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      • KCI등재

        Risk of Diabetic Retinopathy between Sodium-Glucose Cotransporter-2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists

        Tzu-Yi Lin,Eugene Yu-Chuan Kang,Shih-Chieh Shao,Edward Chia-Cheng Lai,Sunir J. Garg,Kuan-Jen Chen,Je-Ho Kang,Wei-Chi Wu,Chi-Chun Lai,Yih-Shiou Hwang 대한당뇨병학회 2023 Diabetes and Metabolism Journal Vol.47 No.3

        Background: To compare risk of diabetic retinopathy (DR) between patients taking sodium-glucose cotransporter-2 inhibitors (SGLT2is) and those taking glucagon-like peptide-1 receptor agonists (GLP1-RAs) in routine care.Methods: This retrospective cohort study emulating a target trial included patient data from the multi-institutional Chang Gung Research Database in Taiwan. Totally, 33,021 patients with type 2 diabetes mellitus using SGLT2is and GLP1-RAs between 2016 and 2019 were identified. 3,249 patients were excluded due to missing demographics, age <40 years, prior use of any study drug, a diagnosis of retinal disorders, a history of receiving vitreoretinal procedure, no baseline glycosylated hemoglobin, or no follow-up data. Baseline characteristics were balanced using inverse probability of treatment weighting with propensity scores. DR diagnoses and vitreoretinal interventions served as the primary outcomes. Occurrence of proliferative DR and DR receiving vitreoretinal interventions were regarded as vision-threatening DR.Results: There were 21,491 SGLT2i and 1,887 GLP1-RA users included for the analysis. Patients receiving SGLT2is and GLP-1 RAs exhibited comparable rate of any DR (subdistribution hazard ratio [SHR], 0.90; 95% confidence interval [CI], 0.79 to 1.03), whereas the rate of proliferative DR (SHR, 0.53; 95% CI, 0.42 to 0.68) was significantly lower in the SGLT2i group. Also, SGLT2i users showed significantly reduced risk of composite surgical outcome (SHR, 0.58; 95% CI, 0.48 to 0.70).Conclusion: Compared to those taking GLP1-RAs, patients receiving SGLT2is had a lower risk of proliferative DR and vitreoretinal interventions, although the rate of any DR was comparable between the SGLT2i and GLP1-RA groups. Thus, SGLT2is may be associated with a lower risk of vision-threatening DR but not DR development.

      • KCI등재

        Prioritization of Sleep: Discrepancies Between Attitude and Practice

        Ya-Chuan Huang,Tzu-Ting Lin,Chien-Ming Yang 대한수면연구학회 2023 Journal of sleep medicine Vol.20 No.3

        Objectives: With the promotion of sleep through education, an increasing recognition of the importance of sleep among the general public has been observed. However, whether this increased recognition affects sleep practices is unknown. To provide direction for future sleep education programs, this study aimed to explore the consistency between people’s prioritization of sleep among their daily life activities and their actual practice when sleep conflicts with other activities.Methods: The study was a cross-sectional online survey with 898 adults (male:female=372:526; age=39.74±10.04 years). The participants were asked to complete an online survey that required them to 1) rate how important sleep was; 2) prioritize daily life activities including sleep, work, family activities, leisure activities, social activities, and exercise; and 3) recall the actions they undertook at the most recent instance when sleep conflicted with each of the other activities.Results: Although 70.7% of the participants prioritized sleep by placing it in their top three daily life activities, only 35.7% and 38.1% chose to go to sleep when it conflicted with work and family activities, respectively. Gender and occupational factors also significantly influenced the discrepancy between sleep attitudes and practices.Conclusions: Our study demonstrated an inconsistency between reporting sleep as a priority in daily life activities and actual behavioral practices when sleep conflicted with other activities. The results suggest that sleep education should not only emphasize the importance of sleep but also provide practical solutions for circumstances when sleep conflicts with other activities.

