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      • Mitigating SYN flooding Attack and ARP Spoofing in SDN Data Plane

        Ting-Yu Lin,Jhen-Ping Wu,Pei-Hsuan Hung,Ching-Hsuan Shao,Yu-Ting Wang,Yun-Zhan Cai,Meng-Hsun Tsai 한국통신학회 2020 한국통신학회 APNOMS Vol.2020 No.09

        As the number of network devices increases rapidly, it becomes more and more difficult to defend network attacks. Large-scaled attacks, such as SYN flooding, may lead to heavy burden to the switches as well as the controller in a software defined network (SDN). In this paper, we investigate the SYN flooding and Address Resolution Protocol (ARP) spoofing attacks in SDN, and then propose mechanisms to address these two attacks. We also present a new scheme to detect SYN flooding by using only a few forwarding rules. Moreover, we utilize the Programming Protocol-independent Packet Processors (P4) technique to mitigate the burden of the controller.

      • KCI등재

        Allergic Identification for Ginkgo Kernel Protein in Guinea Pigs

        Cai-e Wu,Jian-Ting Yang,Gong-Jian Fan,Ting-Ting Li,Zhen-Xing Tang,Fu-Liang Cao 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.3

        Ginkgo biloba L. can cause allergic reactions when consumed. In this paper, an allergy test to guinea pig was investigated. Guinea pigs were sensitized with 50 mg/mL of ginkgo kernel protein orally on days 1, 3, and 5, and intraperitoneally challenged with 100mg/mL of the protein on day 7 after the last sensitization. The volume of sensitization and challenge was 0.20mL/100 g weight. The results showed the average allergy grade for guinea pigs reached four and the allergy rate was 100%. The immunoglobulin G and E levels in sera were significantly higher than those in the controls. Footpads swelled distinctly, and the passive cutaneous allergy test manifested a positive response. There were inflammatory changes in the lungs and intestines. In conclusion, the present results may indicate that gingko kernel protein has an allergenic capacity.

      • The compressive strength of concrete retrofitted with wind ash and steel slag pozzolans with a water-cement based polymers

        Cai, Ting,Zandi, Yousef,Agdas, Alireza Sadighi,Selmi, Abdellatif,Issakhov, Alibek,Roco-Videla, Angel Techno-Press 2021 Advances in concrete construction Vol.11 No.6

        Freeze and thaw phenomena in cold regions are the main cause of severe damage to concrete structures. Alkali-activated slag repair mortars, which are introduced as a suitable material for the replacement of Portland cement, can be used as the protective coating for these damaged structures. The mechanical properties and durability of this coating layer should be studied. In this study, the mechanical properties and durability of alkali-activated slag repair mortars with silica fume (SF) participation as inorganic additives against freeze-thaw and salt scaling attacks have been investigated. In order to evaluate the effects of alkaline activators type, the ratio of these solutions to Pozzolan (Pozz), and the use of SF as a substitute base material, these three factors were considered as the main variables to produce 12 alkali-activated slag mortar mixtures. To investigate their mechanical properties, compressive strength, tensile adhesion strength, and drying shrinkage tests were conducted. Also, mortar specimen length change, compressive strength loss, weight loss, and dynamic elastic modulus were measured to evaluate the durability features against freeze-thaw and salt scaling attacks. According to the results, in addition to higher compressive strength and adhesion resistance of alkali-activated slag repair mortars, these mortars showed at least 30% better durability against freeze-thaw and salt scaling attacks than cement-based repair mortar. Also, alkali-activated slag mixtures containing potassium hydroxide, alkaline solution (AS) to Pozz ratio of 0.7, and SF had the best mechanical properties and frost resistance among all mixtures.

      • A Hybrid Attribute based RBAC Model

        Ting Cai,Jian Zheng,Xing Du 보안공학연구지원센터 2015 International Journal of Security and Its Applicat Vol.9 No.7

        In an open and distributed network, role-based access control (RBAC) model has the following deficiencies: Firstly, it is unable to provide flexible access control policy, and the granularity of authorization is too large. Secondly, the allocation and management of roles are too cumbersome, which leads to low efficiency of access control. To deal with these problems, we present a hybrid attribute based RBAC (HA-RBAC) model. In this paper, we deeply research the mapping relationships of roles and attributes, propose a combination of static-attribute-based roles and dynamic-attribute-based rules to simplify the management of access control policy and downsize the access control system, while we formally define the construction of HA-RBAC model and access control algorithm. Comparative analysis and simulation experiments show that this model can not only adapt to the role of fine-grained division and simplify policy management, but also improve the efficiency of access control, and reduce system consumption.

