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      • SCIESCOPUSKCI등재

        Updates on Prevention of Cardioembolic Strokes

        Topcuoglu, Mehmet Akif,Liu, Liping,Kim, Dong-Eog,Gurol, M. Edip Korean Stroke Society 2018 Journal of stroke Vol.20 No.2

        <P>Cardiac embolism continues to be a leading etiology of ischemic strokes worldwide. Although pathologies that result in cardioembolism have not changed over the past decade, there have been significant advances in the treatment and stroke prevention methods for these conditions. Atrial fibrillation remains the prototypical cause of cardioembolic strokes. The availability of new long-term monitoring devices for atrial fibrillation detection such as insertable cardiac monitors has allowed accurate detection of this leading cause of cardioembolism. The non-vitamin K antagonist oral anticoagulants have improved our ability to prevent strokes for many patients with non-valvular atrial fibrillation (NVAF). Advances in left atrial appendage closure and the U.S. Food and Drug Administration approval of the WATCHMAN (Boston Scientific) device for stroke prevention in NVAF patients who have an appropriate rationale for a nonpharmacological alternative, have revolutionized the field and provided a viable option for patients at higher hemorrhagic risk. The role of patent foramen ovale closure for secondary prevention in selected patients experiencing cryptogenic ischemic strokes at a relatively young age has become clearer thanks to the very recent publication of long-term outcomes from three major studies. Advances in the management of infective endocarditis, heart failure, valvular diseases, and coronary artery disease have significantly changed the management of such patients, but have also revealed new concerns related to assessment of ischemic versus hemorrhagic risk in the setting of antithrombotic use. The current review article aims to discuss these advances especially as they pertain to the stroke neurology practice.</P>

      • KCI등재

        The use of ferrocement in the construction of squat grain silos

        Kıvanc Topcuoglu,Halil Baki Unal 사단법인 한국계산역학회 2016 Computers and Concrete, An International Journal Vol.18 No.1

        In this study, an investigation is made from the statics and economic aspects of the possibility of using the composite material ferrocement on the surfaces of squat cylindrical grain silos. For this purpose, the geometry of two model silos, each of height 5 m and diameter 5 m and 12.5 m, was designed. Five different reinforced plates of 10 and 20 mm thickness were produced to research the most suitable ferrocement plates to be used on the surface of these silos. Most durable reinforcement type for covering the silo surface was determined by pressure and bending tests. Grade 30 and Grade 55 steel plates were also considered for use in covering steel-coated silos. In the statics analysis performed with SAP2000, the least plate thicknesses needed for silos surfaced with Grade 30 and Grade 55 steel were found to be 6.20 mm and 4.70 mm respectively for silos of diameter 5 m, and 6.70 mm and 5.00 mm for silos of diameter 12.5 m. In the economic analysis, it was found that 20 mm thick Type 4 (with a wire diameter of 0.30 mm and a mesh aperture of 2 mm x 2 mm square type) reinforced ferrocement surfacing material was 5.6-6.1 times more economical than Grade 30 steel surfacing material and 4.4-4.7 times more economical than using Grade 55 steel. These results show that ferrocement can be used in place of steel from the point of view both of statics and economy.

      • KCI등재후보

        Clinical challenges associated with the endovascular treatment of acute stroke in a patient with infective endocarditis

        Emil Settarzade,Ahmet Peker,M. Akif Topcuoglu,E. Murat Arsava,Metin Demircin,Anıl Arat 대한뇌혈관외과학회 2020 Journal of Cerebrovascular and Endovascular Neuros Vol.22 No.3

        Although stroke is common in infective endocarditis (IE), only 26 cases of thrombectomy have been reported to date for IE-related acute stroke. We report a 40-year-old man who presented with left middle cerebral artery occlusion of unknown cause. Multiple attempts of mechanical aspiration thrombectomy and stentrievers failed to recanalize the artery. Effective revascularization was eventually achieved by placing a self-expanding intracranial stent. Post-procedurally the patient was diagnosed with IE with mitral valve insufficiency, mandating emergent valvular replacement while the patient was still on tirofiban infusion. On follow-up, the patient had a modified Rankin’s score of 0, had no recurrent stroke, and the intracranial stent remained patent yet stenosed. Based on the use of a self-expanding intracranial stent in the setting of IE, we discuss the consequences of the fibrotic and inflammatory content of the embolus and the associated high risk of intracranial hemorrhage which complicates clinical decision making.

      • SCOPUSSCIEKCI등재

        Comparison of retention characteristics of Essix and Hawley retainers

        Demir, Abdullah,Babacan, Hasan,Nalcaci, Ruhi,Topcuoglu, Tolga The Korean Association Of Orthodontists 2012 대한치과교정학회지 Vol.42 No.5

        Objective: We aimed to compare the retention characteristics of Essix and Hawley retainers. Methods: Adolescents undergoing fixed appliance treatment at 2 centers were recruited for this study. Twenty-two patients (16 women and 6 men) wore Essix retainers (Essix group) while 20 (14 women and 6 men) wore Hawley retainers (Hawley group). The mean retention time was 1 year, and the mean follow-up recall time for both groups was 2 years. Two qualified dental examiners evaluated the blind patient data. Maxillary and mandibular dental casts and lateral cephalograms were analyzed at 4 stages: pretreatment (T1), post-treatment (T2), post-retention (T3), and follow-up (T4). Results: The results revealed that Essix appliances were more efficient in retaining the anterior teeth in the mandible during a 1-year retention period. The irregularity index increased in both arches in both groups after a 2-year post-retention period. The mandibular arch lengths increased during treatment and tended to return to their original value after retention in both groups; however, these changes were statistically significant only in the Hawley group. Cephalometric variables did not show any significant differences. Conclusions: The retention characteristics of both Essix and Hawley retainers are similar.

      • KCI등재

        Comparison of retention characteristics of Essix and Hawley retainers

        Abdullah Demir,Hasan Babacan,Ruhi Nalcacı,Tolga Topcuoglu 대한치과교정학회 2012 대한치과교정학회지 Vol.42 No.5

        Objective: We aimed to compare the retention characteristics of Essix and Hawley retainers. Methods: Adolescents undergoing fixed appliance treatment at 2 centers were recruited for this study. Twenty-two patients (16 women and 6 men) wore Essix retainers (Essix group) while 20 (14 women and 6 men) wore Hawley retainers (Hawley group). The mean retention time was 1 year, and the mean follow-up recall time for both groups was 2 years. Two qualified dental examiners evaluated the blind patient data. Maxillary and mandibular dental casts and lateral cephalograms were analyzed at 4 stages: pretreatment (T1), post-treatment (T2), post-retention (T3), and follow-up (T4). Results: The results revealed that Essix appliances were more efficient in retaining the anterior teeth in the mandible during a 1-year retention period. The irregularity index increased in both arches in both groups after a 2-year post-retention period. The mandibular arch lengths increased during treatment and tended to return to their original value after retention in both groups; however, these changes were statistically significant only in the Hawley group. Cephalometric variables did not show any significant differences. Conclusions: The retention characteristics of both Essix and Hawley retainers are similar.

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