      • THE EFFECT OF VIRTUAL COMMUNITY CODEPENDENCY ON VIRTUAL COMMUNITY ADDICTION: EXPLORING THE MEDIATION EFFECTS

        Long-Chuan Lu,Ching-Tzu Tsai 글로벌지식마케팅경영학회 2018 Global Marketing Conference Vol.2018 No.07

        Introduction Virtual communities have changed lifestyles and interpersonal relations, creating an internet community culture. They are a primary medium of emotional contact with others. American psychologist estimated that more than 350 million people have Facebook Addiction Disorder (FAD) (Hong et al., 2014; SickFacebook.com, 2010), some kind of virtual community addiction (VCA). An average of 728 million people use Facebook every day, and users spend much time on Facebook (Hong et al., 2014). 80.24% of university students think that Facebook is an important element of social culture (Thompson & Lougheed, 2012). VCA has been explored in psychology in the past. This study adds three psychological dimensions and sense of virtual community when investigating the antecedents of VCA. The results of this study may direct public attention to VCA and help develop guidelines for online marketing and operation of virtual communities. Literature review and hypotheses development Virtual community addiction (VCA) Many people are not aware of addictive in virtual community. While some addictive behaviors are considered mental disorders, an increasing number of studies has found potentially addictive behavior involving computers and the internet (Andreassen et al., 2012), including video game addiction (Fisher, 1994), Internet addiction (Beard, 2005), mobile phone addiction (Choliz, 2010), and online addiction (Griffiths, 2012). The definition of Internet addiction remains controversial. This study defines VCA as a tendency that users forced to use and even can not control not to use for the virtual communities. Virtual community codependency (VCC) Although codependency lacks a clear definition, there are only two perspectives on codependency that are relevant to this study. First, codependency is a learned helplessness, resulting in individuals who cannot create or participate in interpersonal relationships in the future (O’Gorman, 1993). Second, codependency is a pattern of dysfunction in interpersonal relationships. According to the social compensation theory, if people feel insecurity and negative social identity in real life interpersonal networks, they may spend more time using virtual communities as compensation. Therefore, we hypothesize: H1. Virtual community codependency (VCC) positively influences virtual community addiction (VAC). Sense of virtual community (SVC) Blanchard (2007) defined the SVC as members feel membership, a sense of belonging and attachment to the group through electronic communication. Abfalter et al. (2012) defined the SVC as members having a sense of ‘spirit of belonging together’ in a virtual community. Members are interacting more, making them develop close relationships that lead to a stronger bond (Abfalter et al., 2012; Chavis et al., 1986; Obst et al., 2002). Facebook is widely used in the virtual community, regardless of the number and use of the degree has been increasing. Thus, we conclude that high VCC will need individuals to have a desire to derive compensation from the virtual community that cannot be achieved in the real world. If people in this community have similar needs, priorities, and goals, increasing the use of Facebook will lead to an increase in VCA. We propose the following hypothesis: H2. The relationship between the Virtual Community Codependency (VCC) and Virtual Community Addiction (VAC) is mediated by the Sense of Virtual Community (SVC). Behavioral inhibition system (BIS) and behavioral approach system (BAS) Gray (1982) proposed the most widely applied pair of systems controlling behavioral activity, the behavioral inhibition system (BIS) and the behavioral approach system (BAS). These are intrinsic motivation systems in charge of desire and disgust (Carver & White, 1994). They are used to measure the sensitivity of individuals to punishment avoidance and to reward acquisition. When the sensitivity of an individual toward penalty/reward is higher, their response to a stimulus is greater (Linden et al., 2007). Studies also show that Internet addiction and BIS are related (Yen et al, 2009). Thus, we conclude that high VCC will be stimulated by BIS when there is an accident or a novel experience, and negative emotional reactions will seek to be resolved in the virtual world. Hence, Facebook users will to escape from the real environment to the virtual world, so as to addict on the virtual community. This leads to the following hypothesis: H3. The direct relationship between the Virtual Community Codependency (VCC) and Virtual Community Addiction (VAC) is mediated by the Behavioral Inhibition System (BIS). BAS is based on motivations for an individual to pursue and achieve goals. BAS is more active and more sensitive to external reward clues, leading to stimulated sensory seeking behavior (Beauchaine et al., 2001). If the incentive clues appear, individuals who have high BAS are more prone to short