      • SCIESCOPUSKCI등재

        Immunohistochemical detection of GluA1 subunit of AMPA receptor in the rat nucleus accumbens following cocaine exposure

        Wen Ting Cai,Joonyeup Han,Wha Young Kim,Jeong-Hoon Kim 대한약리학회 2021 The Korean Journal of Physiology & Pharmacology Vol.25 No.1

        α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors are differentially regulated in the nucleus accumbens (NAcc) of the brain after cocaine exposure. However, these results are supported only by biochemical and electrophysiological methods, but have not been validated with immunohistochemistry. To overcome the restriction of antigen loss on the postsynaptic target molecules that occurs during perfusion-fixation, we adopted an immersion-fixation method that enabled us to immunohistochemically quantify the expression levels of the AMPA receptor GluA1 subunit in the NAcc. Interestingly, compared to saline exposure, cocaine significantly increased the immunofluorescence intensity of GluA1 in two sub-regions, the core and the shell, of the NAcc on withdrawal day 21 following cocaine exposure, which led to locomotor sensitization. Increases in GluA1 intensity were observed in both the extra-post synaptic density (PSD) and PSD areas in the two sub-regions of the NAcc. These results clearly indicate that AMPA receptor plasticity, as exemplified by GluA1, in the NAcc can be visually detected by immunohistochemistry and confocal imaging. These results expand our understanding of the molecular changes occurring in neuronal synapses by adding a new form of analysis to conventional biochemical and electrophysiological methods.

      • SCIESCOPUSKCI등재

        Broad-Spectrum Activity of Volatile Organic Compounds from Three Yeast-like Fungi of the Galactomyces Genus Against Diverse Plant Pathogens

        ( Shu-ting Cai ),( Ming-chung Chiu ),( Jui-yu Chou ) 한국균학회 2021 Mycobiology Vol.49 No.1

        The application of antagonistic fungi for plant protection has attracted considerable interest because they may potentially replace the use of chemical pesticides. Antipathogenic activities confirmed in volatile organic compounds (VOCs) from microorganisms have potential to serve as biocontrol agents against pre- and post-harvest diseases. In the present study, we investigated Galactomyces fungi isolated from rotten leaves and the rhizosphere of cherry tomato (Lycopersicon esculentum var. cerasiforme). VOCs produced by Galactomyces fungi negatively affected the growth of phytopathogenic fungi and the survival of nematodes. Mycelial growths of all nine examined phytopathogenic fungi were inhibited on agar plate, although the inhibition was more intense in Athelia rolfsii JYC2163 and Cladosporium cladosporioides JYC2144 and relatively moderate in Fusarium sp. JYC2145. VOCs also efficiently suppressed the spore germination and mycelial growth of A. rolfsii JYC2163 on tomatoes. The soil nematode Caenorhabditis elegans exhibited higher mortality in 24 h in the presence of VOCs. These results suggest the broad-spectrum activity of Galactomyces fungi against various plant pathogens and the potential to use VOCs from Galactomyces as biocontrol agents.

      • KCI등재

        Experimental study on fabrication of large-scale micro cylinders array by mask jet electrochemical deposition

        Ting Huang,Zhongning Guo,Guiming Liang,Shunzhi Qiao,Pengcheng Cai,Zhixiang Zou 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.8

        The mask jet electrochemical deposition was used to deposit the large-scale micro cylinders array in this study. The effect of the pulse peak current density, pulse frequency, pulse duty cycle, injection pressure and scanning speed on the deposition characteristics (i.e. deposition height, surface roughness and surface quality of micro cylinders) have been investigated. The experiment results showed that the mean height and the surface roughness of micro cylinders increased form the peak current density. Moreover, due to a high pulse frequency provided a shorter pulse on-time, and significantly facilitating the renewal of the ion concentration in the electroforming fluid. A higher pulse frequency and larger duty cycle provide a better deposition characteristic. The injection pressure was found to have a significant effect on the height, the surface roughness and surface appearance of micro cylinders. Furthermore, when using higher scanning speed, the crystalline particles of the cast layer decrease, significantly decreasing the surface roughness. Based on discussed, the pulse current density of 12 A/dm 2 , a pulse frequency of 3000 Hz, a pulse duty cycle of 30 %, a jet inlet pressure of 80 kPa, a scanning speed of 8 mm/s and a number of scans of 100 is optimal parameters. Finally, by using these parameters, a large-area micro cylindrical array structures with a height of 22.53±2.46 μm and diameter of 205±3.21 μm were successfully fabricated. It can be concluded that the mask jet electrochemical deposition is a simple method to realize the electrodeposition of large-area array structures.

