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      • KCI등재

        Monthly distribution of ammonia-oxidizing microbes in a tropical bay

        Tie-Qiang Mao,Yan-Qun Li,Hong-Po Dong,Wen-Na Yang,Li-Jun Hou 한국미생물학회 2021 The journal of microbiology Vol.59 No.1

        Ammonia oxidation, performed by ammonia-oxidizing archaea (AOA) and bacteria (AOB), plays a critical role in the cycle of nitrogen in the ocean. For now, environmental variables controlling distribution of ammonia-oxidizing microbes are still largely unknown in oceanic environments. In this study, we used real-time quantitative PCR and high-throughput sequencing methods to investigate the abundance and diversity of AOA and AOB from sediment and water in Zhanjiang Bay. Phylogenic analysis revealed that the majority of AOA amoA sequences in water and sediment were affiliated with the genus Nitrosopumilus, whereas the Nitrosotalea cluster was only detected with low abundance in water. Nitrosomonas and Nitrosospira dominated AOB amoA sequences in water and sediment, respectively. The amoA copy numbers of both AOA and AOB varied significantly with month for both sediment and water. When water and sediment temperature dropped to 17– 20°C in December and February, respectively, the copy number of AOB amoA genes increased markedly and was much higher than for AOA amoA genes. Also, AOA abundance in water peaked in December when water temperature was lowest (17–20°C). Stepwise multiple regression analyses revealed that temperature was the most key factor driving monthly changes of AOA or AOB abundance. It is inferred that low water temperature may inhibit growth of phytoplankton and other microbes and so reduce competition for a common substrate, ammonium.

      • KCI등재

        Research on method of constraint conversion in feature-based data exchange between heterogeneous CAD systems

        Wei Sun,Tie-qiang MA,Yu-jun Huang 대한기계학회 2009 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.23 No.1

        Data exchange between heterogeneous CAD systems is the key problem in the field of CAD, and the popular solution to this problem is a feature-based method. Aiming at keeping the consistency of design intent in data exchange between heterogeneous CAD systems, this research focuses on the method of constraint conversion. First, two kinds of basic feature transformation ways are summarized, and this is the foundation of constraint conversion. Second, a novel identification of geometric elements based on the improved geometric certificate is proposed, and the identifier of geometric element is used to recognize the acting object of constraint. Third, the principles of constraint conversion are put forward, and the method of constraint conversion for a single feature is proposed according to the principles. Fourth, an algorithm of constraint conversion for the whole process of CAD data exchange is designed. Finally, the contrast experiment of CAD data exchange is completed, and the result of the experiment shows that the approach mentioned above is effective.

      • KCI등재

        Experimental and Theoretical Studies of Bidirectional Variable Curvature Friction Pendulum Bearing

        Shu-Chao Lin,Jian-Qiang Han,Hong-tie Zhao 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.5

        In this study, to satisfy the base isolation demand of large-scale building structures under different earthquake records, a new bidirectional variable curvature friction pendulum bearing (BD-VCFPB) is proposed. The VCFPB is designed in detail based on the basic principle of a friction pendulum system. Moreover, the sliding interface function, gap between the slider and the sliding interface, and polytetrafluoroethylene (PTFE) plate stress are studied. Finally, a dynamic cyclic test is conducted to study the influence of the slider size, contact pressure on the PTFE plate, and loading frequency on the hysteretic behavior of the VCFPB. The results indicate that the hysteretic curves of the horizontal force and the displacement are regular, symmetrical, stable, and full, and clearly reflect the variable curvature convex and concave characteristics and the excellent behavior of energy dissipation of the BD-VCFPB. The sliding friction coefficient varies significantly with the contact pressure on the PTFE plate and the loading frequency; however, it has little relation with the slider size. A hysteretic model is proposed based on the results of a unidirectional test, and it is in good agreement with the hysteretic curves of the horizontal force and the displacement from a bidirectional test.

      • KCI등재

        New Chemical Constituents from the Rhizomes of Sparganium stoloniferum

        Ying Xiong,Ke-Zhong Deng,Yuan-Qiang Guo,Wen–Yuan Gao,Tie-Jun Zhang 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.5

        A new sucrose ester named β-D-(1-O-acetyl-3-O-cis-feruloyl)fructofuranosyl α-D-2',3',6'-O-triacetylglucopyranoside 1 and a novel phenylpropanoid glycerol named 1-O-cis-feruloyl-3-Otrans- p-coumaroylglycerol 2, have been isolated from Sparganium stoloniferum. Their structures were elucidated by spectroscopic methods.

      • KCI등재

        Predictive and Prognostic Roles of Pathological Indicators for Patients with Breast Cancer on Neoadjuvant Chemotherapy

        Xinyan Li,Mozhi Wang,Mengshen Wang,Xueting Yu,Jingyi Guo,Tie Sun,Litong Yao,Qiang Zhang,Yingying Xu 한국유방암학회 2019 Journal of breast cancer Vol.22 No.4

        Currently, neoadjuvant chemotherapy is a standard therapeutic strategy for breast cancer, as it can provide timely and individualized chemo-sensitivity information and is beneficial for custom-designing subsequent treatment strategies. To accurately select candidates for neoadjuvant chemotherapy, the association between various immunohistochemical biomarkers of primary disease and tumor response to neoadjuvant chemotherapy has been investigated, and results have shown that certain pathological indicators evaluated after neoadjuvant chemotherapy are associated with long-term prognosis. The Food and Drug Administration (FDA) has recommended that complete pathological response can be used as a surrogate endpoint for neoadjuvant chemotherapy, which is related to better prognosis. Considering that residual tumor persists in the majority of patients after neoadjuvant chemotherapy, the value of various pathological indicators of residual disease in predicting the long-term outcomes is being extensively investigated. This review summarizes and compares various predictive and prognostic indicators for patients who have received neoadjuvant chemotherapy, and analyzes their efficacy in different breast cancer subtypes.

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