positive emotions and approaching behavior individuals with low BAS. Thus, we speculate that high VCC will be stimulated by BAS when there is reward responsiveness or when driven in pursuit of goals in the virtual community. It will also make it more likely to engage in fun seeking in virtual communities. Thus, Facebook users deeply trapped in the virtual environment by BAS stimulation and fail to pull themselves out. Therefore, we hypothesize: H4. The direct relationship between Virtual Community Codependency (VCC) and Virtual Community Addiction (VAC) is mediated by the Behavioral Approach System (BAS). Methodology Survey development and measurement We adapted a number of scales (Abfalter et al., 2012; Andreassen et al., 2012; Carver & White, 1994; Fischer et al., 1991) and compiled a 55 item self-report scale questionnaire. Following the procedure recommended by Churchill (1979), we pre-tested the scale on 30 college students to determine the reliability and validity of the constructs. Based on the feedback, we refined the measures and ensured that all of the questionnaire items were applicable to our research. Finally, 53 valid items were retained in the formal questionnaire. Data collection and sample profile We used a web-based survey to collected data from the Youthwant survey platform in Taiwan. This was a more effective way to search for respondents for this study. The formal questionnaires were free to answer by members of the network platform. The participants were told of the survey’s importance to trigger participant’s interest, and give a 10 bonus points as reward. A total of 224 questionnaires were returned, 3 invalid and 221 effective. Respondents were evenly distributed across various ages between 18 and 50 years. The majority of respondents were female (60.2%) and only about 23.1% were students. Most respondents had completed university education (60.6%). 93.6% had been used Facebook for more than one year, with 63.3% having over four years of membership. 70.6% use Facebook more than once a day and for 82.8%, daily usage is at least a half hour, while 71.0% exceed a half an hour each time they use Facebook. This shows that of all respondents were long-term users. Results The total effects are determined by testing the direct impact of VCC on VCA without the mediator constructs. The results (see Table 1) show a significant relationship between VCC and VCA (β11 = 0.572, p < 0.001), supporting H1 (VCC positively affects VAC). The mediating effect is slight but statistically significant. 0.096 of the indirect effect is the result of the effect of VCC on SVC, which in turn influences VCA. The direct relationship between the VCC and VCA is significant as mediated by the SVC. Thus, H2 was supported. The mediating effect involves testing the direct relationship between the VCC and VCA mediated by the BIS. The results show a significant relationship between VCC and VCA (β13 = 0.488, p<0.001). VCC positively and significantly affects BIS (β12 = 0.493, p < 0.001). The effect of BIS on VCA is also positively significant (β23 = 0.169, p <0.05). This was confirmed by the evaluation of the structural model results. The direct effect is 0.488 (t = 5.661, p < 0.001) and the indirect effect is 0.083 (0.493 ? 0.169= 0.083) which is significant (z = 2.039, p < 0.05) by Sobel test. Thus, the direct relationship between the VCC and VCA is slightly mediated by BIS. H3 was supported. The VAF of the model is 33.70% (0.193 / (0.380 + 0.193) ? 100%). In this situation, a VAF larger than 20% and less than 80% can be characterized as partial mediation (Hair et al., 2014). The ?2 effect size is 0.117, showing that BAS has medium effects on VCA. Thus, H4 was supported. Discussion This study is a step by step quantification of how changes in virtual community codependency (VCC) are related to changes in virtual community addiction (VCA) directly and indirectly through one or more mediators. First, the results show a strong relationship between virtual community codependency (VCC) and virtual community addiction (VCA). Furthermore, we cannot deny that the sense of virtual community (SVC) has a small mediating effect on the direct relationship between virtual community codependency (VCC) and virtual community addiction (VCA). The increased use of Facebook when there is a sense of the ‘spirit of belonging together’ can lead to increased tendency to virtual community addiction (VCA). The results are supported by Fischer et al. (1991) and Hong et al., (2014). Limitations and future research directions There are limitations in this study. First, this study does not have a large sample. Second, with technology advances and use behavior changes, the popularity of virtual communities and dependency is rising. The virtual community addiction scale can only evaluate the current situation. This study investigated the latent variables that determine partial or complete mediation using the AVF of Hair (2014). The judgment of AVF uses rules of thumb and awaits meta-analysis of partial and/or complete mediation in the future. Finally, future research could examine virtual communities in other cultures.