      • KCI등재

        Photo-induced antifouling polyvinylidene fluoride ultrafiltration membrane driven by weak visible light

        Ting Wang,Ling-li Jiang,Lu-lu Huang,Li-guang Wu,Chun-juan Li,Jing Cai 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.89 No.-

        To enhance the performance of ultrafiltration membranes, a polyvinylidenefluoride (PVDF) blendingmembrane with photo-induced antifouling performance was fabricated. La3+- and Yb3+-doped titaniumdioxide-reduced graphene oxide (TiO2-RGO) composites were initially prepared by adsorption-phasesynthesis coupled with solvothermal reduction. The doped TiO2-RGO composites were then blendedwith the PVDF materials. The results showed that adding well-distributed, doped, and hydrophilic TiO2-RGO improved the pore structures and surface polarity of the blending membranes, thus improving theirpermeation and antifouling performance. After addition of doped TiO2-RGO with photocatalytic activity,the antifouling performance of the resulting blending membranes increased under weak visible-lightirradiation. The agglomerated doped TiO2-RGO in the polymeric matrix reduced the hydrophilicity andporosity of the resulting membranes, thereby decreasing their water permeability and antifoulingperformance. Solvothermal reduction through ethylene glycol also improved the photocatalytic activityof Yb-doped TiO2-RGO and enhanced the affinity between doped TiO2-RGO and PVDF. These two effectssimultaneously increased the water permeability and photo-induced antifouling performance of theblending membranes. Theflux recovery rate of the blending membranes containing Yb-doped TiO2-RGOtreated by ethylene glycol exceeded 69% after illumination. In particular, theflux recovery rate ofmembranes reached about 96% after illumination coupling with washing.

      • KCI등재

        Mannich reaction catalyzed by a novel catalyst under solvent-free conditions

        Cai Bo Yue,Ting Feng Yi,Chuan Bing Zhu,Gang Liu 한국공업화학회 2009 Journal of Industrial and Engineering Chemistry Vol.15 No.5

        An acidic catalyst [Py][CF3COO] (pyridinium trifluoroacetate) was synthesized and used in the Mannich reaction of various kinds of aromatic aldehydes, aromatic ketones and aromatic amines. b-Amino carbonyl compounds were obtained in reasonable yields when the Mannich reaction was carried out at room temperature under solvent-free conditions. The products could be separated from the catalyst simply via washing with water and after removing water, the catalyst could be recycled and reused for up to four times without noticeably decreasing in catalytic activity.

      • KCI등재

        A Single-Arm Phase II Study of Nab-Paclitaxel Plus Gemcitabine and Cisplatin for Locally Advanced or Metastatic Biliary Tract Cancer

        Ting Liu,Qing Li,Zhen Lin,Chunhua Liu,Wei Pu,Shasha Zeng,Jun Lai,Xuebin Cai,Lisha Zhang,Shuyang Wang,Miao Chen,Wei Cao,Hongfeng Gou,Qing Zhu 대한암학회 2024 Cancer Research and Treatment Vol.56 No.2

        Purpose Patients with advanced biliary tract cancer (BTC) have a poor survival. We aim to evaluate the efficacy and safety of nab-paclitaxel plus gemcitabine and cisplatin regimen in Chinese advanced BTC patients.Materials and Methods Eligible patients with locally advanced or metastatic BTC administrated intravenous 100 mg/m<sup>2</sup> nab-paclitaxel, 800 mg/m<sup>2</sup> gemcitabine, and 25 mg/m<sup>2</sup> cisplatin every 3 weeks. The primary endpoint was progression-free survival (PFS). The secondary endpoints included overall survival (OS) and adverse events, while exploratory endpoint was the association of biomarkers with efficacy.Results After the median follow-up of 25.0 months, the median PFS and OS of 34 enrolled patients were 7.1 months (95% confidence interval [CI], 5.4 to 13.7) and 16.4 months (95% CI, 10.9 to 23.6), respectively. The most common treatment-related adverse events at ≥ 3 grade were neutropenia (26.5%) and leukopenia (26.5%). Survival analyses demonstrated that carcinoembryonic antigen (CEA) levels could monitor patients’ survival outcomes. A significant increase in the number of infiltrating CD4+ cells (p=0.008) and a decrease in programmed death-1–positive (PD-1+) cells (p=0.032) were observed in the response patients.Conclusion In advanced BTC patients, nab-paclitaxel plus gemcitabine and cisplatin regimen showed therapeutic potential. Potential prognostic factors of CEA levels, number of CD4+ cells and PD-1+ cells may help us maximize the efficacy benefit.

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