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      • KCI등재

        A Proteomic Analysis of Leaf Responses to Enhanced Ultraviolet-B Radiation in Two Rice (Oryza sativa L.) Cultivars Differing in UV Sensitivity

        Xing-Chun Wu,Chang-Xun Fang,Jin-Yang Chen,Qing-Shui Wang,Ting Chen,Wen-Xiong Lin,Zhong-Liang Huang 한국식물학회 2011 Journal of Plant Biology Vol.54 No.4

        To determine the proteomic response to UV irradiation, two cultivars, i.e., Lemont (UV tolerant) and Dular (UV sensitive), were exposed to natural and enhanced ultraviolet-B (UV-B) irradiation for 1, 7, and 14 days, and two-dimensional gel electrophoresis in combination with mass spectrometry (MS) and bioinformatics were used to compare the different proteomic responses in the leaves of the two cultivars. Thirty-nine proteins were up- or downregulated following the UV-B treatments. Among them, 30 increased or decreased more than 1.5-fold in abundance. They were further tested by using matrix-assisted laser desorption/ionization time of flight MS and performed a database search. Twentyfour proteins were thus identified. These identified proteins were mostly upregulated in Lemont, whereas only 14 of them upregulated in Dular. Nine proteins involved in glycometabolism and fatty acid metabolisms, signal transduction, and protein synthesis and folding in Dular were not changed. These results suggest that there was a complex regulative mechanism on the proteomes in rice leaves upon UV-B exposure.

      • KCI등재

        The Determinants of South Korea’s Trade Balance: A Cointegrating Regression Approach

        Ting-Huan Chang,Jun-De Lee,Yi-Hsien Wang 한국무역학회 2012 Journal of Korea trade Vol.16 No.3

        This paper examines the key determinants of South Korea’s trade balance using three fully efficient cointegrating regression methods. We find that the trade balance, foreign income, money supply, real effective exchange rate, and domestic income are cointegrated. Consistent with the Marshall-Lerner condition, appreciation in the real effective exchange rate is negatively related to the trade balance. Our results have important implications for using exchange rate policy as a device to achieve trade balance.

      • KCI등재
      • KCI등재

        Comparison of the trometamol-balanced solution with two other crystalloid solutions for fluid resuscitation of a rat hemorrhagic model

        Wen-Ting Ting,Ru-Wen Chang,Chih-Hsien Wang,Yih-Sharng Chen,Jih-Jong Lee 대한수의학회 2020 Journal of Veterinary Science Vol.21 No.1

        Currently, the optimal resuscitation fluid remains debatable. Therefore, in the present study, we designed a trometamol-balanced solution (TBS) for use as a resuscitation fluid for hemorrhagic shock. Hemorrhagic shock was induced in 18 male Wistar-Kyoto rats, which were assigned to normal saline (NS), Ringer's solution (RS), and TBS groups. During the hemorrhagic state, their hemodynamic parameters were recorded using an Abbott i-STAT analyzer with the CG4+ cartridge (for pH, pressure of carbon dioxide, pressure of oxygen, total carbon dioxide, bicarbonate, base excess, oxygen saturation, and lactate), the CG6+ cartridge (for sodium, potassium, chloride, blood glucose, blood urea nitrogen, hematocrit, and hemoglobin), and enzyme-linked immunosorbent assay kits (calcium, magnesium, creatinine, aspartate aminotransferase, alanine aminotransferase, bilirubin, and albumin). Similar trends were found for the parameters of biochemistries, electrolytes, and blood gas, and they revealed no significant changes after blood withdrawal-induced hemorrhagic shock. However, the TBS group showed more effective ability to correct metabolic acidosis than the NS and RS groups. TBS was a feasible and safe resuscitation solution in this study and may be an alternative to NS and RS for resuscitation in hemorrhagic shock patients without liver damage.

      • KCI등재후보

        한국과 중국 중등교사 양성제도의 비교

        류팅팅 ( Ting Ting Liu ),박창언 ( Chang Un Park ) 부산대학교 과학교육연구소 2013 교사교육연구 Vol.52 No.3

        본 연구는 한국과 중국의 중등교사 양성제도를 비교함으로써 양국의 상호이해와 시사점을 도출하는데 목적이 있다. 이 목적 달성을 위해 한국과 중국의 중등교사 양성의 변천에 대한 경과를 살펴보고, 교사 자격제도 및 중등교사 양성을 위한 교육과정을 비교하였다. 비교 결과 공통적인 사항으로는 양국이 모두 교원자격에 대해 법정화 함으로서 교원의 지위를 보장하기 위한 조치를 취하고 있었다. 또한 교육학과 교과내용학 모두를 중시하고 있었다. 이에 비해 차이점으로는 교원자격검정에서 한국은 무시험검정으로 자격을 부여하는데 비해, 중국은 시험을 통해 자격을 부여하고, 그 자격도 일정기간이 경과하면 갱신하여야 하였다. 교원 양성기관에서도 한국은 대부분의 대학에서 동일한 내용을 가르치지만, 중국은 국가급, 성급, 시급 등으로 구분이 되고, 이들 기관별 교육내용이 상이하게 전개되었다. 또한 시급으로 갈수록 실습에 대한 과목이 많이 부여되었다. 특징적인 것은 한국의 교원양성 교육과정에서는 이념과 관련된 과목이 존재하지 않는데 비해, 중국의 교원양성 교육과정에서는 이념과 관련된 과목이 존재하고 있었다. 이수학점은 한국에 비해 중국이 월등히 많았다. 이러한 공통점과 차이점을 토대로 양국은 국가별 상황을 고려하되, 양국의 좋은 제도적 취지나 내용은 수용하여 각국의 교원의 전문적 자질을 함양하는데 적극 활용할 필요가 있었다. The purpose of this study is to analyze the similarities and differences of the teacher`s training system between Korea and China in middle and high school teacher. The specific research of this study are as follows. Firstly, what are the similarities and differences of the teacher`s certification system, Secondly, what are the similarities and differences of the teacher education curriculum. The finding are as follows. First, there are similarities in teacher`s certification system between the two nations: (1) the teacher`s certificate are awarded through official approval, (2) each nation bothered about the teaching profession subjects and major Secondary, there are many differences in the teacher education curriculum between two nations; (1) Korea has a certification system without examination, while China has a certification system with examination, (2) Korea has an easy courses to acquire an upper certificate, while China has an hard courses to acquire an upper certificate, (3) the kinds of certificate are various in Korea, while China has a certification system with examination, (4) Korea has not a subject related with ideologies, while China has a subject for ideologies.