      • CHEAP OR VALUABLE?! THE INTERACTION EFFECTS OF ORIGINAL PRICE AND DISCOUNT PRESENTATION ON SUBOPTIMAL FOOD PURCHASE INTENTIONS

        Hsiu-Hua Chang,Long-Chuan Lu,Tzu-Chiao Kuo 글로벌지식마케팅경영학회 2023 Global Marketing Conference Vol.2023 No.07

        To reduce food waste at the retail and personal consumption stages, discounts are offered in retail channels to encourage consumers to buy goods that are less attractive or close to their expiry dates. While discounts can encourage consumers to accept and purchase suboptimal foods, previous studies find that low prices or price discounts will make consumers produce positive or negative perceptions of product values. Consumers may increase their purchase intentions due to price concessions, but will think that price reductions are caused by quality degradation and thus reduce their purchase intentions. Additionally, the literature rarely explores the interaction between original prices of suboptimal products and discount presentation modes. This study thus contends that the interaction between original prices of goods and discount types will lead to significant differences in consumers' attitudes and purchase behavior toward suboptimal products. For research goals, this study employed a full factorial between‐subjects experiment designed with 2 original prices (High and Low) × 2 discount presentation modes (Discount percentage and Discounted price). An anonymous web-based questionnaire posted on the popular PTT forum and in Facebook and Instagram related communities is used to collect the data, and then a total of 328 valid questionnaires were finally collected. The findings indicate that attitudes and purchase intentions toward suboptimal food with a low original price is significantly higher than that of a high original price. Among the interaction effects, the means of attitudes and purchase intentions on the level of the low original price of suboptimal foods presented by discount percentage are higher the other three types. For the high original prices of suboptimal foods, the means of attitudes and purchase intentions on the level of discounted price are higher than for discount percentage. Based on these findings, this study demonstrates that consumer attitudes and purchase decision-making toward suboptimal foods are shaped by original prices and discount presentation modes. In Asia-Pacific countries such as Taiwan, consumers are price-sensitive but once a food item belongs to the category of suboptimal foods, their perceptions of discounts become different. Consumers’ attitudes toward that food and their willingness to buy may be moderated by the high or low original price of suboptimal food with the levels of discount presentation mode. Thus, based on the analysis and results of this study, we offer fresh findings and make both theoretical and managerial contributions to the related field of suboptimal food marketing and price discounts.

      • KCI등재

        Applying Mindfulness Techniques to the Management of Depressive Tendencies in Women in Taiwan in the Perinatal Period: A Qualitative Study

        Pan Wan-Lin,Gau Meei-Ling,Hsu Tzu-Chuan,Shen Shu-Chiao,Lee Tzu-Ying 한국간호과학회 2022 Asian Nursing Research Vol.16 No.3

        Purpose: Perinatal distress, especially depression, commonly occurs during pregnancy and the first year postpartum, but this medical condition are often undiagnosed and untreated. The present study explored how women with depressive symptoms during the perinatal period who had participated in a mindfulness course applied the training and perceived its effects. Methods: This descriptive qualitative study included 16 women with probable perinatal depression who had participated in an 8-week mindfulness-based childbirth and parenting program during their pregnancy and agreed to be interviewed. One-to-one in-depth interviews were conducted and recorded following the completion of the mindfulness course, approximately 1 month after childbirth. Verbatim transcripts were analyzed using content analysis. Results: We proposed three themes and six subthemes relating to first-time mothers’ experiences during and after the group mindfulness-based intervention: learning to be aware of the body and mind (confronting awareness of physical change, managing negative feelings differently), building positive family relationships (strengthening the motherebaby bond, developing a satisfactory marital partnership), and overcoming ongoing challenges (conquering childbirth pain with confidence, accepting unexpected situations). Three main themes were generated to demonstrate how women experience the effects of mindfulness training. Conclusions: Mindfulness-based interventions helped the participants develop insight into their mood and physical changes and accept their childbirth process. Therefore, mindfulness education programs can be incorporated into prenatal care to enhance the management of the depressive symptoms of perinatal women.

      • Living Experiences of Male Spouses of Patients with Metastatic Cancer in Taiwan

        Lin, Hui-Chen,Lin, Wen-Chuan,Lee, Tzu-Ying,Lin, Hung-Ru Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

        Background: Cancer is the leading cause of death in Taiwan. Spouses are generally the main caregivers of affectyed patients but previous studies have seldom investigated the needs of male spouses of patients with metastatic cancer. Purpose: To explore the lived experiences of such male spouses. Methods: A qualitative design using in-depth interviewswasconducted with male spouses of patients with metastatic cancer being treated at the oncology outpatient department in a teaching hospital in northern Taiwan. Results: Nine participants aged 31-78 were interviewed. Content analysis of the interviews revealed five themes: suffering and struggling, difficulty in focusing on communication and interaction, shouldering responsibility, cherishing the love between husband and wife, and enabling each other to live better. This study demonstrated how male spousse experienced physical and psychological suffering when their wives suffered from metastatic cancer. They had to bear the pain of their wife's suffering, and also had to shoulder the responsibility for everything. All their efforts were put towards enabling each other to live a better life. They cherished the rest of the time they could spend with their wives, even though they had to live a hard life. As the male spouses of patients with metastatic cancer, the participants exhibited both the masculinity of men and the ability to express care and tenderness. Conclusions: The results showed that male spouses need more attention in terms of communication and bearing with suffering. Health care professionals should more actively understand the needs and provide assistance when facing the male spouse of patients with cancer, so as make sure that they possess the ability to take care of their wives. Health care professionals should also assist and properly act as a bridge of communication between husbands and wives.

      • KCI등재

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