation temperature. From the results, drug loading may affect not the complex formation of cationic liposomes and plasmid DNA, but the particle size of complex.

      • KCI등재

        Effects of Sciatic Nerve Mobilization on Pain and Lower Back Isometric Muscle Strength in Female Patients in their 40s with Lumbar Radiculopathy

        Ui Cheol Jeong,Hee Kyung Kim,Hyo Jin Yoo,Cheol Yong Kim 국제물리치료학회 2017 Journal of International Academy of Physical Ther Vol.8 No.1

        The Purpose of this study was to determine the effects of sciatic nerve mobilization on pain and lower back muscle strength in female patients in their 40s who have been diagnosed with lumbar radiculopathy. Using a simple blinded method, 20 female patients with neuropathy in the nerve segments between L4-S1 were randomly divided into one group (n=10) that would undergo sciatic nerve mobilization, and another group (n=10) that would perform lower back segment stabilization exercises. The two groups attended 3 sessions per week, with each session taking 30 minutes, for a duration of 4 weeks. In the preliminary examinations, the pain index as well as the isometric muscle strength of the lower back extensor and flexor muscles were measured. After the passing of 4 weeks. The same method of measurement was used for the concluding examinations. Comparison of the pain indices in the two groups revealed that they both experienced a statistically significant decrease, and further inspection revealed that the there was a more substantial difference in the sciatic nerve mobilization group. Results of comparing changes in the Isometric Muscle Strength lower back muscle and bending muscle by group, In comparison between groups, the isometric strength of the lower back extensor showed a more significant difference in the sciatic nerve mobilization group (p <.05). Conclulsion, it can be inferred that application of sciatic nerve mobilization has a positive effect on the pain index and isometric muscle strength of the lower back in female patients with lumbar radiculopathy in their 40s.

      • KCI등재

        Anti-diabetic effects of water extract from the dietary mushroom Neolentinus lepideus in type 2 diabetic db/db mice

        Ui jeong Yun,Hyesun Jung,Kye Won Park,Ki-Moon Park 한국버섯학회 2017 한국버섯학회지 Vol.15 No.3

        The objective of this study was to determine the anti-diabetic effect of the water extract of Neolentinus lepideus in a diabetic mouse model. Seven-week-old C57BL/KsJ-db/db mice were fed either a control diet (CD) or diet supplemented with 1% or 5% of N. lepideus water extract (NLWE1 or NLWE5) for 10 weeks. Oral administration of NLWE significantly decreased the body weight gain compared to that of CD-fed group. Mice in the NLWE group had significantly lower levels of fasting serum glucose, fatty acids, and low-density lipoprotein cholesterol compared to those in the control group. These effects were accompanied by reduced fatty liver and improved glucose tolerance in the NLWE group. Taken together, these results suggest that N. lepideus might have potential as a dietary supplement to control diabetes.

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