The Effect of Benzene on the Activity of Adenosine Deaminase in Tissues of Rats

Turhan, Ali,Dere, Egemen Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.3

Swiss Albino (Rat rattus norvegicus) rats were intraperitoneally injected with a 100 mg $kg^{-1}$ dosage of benzene, a toxic and carcinogenic agent widely used for industrial purposes. Changes in the adenosine deaminase (ADA) activity in the liver, kidney and serum of rats were investigated at 0, 2, 4, 8, 16, 32 and 64 h following injection. Serum physiological was administered to each control group. Enzyme activities were measured spectrophotometrically. Our purpose was to further investigations of some diseases caused by benzene, and present evidence of variations in the activity of ADA enzyme effected by benzene. While benzene caused significant inhibitions in ADA activity in the liver at 16 and 32 h and at 0.05 probability level, no significant inhibition or activation occurred at other test periods (hours). ADA activity did not present any significant variation in the kidneys. It was observed that ADA activity displayed similar patterns in the control groups. Comparisons of ADA activities in the two groups showed a statistically significant decrease between $4^{th}$ and $64^{th}$ hours (p< 0.05), demonstrating a direct correlation between benzene and its effects on ADA enzymes.

Evaluation of the Nutritional and Storage Quality of Meatballs Formulated with Bee Pollen

Turhan, Sadettin,Yazici, Fehmi,Saricaoglu, Furkan Turker,Mortas, Mustafa,Genccelep, Huseyin Korean Society for Food Science of Animal Resource 2014 한국축산식품학회지 Vol.34 No.4

In this study, the nutritional and storage quality of meatballs formulated with different levels (0, 1.5, 3.0, 4.5 and 6.0%) of bee pollen were investigated during storage at $41^{\circ}C$ for 9 d. Protein content of meatballs increased, while moisture content decreased with increased pollen. The addition of pollen improved cooking loss but decreased the redness (Hunter a value) and sensory scores. Textural parameters (hardness, springsness, gumminess, and chewiness) were affected by pollen addition and the hardness and gumminess values of meatballs decreased as the pollen content increased. While C18:0 content of meatballs slightly decreased with pollen addition, C18:2n-6c, C18:3n-3, C20:5n-3, and PUFA contents increased. The PUFA/saturated fatty acids (P/S) ratio increased from 0.05 in the control to 0.09 in meatballs with 6.0% pollen. The n-6/n-3 ratio decreased from 11.84 in the control to 3.65 in the meatballs with 6.0% pollen. The addition of pollen retarded the lipid oxidation and inhibited the bacterial growth in meatballs. The pH, redness, TBA value and total aerobic mesophilic bacteria, coliform bacteria and S. aureus counts values changed significantly during storage. The results suggest that bee pollen could be added to enhance the nutritional and storage quality of meatballs with minimal changes in composition and/or sensory properties.

Evaluation of the Nutritional and Storage Quality of Meatballs Formulated with Bee Pollen

Sadettin Turhan,Fehmi Yazic,Furkan Turker Saricaoglu,Mustafa Mortas,Huseyin Genccelep 한국축산식품학회 2014 한국축산식품학회지 Vol.34 No.4

In this study, the nutritional and storage quality of meatballs formulated with different levels (0, 1.5, 3.0, 4.5 and 6.0%) ofbee pollen were investigated during storage at 41ºC for 9 d. Protein content of meatballs increased, while moisture contentdecreased with increased pollen. The addition of pollen improved cooking loss but decreased the redness (Hunter a value)and sensory scores. Textural parameters (hardness, springsness, gumminess, and chewiness) were affected by pollen additionand the hardness and gumminess values of meatballs decreased as the pollen content increased. While C18:0 content ofmeatballs slightly decreased with pollen addition, C18:2n-6c, C18:3n-3, C20:5n-3, and PUFA contents increased. The PUFA/saturated fatty acids (P/S) ratio increased from 0.05 in the control to 0.09 in meatballs with 6.0% pollen. The n-6/n-3 ratiodecreased from 11.84 in the control to 3.65 in the meatballs with 6.0% pollen. The addition of pollen retarded the lipid oxi-dation and inhibited the bacterial growth in meatballs. The pH, redness, TBA value and total aerobic mesophilic bacteria,coliform bacteria and S. aureus counts values changed significantly during storage. The results suggest that bee pollen couldbe added to enhance the nutritional and storage quality of meatballs with minimal changes in composition and/or sensoryproperties.

The Partial Purification and Properties ofPepsin Obtained from Turkey Proventriculus

Sadettin Turhan,Hasan Temiz,Umut Aykut,Emin Okumus 한국생물공학회 2007 Biotechnology and Bioprocess Engineering Vol.12 No.4

In this study, pepsin from turkey proventriculus was purified, and its biochemical properties examined. Initially, the turkey proventriculus (stomach) was mixed with 10% NaCl (1:2, w/v) and extracted by centrifugation to produce a crude extract. The partial purification of the extract was carried out using Sephadex G-50 resin in gel filtration column chromatography. The fractions obtained by gel filtration were analyzed for milk clotting activity (MCA), protein content, proteolytic activity (PA), purification factor (PF), and SDS-PAGE electrophoresis was also performed. The enzyme was purified 207-fold with a recovery of 36%. The first 4 fractions did not have any activities; fractions 7, 8, and 9 exhibited the highest levels of milk clotting and proteolytic activity. The electrophoretic patterns revealed that further purification steps should be applied for better results.