      • KCI등재

        Comparison between residents with a 6-year medical program and a 7-year medical program in terms of objective structured clinical examination performance in postgraduate year training in Taiwan: a 2-group pre- and post-test non-synchronized study

        Ya-Ting Chang,Ying-Ying Yang,Chung-Pin Li,Chen-Huan Chen 한국보건의료인국가시험원 2022 보건의료교육평가 Vol.19 No.-

        Purpose In 2013, medical schools in Taiwan implemented a 6-year medical program that replaced the previous 7-year medical education program. The postgraduate year (PGY) program was also extended from 1 year to 2 years. The new program is characterized by diversified teaching, integration of medical skills, a system-oriented curriculum, and the implementation of primary care and clinical thinking training. The purpose of this study was to examine whether postgraduate residents who learned under the new program have better patient care skills than those who learned under the previous program. Methods Of 101 residents in the PGY program at Taipei Veterans General Hospital, 78 were trained in the 6-year program, while 23 were trained in the 7-year program. During the PGY training, 2 objective structured clinical examinations (OSCEs) were used to evaluate clinical reasoning, communication skills, and procedural skills at the beginning of the training and after 11 months of training, respectively. The scores of each OSCE and the rate of improvement of the pre- and post-tests were analyzed. Results Residents trained in the new program scored higher on clinical reasoning (P<0.001) and the total scores of the 3 tested skills (P=0.019) on the pre-test. In terms of improvement, residents educated in the previous system improved more in clinical reasoning than those educated in the new education system. Conclusion The new medical education program, which emphasizes clinical thinking, improved residents’ clinical skills. The PGY program was effective in improving the clinical performance of residents who were educated in the previous system.

      • KCI등재

        Evaluating the effects of programs for reducing achievement gaps: a case study in Taiwan

        Yao-Ting Sung,Fen-Lan Tseng,Nien-Ping Kuo,Tien-Ying Chang,Jia-Min Chiou 서울대학교 교육연구소 2014 Asia Pacific Education Review Vol.15 No.1

        Considering that achievement gaps have become a serious educational problem worldwide, the Ministry of Education in Taiwan has been addressing a series of policies to reduce achievement gaps, but the effect of these policies has not yet been carefully examined. Therefore, the present study investigated current educational policies, achievement gap phenomenon, and its changing trends in the use of national standardized tests in Taiwan and evaluated the degree to which these policies are reducing the achievement gaps among Taiwanese students. Junior high school graduates who took the high school entrance examination between 2004 and 2010 were recruited to examine the associations between their academic achievements and variables such as socioeconomic status (SES), ethnicity, and school district. Time series analyses were conducted to determine the longitudinal trends for the achievement gaps. The results revealed that achievement gaps are decreasing among different ethnicities, but they are increasing among different SESs and school districts. These findings demonstrate some positive effects of the educational policies introduced in Taiwan, but also the need for further modification and precise implementation of these policies. Suggestions for implementing educational programs and policies to reduce achievement gaps are also presented.

      • KCI등재

        Effectiveness of N-acetylcysteine in Treating Clinical Symptoms of Substance Abuse and Dependence: A Meta-analysis of Randomized Controlled Trials

        Chung-Ting Chang,Pei-Ju Hsieh,Hsin-Chien Lee,Chun-Hong Lo,Ka-Wai Tam,El-Wui Loh 대한정신약물학회 2021 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.19 No.2

        Objective: Treatment with N-acetylcysteine (NAC) is believed to reduce the clinical symptoms among individuals with substance abuse or dependence. We conducted a meta-analysis of randomized controlled trials to evaluate the effective-ness of NAC in treating substance abuse and dependence. Methods: PubMed, EMBASE, ClinicalTrials.gov registry, and the Cochrane Library were searched for trials published before June 2020. Results: A total of 16 trials were analyzed. The treatment effectiveness domains assessed in this study were craving and depressive symptoms, withdrawal syndrome, adverse events, and smoking frequency. Standardized mean difference (SMD), weighted mean difference (WMD), and odds ratio (OR) were used for evaluation where appropriate. A significant decrease in craving symptoms was observed in the NAC treatment group compared with the control group (SMD, −0.67; 95% confidence interval [CI], −1.21 to 0.21). When withdrawal and depressive symptoms were considered as a single domain, the NAC treatment group demonstrated a significantly higher overall improvement than the control group (SMD, −0.35; 95% CI, −0.64 to −0.06). No between-group differences in term of the OR of adverse events (OR, 1.18; 95% CI, 0.68 to 2.06) and a non-significant trend toward reduction in smoking frequency was observed in the NAC treatment group compared with the control group (WMD, −3.09; 95% CI, −6.50 to 0.32). Conclusion: NAC provides certain noticeable benefits in attenuating substance craving and might help alleviate depres-sive symptoms and withdrawal syndrome. Precautious measures should be considered when using NAC although no difference in adverse effects was found between NAC treatment and control group.

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