Versatile p(3-sulfopropyl methacrylate) hydrogel reactor for the preparation of Co, Ni nanoparticles and their use in hydrogen production

Tugce Turhan,Nurettin Sahiner,Yuksel Guvenilir Avcıbası 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.4

In this study, polymeric hydrogels derived from 3-sulfopropyl methacrylate (SPM) were used in the preparation of composite-catalyst system in hydrogen generation from hydrolysis of NaBH4. In order to generate pores and determine their effect on hydrogen production, silica based p(SPM) hydrogels were synthesized also prepared. Additionally, the effects of metal type, temperature, the amount of the catalyst, metal reloading, and reusability were investigated. The activation energy, activation enthalpy,and activation entropy for the hydroylsis reaction of NaBH4 solution in the presence of p(SPM)–Co catalyst system were calculated as 41.67 kJ mol-1, 38.15 kJ mol-1, -173.139 J/mol K, respectively.

Influence of Rootstocks on Yield and Fruit Characteristics and Quality of Watermelon

Ahmet Turhan,Nese Ozmen,Hayrettin Kuscu,Mehmet Sitki Serbeci,Vedat Seniz 한국원예학회 2012 Horticulture, Environment, and Biotechnology Vol.53 No.4

The objective of this study was to examine the effects of grafting and kinds of rootstocks on yield that are economically feasible for the watermelon producer. Fruit characteristics and quality attributes of grafted plants in open field conditions were also analyzed. The tongue approach grafting method was adopted. Three Watermelon cultivars of ‘Crimson Tide’, ‘Dumara’, and ‘Farao’ were used as the scion. Three hybrid squashes of ‘Dynamo’, ‘RS-841’, and ‘Shintosa’ were used as rootstocks. Results showed that some fruit quality indicators such as dry matter, total soluble solids, total sugar and titratable acid contents were lower in grafted plants while lycopene contents remained unchanged. The pH was slightly altered by grafting. Use of rootstock did not show advantages at comparable fruit quality indicators. Results also showed that fruit shape index, rind thickness, fruit weight, total yield and marketable yield were significantly influenced by grafting. Use of rootstocks significantly increased previously mentioned values which is related with yield,as compared to the non-grafted plant. Analyses proved the use of rootstocks as economically feasible and an advantageous alternative in watermelon production.

Predicting Prolonged Wound Drainage after Hemiarthroplasty for Hip Fractures: A Stacked Machine Learning Study

Sultan Turhan,Umut Canbek,Tugba Dubektas-Canbek,Eralp Dogu 대한정형외과학회 2023 Clinics in Orthopedic Surgery Vol.15 No.6

Background: Prolonged wound drainage (PWD) is one of the most important reasons that increase the risk of early periprosthetic joint infection after arthroplasty. It is very important to evaluate the risk factors for PWD in the surgical field after arthroplasty surgery. This can be accomplished using machine learning or artificial intelligence methods. Our aim in this study was to compare machine learning methods in predicting possible PWD. Methods: The study was carried out on clinical, laboratory, and radiological data of 313 patients who underwent hemiarthroplasty (HA) for proximal femur fractures. We preprocessed the dataset and trained and tested machine learning methods using cross validation. We compared various machine learning algorithms (linear discriminant analysis, decision tree, k-nearest neighbors, gradient boosting machine, and logistic regression [LR]) based on performance measures. We also combined the most successful algorithms with a metaclassifier. To help understand the relationship between risk factors, we provided a risk factor severity ranking. Results: To estimate the risk of PWD, classification was performed with first-level classifiers and then integrated as a LR-based meta-learner stacking method. More performance improvements were achieved with the stacking method. Conclusions: We found that the stacking method was superior to other methods in PWD classification. We determined that the volume of fluid collected from the drain, morbid obesity class, blood transfusion, and body mass index score were the four most important risk factors according to stacking.

The Effect of Benzene on the Activity of Adenosine Deaminase in Tissues of Rats

( Ali Turhan ),( Egemen Dere ) 생화학분자생물학회 2007 BMB Reports Vol.40 No.3

Employability of IT graduates from the industry’s perspective: a case study in Turkey

Cigdem Turhan 서울대학교 교육연구소 2013 Asia Pacific Education Review Vol.14 No.4

The qualifications that constitute the employability and identity of graduates are viewed differently by the academic community and the industry. Currently, it is observed for Information Technologies (IT) sector that the demands of the industry are not always satisfied by the perceived standards of the graduates. To provide feedback to the corresponding departments, a survey regarding employer expectations and factors affecting these expectations has been conducted among a number of senior professionals and managers working in the IT sector in Turkey regarding this inconsistency. The employer expectations are considered in two empirical categories as competencies and adequacies. The multiple regression analysis technique has been used to analyze the survey data. Based on the analysis, recommendations are provided to IT departments as well as their students to better fulfill the demands of the industry.

The new Turkish early childhood teacher education curriculum: a brief outlook

Tulay Atay-Turhan 서울대학교 교육연구소 2009 Asia Pacific Education Review Vol.10 No.3

This article aims to describe and reflect on the new early childhood teacher education curriculum in Turkey. The new curriculum is part of a large-scale reform agenda to improve education at all levels. The article begins with a brief history of early childhood education and early childhood teacher education in Turkey. Then, the needs for the curriculum revision and major characteristics of the revised curriculum are discussed. The article concludes with brief discussion about the innovations and suggestions for future research dealing with the implementation and effectiveness of the revised curriculum.